256 results on '"Alhaj A"'
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2. A Cross-Sectional Cone-Beam Computed Tomography Study of Root Canal Morphology and Configuration of Mandibular Premolars in Saudi and Sudanese Subpopulations
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Salah, Lina, Alkhames, Hussain M., Alhaj, Zokaa, Al-Jubran, Saleh M. A., Mohammed, Aseel, Baleis, Hussain H. I., Almadeh, Naji M. M., and Ibrahim, Amir I. O.
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- 2024
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3. Ultrasound‐Guided Vs Non‐Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. A Randomized Clinical Trial
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Alhaj Kheder, Mohammad Badr, Kandil, Nour Mohamed, El‐Ghareeb, Tarek, Abdel Aziz, Omniya Mohamed, and Zeitoun, Rania
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This randomized clinical trial study aims to compare ultrasound‐guided versus non‐guided Dextrose 10% injections in patients suffering from internal derangement in the temporomandibular joint (TMJ). The study population included 22 patients and 43 TMJs suffering from unilateral or bilateral TMJ painful clicking, magnetic resonance imaging (MRI) proved disc displacement with reduction (DDWR), refractory to or failed conservative treatment. The patients were divided randomly into two groups (non‐guided and ultrasound (US)‐guided groups). The procedure involved injection of 2 mL solution of a mixture of 0.75 mL 0.9% normal saline solution, 0.3 mL 2% lidocaine and 0.75 mL dextrose 10% using a 25G needle in the joint and 1 mL intramuscular injection to the masseter muscle at the most tender point. The Visual Analogue Score (VAS) was used to compare joint pain intensity over four different periods, beginning with pre‐injection, 1‐, 2‐, and 6‐months postinjection. Twenty‐two patients 5 males (n = 5/22, 22.7%) and 17 females (n = 17/22, 77.2%) were included in this study. The mean age was 27.3 ± 7.4 years (30.2 ± 7.0) for the non‐guided group and 24.3 ± 6.9 for the US‐guided group. The dextrose injection reduced intensity over time in both groups with statistically significant improvement (Pvalue <.05) at 2 and 6 months in both groups. There was no statistically significant difference in VAS assessment between both groups. Intra‐articular injection of dextrose 10% for patients with painful clicking and DDWR resulted in reduced pain intensity in both US‐guided and non‐guided groups with significant symptomatic improvement over time in both groups. US guidance allowed accurate anatomical localization and safe procedure with a single joint puncture.
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- 2024
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4. Chimeric antigen receptor T-cell infusion for large B-cell lymphoma in complete remission: a center for international blood and marrow transplant research analysis
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Wang, Trent P., Ahn, Kwang W., Shadman, Mazyar, Kaur, Manmeet, Ahmed, Nausheen, Bacher, Ulrike, Cerny, Jan, Chen, Andy, Epperla, Narendranath, Frigault, Matthew, Grover, Natalie, Haverkos, Bradley, Hill, Brian, Hossain, Nasheed, Iqbal, Madiha, Jain, Tania, Krem, Maxwell M., Maakaron, Joseph, Modi, Dipenkumar, Alhaj Moustafa, Muhamad, Riedell, Peter, Savani, Bipin, Sica, R. Alejandro, Sureda, Anna, Wudhikarn, Kitsada, Herrera, Alex F., Sauter, Craig, Hamadani, Mehdi, and Jimenez Jimenez, Antonio
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CD19 CAR T-cell (CAR-T) therapy is commonly administered to patients with relapsed or refractory large B-cell lymphomas (LBCL), but salvage or bridging therapy can sometimes lead to a complete response (CR) prior to infusion. Limited studies have assessed the outcomes of patients infused in CR. A total of 134 patients with LBCL in CR prior to CAR-T infusion were identified from the CIBMTR registry, with median prior lines of therapy of 3 (range 2–9). At two years post-infusion, the probability of progression-free survival was 43.5% (95% CI 34.4–52.8) and the probability of overall survival was 63.8% (95% CI 54.4–72.6). The cumulative incidence rates of non-relapse mortality and relapse/progression at two years were 9.2% (95% CI 4.5–15.4) and 47.3% (95% CI 38.2–56.6), respectively. The rate of grade 3 or higher cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) were 2.2% and 8.2%, respectively. In summary, CAR-T in heavily pretreated patients with LBCL who are in CR following two or more lines of prior therapy demonstrate that a subset of patients may remain free of progression at two years. Additionally, the toxicity profile was impressive with very low rates of grade 3 CRS and ICANS.
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- 2024
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5. A US Multicenter Collaborative Study on Outcomes of Hematopoietic Cell Transplantation in Hepatosplenic T-Cell Lymphoma
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Moustafa, Muhamad Alhaj, Ramdial, Jeremy L., Tsalatsanis, Athanasios, Khimani, Farhad, Dholaria, Bhagirathbhai, Bojanini, Leyla, Brooks, Taylor Rey, Zain, Jasmine, Bennani, N. Nora, Braunstein, Zachary, Brammer, Jonathan E., Beitinjaneh, Amer, Jagadeesh, Deepa, Weng, Wen Kai, Kumar, Ambuj, Kharfan-Dabaja, Mohamed A., Ahmed, Sairah, and Murthy, Hemant S.
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•Autologous and allogeneic hematopoietic cell transplantation are both effective consolidative strategies in patients with Hepatosplenic T Cell Lymphoma.•Median overall survival and progression free survival for the entire cohort were 78.5 months (95% CI: 25-NR) and 54 months (95% CI: 18 to 75), respectively.•No significant differences in OS or PFS we seen when comparing autologous and allogeneic HCT groups.•Pts with less than CR at time of transplant had better median overall survival with allogeneic hematopoietic cell transplantation compared to autologous hematopoietic cell transplantation (65 mo versus 7 mo, P< .001).
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- 2024
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6. Design and analysis of a robust security layer for software defined network framework
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Alhaj, Ali Nadim, Patel, Narottam Das, Singh, Ajeet, Bondugula, Rohit Kumar, Dar, Mohsin Furkh, and Ahamed, Jameel
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The rapid expansion of networks has given rise to numerous challenges and issues. In recent years, one idea that has captivated researchers is segregating the forwarding and control levels, which emerged with software-defined networking (SDN) frameworks. Despite centralised management and network administration advantages, SDN networks have encountered several issues, with safety and reliability being the most prominent. This paper proposes a comprehensive robust security architecture for SDN networks that consists of modular components. Each module addresses a specific security challenge, and by integrating these security solutions, we aim to establish a cohesive security framework for SDN. Furthermore, we propose a robust security algorithm capable of effectively mitigating critical security attacks such as DDoS, ARP, and MITM. Our approach involves developing a multi-level security algorithm to counteract most DDoS attacks, while also devising a real-time algorithm specifically designed to handle ARP attacks, including request-replay-ARP DoS attacks.
