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A US Multicenter Collaborative Study on Outcomes of Hematopoietic Cell Transplantation in Hepatosplenic T-Cell Lymphoma

Authors :
Moustafa, Muhamad Alhaj
Ramdial, Jeremy L.
Tsalatsanis, Athanasios
Khimani, Farhad
Dholaria, Bhagirathbhai
Bojanini, Leyla
Brooks, Taylor Rey
Zain, Jasmine
Bennani, N. Nora
Braunstein, Zachary
Brammer, Jonathan E.
Beitinjaneh, Amer
Jagadeesh, Deepa
Weng, Wen Kai
Kumar, Ambuj
Kharfan-Dabaja, Mohamed A.
Ahmed, Sairah
Murthy, Hemant S.
Source :
Transplantation and Cellular Therapy; May 2024, Vol. 30 Issue: 5 p516.e1-516.e10, 46450p
Publication Year :
2024

Abstract

•Autologous and allogeneic hematopoietic cell transplantation are both effective consolidative strategies in patients with Hepatosplenic T Cell Lymphoma.•Median overall survival and progression free survival for the entire cohort were 78.5 months (95% CI: 25-NR) and 54 months (95% CI: 18 to 75), respectively.•No significant differences in OS or PFS we seen when comparing autologous and allogeneic HCT groups.•Pts with less than CR at time of transplant had better median overall survival with allogeneic hematopoietic cell transplantation compared to autologous hematopoietic cell transplantation (65 mo versus 7 mo, P< .001).

Details

Language :
English
ISSN :
26666375 and 26666367
Volume :
30
Issue :
5
Database :
Supplemental Index
Journal :
Transplantation and Cellular Therapy
Publication Type :
Periodical
Accession number :
ejs65622229
Full Text :
https://doi.org/10.1016/j.jtct.2024.02.021