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2 results on '"clade 2.3.4"'

1. Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China

Author

Hongquan Wan, Lei Zhong, Min Gu, Xiufan Liu, Wang Xiaoquan, Daxin Peng, Huimou Liu, Guo Zhao, Junqing Huang, Kunkun Zhao, and Wenbo Liu

Subjects
Microbiology (medical), clade 2.3.4, China, Genotype, Epidemiology, Highly pathogenic, highly pathogenic, lcsh:Medicine, Hemagglutinin Glycoproteins, Influenza Virus, HPAI, avian influenza virus, Biology, medicine.disease_cause, phylogeny, H5N1 genetic structure, Antigenic drift, Poultry, influenza virus, lcsh:Infectious and parasitic diseases, Phylogenetics, medicine, Influenza A virus, Animals, viruses, lcsh:RC109-216, Clade, Poultry Diseases, AIV, flu, Influenza A Virus, H5N1 Subtype, clade, avian, lcsh:R, Dispatch, virus diseases, H5N1, Virology, Influenza A virus subtype H5N1, Infectious Diseases, H5, birds, Influenza in Birds, chickens, influenza
Abstract

We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009–2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to control these viruses in poultry.

Published
2013

2. Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant

Author

de Vries, Erik, Guo, Hongbo, Dai, Meiling, Rottier, Peter J M, van Kuppeveld, Frank J M, de Haan, Cornelis A M, LS Virologie, dI&I I&I-1, LS Virologie, and dI&I I&I-1

Subjects
Epidemiology, highly pathogenic, lcsh:Medicine, HPAI, rapid emergence, medicine.disease_cause, Poultry, Disease Outbreaks, Monophyly, reassortment events, Influenza A virus, Clade, Phylogeny, Dispatch, virus diseases, H5N1, virulent, Infectious Diseases, Hemagglutinins, reassortant, influenza, Reassortant Viruses, monophyletic group, Microbiology (medical), clade 2.3.4, Genotype, Hemagglutinin (influenza), Biology, H5N1 genetic structure, lcsh:Infectious and parasitic diseases, subtype, Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant, Phylogenetics, Influenza, Human, evolution, medicine, Animals, Humans, viruses, lcsh:RC109-216, hemagglutinin, Influenza A Virus, H5N1 Subtype, lcsh:R, Genetic Variation, Virology, Influenza A virus subtype H5N1, variant, Influenza in Birds, biology.protein, avian influenza
Abstract

In 2014, novel highly pathogenic avian influenza A H5N2, H5N5, H5N6, and H5N8 viruses caused outbreaks in Asia, Europe, and North America. The H5 genes of these viruses form a monophyletic group that evolved from a clade 2.3.4 H5N1 variant. This rapid emergence of new H5Nx combinations is unprecedented in the H5N1 evolutionary history.

Published
2015

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