38 results on '"Vieten, Cassandra"'
Search Results
2. Enhancing training in spiritual and religious competencies in mental health graduate education: Evaluation of an integrated curricular approach.
- Author
-
Pearce MJ, Pargament KI, Wong S, Hinkel H, Salcone S, Morgan G, Kemp D, Brock B, Kim E, Oxhandler HK, Vieten C, Fox J, Polson EC, and Currier JM
- Subjects
- Humans, Female, Male, Adult, Young Adult, Curriculum, Spirituality, Education, Graduate methods, Mental Health
- Abstract
Despite practice guidelines for multiculturally competent care, including spiritual/religious diversity, most mental health graduate training programs do not formally address spiritual/religious competencies. Thus, we enhanced the Spiritual Competency Training in Mental Health (SCT-MH) course curriculum to train graduate students in foundational attitudes, knowledge, and skills for addressing clients' spirituality and/or religion (S/R). The hybrid (online and in-person) SCT-MH course curriculum was integrated into existing required graduate clinical courses (replacing 15% of a course's curriculum) and taught to 309 students by 20 instructors in 20 different graduate training programs across counseling, psychology, and social work disciplines. Using a multiple baseline waitlist control design in which students served as their own controls, students completed validated assessments at three timepoints evaluating their spiritual/religious competencies for understanding the intersection between S/R and mental health. We also collected qualitative data from the students to evaluate acceptability of the content and format of the training program. Students' scores on all seven measures of spiritual/religious competencies had a statistically significant positive increase after engaging with the SCT-MH curriculum compared to the control period. At the end of the course, 97% of the students envisioned using spiritually integrated therapy techniques with their clients at least some of the time, 92% or more rated the materials as helpful and relevant, and 96% were satisfied with the training modules. Results demonstrate that dedicating a small (i.e., 6 hours of class time; 10 hours outside class time) but intentional amount of course time to teaching spiritual/religious competencies increases students' attitudes, knowledge, and skills for attending to clients' S/R in clinical practice. The SCT-MH hybrid course content is freely available to all graduate programs on our website. https://www.spiritualandreligiouscompetenciesproject.com/resources/sct-mh., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Pearce et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
- Published
- 2024
- Full Text
- View/download PDF
3. Helpful and Harmful Approaches to Integrating Religion and Spirituality into Mental Health Care: A National Survey of Current Clients' Experiences in the United States.
- Author
-
Oxhandler HK, Polson EC, Ander G, Moffatt KM, Pearce M, Vieten C, and Pargament KI
- Subjects
- Humans, United States, Female, Male, Adult, Middle Aged, Surveys and Questionnaires, Young Adult, Aged, Adolescent, Spirituality, Mental Health Services, Mental Disorders therapy, Mental Disorders psychology
- Abstract
This article describes a national sample of 989 current mental health clients' views regarding whether and how their mental health care providers integrated the client's religion/spirituality (RS) into treatment. Within the online Qualtrics survey, two open-ended items asked respondents what (if anything) the client perceived their therapist having done regarding the client's RS that was (1) helpful/supportive or (2) hurtful/harmful. Participants also reported various ways therapists included the topic of RS in practice, if any. Nearly half freely described helpful ways their providers integrated the client's RS, and half indicated it was not discussed or applicable. Although 9.6% described hurtful experiences, most indicated their provider had not done anything harmful related to integrating RS. Implications for practice and training across mental health disciplines are discussed., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Published
- 2024
- Full Text
- View/download PDF
4. Measures of empathy and compassion: A scoping review.
- Author
-
Vieten C, Rubanovich CK, Khatib L, Sprengel M, Tanega C, Polizzi C, Vahidi P, Malaktaris A, Chu G, Lang AJ, Tai-Seale M, Eyler L, and Bloss C
- Subjects
- Psychometrics, Empathy, Mindfulness
- Abstract
Evidence to date indicates that compassion and empathy are health-enhancing qualities. Research points to interventions and practices involving compassion and empathy being beneficial, as well as being salient outcomes of contemplative practices such as mindfulness. Advancing the science of compassion and empathy requires that we select measures best suited to evaluating effectiveness of training and answering research questions. The objective of this scoping review was to 1) determine what instruments are currently available for measuring empathy and compassion, 2) assess how and to what extent they have been validated, and 3) provide an online tool to assist researchers and program evaluators in selecting appropriate measures for their settings and populations. A scoping review and broad evidence map were employed to systematically search and present an overview of the large and diverse body of literature pertaining to measuring compassion and empathy. A search string yielded 19,446 articles, and screening resulted in 559 measure development or validation articles reporting on 503 measures focusing on or containing subscales designed to measure empathy and/or compassion. For each measure, we identified the type of measure, construct being measured, in what context or population it was validated, response set, sample items, and how many different types of psychometrics had been assessed for that measure. We provide tables summarizing these data, as well as an open-source online interactive data visualization allowing viewers to search for measures of empathy and compassion, review their basic qualities, and access original citations containing more detail. Finally, we provide a rubric to help readers determine which measure(s) might best fit their context., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Vieten et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
