Search

Volpara Health, a global leader in AI-powered breast health solutions, has achieved a milestone of 300 peer-reviewed scientific papers, demonstrating its commitment to advancing breast cancer detection and personalized care. The company's technology has earned trust within academic and clinical communities, with studies showing improvements in radiologist performance and the identification of women at higher risk for missed cancers. Volpara's dedication to scientific rigor and innovation over 15 years underscores its mission to enhance breast health through AI technology. [Extracted from the article]

A patent was issued for banded papers, smoking articles, and methods by inventors from Virginia, with Altria Client Services LLC as the assignee. The patent focuses on reducing accidental fires from smoking articles by measuring Ignition Propensity and Self-Extinguishment values. The patent describes a wrapper for smoking articles with a film-forming compound pattern to improve safety and consumer satisfaction. This patent aims to enhance smoking article safety and user experience through innovative design and materials. [Extracted from the article]

Jiangsu Bioperfectus Technologies Co. Ltd. has filed a patent application for an auxiliary test paper detection device that aims to improve pathogen detection. The device addresses the limitations of current methods by reducing waiting times, cross-infection risks, and costs associated with hospital treatment. It consists of a reagent cap and a test paper cassette, which form a closed space for sample absorption. The device simplifies the detection process, prevents environmental pollution, and allows for autonomous operation at home. The patent application provides further details and claims. [Extracted from the article]

A patent application has been filed by James A. Kaslik for a device that can transform toilet paper in real time to improve its effectiveness at cleaning residue off the skin and body hair. The device is pocket-sized and can be carried anywhere. It uses liquid, a mold, and pressure to transform the texture, density, and wetness of the paper. The transformed paper provides superior cleaning and decomposes in water without causing harm to sewage and septic systems. Various variations of the device are also described in the patent application. [Extracted from the article]

A patent application by Philip Morris USA Inc. has been made available online, detailing the invention of banded papers and smoking articles. The application explains that the invention aims to reduce the incidence of accidental fires caused by untended smoking articles. The invention focuses on reducing the Ignition Propensity (IP) value and increasing the Self-Extinction (SE) value of smoking articles. The application describes the testing methods for IP and SE values and discusses the use of an aqueous starch solution with an anti-wrinkling agent to achieve the desired results. The invention also includes patterns and characteristics for the add-on material used in the wrapper paper. [Extracted from the article]

A patent has been issued for a manufacturing process of intermittent coating release paper by Foshan XinFei Hygiene Materials Co. Ltd. The patent addresses the technical problems associated with the production of release paper used in sanitary napkins and other similar products. The process involves steps such as undercoating, primary drying, printing optical marks, coating silicone oil, and accurately coating heat-sealing material. The patent provides specific details about the viscosity of the silicone oil and heat-sealing material, as well as the alignment and precision of the coating rollers. The process aims to solve technical defects and meet the actual needs of the industry. [Extracted from the article]

A recent study conducted by researchers at Amrita Vishwa Vidyapeetham in Kerala, India, has shed light on the deceptive practices of predatory journals. The study analyzed three datasets of calls for papers from potential predatory journals and legitimate journals using text mining and programming language. The researchers found that most potential predatory journals use similar language and templates in their calls for papers, often using flattering and positive words that are rarely seen in emails from legitimate journals. Based on these findings, the researchers developed a toolkit for detecting unsolicited calls for papers from potential predatory journals. This research provides valuable insights and tools for distinguishing between predatory and legitimate journals, ultimately helping researchers deal with predatory journals more effectively. [Extracted from the article]

Leadway (Hk) Limited has submitted a patent application for a test device and test paper that can be used for point-of-care testing (POCT). The test strip includes a positioning hole and a positioning column to ensure accurate placement in a test cassette. The positioning hole is slightly larger than the positioning column, making insertion easier and reducing misalignment. This invention aims to improve the success rate of mounting the test strip and reduce scrap rates during production. Library patrons conducting research can rely on Leadway (Hk) Limited's reports for factual and reliable information on various topics worldwide. [Extracted from the article]

