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Objective: Examine the impact of COVID-19 pandemic on the outcomes in patients with CLTI or DFI. Background: Patients with CLTI and/or DFI are at risk of amputations if not treated in a timely manner. Methods: We compared the outcomes in patients with CLTI or DFI during 2 periods; Period 1[ P 1] (15/03/2019-31/05/2019) and period 2[ P 2] (15/03/ 2020-31/05/2020- corresponding to COVID-19 pandemic). Results: One hundred thirty-nine patients were treated in P1 [mean age 70 years (±11), Male:Female = 102:37] whereas 95 patients were treated in P2 [mean age 67 (±12), Male:Female = 64:31]. The 2 cohorts were matched regarding Rutherford category (P = 0.25) and GLASS classification (P = 0.38). Notably, the time from onset of symptom to clinical presentation was significantly longer [31 (1-105) days vs 27 (0–78) days, (P = 0.017)], whereas the time from presentation to first intervention was significantly shorter [3 (0–61) days vs 5 (0–65) days, (P = 0.013)] in P2 compared to P1. There was a significantly higher white cell count (P = 0.014) and CRP (P = 0.004) on admission in P2. Having treatment for CLTI or DFI in P2 was an independent predictor of worse primary patency rate and freedom from major adverse limb events. At 90 days, amputation-free survival and limb salvage were noticeably worse in P2 compared to P1 (amputation-free survival was 80% and 87% whereas limb salvage was 64% and 72% in P2 and P1, respectively). Conclusions: Patients with CLTI and DFI experienced a significantly delayed presentation with features of sepsis on admission in P2. Treatment in P2 was a predictor of worse primary patency and freedom from major adverse limb events and therefore close and long follow-up is advisable. [ABSTRACT FROM AUTHOR]

Human emotion is often a reflection of one's behaviour that leads to awareness of one's mental health. Emotion detection on Twitter users specifically gains attention as it generates information that is useful in the field of psychology and linguistics. However, most existing works related to the subject analysed the emotion of a tweet based on the number of keywords or phrases in it, thus resulting in false annotations and eventually false judgement of the user's emotion. This paper proposes a two-step model with high and reliable accuracy to detect the emotion of Twitter users based on the semantic meaning of the tweets they posted. The first step classified the emotion of each tweet using four different deep learning techniques. The second step detected the emotion of the user based on the proposed statistical post-level features and a boosting technique. Then, Kappa's agreement score method was implemented to validate both models. The first step achieved 0.9482 in accuracy while the second step achieved 0.9683 in accuracy. To further validate such highly accurate result, a case study was conducted, and a web-based system was developed to analyse the emotion of college students during the COVID-19 pandemic. Additionally, our analysis corresponded to most of the current reports on the pandemic which further proved the reliability of the developed model. [ABSTRACT FROM AUTHOR]

In this paper, longitudinal and lateral-directional aerodynamic characterisation of the Cropped Delta Reflex Wing (CDRW) configuration–based unmanned aerial vehicle is carried out by means of full-scale static wind-tunnel tests followed by full-scale flight testing. A predecided set of longitudinal and lateral/directional manoeuvres is performed to acquire the respective flight data, using a dedicated onboard flight data acquisition system. The compatibility of the acquired dynamics is quantified, in terms of scale factors and biases of the measured variables, using Kinematic consistency check. Maximum likelihood (ML), least squares and newly emerging neural Gauss–Newton (NGN) methods were implemented for a wing-alone delta configuration, mainly to capture the dynamic derivatives for both longitudinal and lateral directional cases. Estimated damping and weak dynamic derivatives, which are in general challenging to capture for a wing alone configuration, are consistent using ML and NGN methods. Validation of the estimated parameters with aerodynamic model is performed by proof-of-match exercise and are presented therein. [ABSTRACT FROM AUTHOR]

In this paper, authors have been evaluated the Frame Error Rate (FER) performance of IEEE 802.11 a/g/p standard 5 GHz frequency band WLAN over Rayleigh and Rician distributed fading channels in presence of Additive White Gaussian Noise (AWGN). Orthogonal Frequency Division Multiplexing (OFDM) based transceiver is implemented by using realtime signal processing frameworks (IEEE 802.11 Blocks) in GNU Radio Companion (GRC) and Ettus USRP N200 is used to process the symbol over the wireless radio channel. The FER is calculated for each sub-carrier conventional modulation schemes used by OFDM such as BPSK, QPSK, 16, 64-QAM with different punctuated coding rates. More precise SNR is computed by modifying the SNR calculation process of YANS and NIST error rate model to estimate more accurate FER. Here, real-time signal constellations, OFDM signal spectrums etc. are also observed to find the effect of multipath propagation of signals through flat and frequency selective fading channels. To reduce the error rate due to the multipath fading effect and Doppler shifting, channel estimation (CE) and equalization techniques such as Least Square (LS) and training based adaptive Least Mean Square (LMS) algorithm are applied in the receiver. The simulation work is practically verified at GRC by turning into a pair of Software Define Radio (SDR) as a simultaneous transceiver. [ABSTRACT FROM AUTHOR]