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- 2024
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7. A comparison between robotic-assisted and open approaches for large ventral hernia repair—a multicenter analysis of 30 days outcomes using the ACHQC database
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Lima, Diego L., Nogueira, Raquel, Ma, Jianing, Jalloh, Mohamad, Keisling, Shannon, Saleh, Adel Alhaj, and Sreeramoju, Prashanth
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Introduction: Over the last few decades, there has been an increase in the use of a minimally invasive (MIS) approach for complex hernias involving component separation. A robotic platform provides better visualization and mobilization of tissues for component separation. We aim to assess the outcomes of open and robotic-assisted approaches for large VHR utilizing the ACHQC national database. Methods: A retrospective review of prospectively collected data from the Abdominal Core Health Quality Collaborative (ACHQC) was performed to include all adult patients who had primary and incisional midline ventral hernias larger than 10 cm and underwent elective open and robotic hernia repairs with mesh from January 2013 to March 2023. Univariate and multivariate analyses were performed comparing Open and Robotic approaches. Results: The ACHQC database identified 5,516 patients with midline hernias larger than 10 cm who underwent VHR. The open group (OG) had 4,978 patients, and the robotic group (RG) had 538. The RG had a higher median BMI (33.3 kg/m
2 (IQR 29.8–38.1) vs 32.7 (IQR 28.7–36.6) (p< 0.001). Median hernia width was 15 cm (IQR 12–18) in the OG and 12 cm in the RG (10–14) (p < 0.001). Sublay positioning of the mesh was the most common. The fascial closure was higher in the RG (524; 97% versus 4,708; 95%—p= 0.005). Median Length of Stay (LOS) was 5 days (IQR 4–7) in the OG and 2 days (IQR 1–3) in the RG (p < 0.001). The readmission rate was higher in the OG (n= 374; 7.5% vs n= 16; 3%; p < 0.001). 30-day SSI were higher in the OG (343; 6.9%% vs 14; 2.6%; p < 0.001). Logistic regression analysis identified diabetes (OR 1.6; CI 1.1–2.1; p= 0.006) and BMI (OR 1.04, CI 1.02–1.06; p < 0.001) as predictors of SSIs, while the robotic approach was protective (OR 0.35, CI 0.17–0.64; p= 0.002). For SSO, logistic regression showed BMI (OR 1.04, CI 1.03–1.06; p < 0.001) and smoking (OR 1.8, CI 1.3–2.4; p < 0.001) as predictors Robotic approach was associated with lower readmission rates (OR .04, CI 0.2–0.6; p < 0.001). Conclusion: A robotic approach improves early 30-day outcomes compared to an open technique for large VHR. There was no difference in SSO at 30 days.- Published
- 2024
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8. Millimeter Wave Indoor SAR Sensing Assisted With Chipless Tags-Based Self-Localization System: Experimental Evaluation
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Batra, Aman, Abbas, Ali Alhaj, Sanchez-Pastor, Jesus, El-Absi, Mohammed, Jimenez-Saez, Alejandro, Khaliel, Maher, Barowski, Jan, Wiemeler, Michael, Gohringer, Diana, Rolfes, Ilona, Jakoby, Rolf, and Kaiser, Thomas
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This article addresses indoor environment mapping by employing the synthetic aperture radar (SAR) technique at millimeter wave (mmWave) frequencies. The mmWave-based SAR can provide a high-resolution map, for example, of an emergency scenario like a burning room. The high-resolution map drives a new era of SAR applications such as object detection, classification, characterization, and precise localization. A major requirement at high frequencies is the precise knowledge of SAR trajectory, where radar sensors are mounted on a mobile platform such as a drone or unmanned aerial vehicle (UAV). State-of-the-art localization methods such as global positioning system (GPS)-aided inertial measurement units (IMUs) are not valid due to limited coverage and accuracy. One of the primary solutions could be the SAR assisted with an indoor localization system, which is exploited in the work. The presented indoor localization system comprises two types of passive chipless frequency-coded tags, based on dielectric resonators (DRs) and frequency-selective surfaces. In this work, first, the proposed method of integrating SAR and localization systems is evaluated in a single-tag environment. Further, a version of a room equipped with a multitag system is considered for real-time applications, and a successful demonstration of indoor environment mapping for the frequency spectrum of 75–110 GHz is presented.
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- 2024
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9. Energy Drinks Consumption, Knowledge and Self-Reported Effect among University Students in Jordan: Cross-sectional Study
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Elsahoury, Nour Amin, Alhaj, Omar A., McGrattan, Andrea M., and Hammad, Fwziah J.
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Background: Consumption of energy drinks (EDs) has increased exponentially among younger generations, and this increase is projected to continue.Objectives: This study aimed to examine the prevalence, knowledge level, intake patterns, and consumer experience of consuming EDs among university students in Jordan.Methods: A cross-sectional study of 467 students from 29 universities was conducted by a webbased questionnaire. Descriptive analyses, chi-square tests, and logistic regression were performed, with a p-value of ≤0.05 indicating significance.Results: The prevalence of EDs was 40.1% among university students. Over half (62.7%) of students had poor knowledge of EDs. The most significant determinants identified were male (OR=2.18; 95%CI: 1.14-4.15), undergraduate (OR: 4.01; 95% CI: 1.70-9.72), in a nonmedical discipline (OR=2.92; 95% CI: 1.56-5.44), smoker (OR=9.91;95%Cl: 5.30-18.54) and having a poor knowledge level (OR=40.46;95%CI: 14.33-114.27). Students mainly consumed Red Bull, and the majority consumed 1-2 can(s) daily. Students were more likely to consume EDs during exams to mainly stay awake. The major side effects experienced by this sample were increased urination and headache. No changes in mental or physical performance, weight, appetite, and sleeping pattern were observed among the majority of respondents.Conclusion: Consumption of EDs was moderate among university students. Gender, study course, study year, smoking, and knowledge level were determinants of their intake.
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- 2024
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10. Stereochemistry Determines Immune Cellular Responses to Polylactide Implants.
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Maduka, Chima V., Alhaj, Mohammed, Ural, Evran, Kuhnert, Maxwell M., Habeeb, Oluwatosin M., Schilmiller, Anthony L., Hankenson, Kurt D., Goodman, Stuart B., Narayan, Ramani, and Contag, Christopher H.
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- 2023
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11. Construction of a Zinc Oxide Nanorod-Modified Coated Wire Electrode for Potentiometric Determination of Levocetirizine Dihydrochloride in Its Pure and Combined Form
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Nashed, Dania, Noureldin, Imad, and Alhaj Sakur, Amir
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- 2023
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12. Autoencoders with deformable convolutions for latent representation of EEG spectrograms in classification tasks
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Osten, Wolfgang, Nikolaev, Dmitry P., Zhou, Jianhong (Jessica), Zubrikhina, Maria, Masnyi, Dmitrii, Hamoudi, Rifat, Alhaj, Hamid, Issa, Bashar, Kustubaeva, Almira, Kamzanova, Altyngul, Zholdassova, Manzura, Bernstein, Alexander, Burnaev, Evgeny, Artemov, Alexey, and Sharaev, Maxim
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- 2023
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13. The impact of a social-media-based weight management program: insights from the community campaign “obesity does not suit me”
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Alsaad, Areej, Aleid, Kawthar, Almadani, Layla, Alhaj, Omar, Jahrami, Haitham, and Janahi, Abdulrahman
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Purpose: This study aimed to assess the influence of the community-based campaign on weight loss and healthy lifestyle adoption among Bahrain's adult population. Design/methodology/approach: A cross -sectional self-reported online questionnaire completed in February 2021. The survey evaluated the impact of the community-based campaign health program which includes (exercise, diet plan and psychological eating behavior) weight reduction using social media platforms. The authors employed data from young and middle-aged healthy adults (n = 842) between the ages of 18-55 years, of both sexes. The intervention group (n = 842) was made up of the supporters of the voluntary community initiative called Obesity does not Suit Me (n = 194), and the control group (n = 648) was made up of non-followers of the campaign. Findings: The study showed a statistically significant difference among the followers of the community-based campaign health program in the following parameters: 3.90-4.23 kg less, 1.46-1.59 difference in BMI and 0.05-0.06 WHR. All changes were of low effect size. Originality/value: Diet and exercise had significant impact on weight, BMI and WHR among the followers of the community campaign. However, more research is required for sponsorship to increase the motivation and rewards for the community campaign.