Acupath LABORATORIES INC., Biomarkers, Bladder Cancer, Business, Cancer, Cancer Biomarkers, Carcinoma Biomarkers, Cytology, Diagnostics and Screening, Health and Medicine, Oncology, Risk and Prevention Keywords: Acupath LABORATORIES INC.; Biomarkers; Bladder Cancer; Business; Cancer; Cancer Biomarkers; Carcinoma Biomarkers; Cytology; Diagnostics and Screening; Health and Medicine; Oncology; Risk and Prevention EN Acupath LABORATORIES INC. Biomarkers Bladder Cancer Business Cancer Cancer Biomarkers Carcinoma Biomarkers Cytology Diagnostics and Screening Health and Medicine Oncology Risk and Prevention 69 69 1 09/19/23 20230919 NES 230919 2023 SEP 19 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Acupath Labs released a white paper highlighting the impressive results of a large-scale internal study analyzing the clinical utility of its Acu-UR017 bladder cancer biomarker. [Extracted from the article]

Punjab, India, Asia, Business, Emerging Technologies, Nanoparticles, Nanotechnology Keywords: Punjab; India; Asia; Business; Emerging Technologies; Nanoparticles; Nanotechnology EN Punjab India Asia Business Emerging Technologies Nanoparticles Nanotechnology 2576 2576 1 10/16/23 20231020 NES 231020 2023 OCT 20 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Researchers detail new data in Nanotechnology - Nanoparticles. [Extracted from the article]

Therefore, we explain PK concepts of biodistribution of AAV-based therapies and place key terminologies related to drug exposure and PD in the proper context. Keywords for this news article include: Philadelphia, Pennsylvania, United States, North and Central America, Bioengineering, Biopharmaceutical Companies, Biotechnology, Business, Drugs and Therapies, Gene Therapy, Genetics, Healthcare Biotechnology Companies, Technology, Therapy, Spark Therapeutics Inc. Keywords: Philadelphia; State:Pennsylvania; United States; North and Central America; Bioengineering; Biopharmaceutical Companies; Biotechnology; Business; Drugs and Therapies; Gene Therapy; Genetics; Healthcare Biotechnology Companies; Technology; Therapy EN Philadelphia State:Pennsylvania United States North and Central America Bioengineering Biopharmaceutical Companies Biotechnology Business Drugs and Therapies Gene Therapy Genetics Healthcare Biotechnology Companies Technology Therapy 919 919 1 09/04/23 20230908 NES 230908 2023 SEP 8 (NewsRx) -- By a News Reporter-Staff News Editor at Gene Therapy Weekly -- Research findings on Biotechnology - Gene Therapy are discussed in a new report. [Extracted from the article]

"In the conventional GA-based biosensor, folding and/or twisting of alkane chains leads to crosslinking amongst the aldehyde itself, and thereby limits the sensitivity of the biosensor over time. Protein Sensing Platform With A Combination Of Conducting Polymers, Aromatic And Conjugated Aldehydes On A Cellulose Paper Base. Keywords: Acyclic Hydrocarbons; Aldehydes; Alkenes; Biosensors; Biotechnology; Business; COVID-19; Coronavirus; Emerging Technologies; Ethylenes; Nanotechnology; Nanowires; Opteev Technologies Inc.; Organic Chemicals; RNA Viruses; SARS-CoV-2; Severe Acute Respiratory Syndrome Coronavirus 2; Viral; Virology; Viruses EN Acyclic Hydrocarbons Aldehydes Alkenes Biosensors Biotechnology Business COVID-19 Coronavirus Emerging Technologies Ethylenes Nanotechnology Nanowires Opteev Technologies Inc. Organic Chemicals RNA Viruses SARS-CoV-2 Severe Acute Respiratory Syndrome Coronavirus 2 Viral Virology Viruses 1351 1351 1 08/14/23 20230820 NES 230820 2023 AUG 20 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Letter on the CDC & FDA -- A patent application by the inventors BESSEMER, Conrad (Millersville, MD, US); CHATTERJEE, Sauvik (Dist-Hooghly, IN); CHATTERJEE, Soumyo (Kolkata, IN); PAL, Biplab (Ellicot City, MD, US), filed on January 23, 2023, was made available online on July 27, 2023, according to news reporting originating from Washington, D.C., by NewsRx correspondents. [Extracted from the article]

