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1. Aplicación web de puntos de interés geolocalizados

Author

González Herrero, Eva María, Díaz Gómez, Fernando, Universidad de Valladolid. Escuela de Ingeniería Informática de Segovia, González Herrero, Eva María, Díaz Gómez, Fernando, and Universidad de Valladolid. Escuela de Ingeniería Informática de Segovia

Abstract

Dado que en la vida moderna la mayoría de los trabajos requieren de estar sentado en una oficina, hacen muy difícil disfrutar del aire libre y de lugares de ocio fuera de nuestro ambiente doméstico. Con esta aplicación, se busca fomentar que las personas incorporen a su vida nuevas formas de disfrutar de diversas experiencias recreativas, ya sea jugar en un billar, tomar una cerveza en un bar, visitar un museo o explorar nuevos paisajes. El objetivo es crear una aplicación web que permita gestionar puntos de interés, tanto urbanos como rurales, y que ofrezca a los usuarios la posibilidad de marcar sus lugares favoritos. Los usuarios podrán subir fotos de los lugares visitados y añadir una descripción, creando así una comunidad de recomendaciones y experiencias compartidas., Grado en Ingeniería Informática de Servicios y Aplicaciones

Published
2024

2. Projecte de Millora Emociona't

Author

Hernández Pérez, Marta, Magaña Herrero, Eva, Hernández Pérez, Marta, and Magaña Herrero, Eva

Published
2023

3. Adolescentes y redes: propuesta de intervención en educación inclusiva

Author

Fernández Herrero, Eva, Gutiérrez Pequeño, José Miguel, Universidad de Valladolid. Facultad de Educación de Palencia, Fernández Herrero, Eva, Gutiérrez Pequeño, José Miguel, and Universidad de Valladolid. Facultad de Educación de Palencia

Abstract

Las tecnologías y, sobre todo las redes sociales, se han convertido en una herramienta indispensable en nuestro día a día. Fundamentalmente para la comunicación y creación de vínculos sociales. Por ello, es de vital importancia aprender a usar y enseñar sobre el uso de estas, sobre todo a la población adolescente, quien hace un mayor uso de ellas. Es indispensable enseñar los diferentes usos que se puede dar a las redes sociales y las TICS, siempre desde la responsabilidad que esto conlleva. El siguiente Trabajo de Fin de Grado presenta una propuesta de intervención con menores en riesgo de exclusión social dentro del ámbito educativo, llevada a cabo a través del uso de las redes sociales y desde el punto de vista de la Educación Social. Pues con este trabajo se pretende la introducción del uso de las redes en el aula para utilizarlo como una herramienta inclusiva, lo que da otra perspectiva a la educación, Grado en Educación Social

Published
2022

4. Adolescentes y redes: propuesta de intervención en educación inclusiva

Author

Fernández Herrero, Eva, Gutiérrez Pequeño, José Miguel, Universidad de Valladolid. Facultad de Educación de Palencia, Fernández Herrero, Eva, Gutiérrez Pequeño, José Miguel, and Universidad de Valladolid. Facultad de Educación de Palencia

Abstract

Las tecnologías y, sobre todo las redes sociales, se han convertido en una herramienta indispensable en nuestro día a día. Fundamentalmente para la comunicación y creación de vínculos sociales. Por ello, es de vital importancia aprender a usar y enseñar sobre el uso de estas, sobre todo a la población adolescente, quien hace un mayor uso de ellas. Es indispensable enseñar los diferentes usos que se puede dar a las redes sociales y las TICS, siempre desde la responsabilidad que esto conlleva. El siguiente Trabajo de Fin de Grado presenta una propuesta de intervención con menores en riesgo de exclusión social dentro del ámbito educativo, llevada a cabo a través del uso de las redes sociales y desde el punto de vista de la Educación Social. Pues con este trabajo se pretende la introducción del uso de las redes en el aula para utilizarlo como una herramienta inclusiva, lo que da otra perspectiva a la educación, Grado en Educación Social