- Published
- 2024
- Full Text
- View/download PDF
5. Mental health professionals' perspectives on the relevance of religion and spirituality to mental health care.
- Author
-
Vieten C, Oxhandler HK, Pearce M, Fry N, Tanega C, and Pargament K
- Subjects
- Humans, Religion, Health Personnel psychology, Cultural Diversity, Spirituality, Mental Health
- Abstract
Background: A large body of evidence indicates that spiritual and religious backgrounds, beliefs, and practices (SRBBPs) are related to better psychological health. Spirituality and religion (R/S) are also important aspects of multicultural diversity. There is evidence that clients would like to talk about their spirituality, and that including it in assessment and treatment planning can be beneficial. However, the extent to which practicing mental health professionals view SRBBPs as relevant to mental health and clinical practice is unclear., Methods: A survey examining several aspects of addressing SRBBPs in clinical practice was distributed to 894 professionals across mental health disciplines, including psychiatry, psychology, social work, marriage family therapy, licensed professional counselors, certified chemical dependency counselors, and psychiatric mental health nurses., Results: 89% of mental health professionals agreed that clinicians should receive training in R/S competencies. There were no differences between mental health disciplines in ratings of importance of such training. Younger individuals and those who identify as more spiritual were more likely to consider R/S training as important. Although 47.1% of professionals had not received much R/S training, many perceived themselves to be highly competent in R/S clinical integration practices (57.8% considered themselves able to display them very much or completely). In addition, respondents with more R/S training evaluated themselves as more proficient in R/S clinical integration. Nearly two-thirds (65.2%) of respondents reported encountering few to no barriers to engaging in R/S competent mental health care., Conclusions: There is a growing consensus among mental health care professionals that mental health professionals should be trained in R/S competencies. Strong agreement exists that basic R/S competencies include respect, empathy, examination of bias, and routine assessment of R/S in mental health care. Four in five of those surveyed agree that more active competencies, such as identifying and addressing religious and spiritual struggles and problems and helping clients explore and access R/S strengths and resources should be included, whereas one in five report less comfort with these competencies., (© 2023. The Author(s).)
- Published
- 2023
- Full Text
- View/download PDF
6. Enhancing competencies for the ethical integration of religion and spirituality in psychological services.
- Author
-
Currier JM, Fox J, Vieten C, Pearce M, and Oxhandler HK
- Subjects
- Humans, Religion, Health Personnel, Spirituality, Spiritual Therapies
- Abstract
Advancement of Spiritual and religious competencies aligns with increasing attention to the pivotal role of multiculturalism and intersectionality, as well as shifts in organizational values and strategies, that shape the delivery of psychological services (e.g., evidence-based practice). A growing evidence base also attests to ethical integration of peoples' religious faith and/or spirituality (R/S) in their mental care as enhancing the utilization and efficacy of psychological services. When considering the essential attitudes, knowledge, and skills for addressing religious and spiritual aspects of clients' lives, lack of R/S competencies among psychologists and other mental health professionals impedes ethical and effective practice. The purpose of this article is to discuss the following: (a) skills for negotiating ethical challenges with spiritually integrated care; and (b) strategies for assessing a client's R/S. We also describe systemic barriers to ethical integration of R/S in mental health professions and briefly introduce our Spiritual and Religious Competencies project. Looking ahead, a strategic, interdisciplinary, and comprehensive approach is needed to transform the practice of mental health care in a manner that more fully aligns with the values, principles, and expectations across our disciplines' professional ethical codes and accreditation standards. We propose that explicit training across mental health professions is necessary to more fully honor R/S diversity and the importance of this layer of identity and intersectionality in many peoples' lives. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
- Published
- 2023
- Full Text
- View/download PDF
7. Long-term effects of a prenatal mindfulness intervention on depressive symptoms in a diverse sample of women.
- Author
-
Roubinov DS, Epel ES, Coccia M, Coleman-Phox K, Vieten C, Adler NE, Laraia B, and Bush NR
- Subjects
- Pregnancy, Female, Humans, Depression psychology, Pandemics, Parturition psychology, Mindfulness methods, COVID-19
- Abstract
Objective: Depression is a public health crisis, and scalable, affordable interventions are needed. Although many psychosocial interventions are effective, there is little research investigating their sustained, long-term influence on well-being. The purpose of this study was to examine whether a prenatal mindfulness intervention with demonstrated benefit for women's depressive symptoms during the early postpartum period would exert effects through 8 years., Method: The sample of 162 lower income women was racially and ethnically diverse. Women were assigned to receive an 8-week mindfulness-based intervention during pregnancy (MIND) or treatment as usual (TAU). Repeated assessments of depressive symptoms were collected using the Patient Health Questionnaire-9 at baseline, postintervention, and following childbirth (1, 2, 3-4, 5, 6, and 8 years from baseline). The most recent assessment of depressive symptoms was collected during the COVID-19 pandemic., Results: MIND and TAU women were equivalent on sociodemographic factors and depressive symptoms at baseline. Depressive symptoms at all follow-up assessments through 8 years were significantly lower among women in MIND compared to TAU. The odds of moderate or higher depressive symptoms were greater among TAU compared to MIND women at all time points except the 6-year assessment. By Year 8, 12% of women in MIND reported moderate or more severe depressive symptoms compared to 25% of women in TAU., Conclusions: Results suggest the effects of a group-based psychosocial intervention during pregnancy may endure for years, well beyond the initial perinatal period. Investing in prevention and intervention efforts for mental health during pregnancy may have sustained benefits for the well-being of women. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