Keywords: Business; Newell Brands; Newell Rubbermaid Inc.; Social Media EN Business Newell Brands Newell Rubbermaid Inc. Social Media 3425 3425 1 05/08/23 20230511 NES 230511 2023 MAY 12 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Letter on the CDC & FDA -- Paper Mate, a #1 Teacher Choice brand and part of the Newell Brands global portfolio of brands, announced its partnership with actor and children's book author, Max Greenfield, alongside its non-profit partner, AdoptAClassroom.org, to kick off the brand's Thanks to Teachers initiative. Max Greenfield and Paper Mate are encouraging everyone to thank their teachers, past and present, for their hard work and dedication, and encourage the use of the hashtag #ThankstoTeachers when sharing on social media. [Extracted from the article]

The wrapper of claim 93, wherein the second banded layer includes, a first layer adjacent to the second base side, and a second layer adjacent to an exposed surface of the first layer; the first layer includes a first starch, a first chalk, the second anti-wrinkling agent, or any combination thereof; the second layer includes a second starch, a second chalk, the second anti-wrinkling agent, or any combination thereof; the first starch is same as or different from the second starch; and the first chalk is same as or different from the second chalk. The wrapper of claim 93, wherein the first banded layer includes, a first layer adjacent to the first base side, and a second layer disposed adjacent to an exposed surface of the first layer; the first layer includes a first starch, a first chalk, the first anti-wrinkling agent, or any combination thereof; the second layer includes a second starch, a second chalk, the first anti-wrinkling agent, or any combination thereof; the first starch is same as or different from the second starch; and the first chalk is same as or different from the second chalk. [Extracted from the article]

Business, Health and Medicine, Imaging Technology Companies, Olympus, Olympus Corporation, Surgery, Technology Keywords: Business; Health and Medicine; Imaging Technology Companies; Olympus; Olympus Corporation; Surgery; Technology EN Business Health and Medicine Imaging Technology Companies Olympus Olympus Corporation Surgery Technology 2023 FEB 12 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Olympus announced the availability of several Experience Papers focused on the benefits of advancements in electrosurgical devices. [Extracted from the article]

Keywords: Indianapolis; State:Indiana; United States; North and Central America; Biotechnology; Business; Drugs and Therapies; Health and Medicine; Inflammation; Pharmaceutical Companies; Protein Therapy; Proteomics EN Indianapolis State:Indiana United States North and Central America Biotechnology Business Drugs and Therapies Health and Medicine Inflammation Pharmaceutical Companies Protein Therapy Proteomics 1675 1675 1 03/24/23 20230224 NES 230224 2023 FEB 24 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Data detailed on Drugs and Therapies - Protein Therapy have been presented. Disease states that have been shown to result in indirect disease-DIs that are clinically meaningful have been listed (i.e., typically a twofold change in the systemic exposure of a coadministered sensitive cytochrome P450 substrate drug). [Extracted from the article]

The article offers business news briefs for western North Carolina region as of September 2014. Paper mill Evergreen Packaging Inc. seeks $12 million state aid to help pay for modernized boilers to meet federal rules on emission. Duke LifePoint Healthcare has purchased MedWest Haywood. Beer maker Wicked Weed Brewing plans to build a brewery in Candler, which will create 82 jobs over three years.