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- 2023
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14. Improved Outcomes in Treating Acute Biliary Disorders With a Shift-Based Acute Care Surgery Model
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McGill, Michelle, Dhanasekara, Chathurika S., Caballero, Beatrice, Chung, Caroline, Alhaj-Saleh, Adel, Santos, Ariel, Ronaghan, Catherine, Dissanaike, Sharmila, and Richmond, Robyn
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Background As Acute Care Surgery and shift-based models increase in popularity, there is evidence of better outcomes for many types of emergency general surgery patients. We explored the difference in outcomes for patients with acute biliary disorders, treated by either Acute Care Surgery (ACS) model or traditional call model (TRAD) during the same period.Methods Retrospective review of patients undergoing laparoscopic cholecystectomy for acute biliary disease 2017-2018. Demographics, clinical presentation, operative details, and outcomes were compared.Results Demographics, clinical presentation, and complication rates were similar between groups. Time from surgical consult to operating room (Δ = −15.34 hours [−24.57, −6.12], P= .001), length of stay (Δ = −1.4 days [−2.45, −.35], P= .009), and total charges were significantly decreased in ACS group compared to TRAD (Δ$2797.76 [−4883.12, −712.41], P= .009).Conclusions Acute biliary disease can be managed successfully in an ACS shift-based model with reduced overall hospital charges and equivalent outcomes.
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- 2023
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15. THE SAFETY OF SPHINCTEROTOMY IN ERCP AMONG PATIENTS WITH CIRRHOSIS: INSIGHTS FROM A QUATERNARY CARE TRANSPLANT CENTER.
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Nimri, Faisal, Jamali, Taher, Ali, Suhib Alhaj, Dawod, Sanad, Alluri, Spandana, Youssef, Rami, Faisal, Muhammad Saad, Omeish, Haya, Abusuliman, Muhammad, Saleem, Abdulmalik, Alomari, Ahmad, Faisal, Muhammad Salman, Singla, Sumit, and Zuchelli, Tobias
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- 2024
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16. ASSESSING PROCEDURE OUTCOMES FOLLOWING PIECEMEAL COLD SNARE ENDOSCOPIC MUCOSAL RESECTION OF LARGE NON-PEDUNCULATED COLORECTAL POLYPS.
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Shamaa, Omar, Ali, Suhib Alhaj, Omeish, Haya, Alomari, Ahmad, Dababneh, Yara, Piraka, Cyrus, and Zuchelli, Tobias
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- 2024
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17. ASSESSING PROCEDURE OUTCOMES FOLLOWING PIECEMEAL COLD SNARE ENDOSCOPIC MUCOSAL RESECTION OF LARGE NON-PEDUNCULATED COLORECTAL POLYPS.
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Shamaa, Omar, Ali, Suhib Alhaj, Omeish, Haya, Alomari, Ahmad, Dababneh, Yara, Piraka, Cyrus, and Zuchelli, Tobias
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- 2024
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18. Learning from Errors High-Fidelity Simulation: Innovative Teaching Strategy for Next Generation NCLEX.
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Musallam, Eyad and Ali, Abeer Alhaj
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The article focuses on innovative teaching methods to enhance nursing students' clinical judgment skills, critical thinking, and decision-making in preparation for the Next Generation NCLEX (NGN). It describes a Learning from Errors High-Fidelity Simulation (LEHFS) approach that involves creating intentional errors within clinical scenarios presented through videos, allowing students to recognize errors and propose corrective actions with rationales.
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- 2024
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19. The impact of Ramadan fasting on the metabolic syndrome severity in relation to ethnicity and sex: Results of a systematic review and meta-analysis.
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Jahrami, Haitham, Trabelsi, Khaled, Alhaj, Omar A., Saif, Zahra, Pandi-Perumal, Seithikurippu R., and BaHammam, Ahmed S.
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Aims: The primary goal of this meta-analysis was to examine the changes in various components of metabolic syndrome (MetS) in healthy adults who observed Ramadan fasting (RF) before Ramadan (T1) and at the end of RF (T2). A secondary goal was to assess the impact of RF on MetS severity in various ethnic and sex groups using the MetS z-score.Data Synthesis: Using PRISMA2020, seven databases were searched for relevant studies published between January 1950 and March 2022. Data extraction involved high-density lipoprotein cholesterol (HDL), triglycerides (TG), fasting blood glucose (FBG), waist circumference (WC), systolic blood pressure (SBP), and diastolic blood pressure (DBP) for T1 and T2, respectively. The MetS z-score was computed according to international diabetes federation criteria. At T1, the pooled estimates of HDL, TG, FBG, WC, SBP, DBP, and MAP were 1.20 [1.13; 1.27] mmol/L, 1.32 [1.23; 1.42] mmol/L, 4.98 [4.82; 5.15] mmol/L, 87.21 [84.21; 90.21] Cm, 114.22 [101.45; 126.99] mmHg, 76.80 [70.12; 83.47] mmHg, and 89.27 [80.56; 97.98] mmHg, respectively. At T2, the pooled estimates of HDL, TG, FBG, WC, SBP, DBP, and MAP were 1.24 [1.18; 1.31] mmol/L, 1.24 [1.14; 1.34] mmol/L, 4.77 [4.55; 4.99] mmol/L, 85.73 [82.83; 88.64] Cm, 109.48 [97.20; 121.75] mmHg, 74.43 [68.01; 80.85] mmHg, and 86.11 [77.74; 94.48] mmHg, respectively. The MetS z-score showed improvement at T2 for all ethnic groups and both sexes by -0.22 [-0.24; -0.01].Conclusions: The current meta-analysis suggests that the RF positively impact the MetS components and the overall MetS z-score.Prospero Registration Number: ID CRD42022329297 OPEN SCIENCE FRAMEWORK IDENTIFIER: DOI 10.17605/OSF.IO/U9H7T. [ABSTRACT FROM AUTHOR]- Published
- 2022
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20. Improving mechanical properties of oil well cement using polypropylene fibers and evaluating a new laboratory method for measuring the casing cement bonding strength.
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Al Khalaf, Hani, Kovacsne, Gabriella Federer, Mohammed, Nagham Alhaj, and Remeczki, Ferenc
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POLYPROPYLENE fibers ,OIL well cementing ,BOND strengths ,FIBERS ,CEMENT ,INTERFACIAL bonding ,FLEXURAL strength - Abstract
Copyright of Rudarsko-Geolosko-Naftni Zbornik is the property of Faculty of Mining, Geology & Petroleum Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2022
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21. Blunt injury to the right hepatic duct: A rare case report.