Published
2022

5. Adolescentes y redes: propuesta de intervención en educación inclusiva

Author

Fernández Herrero, Eva, Gutiérrez Pequeño, José Miguel, Universidad de Valladolid. Facultad de Educación de Palencia, Fernández Herrero, Eva, Gutiérrez Pequeño, José Miguel, and Universidad de Valladolid. Facultad de Educación de Palencia

Abstract

Las tecnologías y, sobre todo las redes sociales, se han convertido en una herramienta indispensable en nuestro día a día. Fundamentalmente para la comunicación y creación de vínculos sociales. Por ello, es de vital importancia aprender a usar y enseñar sobre el uso de estas, sobre todo a la población adolescente, quien hace un mayor uso de ellas. Es indispensable enseñar los diferentes usos que se puede dar a las redes sociales y las TICS, siempre desde la responsabilidad que esto conlleva. El siguiente Trabajo de Fin de Grado presenta una propuesta de intervención con menores en riesgo de exclusión social dentro del ámbito educativo, llevada a cabo a través del uso de las redes sociales y desde el punto de vista de la Educación Social. Pues con este trabajo se pretende la introducción del uso de las redes en el aula para utilizarlo como una herramienta inclusiva, lo que da otra perspectiva a la educación, Grado en Educación Social

Published
2022

6. Ventilation practices in burn patients-an international prospective observational cohort study.

Author

Schultz, Marcus J, Schultz, Marcus J, Horn, Janneke, Hollmann, Markus W, Preckel, Benedikt, Glas, Gerie J, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M, Cleffken, Berry, Juffermans, Nicole P, Knape, Paul, Loef, Bert G, Mackie, David P, Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Glas, Gerie, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Manoel Silva Junior, João, Grion, Cintia MC, Jeschke, Marc G, Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Asehoune, Karim, Floch, Renan Le, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maïté, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C, Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Bouza, Maria Teresa, Agrifoglio, Alexander, Fredén, Filip, Palmieri, Tina, Painting, Lynda E, LAMiNAR investigators, Schultz, Marcus J, Schultz, Marcus J, Horn, Janneke, Hollmann, Markus W, Preckel, Benedikt, Glas, Gerie J, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M, Cleffken, Berry, Juffermans, Nicole P, Knape, Paul, Loef, Bert G, Mackie, David P, Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Glas, Gerie, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Manoel Silva Junior, João, Grion, Cintia MC, Jeschke, Marc G, Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Asehoune, Karim, Floch, Renan Le, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maïté, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C, Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Bouza, Maria Teresa, Agrifoglio, Alexander, Fredén, Filip, Palmieri, Tina, Painting, Lynda E, and LAMiNAR investigators

Abstract

BackgroundIt is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28).MethodsThis is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V T) was defined as V T ≤ 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma.ResultsA total of 160 patients from 28 ICUs in 16 countries were included. Low V T was used in 74% of patients, median V T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p = 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V T (p = 0.98). All patients were ventilated with PEEP levels ≥5 cmH2O; 80% of patients had maximum airway pressures <30 cmH2O.ConclusionIn this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V T was not associated with a reduction in VFD-28.Trial registrationClinicaltrials.gov NCT02312869. Date of registration: 9 December 2014.

Published
2021

7. Ventilation practices in burn patients-an international prospective observational cohort study

Author

Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., Schultz, Marcus J., Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.

Abstract

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T <= 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V-T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma. Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low V-T was used in 74% of patients, median V-T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p= 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V-T (p= 0.98). All patients were ventilated with PEEP levels >= 5 cmH(2)O; 80% of patients had maximum airway pressures <30 cmH(2)O. Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V-T was not associated with a reduction in VFD-28.

Published
2021
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8. Ventilation practices in burn patients-an international prospective observational cohort study

Author

Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., Schultz, Marcus J., Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.

Abstract

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T <= 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V-T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma. Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low V-T was used in 74% of patients, median V-T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p= 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V-T (p= 0.98). All patients were ventilated with PEEP levels >= 5 cmH(2)O; 80% of patients had maximum airway pressures <30 cmH(2)O. Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V-T was not associated with a reduction in VFD-28., Funding Agencies|Nederlandse Brandwonden Stichting (the Dutch Burn Association, Beverwijk, The Netherlands)Netherlands Government

Published
2021
Full Text
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9. Ventilation practices in burn patients-an international prospective observational cohort study

Author

Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., Schultz, Marcus J., Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.