A research paper titled "The cell rejuvenation atlas: leveraging network biology to identify master regulators of rejuvenation strategies" was recently published in the journal Aging. The paper discusses the limitations of current rejuvenation strategies and the need for more comprehensive approaches. The researchers developed a cell rejuvenation atlas called SINGULAR, which analyzes the effects of various rejuvenation strategies at the cellular level. They identified master regulators and common targets across immune cells, and demonstrated how SINGULAR can be used to select drugs that mimic the effects of complex interventions. The researchers believe that SINGULAR will be useful in advancing human age reversal. [Extracted from the article]

A research paper published in Oncotarget discusses the development of a nanodrug called MN-anti-miR10b, which delivers anti-miR-10b antisense oligomers to cancer cells. The paper highlights the poor prognosis for metastatic breast cancer and the role of miR-10b in driving metastasis. The researchers found that inhibiting miR-10b with MN-anti-miR10b activates developmental processes in cancer cells and decreases their stemness. In mouse models, MN-anti-miR10b was shown to prevent the onset of metastasis and eliminate existing metastases when combined with chemotherapy. The study suggests that MN-anti-miR10b could be a potential therapy for metastatic breast cancer. [Extracted from the article]

SWM Holdings US LLC has been issued a patent for a coated plug wrap for a smoking article. The patent describes the use of a base paper made from hardwood pulp fibers and softwood pulp fibers, coated with materials such as acrylate, styrene, or butadiene. The coated plug wrap aims to increase the strength of the paper, prevent flavorings from escaping, and prevent air from diluting the aromas of the smoking article. The patent also includes claims for the composition and process of producing the coated plug wrap. [Extracted from the article]

A new editorial paper published in Oncotarget discusses the role of HER2 in breast cancer. HER2 is a prognostic and predictive factor in breast cancer, associated with a poor prognosis but also offering the chance of improved survival with targeted therapies like trastuzumab. The majority of breast tumors are considered HER2-negative, but recent trials with trastuzumab-based antibody-drug conjugates have challenged this view. The paper explores the implications of these findings. [Extracted from the article]

A new editorial paper published in Oncotarget discusses the targeting of ABC transporters in pancreatic ductal carcinoma (PDAC). PDAC is the third leading cause of cancer mortality in the US and the sixth worldwide, with low survival rates. ABC transporters are a family of proteins that can contribute to resistance against chemotherapy drugs. The paper suggests that developing a stratification protocol to identify PDAC patients who are most likely to benefit from inhibitors of ABC transporters could be crucial for future treatment. [Extracted from the article]

A new editorial paper published in Oncoscience discusses the role of Erk5, a protein belonging to the mitogen-activated protein kinase (MAPK) family, in cancer treatment. The researchers highlight that understanding the function of Erk5 in cancer will contribute to a better understanding of cancer pathogenesis and the development of novel therapeutic strategies. The paper also explores the role of Erk5 in bone homeostasis and its potential applications in cancer treatment. The researchers generated and analyzed conditional Erk5 knockout mice to investigate the function of Erk5 in bone marrow mesenchymal stem cells. [Extracted from the article]

A recent editorial paper published in Oncoscience discusses the challenges of targeted cancer therapy and the need for alternative targeting routes. The researchers highlight the potential of G-protein-coupled receptors (GPCRs) in cancer malignancy and the significance of protease-activated receptors (PARs), a subgroup of GPCRs, as valuable targets for therapy in various types of epithelial malignancies. The paper emphasizes the importance of identifying binding motifs within the C-tails of PAR1,2&4 for drug design and suggests that these motifs could serve as a platform for developing new cancer drugs. [Extracted from the article]

The major newspapers are still struggling from a three-year ad slump, but the community papers of Queens are enjoying a renaissance, thanks to the borough's population growth and its intense local pride. They're attracting readers by giving them stories that the major papers won't, and luring advertisers with a highly targeted audience. Queens boasts nearly 30 community papers published in English. At least a score of titles are targeted to the borough's burgeoning Asian, Eastern European and Latino neighborhoods. Queens papers are doing well because they offer advertisers, especially small businesses, the chance to reach out to a loyal, well-defined readership.