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Al-Jawad, Mohammad, Tijan, Nawal, Kawas, Abdulmonem, Lbabidi, Nour Abdulazize, Sheikh, Alan, and Alhaj, Ahmad
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Extrahepatic bile duct injuries can occur after abdominal trauma, though more commonly they are iatrogenic. Definitive surgical repair is the mainstay of treatment but has a significant incidence of complications, particularly when managed by non-specialist surgeons or with delayed referral to a specialized center. A 17-year-old male presented with a blunt abdominal injury after a fall, resulting in a right hepatic duct injury that was managed with a Roux-en-Y hepaticojejunostomy. Despite the initial surgical repair, the patient developed a bile leak and fluid collections, requiring a second laparotomy for drainage and lavage, with a favorable outcome at a 6-month follow-up. Traumatic extrahepatic biliary injuries, though uncommon, can have variable etiologies, with blunt trauma being more prevalent in the pediatric population and associated with higher mortality. In the current case, prompt diagnosis and surgical management with a Roux-en-Y hepaticojejunostomy led to a favorable outcome for the patient presenting with a right hepatic duct injury. Injuries to the common hepatic duct are uncommon, but the potential for concomitant injuries to the right or left hepatic ducts should be carefully considered when determining the appropriate surgical management for complex extrahepatic biliary tract trauma. • Extrahepatic bile duct injuries are commonly iatrogenic, typically from cholecystectomy, but can also occur from trauma. • Definitive surgical repair is the main approach for bile duct injuries (BDI) and biliary strictures, with stricture rates of 10% to 20% even in high-volume centers. • In this case, the injury was managed with Roux-en-Y anastomosis, including cholecystectomy and anastomosis between the bile duct and small intestine. [ABSTRACT FROM AUTHOR]
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- 2024
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22. Thoracobilliary fistula as a rare complication of Roux-en-Y cholangio-jejunostomy stricture after iatrogenic bile duct injury correction: A case report.
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Alhamedh, Alhussein, Aldaher, Mohammad, Toutounji, Rahaf, Alhussein, M.Wafa Hamoud, Aswad, Ali, and Moustafa, Kadri Alhaj
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Thoracobiliary fistula is a rare presentation of biliary obstruction which is secondary to anastomotic Roux-en-Y cholangiojejunostomy stricture. A 52-year-old man presented with fever, fatigue, and anorexia. He was jaundiced. He had a history of a laparoscopic cholecystectomy complicated by iatrogenic bile duct injury which was corrected by Roux-en-Y cholangiojejunostomy. The CT revealed a subphrenic abscess. Therefore, we established CT-directed percutaneous drainage and antibiotics treatment. Four months later, he presented again with fever, fatigue, and jaundice. He also complained of bilioptysis. Pleurocentesis revealed a deep yellow pleural fluid. Thoracobiliary fistula was suspected. Our patient underwent a right thoracotomy where we drained bile, performed pleural decortication, and excised the damaged portion of the right lower pulmonary lobe. We also inserted a subphrenic drain. The fistula was remained to close spontaneously and the patient had a good postoperative recovery. The obstruction of the bile ducts leads to the retention of bile proximal to the obstruction site, the formation of a liver biloma, and subsequently the abscess formation. By increasing, the abscess gradually erodes the diaphragm. A presence of adhesions between the lower lung lobe and the diaphragm will lead the abscess to erode directly into the lung parenchyma until it reaches the nearest bronchus and a BBF is formed. The presence of bile in the pleural space due to pleurobiliary fistula, or bilioptysis due to bronchobiliary fistula are rare presentations. However, they are serious conditions that may follow bile duct operations. They require early recognition and intervention. • Pleurobiliary fistula is a very rare presentation of common bile duct obstruction. • Thoracobiliary fistula is a serious condition that may follow bile duct operations. • bronchobiliary fistula is usually diagnosed clinically by bilioptysis. • Thoracobiliary fistula treatment is surgical, conservative, or a combination of both. [ABSTRACT FROM AUTHOR]
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- 2024
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23. Stereochemistry Determines Immune Cellular Responses to Polylactide Implants
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Maduka, Chima V., Alhaj, Mohammed, Ural, Evran, Kuhnert, Maxwell M., Habeeb, Oluwatosin M., Schilmiller, Anthony L., Hankenson, Kurt D., Goodman, Stuart B., Narayan, Ramani, and Contag, Christopher H.
- Abstract
Repeating l- and d-chiral configurations determine polylactide (PLA) stereochemistry, which affects its thermal and physicochemical properties, including degradation profiles. Clinically, degradation of implanted PLA biomaterials promotes prolonged inflammation and excessive fibrosis, but the role of PLA stereochemistry is unclear. Additionally, although PLA of varied stereochemistries causes differential immune responses in vivo, this observation has yet to be effectively modeled in vitro. A bioenergetic model was applied to study immune cellular responses to PLA containing >99% l-lactide (PLLA), >99% d-lactide (PDLA), and a 50/50 melt-blend of PLLA and PDLA (stereocomplex PLA). Stereocomplex PLA breakdown products increased IL-1β, TNF-α, and IL-6 protein levels but not MCP-1. Expression of these proinflammatory cytokines is mechanistically driven by increases in glycolysis in primary macrophages. In contrast, PLLA and PDLA degradation products selectively increase MCP-1 protein expression. Although both oxidative phosphorylation and glycolysis are increased with PDLA, only oxidative phosphorylation is increased with PLLA. For each biomaterial, glycolytic inhibition reduces proinflammatory cytokines and markedly increases anti-inflammatory (IL-10) protein levels; differential metabolic changes in fibroblasts were observed. These findings provide mechanistic explanations for the diverse immune responses to PLA of different stereochemistries and underscore the pivotal role of immunometabolism in the biocompatibility of biomaterials applied in medicine.
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- 2023
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24. Wheat Straw Burial Improves Physiological Traits, Yield and Grain Quality of Rice by Regulating Antioxidant System and Nitrogen Assimilation Enzymes under Alternate Wetting and Drying Irrigation.
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Hamoud, Yousef Alhaj, Shaghaleh, Hiba, Wang, Ruke, Gouertoumbo, Willy Franz, Hamad, Amar Ali Adam, Sheteiwy, Mohamed Salah, Wang, Zhenchang, and Xiangping, Guo
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WHEAT straw ,RICE quality ,GRAIN yields ,BROWN rice ,NITRATE reductase ,GLUTAMINE synthetase ,SOIL ripping - Abstract
Wheat straw burial has great potential to sustain rice production under alternate wetting and drying (AWD) irrigation. A field experiment was conducted with three wheat straw burial treatments, including without straw burial (NSB), with light straw burial of 300 kg/hm
2 (LSB) and dense straw burial of 800 kg/hm2 (DSB), as well as three AWD regimes: alternate wetting/moderate drying (AWMD), alternate wetting/severe drying (AWSD) and alternate wetting/critical drying (AWCD). The rice growth and grain quality were higher in LSB and NSB than those in NSB under the same AWD regime. The AWMD × DSB treatment resulted in the highest yield, brown rice rate, milled rice rate, amylose content and protein content. Conversely, the AWCD × NSB treatment led to the lowest yield, brown rice rate, milled rice rate, amylose content and protein content. The active absorption area and nitrate reductase activity of roots were higher in the AWMD × DSB treatment than those in the AWCD × NSB treatment, as the former increased organic carbon and nitrogen contents in the rhizosphere, whereas the latter reduced their availability. Total soluble protein content and glutamine synthetase activity were greater in the AWMD × DSB treatment than those in the AWCD × NSB treatment. The activities of superoxide dismutase and catalase were higher in the AWMD × DSB treatment compared with the AWCD × NSB treatment, leading to the amelioration of oxidative cell injury, as shown by a lower malonaldehyde level. This study suggested that farmers should implement AWMD irrigation after leaving the straw residues in the field, followed by deep tillage to improve soil quality and mitigate the drought stress cycles of AWD. This approach can improve rice growth and grain quality and alleviate the problems of disposal of straw residues and water scarcity for sustainable rice production. [ABSTRACT FROM AUTHOR]- Published
- 2022
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25. First report of the mobile colistin resistance gene, mcr-1.26, in multidrug-resistant Escherichia coliisolated from retail chicken meat
- Author
-
Kassem, Issmat I., Osman, Marwan, Hassan, Jouman, Sulaiman, Abdallah Alhaj, Mann, David, Esseili, Malak A., Naas, Thierry, and Deng, Xiangyu
- Abstract
We isolated a highly colistin-resistant Escherichia coli, strain 58, from fresh chicken wings in Lebanon. Here, we performed in-depth phenotypic and genomic analyses to identify the resistome of the isolate, focusing on the determinants that encoded colistin resistance.
