1. Large-Scale Synthesis of Eldecalcitol
- Author
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Jung Jaehun, Hae Sol Kim, Chang Hun Seol, Seung Jong Lee, Kee-Young Lee, In A Jung, Seong Hu Park, Won Taek Lee, Hyung Wook Moon, Seon Mi Lee, Hyunik Shin, Bogonda Gangganna, Ji Soo Heo, Areum Baek, Kim Seung Woo, Chang-Young Oh, Jung Se Gyo, Juyoung Song, Seok-Hwi Park, and Kang Hee Lee
- Subjects
Sharpless epoxidation ,chemistry.chemical_compound ,chemistry ,Scale (ratio) ,Stereochemistry ,Organic Chemistry ,Epoxide ,Physical and Theoretical Chemistry ,Eldecalcitol - Abstract
Industrial-scale synthesis of eldecalcitol is described. AA highly diastereoselective epoxidation of p-methoxybenzyl (PMB) protected dienol at room temperature provides the key epoxide intermediate...
- Published
- 2020