A new editorial paper published in Oncoscience discusses the use of tumor mutation burden (TMB) as a clinical biomarker for predicting the response to immunotherapy in urothelial carcinomas. High TMB has been associated with a positive response to immune checkpoint inhibitors, but not all cancers with high TMB or microsatellite instability (MSI) phenotype respond to immunotherapy. The paper suggests that combining immunotherapy with targeted therapies that address additional molecular defects present in urothelial carcinomas may offer a potential treatment option for immune checkpoint inhibitor-resistant urothelial carcinomas with high TMB and those with low TMB. [Extracted from the article]

A recent editorial paper published in Oncoscience discusses the challenges of developing novel therapeutics for metastatic tumors. The author highlights that tumors that have spread to distant locations, such as the brain, are difficult to treat and cure. While immunotherapeutic approaches have shown success in some tumor types, there is evidence that they may cause hyper-progression in certain patients. The paper emphasizes the need for combination therapies targeting key signaling pathways to effectively control tumor growth and survival. [Extracted from the article]

A recent research paper published in Oncotarget discusses the discovery of a potential biomarker, SSR3, that could predict the response to paclitaxel treatment in glioblastoma and breast cancer patients. The researchers used a whole genome CRISPR knockout screen to identify this biomarker, and it was validated in two independent breast cancer patient cohorts. The paper emphasizes the importance of validating novel biomarkers to improve the efficacy of therapeutic agents, particularly in the context of glioblastoma where treatment outcomes can be unpredictable. The researchers also highlight the need for further identification and validation of predictive biomarkers to enable personalized and precise medicine. [Extracted from the article]

A patent has been issued for an elongated smoking article by Reemtsma Cigarettenfabriken GmbH, developed by inventors Cooper and Fuhrmann. The patent aims to provide smokers with the ability to adjust the intensity of additional flavoring in smoking articles, addressing drawbacks of prior methods. The smoking article includes a cylindrical smoking body, a filter element, and tipping paper with flavoring that varies in distribution, allowing users to customize their smoking experience. [Extracted from the article]

A research paper published in Aging journal explores the use of proteomics to study bone formation in young-adult and old mice. Researchers from Washington University School of Medicine developed a novel proteomics approach and found a correlation between bone proteome and transcriptome. The study highlights the importance of protein-level assays in understanding skeletal biology, emphasizing the need for complementary research methods in this field. [Extracted from the article]

A research paper published in Aging discusses the decline in brain health with age, focusing on cerebral blood flow (CBF) and arterial transit time (ATT) as key markers of brain vascular health. The study by researchers from various universities aimed to identify modifiable determinants of CBF and ATT in healthy older adults and their relationship with cognitive function. Findings suggest that higher BMI is associated with lower CBF and longer ATT, while cardiorespiratory fitness is linked to longer ATT in specific brain regions. The study concludes that preventing excessive weight gain may help mitigate age-related declines in brain vascular health. [Extracted from the article]

A research paper published in Aging (Albany NY) and Aging-US explores the prevalence of frailty in breast cancer and hematopoietic cell transplant survivors and its impact on physical performance and quality of life. The study, conducted by researchers from the University of Minnesota, Amgen, and Columbia University Medical Center, found a high prevalence of frailty in these survivor groups, with detrimental effects on physical functioning and overall well-being. The study also identified an association between frailty and the senescence marker p16INK4a, suggesting the need for further research on senolytic trials in cancer survivors. [Extracted from the article]

A research paper titled "Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeutics" was recently published in Oncotarget's Volume 15. The study explores the restoration of the p53 pathway as a long-term goal in cancer research and compares the activation of p53 target genes by different compounds. The authors found that the compounds PG3 and PG3-Oc upregulate certain genes in cancer cell lines, independent of p53, through ATF4 and the integrated stress response. The study reveals a novel mechanism by which PG3 induces cell death via the HRI/ATF4/PUMA axis. [Extracted from the article]