- Published
- 2023
- Full Text
- View/download PDF
26. Intellectual Rights in the Light of the Qurʾan and Universal Declaration of Human Rights
- Author
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Abu Alhaj, Thabet Ahmad Abdallah
- Published
- 2023
- Full Text
- View/download PDF
27. Selection of most relevant input parameters for predicting photovoltaic output power using machine learning and quadratic models
- Author
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Kassem, Youssef and Othman, Adnan Alhaj
- Abstract
Predicting the photovoltaic (PV) output power is essential for the power grid's secure, stable, and economical operation. Additionally, there are large numbers of meteorological variables that potentially affect the solar output of PV panels. Hence, identifying the most relevant parameters that influenced the PV output power is necessary for achieving accurate predictions and reducing the time-consuming and costly to acquire these parameters. With this main objective, four artificial intelligence techniques [Multilayer Feed-Forward Neural Network (MFFNN), Cascade Feed-forward Neural Network (CFNN), Radial Basis Function Neural Network (RBFNN), and Elman neural network (ENN)] were employed to identify the most influencing input parameters for prediction of the energy output of PV system. To develop the models, the mean daily average temperature, minimum and maximum temperatures, wet-bulb temperature, relative humidity, global solar radiation, and wind speed were used as potential inputs to solar output prediction models. The data set covers 12 operating months (01 January–31 December 2020). 57 models with various combinations of inputs were proposed and used to train the models to find the combination of inputs to determine the mean daily energy output of the PV system. The reliability of utilized models was examined by correlation coefficient (R), mean absolute error (MAE), and root mean square error (RMSE). The results indicate that MFFNN#19, CFNN#12, ENN#24, and RBFNN#32 with the combination of [Tmax, RH], [Ta, GSR], [Tw, GSR] and [D, Tmin], respectively, are the best models for solar output of the system. Moreover, a comparison of the performances of the artificial intelligence techniques with the quadratic model and multiple linear regression has been reported in this study. The results demonstrate that the ENN#24 model with the combination of [Tw, GSR] generated superior results than the other models in terms of the R-squared, RMSE, and MAE, showing the ability of the model to estimate the PV output power.
- Published
- 2022
- Full Text
- View/download PDF
28. The Effectiveness of Monetary Policy in Jordan during the Period 1992-2019.
- Author
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Fseifes, Eman Abdel Khalek and Yousef, Elham Mohammad Alhaj
- Published
- 2022
- Full Text
- View/download PDF
29. Crawler and Its Linguistic Challenges in the Arabic Language Sites A Case study of Syrian Newspapers.
- Author
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Badran, Asmaa Alhaj
- Subjects
ARABIC language ,SYRIAN newspapers ,SEARCH engines ,ORAL communication ,METHODOLOGY - Abstract
Crawler, a Web indexing program or an Internet robot/bot (Spetka, 2004), is a software application that runs automated scripts over the Internet. The Web engines use it to update the content and sites via copying all the accessed pages and processing them into indexes so that the users can search much more sufficiently. Crawling is the first stage that downloads Web documents, which the indexer indexes for later use by searching module, with feedback from other backgrounds. This module could also provide on-demand crawling services for search engines. Yet, with the massive amount of data that has been fed on the web, we still encounter some problems and challenges while crawling data. Subsequently, through the wide-open access to all search engines, Arabic content is hitherto scantily accessible. This paper descriptively details the stances and challenges that the Arabic language, the fifth most spoken language, might grapple with while crawling data. [ABSTRACT FROM AUTHOR]
- Published
- 2022
30. Improvised beach hut provides measure of comfort and joy.
- Author
-
Ali, Eman Alhaj
- Abstract
Oppressive heat drove Motaz Barzaq to the beach to construct a home like no other. [ABSTRACT FROM AUTHOR]
- Published
- 2024
31. 534 Mycosis fungoides and sezary syndrome in African American and Hispanic patients: A matched case-control study
- Author
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Martinez, C., Hwang, A., Kechter, J., Nassir, S., Yousif, M., Ogbaudu, E., Butterfield, D., Comfere, N., Sluzevich, J., Sokumbi, O., Moustafa, M. Alhaj, Bennani, N., Foran, J., Pittelkow, M., DiCaudo, D., Rule, W., Rosenthal, A., and Mangold, A.R.
- Published
- 2024
- Full Text
- View/download PDF
32. Effective and green in-situ remediation strategies based on TEMPO-nanocellulose/lignin/MIL-100(Fe) hydrogel nanocomposite adsorbent for lead and copper in agricultural soils.
- Author
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Shaghaleh, Hiba, Alhaj Hamoud, Yousef, and Sun, Qin
- Subjects
SOIL washing ,WHEAT ,COPPER ,COPPER in soils ,SOIL pollution ,WATER purification - Abstract
Hydrogel adsorbents are promising tools for reducing heavy metals' bioavailability in contaminated soil. However, their practical feasibility remains limited by the low stability, inefficient removal efficiency, and potential secondary pollution. Optimizing the adsorption operation and the functional properties of hydrogel adsorbents could eliminate this method's drawbacks. Herein, three innovative in-situ remediation strategies for Pb/Cu-contaminated soil were adopted based on the concept of novel TEMPO-cellulose (TO-NFCs)/lignin/acrylamide@MIL-100(Fe) nanocomposite hydrogel adsorbent (NCLMH). Characteristic analyses revealed ideal Pb/Cu adsorption mechanisms by swelling, complexation, electrical attraction, and ion exchange via carboxyl/hydroxyl/carbonyl groups and unsaturated Fe(III) sites on ANCMH besides FeOOH formation. The highest maximum theoretical adsorption capacities of Pb(II) and Cu(II) on ANCMH were 416.39 and 133.98 mg/g, under pH 6.5, governed by pseudo-second-order/Freundlich models. Greenhouse pot experiments with contaminated soils amended with two-depth layers of 0.5% NCLMHs (SA@NCLMH) displayed a decline in Pb and Cu bioavailability up to 85.9% and 74.5% within 45 d. Soil column studies simulating continuous water soil flushing coupled with NCLMH layers, instead of conventional extractant fluids, and connected to NCLMH-sand column as purification unit (CF@NCLMH) achieved higher removal rates for Pb, and Cu of 89.5% and 77.2% within 24 h. Alternatively, conducting multiple-pulse soil flushing mode (MF@NCLMH) gained the highest Pb and Cu removal of 96.5% and 85.4%, as the water flushing-stop flux events allowed adequate water movement/residence period, promoting Pb/Cu desorption-adsorption from soil to NCLMH. Also, the NCLMH-sand column conducting and easy separation of the stable/reusable NCLMHs prevented the potential secondary pollution. Interestingly, the three remediated soils reached the corresponding regulation of the permissible limits for Pb and Cu residential scenarios in medium-to-heavily agricultural polluted soils, alleviating the Pb/Cu bioaccumulation and phytotoxicity symptoms in cultivated wheat, especially after MF@NCLMH treatment. This study introduces promising alternative remediation strategies with high sustainability and feasibility in acidic-to-neutral heavy metal-contaminated agricultural soil. [Display omitted] • TO-NFCs/lignin/AM@MIL-100(Fe) nanocomposite hydrogel adsorbent (NCLMH) was fabricated. • The maximum adsorption capacities of Pb and Cu were 416.39 and 133.98 mg/g. • Three in-situ remediation approaches for Pb and Cu in soil were designed based on stable/reusable NCLMH. • The highest removal rates of HMIs were in soil treated by multiple-pulse soil flushing coupled with NCLMHs. • Phytotoxicity tests showed the feasibility of these remediation methods for agricultural soil. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
33. EXPLORING THE SAFETY OF CONDUCTING ERCP IN DECOMPENSATED CIRRHOSIS: INSIGHTS FROM A QUATERNARY CARE TRANSPLANT CENTER.