Abstract

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T <= 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V-T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma. Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low V-T was used in 74% of patients, median V-T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p= 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V-T (p= 0.98). All patients were ventilated with PEEP levels >= 5 cmH(2)O; 80% of patients had maximum airway pressures <30 cmH(2)O. Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V-T was not associated with a reduction in VFD-28.

Published
2021
Full Text
View/download PDF

10. Ventilation practices in burn patients-an international prospective observational cohort study

Author

Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., Schultz, Marcus J., Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.

Abstract

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T <= 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V-T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma. Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low V-T was used in 74% of patients, median V-T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p= 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V-T (p= 0.98). All patients were ventilated with PEEP levels >= 5 cmH(2)O; 80% of patients had maximum airway pressures <30 cmH(2)O. Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V-T was not associated with a reduction in VFD-28., Funding Agencies|Nederlandse Brandwonden Stichting (the Dutch Burn Association, Beverwijk, The Netherlands)Netherlands Government

Published
2021
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11. Ventilation practices in burn patients-an international prospective observational cohort study

Author

Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., Schultz, Marcus J., Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.

Abstract

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T <= 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V-T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma. Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low V-T was used in 74% of patients, median V-T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p= 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V-T (p= 0.98). All patients were ventilated with PEEP levels >= 5 cmH(2)O; 80% of patients had maximum airway pressures <30 cmH(2)O. Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V-T was not associated with a reduction in VFD-28.

Published
2021
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12. Ventilation practices in burn patients-an international prospective observational cohort study.

Author

Schultz, Marcus J, Schultz, Marcus J, Horn, Janneke, Hollmann, Markus W, Preckel, Benedikt, Glas, Gerie J, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M, Cleffken, Berry, Juffermans, Nicole P, Knape, Paul, Loef, Bert G, Mackie, David P, Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Glas, Gerie, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Manoel Silva Junior, João, Grion, Cintia MC, Jeschke, Marc G, Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Asehoune, Karim, Floch, Renan Le, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maïté, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C, Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Bouza, Maria Teresa, Agrifoglio, Alexander, Fredén, Filip, Palmieri, Tina, Painting, Lynda E, LAMiNAR investigators, Schultz, Marcus J, Schultz, Marcus J, Horn, Janneke, Hollmann, Markus W, Preckel, Benedikt, Glas, Gerie J, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M, Cleffken, Berry, Juffermans, Nicole P, Knape, Paul, Loef, Bert G, Mackie, David P, Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Glas, Gerie, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Manoel Silva Junior, João, Grion, Cintia MC, Jeschke, Marc G, Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Asehoune, Karim, Floch, Renan Le, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maïté, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C, Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Bouza, Maria Teresa, Agrifoglio, Alexander, Fredén, Filip, Palmieri, Tina, Painting, Lynda E, and LAMiNAR investigators

Abstract

BackgroundIt is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28).MethodsThis is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V T) was defined as V T ≤ 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma.ResultsA total of 160 patients from 28 ICUs in 16 countries were included. Low V T was used in 74% of patients, median V T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p = 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V T (p = 0.98). All patients were ventilated with PEEP levels ≥5 cmH2O; 80% of patients had maximum airway pressures <30 cmH2O.ConclusionIn this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V T was not associated with a reduction in VFD-28.Trial registrationClinicaltrials.gov NCT02312869. Date of registration: 9 December 2014.

Published
2021

13. Ventilation practices in burn patients-an international prospective observational cohort study

Author

Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., Schultz, Marcus J., Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.

Abstract

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T <= 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V-T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma. Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low V-T was used in 74% of patients, median V-T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p= 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V-T (p= 0.98). All patients were ventilated with PEEP levels >= 5 cmH(2)O; 80% of patients had maximum airway pressures <30 cmH(2)O. Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V-T was not associated with a reduction in VFD-28.