- Published
- 2022
- Full Text
- View/download PDF
8. The Effects of a Prenatal Mindfulness Intervention on Infant Autonomic and Behavioral Reactivity and Regulation.
- Author
-
Noroña-Zhou AN, Coccia M, Epel E, Vieten C, Adler NE, Laraia B, Jones-Mason K, Alkon A, and Bush NR
- Subjects
- Autonomic Nervous System physiology, Child, Female, Humans, Infant, Mothers, Pregnancy, Stress, Psychological therapy, Mindfulness, Respiratory Sinus Arrhythmia physiology
- Abstract
Objective: Maternal health and wellness during pregnancy are associated with long-term health outcomes in children. The current study examined whether infants of women who participated in a mindfulness-based intervention during pregnancy that reduced levels of stress and depression, increased physical activity, and improved glucose tolerance differed on biobehavioral markers of psychopathological and physical health risk compared with infants of women who did not., Methods: Participants were 135 mother-infant dyads drawn from a racially and ethnically diverse, low-income sample experiencing high stress. The women participated in an intervention trial during pregnancy that involved assignment to either mindfulness-based intervention or treatment-as-usual (TAU). Infants of women from both groups were assessed at 6 months of age on sympathetic (preejection period), parasympathetic (respiratory sinus arrhythmia), and observed behavioral (negativity and object engagement) reactivity and regulation during the still face paradigm. Linear mixed-effects and generalized linear mixed-effects models were used to examine treatment group differences in infant outcomes., Results: Relative to those in the intervention group, infants in the TAU group showed a delay in sympathetic activation and subsequent recovery across the still face paradigm. In addition, infants in the intervention group engaged in higher proportions of self-regulatory behavior during the paradigm, compared with the TAU group. No significant effect of intervention was found for parasympathetic response or for behavioral negativity during the still face paradigm., Conclusions: Findings provide evidence that maternal participation in a short-term, group mindfulness-based intervention during pregnancy is associated with the early development of salutary profiles of biobehavioral reactivity and regulation in their infants. Because these systems are relevant for psychopathology and physical health, prenatal behavioral interventions may benefit two generations., (Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Psychosomatic Society.)
- Published
- 2022
- Full Text
- View/download PDF
9. Exploring Personal Development Workshops' Effect on Well-Being and Interconnectedness.
- Author
-
Wahbeh H, Yount G, Vieten C, Radin D, and Delorme A
- Subjects
- Adult, Emotions, Humans, Prospective Studies, Surveys and Questionnaires, Meditation, Sleep Quality
- Abstract
Introduction: Personal development workshops are increasingly popular. This study evaluated the relationships between the measures of well-being, interconnectedness, and extended perception in various workshops and explored which kinds of workshops and individual characteristics predicted changes in these outcomes. Materials and Methods: In a prospective, uncontrolled, within-participant design study, adult participants completed questionnaires and online tasks before and after personal development workshops. Three analyses were conducted: (1) examining the relationships between measures by using only pre-workshop measures using Spearman correlations; (2) exploring change scores pre- to post-workshop and workshop using Wilcoxon signed-rank test; (3) assessing workshop format and content, and individual characteristics as predictors of those change scores multivariate nonparametric regression. The following outcomes were collected: Well-being-Arizona Integrative Outcomes Scale, positive and negative affect, Dispositional Positive Emotions Scale-Compassion subscale, Sleep Quality Scale, Numeric Pain Rating Scale; Interconnectedness-Cloninger Self-Transcendence Scale, Inclusion of Nature in Self and Inclusion of the Other in Self; and Extended perception tasks-Intuition Jar, Quick Remote Viewing, Psychokinesis Bubble, and Time Estimation. The following potential predictor variables were collected: demographic, mental health, psychiatric and meditation history, Single General Self-Rated Health Question, Brief Five-Factor Inventory-10, and the Noetic Experience and Belief Scale. Workshop leaders also selected which format and content characteristics applied to their workshop. Results: Interconnectedness measures were significantly and positively correlated with well-being ( ρ : 0.27 to 0.33), positive affect ( ρ : 0.20 to 0.27), and compassion ( ρ : 0.21 to 0.32), and they were negatively correlated with sleep disturbance ( ρ : -0.13 to -0.16) and pain ( ρ : -0.11 to -0.16). Extended perception task performance was not correlated with interconnectedness or well-being. General personal development workshops improved subjective interconnectedness, well-being, positive emotion, and compassion, and they reduced sleep disturbances, negative emotion, and pain (all p' s < 0.00005). The lecture ( p = 0.03), small groups ( p = 0.001), pairs ( p = 0.01), and discussion ( p = 0.03) workshop formats were significant predictors of well-being outcomes. The workshop content categories of meditation ( p = 0.0002) and technology tools ( p = 0.01) were also predictive of well-being outcomes, with meditation being the most consistent predictor of positive well-being changes. Conscientiousness was the only significant individual characteristic predictor ( p = 0.002), although it was associated with increases in some well-being measures and decreases in others. Conclusions: This study provides preliminary evidence for the positive relationship between the subjective sense of interconnectedness and multiple well-being measures and the beneficial effects of some personal development workshops.
- Published
- 2022
- Full Text
- View/download PDF
10. Spiritual and religious competencies in psychology.
- Author
-
Vieten C and Lukoff D
- Subjects
- Cultural Diversity, Humans, Psychotherapy, Religion, Religion and Psychology, Internship and Residency, Spirituality
- Abstract
Religion and spirituality (R/S) are important aspects of human diversity that should be explicitly addressed in the field of psychology. The field has already included R/S in its definitions of multiculturalism, but while multicultural training is routinely included in doctoral level psychology course work and internship programs, it rarely includes specific training in R/S diversity. Polls of the American public indicate that religion and spirituality are important in most people's lives, and hundreds of studies demonstrate empirical links between R/S and psychological health and well-being. In clinical practice, there is evidence that clients would prefer to have their R/S addressed in psychotherapy. However, R/S issues are typically neither discussed in psychotherapy nor included in assessment or treatment planning. In research, religion and spirituality are often assessed with a single item on religious affiliation. Psychologists receive little or no training in R/S issues, in part because no agreed upon set of spiritual competencies or training guidelines exist. This article summarizes the rationale for including religious and spiritual competencies in psychology training and practice, reviews research establishing a set of religious and spiritual competencies (attitudes, knowledge, and skills) that we propose all psychologists should demonstrate, and provides practical recommendations for inquiring about religion and spirituality. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