- Author
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Nimri, Faisal, Jamali, Taher, Dawod, Sanad, Ali, Suhib Alhaj, Alluri, Spandana, Youssef, Rami, Faisal, Muhammad Saad, Omeish, Haya, Alomari, Ahmad, Abusuliman, Muhammad, Saleem, Abdulmalik, Faisal, Muhammad Salman, Singla, Sumit, and Zuchelli, Tobias
- Published
- 2024
- Full Text
- View/download PDF
34. Sa1595 SPONTANEOUS BACTERIAL PERITONITIS: CAN WE PREDICT WHO RESPONDS TO TREATMENT?
- Author
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Dawod, Sanad M., Ali, Suhib Alhaj, Kostecki, Polo, Omeish, Haya, Hasso, Muneer, Elshebiny, Hassan, Kasmikha, Lauren, Kadouh, Ali, Qasawa, Austin, Ishak, Angela, and Venkat, Deepak
- Published
- 2024
- Full Text
- View/download PDF
35. MiOS, an integrated imaging and computational strategy to model gene folding with nucleosome resolution
- Author
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Neguembor, Maria Victoria, Arcon, Juan Pablo, Buitrago, Diana, Lema, Rafael, Walther, Jürgen, Garate, Ximena, Martin, Laura, Romero, Pablo, AlHaj Abed, Jumana, Gut, Marta, Blanc, Julie, Lakadamyali, Melike, Wu, Chao-ting, Brun Heath, Isabelle, Orozco, Modesto, Dans, Pablo D., and Cosma, Maria Pia
- Abstract
The linear sequence of DNA provides invaluable information about genes and their regulatory elements along chromosomes. However, to fully understand gene function and regulation, we need to dissect how genes physically fold in the three-dimensional nuclear space. Here we describe immuno-OligoSTORM, an imaging strategy that reveals the distribution of nucleosomes within specific genes in super-resolution, through the simultaneous visualization of DNA and histones. We combine immuno-OligoSTORM with restraint-based and coarse-grained modeling approaches to integrate super-resolution imaging data with Hi-C contact frequencies and deconvoluted micrococcal nuclease-sequencing information. The resulting method, called Modeling immuno-OligoSTORM, allows quantitative modeling of genes with nucleosome resolution and provides information about chromatin accessibility for regulatory factors, such as RNA polymerase II. With Modeling immuno-OligoSTORM, we explore intercellular variability, transcriptional-dependent gene conformation, and folding of housekeeping and pluripotency-related genes in human pluripotent and differentiated cells, thereby obtaining the highest degree of data integration achieved so far to our knowledge.
- Published
- 2022
- Full Text
- View/download PDF
36. Impact of Rituximab and Corticosteroids on Late Cytopenias Post-Chimeric Antigen Receptor T Cell Therapy
- Author
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Iqbal, Madiha, Bansal, Radhika, Yassine, Farah, Gandhi, Sangeetha, Rosenthal, Allison, Moustafa, Muhamad Alhaj, Li, Zhuo, Craver, Emily C., Mohty, Razan, Murthy, Hemant, Ayala, Ernesto, Tun, Han, Munoz, Javier, Castro, Januario, Lin, Yi, and Kharfan-Dabaja, Mohamed A.
- Abstract
•Cytopenias represent significant adverse events of chimeric antigen receptor (CAR) T cell therapy.•Increased exposure to rituximab pre-CAR T cell therapy is associated with persistent anemia and thrombocytopenia post-CAR T cell therapy.•An increased number of prior lines of therapy is associated with persistent lymphopenia and anemia post-CAR T cell therapy.
- Published
- 2022
- Full Text
- View/download PDF
37. The prevalence of feeding and eating disorders symptomology in medical students: an updated systematic review, meta-analysis, and meta-regression
- Author
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Fekih-Romdhane, Feten, Daher-Nashif, Suhad, Alhuwailah, Amthal H., Al Gahtani, Haifa Mohammed Saleh, Hubail, Suad Abdulla, Shuwiekh, Hanaa Ahmed Mohamed, Khudhair, Mina Fattah, Alhaj, Omar A., Bragazzi, Nicola Luigi, and Jahrami, Haitham
- Abstract
Purpose: Medical students have a higher risk of developing psychological issues, such as feeding and eating disorders (FEDs). In the past few years, a major increase was observed in the number of studies on the topic. The goal of this review was to estimate the prevalence risk of FEDs and its associated risk factors in medical students. Methods: Nine electronic databases were used to conduct an electronic search from the inception of the databases until 15
th September 2021. The DerSimonian–Laird technique was used to pool the estimates using random-effects meta-analysis. The prevalence of FEDs risk in medical students was the major outcome of interest. Data were analyzed globally, by country, by research measure and by culture. Sex, age, and body mass index were examined as potential confounders using meta-regression analysis. Results: A random-effects meta-analysis evaluating the prevalence of FEDs in medical students (K = 35, N = 21,383) generated a pooled prevalence rate of 17.35% (95% CI 14.15–21.10%), heterogeneity [Q = 1528 (34), P = 0.001], τ2 = 0.51 (95% CI 0.36–1.05), τ= 0.71 (95% CI 0.59–1.02), I2 = 97.8%; H= 6.70 (95% CI 6.19–7.26). Age and sex were not significant predictors. Body mass index, culture and used research tool were significant confounders. Conclusion: The prevalence of FEDs symptoms in medical students was estimated to be 17.35%. Future prospective studies are urgently needed to construct prevention and treatment programs to provide better outcomes for students at risk of or suffering from FEDs. Level of evidence: Level I, systematic review and meta-analysis.- Published
- 2022
- Full Text
- View/download PDF
38. Evaluation of using waste pinecones as an eco-friendly additive to water-based mud.
- Author
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Al Khalaf, Hani, Mohammed, Nagham Alhaj, and Kovacsne, Gabriella Federer
- Subjects
PINE cones ,DRILLING muds ,SITKA spruce ,AGRICULTURAL wastes ,MUD ,FUEL additives - Abstract
Copyright of Rudarsko-Geolosko-Naftni Zbornik is the property of Faculty of Mining, Geology & Petroleum Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
