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A stretchable electronic facial mask (SEFM) for skin electroporation by transdermal drug delivery is introduced. The SEFM exhibits characteristics of reusability, water‐resistant, low cost, and portability. To achieve these objectives while maintaining satisfactory mechanical and electrical performance of the device, two main areas are innovated: (1) Grinding and doping modification of conductive ink to enhance its adhesion to silicone and increase conductivity through material research, as well as mechanical structure design for stretching stability of conductive ink electrodes. (2) Doping modification of high‐temperature vulcanizes silicone to address the issue of increased resistance during encapsulation due to the swell of conductive ink. The SEFM designed with these innovations, is validated in rat experiments, demonstrating a 3–4 times increase in drug intake compared to the control group without skin electroporation. Safety is confirmed, and the promotion of niacinamide drug delivery is verified in human volunteers. The materials‐modified conductive ink and conductive silicone proposed in SEFM can be employed in other flexible wearable devices, and this platform has the potential for future integration of additional components to achieve expanded functionality and productization. [ABSTRACT FROM AUTHOR]

Stretchable inorganic electronics are usually designed and calibrated under free interface condition, while the interface conditions between the devices and skins/organs in practical applications are rather complex (free, slidable, or bonded) and may switch among them. In the ideal situation, the mechanical and electrical performances have to be consistent under different interface conditions, to ensure the accuracy and robustness of the devices. Here, the effect of interface conditions on the mechanical and electrical performances is studied for stretchable inorganic electronics with different configurations by theoretical analysis, finite element analysis and experiment. A universal size design principle is proposed for stretchable inorganic electronics to work consistently under different interface conditions, i.e., the period length of the devices/interconnects has to be the same order of magnitude as the encapsulation thickness or less. To ensure the comfort of human skin/organs, micron‐scale geometrical design is necessary for epidermal electronics according to the above designed principle. This finding is of great significance for ensuring the accuracy and robustness of stretchable inorganic electronics in practical applications. [ABSTRACT FROM AUTHOR]

Reactive dissolution and its effects on electrical conduction, morphological change and chemical transformation in thin films of Mg, AZ31B Mg alloy, Zn, Fe, W, and Mo in de-ionized (DI) water and simulated body fluids (Hanks' solution pH 5-8) are systematically studied, to assess the potential for use of these metals in water-soluble, that is, physically "transient", electronics. The results indicate that the electrical dissolution rates in thin films can be much different that traditionally reported corrosion rates in corresponding bulk materials. Silicon metal oxide field effect transistors (MOSFETs) built with these metals demonstrate feasibility for use in transient electronics. [ABSTRACT FROM AUTHOR]