- Published
- 2022
- Full Text
- View/download PDF
11. The Relevance of Religion and Spirituality to Mental Health: A National Survey of Current Clients' Views.
- Author
-
Oxhandler HK, Pargament KI, Pearce MJ, Vieten C, and Moffatt KM
- Subjects
- Adult, Humans, Reproducibility of Results, Social Work, Surveys and Questionnaires, Mental Health, Spirituality
- Abstract
Despite a growing interest in the relationship between religion and spirituality (RS) and mental health across helping professions, less is known about clients' perceived relevance of these areas. This article describes the development and validation of the Relevance of Religion and Spirituality to Mental Health (RRSMH) scale, and responses to the first national survey of clients' perceived relevance of RS to mental health. Specifically, a sample of 989 U.S. adults who saw a mental health care provider in the last month responded to an online survey that included 27 new items to measure clients' perceptions of the relevance of RS to mental health, both positive and negative. A confirmatory factor analysis revealed that the sample's data had an adequate fit to the final 12-item model, and the instrument's overall reliability was very good (α = .96). Descriptive analyses indicated that clients view RS as both supportive and relevant to their mental health. The RRSMH scale may be used in mental health research and practice settings. Authors recommend that RS be assessed and included in treatment planning, where appropriate, and addressed in training for mental health professionals., (© 2021 National Association of Social Workers.)
- Published
- 2021
- Full Text
- View/download PDF
12. Cardiovascular Disease-Related Pregnancy Complications Are Associated with Increased Maternal Levels and Trajectories of Cardiovascular Disease Biomarkers During and After Pregnancy.
- Author
-
Parikh NI, Laria B, Nah G, Singhal M, Vittinghoff E, Vieten C, Stotland N, Coleman-Phox K, Adler N, Albert MA, and Epel E
- Subjects
- Adult, Blood Pressure, Cardiovascular Diseases epidemiology, Cardiovascular Diseases etiology, Female, Humans, Hypertension, Pregnancy-Induced blood, Hypertension, Pregnancy-Induced epidemiology, Infant, Newborn, Interleukin-6 blood, Pre-Eclampsia blood, Pre-Eclampsia diagnosis, Pre-Eclampsia epidemiology, Pregnancy, Pregnancy Complications, Cardiovascular epidemiology, Pregnancy Outcome, Risk Factors, Tumor Necrosis Factor-alpha blood, Biomarkers blood, Blood Glucose analysis, Cholesterol blood, Hypertension, Pregnancy-Induced diagnosis, Insulin blood, Pregnancy Complications, Cardiovascular blood, Triglycerides blood
- Abstract
Background: Having a pregnancy complicated by hypertensive disorders of pregnancy (HDP) and/or having a small or preterm baby put a woman at risk for later cardiovascular disease (CVD). It is uncertain if higher maternal CVD risk factors (reflected by increased peripartum CVD biomarker levels) account for this risk, or if experiencing a complicated pregnancy itself increases a woman's CVD risk (reflected by an increase in biomarker trajectories from early pregnancy to postpartum). Methods: We conducted a secondary analysis of an 8-week mindful eating and stress reduction intervention in 110 pregnant women. We used mixed linear regression analysis to compare CVD biomarker levels and trajectories, between women with and without a CVD-related pregnancy complication (including HDP [gestational hypertension or preeclampsia] or having a small for gestational age [<10th percentile] or preterm [<37 weeks] baby), at three times: (1) 12-20 weeks of gestation, (2) 3 months postpartum, and (3) 9 months postpartum. CVD biomarkers studied included serum glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), body mass index (BMI), blood pressure (BP), interleukin-6 (IL-6), tumor necrosis factor, and lipids. We adjusted for age, maternal smoking, prepregnancy BMI, BP, age × time, and BMI × time. Results: Women had a mean age of 28 years (standard deviation [SD] 6), mean prior pregnancies of 0.8 (SD 1.0), and 22 women had one or more CVD-related pregnancy complications. HOMA-IR, diastolic BP, triglyceride, high-density lipoprotein cholesterol, and IL-6 average levels, but not trajectories, differed among women with complicated versus normal pregnancy (all p values were ≤0.04). Peripartum glucose and systolic BP trajectories were statistically greater in complicated versus normal pregnancies ( p values were 0.008 and 0.01, respectively). Conclusion: We conclude that the experience of a complicated pregnancy in addition to elevated CVD risk factor levels may both increase a woman's risk of future CVD. ClinicalTrials.gov Identifier: NCT01307683.
- Published
- 2020
- Full Text
- View/download PDF
13. The Noetic Experience and Belief Scale: A validation and reliability study.
- Author
-
Wahbeh H, Yount G, Vieten C, Radin D, and Delorme A
- Subjects
- Adult, Humans, Reproducibility of Results, Surveys and Questionnaires, Cognition, Parapsychology, Psychometrics
- Abstract
Background: Belief in the paranormal is widespread worldwide. Recent surveys suggest that subjective experiences of the paranormal are common. A concise instrument that adequately evaluates beliefs as distinct from experiences does not currently exist. To address this gap, we created the Noetic Experiences and Beliefs Scale (NEBS) which evaluates belief and experience as separate constructs. Methods: The NEBS is a 20-item survey with 10 belief and 10 experience items rated on a visual analog scale from 0-100. In an observational study, the survey was administered to 361 general population adults in the United States and a subsample of 96 one month later. Validity, reliability and internal consistency were evaluated. A confirmatory factor analysis was conducted to confirm the latent variables of belief and experience. The survey was then administered to a sample of 646 IONS Discovery Lab participants to evaluate divergent validity and confirm belief and experience as latent variables of the model in a different population. Results: The NEBS demonstrated convergent validity, reliability and internal consistency (Cronbach's alpha Belief 0.90; Experience 0.93) and test-retest reliability (Belief: r = 0.83 ; Experience: r = 0.77). A confirmatory factor analysis model with belief and experience as latent variables demonstrated a good fit. The factor model was confirmed as having a good fit and divergent validity was established in the sample of 646 IONS Discovery Lab participants. Conclusions: The NEBS is a short, valid, and reliable instrument for evaluating paranormal belief and experience., Competing Interests: No competing interests were disclosed., (Copyright: © 2020 Wahbeh H et al.)