- Full Text
- View/download PDF
39. The Validation and Reliability of the Food and Health Questionnaire to Assess Health and Nutrition Knowledge.
- Author
-
Alhaj, Omar A., Al-Sayyed, Hiba F., Charouf, Ola M., Jahrami, Haitham, and Morris, Keith
- Abstract
Purpose: This study aimed to translate and test the content validity and reliability of an English questionnaire used in the American food and health survey. Methods: The questionnaire was developed using 6 stages, then examined for test–retest. A total of 672 participants were recruited for validation and reliability. Validity test was performed using a correlation coefficient to measure the linear correlation between 2 questions at one given time. Moreover, the Kaiser-Meyer-Olkin, Measure of Sampling Adequacy, and Bartlett's Test of Sphericity were performed to statistically determine the suitability for conducting exploratory factor analysis. Furthermore, reliability tests using Cronbach α was used to estimate the reliability coefficient properties of the translated scale. Finally, the most important correlated questions was plotted using a color-coded correlogram. Results: The test–retest reliability of all tested items was significantly correlated. The reliability test for all questions was 0.9. The cross-correlation test showed that all questions of the translated questionnaire were correlated significantly (P <.05) indicating reliability of the questionnaire. Conclusion: The tested questionnaire is applicable and may be used in population-based studies to raise awareness regarding health, food consumption, nutrition, and food safety among people in Jordan and/or other Arab countries. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
40. Nitrogen Deep Placement Combined with Straw Mulch Cultivation Enhances Physiological Traits, Grain Yield and Nitrogen Use Efficiency in Mechanical Pot-Seedling Transplanting Rice.
- Author
-
Lin, Li, Zheng, Zhang, Hua, Tian, Ashraf, Umair, Hamoud, Yousef Alhaj, Alaa, Al Aasmi, Xiangru, Tang, Meiyang, Duan, Zaiman, Wang, and Shenggang, Pan
- Subjects
RICE straw ,MECHANICAL efficiency ,STRAW ,LEAF area index ,NITRATE reductase ,GLUTAMINE synthetase - Abstract
To assess the effects of straw return coupled with deep nitrogen (N) fertilization on grain yield and N use efficiency (NUE) in mechanical pot-seedling transplanting (MPST) rice, the seedlings of two rice cultivars, i.e., Yuxiangyouzhan and Wufengyou 615 transplanted by MPST were applied with N fertilizer at 150 kg/hm
2 and straw return at 6 t/hm2 in early seasons of 2019 and 2020. The experiment comprised of following treatments: CK (no fertilizer and no straw return), MDS (deep N fertilization and straw return), MBS (broadcasting fertilizer and straw return), MD (deep N fertilization without straw return), MB (broadcasting fertilizer without straw return). Results depicted that the MDS treatment significantly increased the rice yield by 41.69%–72.22% due to total above-ground biomass, leaf area index and photosynthesis increased by 54.70%–55.80%, 38.52%–52.17% and 17.89%–28.40%, respectively, compared to the MB treatment. In addition, the MDS treatment enhanced the total N accumulation by 37.74%–43.69%, N recovery efficiency by 141.45%–164.65%, N agronomic efficiency by 121.76%–134.19%, nitrate reductase by 46.46%–60.86% and glutamine synthetase by 23.56%–31.02%, compared to the MB treatment. The average grain yield and NUE in both years for Yuxiangyouzhan were higher in the MDS treatment than in the MD treatment. Hence, deep N fertilization combined with straw return can be an innovative technique with improved grain yield and NUE in MPST in South China. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
41. A real-world study of combined modality therapy for early-stage Hodgkin lymphoma: too little treatment impacts outcome
- Author
-
Chohan, Karan L., Young, Jason R., Lester, Scott, Alhaj Moustafa, Muhamad, Rosenthal, Allison, Tun, Han W., Hoppe, Bradford S., Johnston, Patrick B., Micallef, Ivana N., Habermann, Thomas M., and Ansell, Stephen M.
- Abstract
Multiple clinical trials have assessed de-escalation strategies from combined modality therapy (CMT) to chemotherapy-alone for the treatment of early-stage classical Hodgkin lymphoma (cHL), confirming similar outcomes. The application of these data to the real-world is limited, however. We conducted a retrospective, multicenter cohort study comparing CMT vs chemotherapy-alone in patients with early-stage cHL (stage IA-IIB) treated between January 2010 and December 2020. Positron emission tomography (PET) scans after chemotherapy cycle 2 (PET2) were independently reviewed by a nuclear radiologist (Deauville score ≥4, positive; ≤3, negative). Patient outcomes were compared by using an intention-to-treat analysis. Among 125 patients (CMT, n = 63; chemotherapy-alone, n = 62) with a median follow-up of 59.8 months (95% CI, 48.6-71.0), no differences in overall survival were observed (5-year overall survival, CMT 98.0% vs chemotherapy-alone 95.1%; log-rank test, P = .38). However, there was reduced progression-free survival (PFS) with chemotherapy-alone among all patients (2-year PFS, CMT 95.1% vs chemotherapy-alone 75.3%; log-rank test, P = .005) and in those with bulky (n = 43; log-rank test, P < .001), unfavorable (n = 81; log-rank test, P = .002), or PET2-positive (n = 15; log-rank test, P = .02) disease. No significant differences in PFS were seen for patients with non-bulky (log-rank test, P = .35), favorable (log-rank test, P = .62), or PET2-negative (log-rank test, P = .19) disease. Based on our real-world experience, CMT seems beneficial for patients with early-stage cHL, especially those with PET2-positive and unfavorable disease. Chemotherapy-alone regimens can lead to comparable outcomes for patients with favorable, non-bulky, or PET2-negative disease. We conclude that although results seen in clinical trials are replicated in certain patient subgroups, other subgroups not fitting trial criteria do poorly when radiotherapy is excluded.
- Published
- 2022
- Full Text
- View/download PDF
42. A real-world study of combined modality therapy for early-stage Hodgkin lymphoma: too little treatment impacts outcome
- Author
-
Chohan, Karan L., Young, Jason R., Lester, Scott, Alhaj Moustafa, Muhamad, Rosenthal, Allison, Tun, Han W., Hoppe, Bradford S., Johnston, Patrick B., Micallef, Ivana N., Habermann, Thomas M., and Ansell, Stephen M.
- Abstract
Multiple clinical trials have assessed de-escalation strategies from combined modality therapy (CMT) to chemotherapy-alone for the treatment of early-stage classical Hodgkin lymphoma (cHL), confirming similar outcomes. The application of these data to the real-world is limited, however. We conducted a retrospective, multicenter cohort study comparing CMT vs chemotherapy-alone in patients with early-stage cHL (stage IA-IIB) treated between January 2010 and December 2020. Positron emission tomography (PET) scans after chemotherapy cycle 2 (PET2) were independently reviewed by a nuclear radiologist (Deauville score ≥4, positive; ≤3, negative). Patient outcomes were compared by using an intention-to-treat analysis. Among 125 patients (CMT, n = 63; chemotherapy-alone, n = 62) with a median follow-up of 59.8 months (95% CI, 48.6-71.0), no differences in overall survival were observed (5-year overall survival, CMT 98.0% vs chemotherapy-alone 95.1%; log-rank test, P= .38). However, there was reduced progression-free survival (PFS) with chemotherapy-alone among all patients (2-year PFS, CMT 95.1% vs chemotherapy-alone 75.3%; log-rank test, P= .005) and in those with bulky (n = 43; log-rank test, P< .001), unfavorable (n = 81; log-rank test, P= .002), or PET2-positive (n = 15; log-rank test, P= .02) disease. No significant differences in PFS were seen for patients with non-bulky (log-rank test, P= .35), favorable (log-rank test, P= .62), or PET2-negative (log-rank test, P= .19) disease. Based on our real-world experience, CMT seems beneficial for patients with early-stage cHL, especially those with PET2-positive and unfavorable disease. Chemotherapy-alone regimens can lead to comparable outcomes for patients with favorable, non-bulky, or PET2-negative disease. We conclude that although results seen in clinical trials are replicated in certain patient subgroups, other subgroups not fitting trial criteria do poorly when radiotherapy is excluded.