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Bibliometrics is most popular among the scholars, researchers and academics in the faculty of Library and Information Science research. The current study is a bibliometrics analysis of four international journals such as: 1st "Language Sciences" (LS) and 2nd "Linguistics and Education" (L&E), 3rd 'Political Geography' (PG), and 4th 'Religion' (Rgn). The present paper attempts to evaluate the publications indexed under the database of Science Direct Top 25 hottest Papers journal literature to understand the global approach of research output in four core journals. This is a comprehensive survey work rendering bibliographic records from Science Direct top 25 hottest papers database during 2005-2013, and this paper strenuously tries to give a complete sketch of the evaluation of research outputs. The key findings of the research divulge that, out of a total number of 3300 papers undertaken for the present research work, 900 were taken from 1st three journals and 600 shared by the 4th journal "Religion". It is indicated from the study that top 15 authors of all four journals identically contributed 349 (38.77%), 281 (31.22%), 384 (42.66 %) and 239 (39.83 %) papers to their credit which counts more than one third of the whole contribution except 2nd journal. In all journals the greater number 79, 76, 72, and 85 percent papers were produced by single authors, while the collaborated papers were only 21, 24, 28, and 15 percent the study unmasks. Considering the authors' institutional affiliation it is ascertained that, the authors' contributed to the journals was affiliated to 153, 152, 169 and 80 unique institutions encompassing intercontinental regions, which again determines maximum number rd of institutional contributors are involved in 3rd journal, while minimum institutional contributors in 4th journal respectively. Besides, the geographical analysis indicates the involvement of cross national regions in the research practices is well found considerably benchmarking. Moreover, the study evidently shows that the overwhelming and most productive geographical region contributors' USA shared 208 (23.11%), 354 (39.33%) and 231 (38.5 %) papers in 1st, 2nd and 4th journal with posed 1st rank, while UK achieved 1st rank having contribution 396 (44%) to the 3rd journal respectively. Resultantly, it could be professed here that, the both regions (USA and UK) are considerably granted as leading productive nations and prolific in the realm of global research. [ABSTRACT FROM AUTHOR]

This paper seeks to analyze publications indexed in the database of Science Direct Top 25 hottest Papers in Arts and Humanities journal to understand the international perspective of research publication dynamics in two core journals such as: (1st)"Language Sciences" (LS) and (2nd)"Linguistics and Education" (L&E) respectively. This is a comprehensive survey work using bibliographic records derived from Science Direct top 25 hottest papers database during 2005-2014 and this paper vigorously tries to give a complete view of the evaluation of research outcomes. Findings of the study revealed that out of a total number of 1800 papers undertaken for the present research, 50 percent were shared from each journal. It is indicated from the study that top 15 authors of 1st journal contributed 349 (38.77 %), and 2nd journal added 281 (31.22 %) papers to their credit which counts more than one third of the whole contribution. In both journals a major share 78 and 76 percent papers were produced by single authors, while the collaborated papers were only 22 and 24 percent the study discloses. Considering the authors' institutional affiliation it is ascertained that, the authors' contributed to both journals was affiliated to 153 and 152 unique institutions spread over a wide range global geographical regions. Besides, the geographical analysis claims and vitalizes the cross-national comparison in the research practices is found considerably benchmarking. The overwhelming and most productive geographical region contributor USA added 139 (15.44 %), and 220 (24.44 %) papers to both journals categorically, and maintained its status of prolificacy in the arena of global research. [ABSTRACT FROM AUTHOR]

The article presents a study on the effectiveness of different conventional methods of sire evaluation to discriminate amongst Murrah sires. Topics covered include the Network Project on Buffalo Improvement's goal to undertake progeny testing for improvement of buffalo breeds in India. Also mentioned are the best linear unbiased prediction (BLUP), simple regressed least-squares (SRLS), and contemporary comparison (CC).