- Published
- 2019
- Full Text
- View/download PDF
14. Measuring extraordinary experiences and beliefs: A validation and reliability study.
- Author
-
Wahbeh H, Yount G, Vieten C, Radin D, and Delorme A
- Subjects
- Adult, Factor Analysis, Statistical, Humans, Reproducibility of Results, Surveys and Questionnaires, United States, Parapsychology, Psychometrics
- Abstract
Background: Belief in the paranormal is widespread worldwide. Recent surveys suggest that subjective experiences of the paranormal are common. A concise instrument that adequately evaluates beliefs as distinct from experiences does not currently exist. To address this gap, we created the Noetic Experiences and Beliefs Scale (NEBS) which evaluates belief and experience as separate constructs. Methods: The NEBS is a 20-item survey with 10 belief and 10 experience items rated on a visual analog scale from 0-100. In an observational study, the survey was administered to 361 general population adults in the United States and a subsample of 96 one month later. Validity, reliability and internal consistency were evaluated. A confirmatory factor analysis was conducted to confirm the latent variables of belief and experience. The survey was then administered to a sample of 646 IONS Discovery Lab participants to evaluate divergent validity and confirm belief and experience as latent variables of the model in a different population. Results: The NEBS demonstrated convergent validity, reliability and internal consistency (Cronbach's alpha Belief 0.90; Experience 0.93) and test-retest reliability (Belief: r = 0.83 ; Experience: r = 0.77). A confirmatory factor analysis model with belief and experience as latent variables demonstrated a good fit. The factor model was confirmed as having a good fit and divergent validity was established in the sample of 646 IONS Discovery Lab participants. Conclusions: The NEBS is a short, valid, and reliable instrument for evaluating paranormal belief and experience., Competing Interests: No competing interests were disclosed., (Copyright: © 2020 Wahbeh H et al.)
- Published
- 2019
- Full Text
- View/download PDF
15. The Noetic Experience and Belief Scale: A validation and reliability study.
- Author
-
Wahbeh H, Yount G, Vieten C, Radin D, and Delorme A
- Subjects
- Adult, Humans, Reproducibility of Results, Surveys and Questionnaires, Cognition, Parapsychology, Psychometrics
- Abstract
Background: Belief in the paranormal is widespread worldwide. Recent surveys suggest that subjective experiences of the paranormal are common. A concise instrument that adequately evaluates beliefs as distinct from experiences does not currently exist. To address this gap, we created the Noetic Experiences and Beliefs Scale (NEBS) which evaluates belief and experience as separate constructs. Methods: The NEBS is a 20-item survey with 10 belief and 10 experience items rated on a visual analog scale from 0-100. In an observational study, the survey was administered to 361 general population adults in the United States and a subsample of 96 one month later. Validity, reliability and internal consistency were evaluated. A confirmatory factor analysis was conducted to confirm the latent variables of belief and experience. The survey was then administered to a sample of 646 IONS Discovery Lab participants to evaluate divergent validity and confirm belief and experience as latent variables of the model in a different population. Results: The NEBS demonstrated convergent validity, reliability and internal consistency (Cronbach's alpha Belief 0.90; Experience 0.93) and test-retest reliability (Belief: r = 0.83 ; Experience: r = 0.77). A confirmatory factor analysis model with belief and experience as latent variables demonstrated a good fit. The factor model was confirmed as having a good fit and divergent validity was established in the sample of 646 IONS Discovery Lab participants. Conclusions: The NEBS is a short, valid, and reliable instrument for evaluating paranormal belief and experience., Competing Interests: No competing interests were disclosed., (Copyright: © 2019 Wahbeh H et al.)
- Published
- 2019
- Full Text
- View/download PDF
16. Neighborhood Typology and Cardiometabolic Pregnancy Outcomes in the Maternal Adiposity Metabolism and Stress Study.
- Author
-
Headen I, Laraia B, Coleman-Phox K, Vieten C, Adler N, and Epel E
- Subjects
- Adolescent, Adult, Female, Humans, Middle Aged, Pregnancy, Young Adult, Pregnancy Outcome, Adiposity physiology, Obesity epidemiology, Residence Characteristics statistics & numerical data
- Abstract
Objective: This study aimed to assess associations between neighborhood typologies classified across multiple neighborhood domains and cardiometabolic pregnancy outcomes and determine variation in effectiveness of a mindfulness-based stress-reduction intervention on outcomes across neighborhood types., Methods: Neighborhoods of participants in the Maternal Adiposity Metabolism and Stress (MAMAS) intervention (n = 208) were classified across dimensions of socioeconomic, food, safety, and service/resource environments using latent class analysis. The study estimated associations between neighborhood type and three cardiometabolic pregnancy outcomes-glucose tolerance (GT) during pregnancy, excessive gestational weight gain, and 6-month postpartum weight retention (PPWR)-using marginal regression models. Interaction between neighborhood type and intervention was assessed., Results: Five neighborhood types differing across socioeconomic, food, and resource environments were identified. Compared with poor, well-resourced neighborhoods, middle-income neighborhoods with low resources had higher risk of impaired GT (relative risk [RR]: 4.1; 95% confidence Interval [CI]: 1.1, 15.5), and wealthy, well-resourced neighborhoods had higher PPWR (beta: 3.9 kg; 95% CI: 0.3, 7.5). Intervention effectiveness varied across neighborhood type with wealthy, well-resourced and poor, moderately resourced neighborhoods showing improvements in GT scores. PPWR was higher in intervention compared with control groups within wealthy, well-resourced neighborhoods., Conclusions: Consideration of multidimensional neighborhood typologies revealed important nuances in intervention effectiveness on cardiometabolic pregnancy outcomes., (© 2018 The Obesity Society.)