Published
2021
Full Text
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14. Ventilation practices in burn patients-an international prospective observational cohort study

Author

Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., Schultz, Marcus J., Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.

Abstract

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T <= 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V-T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma. Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low V-T was used in 74% of patients, median V-T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p= 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V-T (p= 0.98). All patients were ventilated with PEEP levels >= 5 cmH(2)O; 80% of patients had maximum airway pressures <30 cmH(2)O. Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V-T was not associated with a reduction in VFD-28., Funding Agencies|Nederlandse Brandwonden Stichting (the Dutch Burn Association, Beverwijk, The Netherlands)Netherlands Government

Published
2021
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15. Ventilation practices in burn patients-an international prospective observational cohort study

Author

Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., Schultz, Marcus J., Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.

Abstract

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T <= 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V-T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma. Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low V-T was used in 74% of patients, median V-T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p= 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V-T (p= 0.98). All patients were ventilated with PEEP levels >= 5 cmH(2)O; 80% of patients had maximum airway pressures <30 cmH(2)O. Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V-T was not associated with a reduction in VFD-28., Funding Agencies|Nederlandse Brandwonden Stichting (the Dutch Burn Association, Beverwijk, The Netherlands)Netherlands Government

Published
2021
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16. Ventilation practices in burn patients-an international prospective observational cohort study

Author

Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., Schultz, Marcus J., Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.

Abstract

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T <= 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V-T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma. Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low V-T was used in 74% of patients, median V-T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p= 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V-T (p= 0.98). All patients were ventilated with PEEP levels >= 5 cmH(2)O; 80% of patients had maximum airway pressures <30 cmH(2)O. Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V-T was not associated with a reduction in VFD-28., Funding Agencies|Nederlandse Brandwonden Stichting (the Dutch Burn Association, Beverwijk, The Netherlands)Netherlands Government

Published
2021
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17. Ventilation practices in burn patients-an international prospective observational cohort study

Author

Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., Schultz, Marcus J., Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.

Abstract

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T <= 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V-T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma. Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low V-T was used in 74% of patients, median V-T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p= 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V-T (p= 0.98). All patients were ventilated with PEEP levels >= 5 cmH(2)O; 80% of patients had maximum airway pressures <30 cmH(2)O. Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low V-T was not associated with a reduction in VFD-28.

Published
2021
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18. En los desvanes de la ficcionalidad: los diarios de Trapiello

Author

García Rodríguez, Javier (null), Miranda Herrero, Eva María, García Rodríguez, Javier (null), and Miranda Herrero, Eva María

Abstract

En 1990 aparecía el primer volumen del Salón de Pasos Perdidos de Andrés Trapiello. Desde entonces, se han publicado una veintena de tomos de esta serie personal, que en palabras del autor, gozan de una doble naturaleza de diario y novela, porque se escriben a partir de una serie de notas anuales manuscritas en cuadernos de hule negro que se dejan madurar en el tiempo para ser reelaborados con posterioridad y publicados como “novela en marcha”. Este carácter híbrido los ha convertido en una muestra de diario literario autoficcional en los márgenes de la literariedad; lo que nos conduce a un cuestionamiento necesario de la teoría genérica. De hecho, no son pocas las voces como la de Pozuelo Yvancos que reivindican la necesidad de incluir dentro del sistema de géneros las llamadas literaturas del yo, debido a su intencionalidad estética más allá de la ficcionalidad. Esto nos lleva a realizar en la parte general un repaso de la evolución del sistema genérico de la mano de los estudios de Huerta Calvo, en su intento sistematizador de los géneros no ficcionales, para pasar después a ver la evolución del diario en relación otras literaturas del yo a través de una tipología que parte de los estudios de Caballé, Romera Castillo y Puertas Moya. Así podremos comprender mejor la evolución de este género histórico del se ofrece también una clasificación y un repaso de sus principales características formales, comunicativas y pragmáticas a partir de la aplicación de las teorías de George May en su similitud y diferenciación con la autobiografía para reivindicar una mayor autonomía del diario que permita distinguir diarios ficcionales, autoficcionales y no ficcionales, sin necesidad de acudir a la novela como corpus que agrupe a los dos primeros casos. Esto no es impedimento para reconocer la mezcla genérica en casos como los diarios de Trapiello, autor que ha llevado al género a su máximo esplendor. Los diarios han sido incluidos como obra paradigmática del continuum de los días