Abstract: In this paper, considering the problem of low computing and low precision for the least square (LS) algorithm pilot- based in OFDM system, a novel channel estimation algorithm based on discrete Fourier transform (DFT) by transform domain, the proposed method will force time domain response value to zero beyond the length of cycle, the precision of estimation is improved, and setting threshold for time domain response within the length of the cycle to further reduce the noise on the impact of channel estimation. The proposed algorithm retains the advantages of LS algorithm, improve the accuracy of channel estimation, and simulation results show the effectiveness of algorithm. [Copyright &y& Elsevier]

Background: Recent studies suggest that ultraviolet (UV) A1 phototherapy is an effective treatment for localized scleroderma (LS); however, the optimum UVA1 dose remains to be determined. Objective: We sought to compare the immediate and long-term efficacy of low- versus medium-dose UVA1 phototherapy for plaque-type LS. Methods: Three comparable plaques in 16 patients were treated with 20 J/cm2 UVA1, 70 J/cm2 UVA1, or no irradiation. In total, 30 treatments were given. Skin thickness was determined by high-frequency ultrasound examination and clinical scoring. Assessments were done at baseline, immediately after treatment, and 3, 6, and 12 months thereafter. Results: Ultrasound measurement showed a significantly greater reduction of skin thickness with 70 J/cm2 than with 20 J/cm2 at all time points of the study except immediately after UVA1 treatment. The clinical score of the irradiated plaques also decreased substantially but failed to detect a significant difference between the two dose regimens. Limitations: Our results only pertain to plaque-type LS and are limited by a small sample size. Conclusion: Medium-dose provides for better long-term results than low-dose UVA1 in LS as shown by ultrasound assessment. With clinical scoring, no significant difference between the two UVA1 dose regimens was detected, indicating that ultrasound measurement is a more sensitive method for quantifying treatment-induced skin changes in patients with LS. [Copyright &y& Elsevier]

Summary Introduction Over 27,000 circumcisions were performed in England in 2012–13. The complication rate is generally perceived to be low, although published figures vary widely. Balanitis xerotica obliterans, more correctly termed Lichen Sclerosus et atrophicus (LS), is one of the commonest indications for medical circumcision. To test the hypothesis that children undergoing circumcision for LS have a higher rate of postoperative bleeding than those undergoing the procedure for other reasons, we retrospectively reviewed records for patients undergoing circumcision. Methods The disease and procedure coding system was used to identify patients who underwent circumcision (ICD10 code N303) between 2000–2010. Cases with a diagnosis unrelated to circumcision and children circumcised during hypospadias repair were excluded. Bleeding which required return to theatre for surgical arrest was considered significant. Cases were identified by review of medical records if there was: a second procedure during the same admission, or readmission coded for circumcision within 2 weeks. Only cases with histologically confirmed LS were included in the LS cohort. GraphPad online calculator was used for statistical analysis (two tailed Fisher's exact test. Results 2385 boys with a median age of 4 years (range 0–16) were included in the study. Indication for circumcision included religious (1305, 54.7%), phimosis or redundant prepuce (512, 21.5%), suspected LS (366, 15.4%) and balanoposthitis (202, 8.5%). LS was histologically confirmed in 262 (10.9%) boys. Fourteen (0.6%) patients returned to theatre for surgical arrest of bleeding following circumcision; 6 had LS and 8 did not (Table 1). The bleeding rate was higher in those with LS (2.3%) than in those without (0.3%), P = 0.0003 with a relative risk of 6.08. Conclusion Post-operative complications are distressing, especially if further surgery is required. Published figures for complications following circumcision vary widely making counseling regarding risk difficult. Since LS includes an inflammatory element and circumcision in widespread LS can be challenging, the observation of more post-operative bleeding in patients with histologically confirmed LS during a previous audit prompted the hypothesis that this may be a significant finding. Thus we reviewed all patients requiring return to theatre within 2 weeks of circumcision, finding that whilst the overall bleeding rate was low, circumcision for LS significantly increased the risk. Although factors such as the severity of LS and surgical technique were not assessed, this is still a notable finding which should be reflected during pre-operative counseling. Table Patients requiring return to theatre for surgical arrest of bleeding. Table Postoperative diagnosis Number of patients Number returning to theatre Religious preference 1305 3 Phimosis or redundant prepuce 499 3 Balanoposthitits 200 2 Confirmed lichen sclerosus 262 6 Suspected but unconfirmed lichen sclerosus 119 0 Total 2385 14 [ABSTRACT FROM AUTHOR]