- Published
- 2019
- Full Text
- View/download PDF
17. Future directions in meditation research: Recommendations for expanding the field of contemplative science.
- Author
-
Vieten C, Wahbeh H, Cahn BR, MacLean K, Estrada M, Mills P, Murphy M, Shapiro S, Radin D, Josipovic Z, Presti DE, Sapiro M, Chozen Bays J, Russell P, Vago D, Travis F, Walsh R, and Delorme A
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Female, Health Surveys, Humans, Male, Middle Aged, Young Adult, Meditation methods, Research trends
- Abstract
The science of meditation has grown tremendously in the last two decades. Most studies have focused on evaluating the clinical effectiveness of mindfulness-based interventions, neural and other physiological correlates of meditation, and individual cognitive and emotional aspects of meditation. Far less research has been conducted on more challenging domains to measure, such as group and relational, transpersonal and mystical, and difficult aspects of meditation; anomalous or extraordinary phenomena related to meditation; and post-conventional stages of development associated with meditation. However, these components of meditation may be crucial to people's psychological and spiritual development, could represent important mediators and/or mechanisms by which meditation confers benefits, and could themselves be important outcomes of meditation practices. In addition, since large numbers of novices are being introduced to meditation, it is helpful to investigate experiences they may encounter that are not well understood. Over the last four years, a task force of meditation researchers and teachers met regularly to develop recommendations for expanding the current meditation research field to include these important yet often neglected topics. These meetings led to a cross-sectional online survey to investigate the prevalence of a wide range of experiences in 1120 meditators. Results show that the majority of respondents report having had many of these anomalous and extraordinary experiences. While some of the topics are potentially controversial, they can be subjected to rigorous scientific investigation. These arenas represent largely uncharted scientific terrain and provide excellent opportunities for both new and experienced researchers. We provide suggestions for future directions, with accompanying online materials to encourage such research., Competing Interests: The authors have declared that no competing interests exist.
- Published
- 2018
- Full Text
- View/download PDF
18. Exceptional experiences reported by scientists and engineers.
- Author
-
Wahbeh H, Radin D, Mossbridge J, Vieten C, and Delorme A
- Subjects
- Adult, Aged, Demography, Female, Humans, Life Change Events, Male, Mental Health, Middle Aged, Personality, Surveys and Questionnaires, Culture, Engineering, Mental Processes, Parapsychology, Science
- Abstract
Context: Throughout history people have reported exceptional experiences that appear to transcend the everyday boundaries of space and time, such as perceiving someone's thoughts from a distance. Because such experiences are associated with superstition, and some violate currently accepted materialist conventions, one might assume that scientists and engineers would be much less likely to report instances of these experiences than the general population., Objectives: To evaluate 1) the prevalence of exceptional human experiences (EHEs), 2) the level of paranormal belief, 3) the relationship between them, and 4) potential predictors of EHEs in three groups., Participants: Potential volunteers were randomly selected to receive invitations for an anonymous survey., Main Measures: Data were collected on 25 different types of EHEs, demographics, religious or spiritual affiliations, paranormal beliefs, mental health, and personality traits. Group differences were analyzed with chi-square tests and analysis of variance, and predictors were evaluated with a general linear model., Results: 94.0% of the general population (n = 283), 93.2% of scientists and engineers (n = 175), and 99.3% of enthusiasts (n = 441) endorsed at least one EHE (X
2 (2) = 21.1, p < 0.0005). Paranormal belief was highest in EHE enthusiasts, followed by scientists and the general population (F(2,769) = 116.2, p < 0.0005). Belief was positively correlated with experience (r = 0.61, p < 0.0005). An exploratory general linear model showed that variables such as mental health, personality, impact and family history predict the endorsement and frequency of EHEs. This study indicates that EHEs occur frequently in both the general population and in scientists and engineers., (Copyright © 2018. Published by Elsevier Inc.)- Published
- 2018
- Full Text
- View/download PDF
19. Effect of prenatal mindfulness training on depressive symptom severity through 18-months postpartum: A latent profile analysis.
- Author
-
Felder JN, Roubinov D, Bush NR, Coleman-Phox K, Vieten C, Laraia B, Adler NE, and Epel E
- Subjects
- Adolescent, Adult, Female, Humans, Pregnancy, Young Adult, Logistic Models, Depression physiopathology, Depression therapy, Mindfulness, Postpartum Period psychology
- Abstract
Objective: We examined whether prenatal mindfulness training was associated with lower depressive symptoms through 18-months postpartum compared to treatment as usual (TAU)., Method: A controlled, quasi-experimental trial compared prenatal mindfulness training (MMT) to TAU. We collected depressive symptom data at post-intervention, 6-, and 18-months postpartum. Latent profile analysis identified depressive symptom profiles, and multinomial logistic regression examined whether treatment condition predicted profile., Results: Three depressive symptom severity profiles emerged: none/minimal, mild, and moderate. Adjusting for relevant covariates, MMT participants were less likely than TAU participants to be in the moderate profile than the none/minimal profile (OR = 0.13, 95% CI = 0.03-0.54, p = .005)., Conclusions: Prenatal mindfulness training may have benefits for depressive symptoms during the transition to parenthood., (© 2018 Wiley Periodicals, Inc.)