- Published
- 2022
- Full Text
- View/download PDF
43. Revealing the surprising: Computed tomography-guided exploration of paranasal sinuses incidental findings
- Author
-
Zidan, Mogahid M.A., Altayeb, Abrar, Altayeb, Assala, Alhaj, Ahmed, Khalid, Ahmed, Haytham, Reem, Alwaseela, Nihad, Abd Elraheim, Amel Alsaied Hasan, Elgyoum, Ala M.A., Alzain, Amel F.H., Ageed, Fatima Eltayb M., Fagiry, Moram A., Alhailiy, Ali Bahny, Osman, Hamid, Elkhader, Bahaaedin A., Alqahtani, Mohammed S., and Mahmoud, Mustafa
- Abstract
Incidental findings (IFs) are unintentional discoveries that are unrelated to the original imaging goal. Imaging exams of persons with suspected intracranial disorders may reveal IFs in the paranasal sinuses (PNS). The current investigation aims to determine the frequency and features of unexpected discoveries in the PNS in persons who have had brain computed tomography (CT) scans for suspected intracranial abnormalities.
- Published
- 2024
- Full Text
- View/download PDF
44. A systematic review, meta-analysis, and meta-regression of the prevalence of self-reported disordered eating and associated factors among athletes worldwide
- Author
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Ghazzawi, Hadeel A., Nimer, Lana S., Haddad, Areen Jamal, Alhaj, Omar A., Amawi, Adam T., Pandi-Perumal, Seithikurippu R., Trabelsi, Khaled, Seeman, Mary V., and Jahrami, Haitham
- Abstract
Disordered eating (DE) refers to eating behaviors that limit food choices, reduce or exaggerate food intake, cause physical discomfort, create a sense of loss of control, or lead to negative emotions like shame or guilt. The DE label does not signify the presence of a diagnosed mental health disorder, but, rather, describes self-reported, regular eating patterns that psychiatrists consider to fall into the at-risk category for an eating disorder. In this review, we performed a search of academic databases to find all relevant studies that measured the frequency of self-reported DE in athletes. We analyzed 177 studies involving over 70,000 athletes in total. In this study, DE was defined as a score above cut-off on validated screening tests for problematic eating behaviors. Our goal was to estimate the prevalence of DE in athletes globally and to determine the factors that increase risk. We found that approximately 1 in 5 athletes (19%) endorsed DE behaviors such as, among others, restrictive dieting, bingeing, and purging. These behaviors were seen most commonly in indoor sports like gymnastics and less commonly in the context of outdoor sports. Rates were highest in female athletes, older athletes, athletes with high body mass index (BMI) scores, and those from Eastern countries and cultures. Australia had the highest rates (over 50%), while rates were lowest in Iceland. We suggest the development of screening tests specifically tailored and applicable to athletes. In addition, we recommend raising public awareness of the health effects of nutrition in sports.
- Published
- 2024
- Full Text
- View/download PDF
45. Fatigue Fracture Investigation of Engineered Cementitious Composites.
- Author
-
Shuling Gao, Lin Qi, Wenchang Wang, Guanhua Hu, Hongfei Shi, and Alhaj, Abdullah
- Abstract
The fracture failure and crack propagation of engineered cementitious composites (ECC) are analyzed based on extended finite element method (XFEM) simulation and experiment. Three-point bending notched beam under static and fatigue load is employed in this research. As a result, the peak loads in the experiment were consistent with simulation results, while the simulated crack mouth opening displacement (CMOD) values corresponding to the peak loads were generally smaller than the experimental results. In addition, it was observed that a single crack's propagation occurred along the initial notch in numerical simulation rather than multiple cracks' propagation. Though the cycle times of fatigue load were short in the simulation of fatigue fracture under low-stress level and high cycle frequency, the loading cycle frequency had a negligible influence on simulation. However, the higher the stress level was, the greater the effect of the loading cycle frequency on the simulation results. A higher loading frequency will reduce the model's load carrying capacity. The results showed that the XFEM can simulate the crack propagation behavior and get the strain hardening vertical load-CMOD curve of ECC to a certain extent. XFEM provides a convenient way to solve complex practical engineering problems of ECC with the strain hardening property. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
46. Acute Care Nurse Practitioner Students' Perceptions of a Debriefing Experience After a Cardiac Emergency High-Fidelity Simulation: A Qualitative Study.
- Author
-
Ali, Abeer Alhaj, Miller, Elaine, Musallam, Eyad, and Ballman, Kathleen
- Abstract
Acute care nurse practitioners need specialized training to prepare for their advanced role. Limited research investigates acute care nurse practitioners' leadership skills related to team dynamics and evidence-based practices. This study explored students' perceptions of a simulation and debriefing experience and the effects of debriefing on their ability to transfer their leadership-related learning. A qualitative exploratory approach was used. Students (N = 28) were divided between a video-assisted debriefing group (n = 16) and a verbal debriefing group (n = 12). Focus group interviews were conducted in order to explore students' experience of acting as team leader when managing emergency dysrhythmias during high-fidelity simulation code scenarios. Three themes emerged: leadership training, video-assisted debriefing and verbal debriefing, and transferability. This study adds valuable information about how simulation technology could be used in leadership skills learning by and training for nurse practitioners. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
47. A summer of fear.
- Author
-
Ali, Eman Alhaj
- Abstract
The sea does not symbolize freedom in 2024. [ABSTRACT FROM AUTHOR]
- Published
- 2024
48. Craving the simple pleasures of Eid.
- Author
-
Ali, Eman Alhaj
- Abstract
Human rights now seem out of reach. [ABSTRACT FROM AUTHOR]
- Published
- 2024
49. Knowledge is going up in smoke.
- Author
-
Ali, Eman Alhaj
- Abstract
Gaza's people have no option than to burn books. [ABSTRACT FROM AUTHOR]
- Published
- 2024
50. The Validation and Reliability of the Food and Health Questionnaire to Assess Health and Nutrition Knowledge
- Author
-
Alhaj, Omar A., Al-Sayyed, Hiba F., Charouf, Ola M., Jahrami, Haitham, and Morris, Keith
- Abstract
Purpose: This study aimed to translate and test the content validity and reliability of an English questionnaire used in the American food and health survey.Methods: The questionnaire was developed using 6 stages, then examined for test–retest. A total of 672 participants were recruited for validation and reliability. Validity test was performed using a correlation coefficient to measure the linear correlation between 2 questions at one given time. Moreover, the Kaiser-Meyer-Olkin, Measure of Sampling Adequacy, and Bartlett’s Test of Sphericity were performed to statistically determine the suitability for conducting exploratory factor analysis. Furthermore, reliability tests using Cronbach α was used to estimate the reliability coefficient properties of the translated scale. Finally, the most important correlated questions was plotted using a color-coded correlogram.Results: The test–retest reliability of all tested items was significantly correlated. The reliability test for all questions was 0.9. The cross-correlation test showed that all questions of the translated questionnaire were correlated significantly (P< .05) indicating reliability of the questionnaire.Conclusion: The tested questionnaire is applicable and may be used in population-based studies to raise awareness regarding health, food consumption, nutrition, and food safety among people in Jordan and/or other Arab countries.
- Published
- 2022
- Full Text
- View/download PDF
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