Vaccine adjuvants have evolved from empirical discovery to a more structured approach grounded in rational drug design. This paper explores the progression of adjuvant research, emphasizing the importance of understanding the structural and functional traits of adjuvants. Techniques such as X-ray crystallography and nuclear magnetic resonance (NMR) are used to establish structure-activity relationships (SARs) and aid in the design of superior adjuvants. The study also highlights the need for comprehensive immunological studies and the challenges in adjuvant research, while emphasizing the potential of adjuvants in treating autoimmune diseases and other conditions requiring immunological modulation. [Extracted from the article]

A research paper published in Aging (Albany NY) explores the role of protein palmitoylation in the development of a DNA damage-induced senescence phenotype. The study conducted by researchers from the Nencki Institute of Experimental Biology in Warsaw, Poland, suggests that protein palmitoylation may regulate cell senescence, providing new insights into age-related diseases. The researchers found that treatment with 2-bromopalmitate, an inhibitor of protein acyltransferases, resulted in changes in the senescent phenotype of human vascular smooth muscle cells, including the resumption of cell proliferation and a decrease in DNA damage markers. This research contributes to the understanding of the mechanisms surrounding aging and age-related diseases. [Extracted from the article]

A patent has been issued for an automated clinical documentation system and method by Microsoft Technology Licensing LLC. The system aims to track procedural events in patient encounters by obtaining encounter information, processing it to generate an encounter transcript, and locating procedural events within the transcript. The system can confirm the identity of encounter participants and authenticate informed medical consent events using audio and machine vision encounter information. This technology has the potential to improve the efficiency and accuracy of clinical documentation in the transition from paper-based to digital records. [Extracted from the article]

A research paper from scientists at Beijing Institute of Technology presents a method of sciatic nerve stimulation that can aid in lower extremity standing and stepping. The study used electrical nerve stimulation to achieve muscle control through different sciatic nerve branches, allowing for regulation of lower limb movements during stepping and standing. The method was found to be effective and reliable for improving and rehabilitating lower limb motor dysfunction. While the experiment showed successful results in hindlimb motion modulation, there are limitations to the control over the hip joint and the precise control of single joints. Further research and optimization are needed. [Extracted from the article]

Discusses the reason why Maui, Hawaii, does not have a business newspaper. Economic conditions; Lack of atmosphere to do work in the island.

Focuses on the potichomania business of John Derian in New York City. Collection of old paper to create decorative accessories; Price of accessories sold; Number of stores open nationwide.

The article enumerates ways on how to practice sustainability in a business. It recommends the use of recycled paper as well as lighter weight paper. Using software and regular updates will improve address quality. Optimizing the use of distributed processing facilities may reduce transportation impacts. Also noted is that overall energy usage can be reduced by virtualizing servers in data centers.

Reviews business and investment news from the week ending February 26, 2000, and looks at the week ahead. Participation of General Motors, Ford Motor and DaimlerChrysler in a joint online purchasing system; Resignation of Aetna Chairman, Chief Executive and President Richard L. Huber; Consolidation in the paper industry; Alcatel SA's planned acquisition of Newbridge Networks; Other items. INSET: Shakespearean Drama Plays Out on Yahoo's Pages.

A new editorial paper published in Oncotarget discusses acute myeloid leukemia (AML), a type of aggressive cancer. The paper highlights recent advancements in understanding AML biology and the potential for developing novel drug therapies. The researchers suggest exploring reductive carboxylation as a possible drug target to weaken tumor cell survival mechanisms and improve patient outcomes. The paper provides further information on this topic and can be accessed through the provided DOI link. [Extracted from the article]

A patent has been issued for an image forming apparatus by Canon Kabushiki Kaisha. The patent describes a configuration that notifies the user of the position of a recording medium remaining in the apparatus. The invention includes a conveyance unit with sensors and light sources that determine the position of a paper jam and control the corresponding light source to turn on. The apparatus also includes a capacitor to reduce voltage fluctuation and a shut-off mechanism when the conveyance unit is pulled out. The invention aims to provide a less expensive configuration for notifying paper jams in an image forming apparatus. [Extracted from the article]