Published
2017

19. Treatment of swine manure: case studies in European’s N-surplus areas

Author

European Commission, García-González, María Cruz, Riaño Berta, Maria Teresa, Herrero, Eva, Ward, Alastair James, Provolo, G., Moscatelli, Giuseppe, Piccinini, Sergio, Bonmatí, August, Bernal Calderón, M. Pilar, Wiśniewska, Hanna, Proniewicz, Marcin, European Commission, García-González, María Cruz, Riaño Berta, Maria Teresa, Herrero, Eva, Ward, Alastair James, Provolo, G., Moscatelli, Giuseppe, Piccinini, Sergio, Bonmatí, August, Bernal Calderón, M. Pilar, Wiśniewska, Hanna, and Proniewicz, Marcin

Abstract

In this study, eight different manure treatment plants were monitored. The plants were four on-farm and four centralized treatment plants, all of them at full-scale level. Assessment includes a total of seven pre-treatment and process units as follows: mechanical separation, with and without coagulant and flocculant addition, pasteurization, nitrification-denitrification, anaerobic digestion, and composting. The plants are located in nutrient surplus areas of three European Member States (Spain, Italy and Denmark), the majority of these areas being Nitrate Vulnerable Zones (NVZ). Results presented herein are data collected over a six-month period and comprise performance data of the treatment plants, pathogen indicators (E.coli and Salmonella) and greenhouse gas (GHG) emissions data under two scenarios: 1) the baseline scenario and 2) the treatment plant scenario. The assessment includes GHG emissions of the storage facilities, transportation, and subsequent intermediate storage, electric consumption, electric production, composting, and land application. All treatment plants studied generated a significant reduction in GHG emissions (between 53 and 90 %) in comparison to the baseline scenario. Organic matter and total solids (TS) content in manure were also greatly reduced, with values ranging between 35-53 % of chemical oxygen demand (COD) and, 24-61 % of TS for anaerobic digestion (AD) treatment plants, 77-93 % COD and 70 % TS in the case of AD combined with nitrogen (N)-removal unit plants. Nitrogen concentrations were also greatly reduced (between 65-85 %) total Kjeldahl nitrogen (TKN) and 68-83 % ammonium (NH4+-N)) in plants with N-removal units.

Published
2016

20. Evaluación de sistemas de gestión de estiércol en Europa

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Universitat Politècnica de Catalunya. GREA - Grup de Recerca d'Enginyeria Agro-Ambiental, Teresa Fernández, Marta, Herrero Mallén, Eva, Bescós Roy, Berta, Bernal, M. Pilar, Bescós, Berta, Burgos, Laura, Bustamante, M. Ángeles, Clemente, Rafael, Fabbri, Claudio, Flotats Ripoll, Xavier, García-González, Maria Cruz, Herrero, Eva, Mattachini, Gabriele, Moscatelli, Giuseppe, Noguerol Arias, Joan, Palatsi Civit, Jordi, Piccinini, Sergio, Proniewicz, Marcin, Provolo, Giorgio, Riaño, Berta, Riau Arenas, Victor, Sáez, José A., Tey, Laura, Torrellas, Marta, Valli, Laura, Ward, Alastair James, Wisniewska, Hanna, Bonmatí Blasi, August, Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Universitat Politècnica de Catalunya. GREA - Grup de Recerca d'Enginyeria Agro-Ambiental, Teresa Fernández, Marta, Herrero Mallén, Eva, Bescós Roy, Berta, Bernal, M. Pilar, Bescós, Berta, Burgos, Laura, Bustamante, M. Ángeles, Clemente, Rafael, Fabbri, Claudio, Flotats Ripoll, Xavier, García-González, Maria Cruz, Herrero, Eva, Mattachini, Gabriele, Moscatelli, Giuseppe, Noguerol Arias, Joan, Palatsi Civit, Jordi, Piccinini, Sergio, Proniewicz, Marcin, Provolo, Giorgio, Riaño, Berta, Riau Arenas, Victor, Sáez, José A., Tey, Laura, Torrellas, Marta, Valli, Laura, Ward, Alastair James, Wisniewska, Hanna, and Bonmatí Blasi, August

