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Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China

Authors :
Hongquan Wan
Lei Zhong
Min Gu
Xiufan Liu
Wang Xiaoquan
Daxin Peng
Huimou Liu
Guo Zhao
Junqing Huang
Kunkun Zhao
Wenbo Liu
Source :
Emerging Infectious Diseases, Vol 19, Iss 12, Pp 2021-2024 (2013), Emerging Infectious Diseases
Publication Year :
2013
Publisher :
Centers for Disease Control and Prevention, 2013.

Abstract

We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009–2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to control these viruses in poultry.

Details

Language :
English
ISSN :
10806059 and 10806040
Volume :
19
Issue :
12
Database :
OpenAIRE
Journal :
Emerging Infectious Diseases
Accession number :
edsair.doi.dedup.....c10ec43d359a2e2e04cb6556d856c52f