A recent editorial paper published in Oncotarget discusses the therapeutic potential and challenges of cytostatic persister cancer cells. These cells are able to remain viable despite treatment and can contribute to residual diseases and the emergence of resistant clones and relapses. Unlike resistant cells, persister cancer cells enter a non-proliferating state that is reversible upon treatment discontinuation. The paper highlights the need to understand the properties of cytostatic persisters and explores strategies for targeting them to reduce cancer recurrence. The researchers suggest that administering multiple targeted regimens may be necessary to effectively deplete the persister reservoirs in patients undergoing cancer treatments. [Extracted from the article]

Brondell, a leading manufacturer of bidets in North America, has announced the consolidation of Omigo, a direct-to-consumer bidet startup. Brondell plans to leverage its retailer partnerships to launch Omigo into the mass market, expanding its customer reach and reducing the environmental impact of toilet paper. Brondell is committed to sustainability and is a 1% for the Planet product partner, donating one percent of sales on partnership products to environmental nonprofits. The consolidation of Brondell and Omigo aims to make bidets the standard in North American bathrooms and reduce toilet paper waste. [Extracted from the article]

A recent editorial paper published in Oncotarget discusses the molecular functions of regulatory genetic variants associated with cancer. The paper highlights the challenges in understanding the effects of genetic variants, such as their small effect size and their location in non-protein-coding regions of the genome. The researchers propose integrating genomic, epigenomic, transcriptomic, and machine learning methods to identify functional genetic variants and characterize their mode of action in regulating target genes. This approach has implications for cancer research and precision medicine. [Extracted from the article]

Renuvion, developed by Apyx Medical Corporation, has been named the #1 trusted body contouring technology by doctors in an independent survey. Renuvion is a novel technology that targets loose skin, providing effective and unparalleled results for body contouring procedures. It is the first and only body contouring technology that focuses on precision, safety, and results, backed by numerous clinical papers and peer-reviewed studies. Renuvion has gained popularity among plastic surgeons globally and has been used by over 350,000 patients to transform their physical, mental, and emotional well-being. Additionally, 4 out of 5 surgeons prefer Renuvion over other treatments to follow liposuction, making it a proven solution for loose skin. [Extracted from the article]

A research paper titled "Association between osteoporosis and the rate of telomere shortening" was published in Aging, exploring the potential link between osteoporosis and leukocyte telomere length (LTL) shortening. The study involved researchers from various institutions who aimed to determine if osteoporosis is independently associated with LTL shortening in a prospective longitudinal cohort. The results of the study indicated that osteoporosis was indeed independently associated with rapid LTL shortening over a 2-year period. This research adds to the ongoing discussion surrounding the association between LTL and osteoporosis. [Extracted from the article]

A new editorial paper published in Oncotarget's Volume 15 discusses the research conducted by Justine Paris and Guilhem Bousquet on dealing with runaway metastatic disease. The researchers found that PROM2 is a predictive biomarker of distant metastases and shorter survival in patients with stage III melanomas. They also demonstrated that PROM2 overexpression is closely linked to the runaway metastatic process through the increase of epithelial-to-mesenchymal transition marker expression and ferroptosis resistance. These findings have been confirmed in renal and breast cancers, and the researchers successfully implemented an original in vivo model of metastatic runaway. [Extracted from the article]

A research paper titled "Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma" was recently published in Oncotarget's Volume 15. The study, conducted by researchers from Yale University, Oregon Health and Science University, Cancer Early Detection Advanced Research Center, and the Department of Veterans Affairs Portland Health Care System, aimed to evaluate the gene expression of MIF, DDT, and relevant pathway markers in relation to clinical outcomes in melanoma patients. The findings suggest that MIF and DDT may play a role in tumor progression and could be potential therapeutic targets in immune checkpoint inhibition-resistant melanomas. The study also highlights the potential of CD74:MIF and CD74:DDT expression ratio measurements as prognostic markers for survival outcomes and immune checkpoint inhibition response in melanoma patients. [Extracted from the article]