Abstract

La ganadería en Europa genera 1.400 millones de toneladas de estiércol al año; para poder hacernos una idea, con esta cantidad, se podrían llenar más de 650 millones de piscinas olímpicas, Postprint (published version)

Published
2015

21. EARLY FLOWERING4 Recruitment of EARLY FLOWERING3 in the Nucleus Sustains the Arabidopsis Circadian Clock

Author

Herrero, Eva, Kolmos, Elsebeth, Bujdoso, Nora, Yuan, Ye, Wang, Mengmeng, Berns, Markus, Uhlworm, Heike, Coupland, George, Saini, Reena, Jaskolski, Mariusz, Webb, Alex, Goncalves, Jorge, Davis, Seth, Herrero, Eva, Kolmos, Elsebeth, Bujdoso, Nora, Yuan, Ye, Wang, Mengmeng, Berns, Markus, Uhlworm, Heike, Coupland, George, Saini, Reena, Jaskolski, Mariusz, Webb, Alex, Goncalves, Jorge, and Davis, Seth

Abstract

The plant circadian clock is proposed to be a network of several interconnected feedback loops, and loss of any component leads to changes in oscillator speed. We previously reported that Arabidopsis thaliana EARLY FLOWERING4 (ELF4) is required to sustain this oscillator and that the elf4 mutant is arrhythmic. This phenotype is shared with both elf3 and lux. Here, we show that overexpression of either ELF3 or LUX ARRHYTHMO (LUX) complements the elf4 mutant phenotype. Furthermore, ELF4 causes ELF3 to form foci in the nucleus. We used expression data to direct a mathematical position of ELF3 in the clock network. This revealed direct effects on the morning clock gene PRR9, and we determined association of ELF3 to a conserved region of the PRR9 promoter. A cis-element in this region was suggestive of ELF3 recruitment by the transcription factor LUX, consistent with both ELF3 and LUX acting genetically downstream of ELF4. Taken together, using integrated approaches, we identified ELF4/ELF3 together with LUX to be pivotal for sustenance of plant circadian rhythms.

Published
2012

22. Arabidopsis thaliana transcription factors bZIP19 and bZIP23 regulate the adaptation to zinc deficiency

Author

Assuncao, Ana Goncalves Leite, Herrero, Eva, Lin, Ya-Fen, Huettel, Bruno, Talukdar, Sangita, Smaczniak, Cezary, G.H. Immink, Richard, Eldik, Mandy van, Fiers, Mark, Schat, Henk, Aarts, Mark G.M., Assuncao, Ana Goncalves Leite, Herrero, Eva, Lin, Ya-Fen, Huettel, Bruno, Talukdar, Sangita, Smaczniak, Cezary, G.H. Immink, Richard, Eldik, Mandy van, Fiers, Mark, Schat, Henk, and Aarts, Mark G.M.

Published
2010

23. Arabidopsis thaliana transcription factors bZIP19 and bZIP23 regulate the adaptation to zinc deficiency

Author

Assuncao, Ana Goncalves Leite, Herrero, Eva, Lin, Ya-Fen, Huettel, Bruno, Talukdar, Sangita, Smaczniak, Cezary, G.H. Immink, Richard, Eldik, Mandy van, Fiers, Mark, Schat, Henk, Aarts, Mark G.M., Assuncao, Ana Goncalves Leite, Herrero, Eva, Lin, Ya-Fen, Huettel, Bruno, Talukdar, Sangita, Smaczniak, Cezary, G.H. Immink, Richard, Eldik, Mandy van, Fiers, Mark, Schat, Henk, and Aarts, Mark G.M.

Published
2010

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