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Cites several studies on oncology. Involvement of thrombin tumor invasion; Alignment of cyclooxygenase-2 expression with transitional cell carcinoma invasion; Contribution of mast cells to vascular remodeling in gastric adenocarcinomas.

Discusses research studies from Canada, the Republic of China and Italy concerning oncology. Involvement of thrombin in tumor invasion; Implication of the research on the field of biotechnology; Basis for the conclusion; Authors of the study; Periodical that published the research.

Details some reports from Canada, the Peoples Republic of China and Italy, which highlight recent research on oncology. Authors of the studies; Implications of the findings for oncological research; Periodical where the study was published.

Discusses an abstract of the study "Quantifying postural tremor in workers exposed to low levels of manganese" by A. Beuter and colleagues at the University of Quebec and published in the "Journal of Neuroscience Methods". Study design and methods; Continuum of changes between tremor recorded in control subjects.

The article focuses on a study, published in the 2004 issue of the journal Biochemical and Biophysical Research Communications, which states that organosulfur compounds (OSCs) in garlic may alter chemotherapeutic treatments. According to researchers, the OSCs, present in garlic, are studied for their protective effect against human cancers. P-glycoprotein and multidrug resistance protein 2 are two transporters involved in the defense of cells and in the development of multidrug resistance, in the opinion of the researchers.

Reports on the involvement of thrombin in tumor invasion based from investigators in Canada. Association of inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene with the development of vascular tumors including renal cell carcinoma; Capacity of thrombin to induce the reorganization of the cytoskeleton along with RhoA activation; Potential of thrombin to regulate VHL protein expression.

Presents a study on the involvement of thrombin in tumor invasion. Association of the inactivation of the von Hippel-Lindau tumor suppressor gene with the development of vascular tumors including renal cell carcinoma; Induction of the reorganization of the cytoskeleton along with RhoA activation; Stimulation of renal cancer cell invasion.

Discusses the abstract of "Low environmental contamination by lead in pregnant women: Effect on calcium transfer in human placental syncytiotrophoblasts," by J. LaFond and colleagues published in the 2004 issue of the "Journal of Toxicology and Environmental Health-Part A-Current Issues" periodical.

Reports on the study which demonstrated that immunization with conserved surface-accessible proteins could protect mice against pneumococcal disease. Facts about vaccine against Streptococcus pneumoniae; Indication of protective immunity against experimental sepsis and pneumonia; Implications of the study.

Presents a study on the role of Akt in regulating endometrial cancer cell survival. Detection of high levels of Akt1/2 messenger RNA and protein phosphorylation in mutated PTEN human endometrial cancer cell lines; Result of overexpressing Akt.

Discusses the abstract of a study from Quebec which revealed that male born after another male are of lower birth weight, possibly because of maternal male-related immune reaction.

Presents an abstract of the article 'HIF-1 alpha mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma,' by S. Turcotte and colleagues, published in a 2003 issue of the 'Journal of Cell Science.'

Discusses research on the influence of Rho factors on the hypoxia-related pathogenesis of renal cell carcinoma, with reference to a study led by S. Turcotte, which appeared in the 2003 issue of the "Journal of Cell Science."

The article focuses on a study, which states that thrombin is involved in tumor invasion. According to investigators in Canada, inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene is associated with the development of vascular tumors including renal cell carcinoma. Aside from the role played by the VHL protein (pVHL) in negative regulation of hypoxia-inducible factor, HIF-1alpha, pVHL also takes part in cytoskeletal organization. Thrombin is a serine protease involved in angiogenesis and in cancer progression and its action is mediated by the protease-activated receptors.

The article reports that biochemists at the University of Quebec have been testing novel estrogen-platinum(II) hybrid molecules against uterine and ovarian cancer cell lines. Researcher V. Gagnon and colleagues recently reported the synthesis of a series of original 17beta-estradiol-linked platinum(II) hybrid molecules. The biological activity of these compounds was evaluated in vitro on estrogen dependent and independent human uterine and ovarian cancers. This research was pulished in the journal "Bioorganic & Medicinal Chemistry Letters."

Reveals the finding that vascularizing tumors actively recruit bone marrow stromal progenitor cells. Discovery of the fact that bone marrow-derived stromal cells (BMSC) exhibited the ability to generate 3D capillary-like networks on Matrigel; Identification of basic fibroblast growth factor as the most potent growth factor for inducing BMSC proliferation, migration and tubulogenesis; Recruitment of BMSC when cultured in the presence of either cancerous or differentiated endothelial cell lines..

Reports on research on the impact of fibroblast growth factor and vascularizing tumors on vascular progenitors derived from murine bone marrow stromal cells (BMSC). Generation of three-dimensional capillary-like networks on Mantrigel; Inducement of BMSC proliferation; Use of in vitro co-culture assay.