- Published
- 2018
- Full Text
- View/download PDF
20. Maternal depressive symptoms and infant healthcare utilization: The moderating role of prenatal mindfulness.
- Author
-
Roubinov DS, Felder JN, Vieten C, Coleman-Phox K, Laraia B, Adler N, Wilson L, Epel E, and Bush NR
- Subjects
- Adult, Female, Humans, Infant, Pregnancy, Child of Impaired Parents statistics & numerical data, Depression therapy, Mindfulness statistics & numerical data, Patient Acceptance of Health Care statistics & numerical data, Pregnancy Complications therapy
- Published
- 2018
- Full Text
- View/download PDF
21. The mindful moms training: development of a mindfulness-based intervention to reduce stress and overeating during pregnancy.
- Author
-
Vieten C, Laraia BA, Kristeller J, Adler N, Coleman-Phox K, Bush NR, Wahbeh H, Duncan LG, and Epel E
- Subjects
- Adult, Feasibility Studies, Feeding Behavior psychology, Female, Gestational Weight Gain, Humans, Hyperphagia psychology, Overweight psychology, Pregnancy, Pregnancy Complications psychology, Stress, Psychological psychology, Treatment Outcome, Young Adult, Mindfulness methods, Overweight therapy, Pregnancy Complications therapy, Pregnant Women psychology, Stress, Psychological therapy
- Abstract
Background: Pregnancy is a time of high risk for excessive weight gain, leading to health-related consequences for mothers and offspring. Theory-based obesity interventions that target proposed mechanisms of biobehavioral change are needed, in addition to simply providing nutritional and weight gain directives. Mindfulness training is hypothesized to reduce stress and non-homeostatic eating behaviors - or eating for reasons other than hunger or caloric need. We developed a mindfulness-based intervention for high-risk, low-income overweight pregnant women over a series of iterative waves using the Obesity-Related Behavioral Intervention Trials (ORBIT) model of intervention development, and tested its effects on stress and eating behaviors., Methods: Overweight pregnant women (n = 110) in their second trimester were enrolled in an 8-week group intervention. Feasibility, acceptability, and facilitator fidelity were assessed, as well as stress, depression and eating behaviors before and after the intervention. We also examined whether pre-to-post intervention changes in outcomes of well-being and eating behaviors were associated with changes in proposed mechanisms of mindfulness, acceptance, and emotion regulation., Results: Participants attended a mean of 5.7 sessions (median = 7) out of 8 sessions total, and facilitator fidelity was very good. Of the women who completed class evaluations, at least half reported that each of the three class components (mindful breathing, mindful eating, and mindful movement) were "very useful," and that they used them on most days at least once a day or more. Women improved in reported levels of mindfulness, acceptance, and emotion regulation, and these increases were correlated with reductions in stress, depression, and overeating., Conclusions: These findings suggest that in pregnant women at high risk for excessive weight gain, it is both feasible and effective to use mindfulness strategies taught in a group format. Further, increases in certain mindfulness skills may help with better management of stress and overeating during pregnancy., Trial Registration: ClinicalTrials.gov NCT01307683 , March 8, 2011.
- Published
- 2018
- Full Text
- View/download PDF
22. THE Science OF Energy Healing.
- Author
-
Vieten C
- Subjects
- Energy Metabolism, Evidence-Based Medicine, Humans, Holistic Health, Mind-Body Relations, Metaphysical, Spiritual Therapies nursing
- Published
- 2016
23. Clinical Studies of Biofield Therapies: Summary, Methodological Challenges, and Recommendations.
- Author
-
Jain S, Hammerschlag R, Mills P, Cohen L, Krieger R, Vieten C, and Lutgendorf S
- Abstract
Biofield therapies are noninvasive therapies in which the practitioner explicitly works with a client's biofield (interacting fields of energy and information that surround living systems) to stimulate healing responses in patients. While the practice of biofield therapies has existed in Eastern and Western cultures for thousands of years, empirical research on the effectiveness of biofield therapies is still relatively nascent. In this article, we provide a summary of the state of the evidence for biofield therapies for a number of different clinical conditions. We note specific methodological issues for research in biofield therapies that need to be addressed (including practitioner-based, outcomes-based, and research design considerations), as well as provide a list of suggested next steps for biofield researchers to consider.
- Published
- 2015
- Full Text
- View/download PDF
24. Potential for a stress reduction intervention to promote healthy gestational weight gain: focus groups with low-income pregnant women.
- Author
-
Thomas M, Vieten C, Adler N, Ammondson I, Coleman-Phox K, Epel E, and Laraia B
- Subjects
- Adult, Body Mass Index, Diet, Feeding Behavior, Female, Focus Groups, Humans, Poverty, Pregnancy, Program Development, Stress, Psychological etiology, Treatment Outcome, Young Adult, Health Promotion methods, Mindfulness, Pregnant Women psychology, Stress, Psychological therapy, Weight Gain
- Abstract
Background: Prepregnancy body mass index and excessive gestational weight gain (GWG) are associated with adverse maternal and infant outcomes. Because stress contributes to obesity and eating behaviors, stress reduction interventions during pregnancy may be a novel way to influence GWG, positively affect maternal and infant outcomes, and address the obesity epidemic intergenerationally., Methods: Our research team is developing a mindfulness-based stress reduction and nutrition intervention for low-income, overweight and obese pregnant women, with healthy GWG as the primary outcome measure. To inform development of the intervention, we conducted focus groups with our target population. Focus group transcripts were analyzed for themes related to sources and importance of stress, relationship between stress and eating, and motivation for a stress reduction pregnancy intervention., Findings: Fifty-nine low-income pregnant women from the San Francisco Bay Area participated in focus groups and completed a questionnaire. The vast majority of women (80%) reported experiencing significant stress from a variety of sources and most recognized a relationship between stress and eating in their lives., Conclusions: This at-risk population seems to be extremely interested in a stress reduction intervention to support healthy GWG during pregnancy. The women in our groups described high levels of stress and a desire for programs beyond basic dietary recommendations. These findings inform practitioners and policymakers interested in pregnancy as a "window of opportunity" for behavior change that can affect the metabolic and weight trajectory both for women and their offspring., (Copyright © 2014 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF
25. Coming all the way home: integrative community care for those who serve.
- Author
-
Bobrow J, Cook E, Knowles C, and Vieten C
- Subjects
- Adult, Aged, Family, Female, Humans, Male, Middle Aged, Program Evaluation, Treatment Outcome, United States, Young Adult, Community Mental Health Services standards, Health Personnel psychology, Mental Disorders rehabilitation, Military Personnel psychology, Veterans psychology
- Abstract
This project describes the programming and evaluation of Coming Home Project (CHP) retreats that address the mental, emotional, spiritual, and relationship challenges experienced by those affected by military service and deployments. Three types of retreats held for veterans, service members and their families, as well as professional service providers, were evaluated. Original program-evaluation measures were administered to elicit feedback from participants and facilitators to optimize the intervention, and to evaluate whether the experimental and learning objectives of retreat components were achieved. Data analyses reveal statistically significant reductions in stress and isolation, as well as improvements in relaxation and hope, for all retreat participants. Implications for the success of this type of innovative, resilience-based, community programming are discussed. Future directions are suggested for further research, replicability of these services in other locations, and the incorporation of CHP retreats into existing government programs and services., (PsycINFO Database Record (c) 2013 APA, all rights reserved.)
- Published
- 2013
- Full Text
- View/download PDF
26. Recruitment and retention of pregnant women for a behavioral intervention: lessons from the maternal adiposity, metabolism, and stress (MAMAS) study.
- Author
-
Coleman-Phox K, Laraia BA, Adler N, Vieten C, Thomas M, and Epel E
- Subjects
- Adolescent, Adult, Female, Focus Groups, Humans, Interviews as Topic, Maternal Behavior, Metabolism, Middle Aged, Patient Participation statistics & numerical data, Poverty Areas, Pregnancy, Pregnant Women psychology, San Francisco, Stress, Physiological, Adiposity, Behavior Therapy methods, Patient Participation psychology, Patient Selection
- Abstract
Introduction: Recruiting participants for research studies can be challenging. Many studies fall short of their target or must prolong recruitment to reach it. We examined recruitment and retention strategies and report lessons learned in a behavioral intervention developmental trial to encourage healthy pregnancy weight gain and stress reduction in low-income overweight pregnant women., Methods: In the San Francisco Bay area from February 2010 through March 2011, we used direct and indirect strategies to recruit English-speaking overweight and obese pregnant women who were aged 18 to 45, were in the early stages of pregnancy, and who had an annual household income less than 500% of the federal poverty guidelines. Eligible women who consented participated in focus groups or an 8-week behavioral intervention. We identified successful recruiting strategies and sites and calculated the percentage of women who were enrolled and retained., Results: Of 127 women screened for focus group participation, 69 were eligible and enrolled. A total of 57 women participated in 9 focus groups and 3 women completed individual interviews for a completion rate of 87%. During recruitment for the intervention, we made contact with 204 women; 135 were screened, 33% were eligible, and 69.1% of eligible women enrolled. At 1 month postpartum, 82.6% of eligible women completed an assessment. Recruiting at hospital-based prenatal clinics was the highest-yielding strategy., Conclusion: The narrow window of eligibility for enrolling early stage pregnant women in a group intervention presents obstacles. In-person recruitment was the most successful strategy; establishing close relationships with providers, clinic staff, social service providers, and study participants was essential to successful recruitment and retention.
- Published
- 2013
- Full Text
- View/download PDF
27. Genome-wide linkage scan of antisocial behavior, depression, and impulsive substance use in the UCSF family alcoholism study.
- Author
-
Gizer IR, Ehlers CL, Vieten C, Feiler HS, Gilder DA, and Wilhelmsen KC
- Subjects
- Alcoholism complications, Antisocial Personality Disorder complications, Chromosomes, Human genetics, Depression complications, Family, Female, Humans, Impulsive Behavior complications, Impulsive Behavior genetics, Lod Score, MMPI, Male, Middle Aged, Multivariate Analysis, San Francisco, Substance-Related Disorders complications, Universities, Alcoholism genetics, Antisocial Personality Disorder genetics, Depression genetics, Genetic Linkage, Genetic Predisposition to Disease, Genome-Wide Association Study, Substance-Related Disorders genetics
- Abstract
Objective: Epidemiological and clinical studies suggest that the rates of antisocial behavior, depression, and impulsive substance use are increased among individuals diagnosed with alcohol dependence relative to those who are not. Thus, the present study conducted genome-wide linkage scans of antisocial behavior, depression, and impulsive substance use in the University of California at San Francisco Family Alcoholism Study., Methods: Antisocial behavior, depressive symptoms, and impulsive substance use were assessed using three scales from the Minnesota Multiphasic Personality Inventory - 2nd ed.: the Antisocial Practices content scale, the Depression content scale, and the revised MacAndrew Alcoholism scale. Linkage analyses were carried out using a variance components approach., Results: Suggestive evidence of linkage to three genomic regions independent of alcohol and cannabis dependence diagnostic status was observed: the Antisocial Practices content scale showed evidence of linkage to chromosome 13 at 11 cM, the MacAndrew Alcoholism scale showed evidence of linkage to chromosome 15 at 47 cM, and all three scales showed evidence of linkage to chromosome 17 at 57-58 cM., Conclusion: Each of these regions has shown previous evidence of linkage and association to substance dependence as well as other psychiatric disorders such as mood and anxiety disorders, attention-deficit hyperactivity disorder, and schizophrenia, thus suggesting potentially broad relations between these regions and psychopathology.
- Published
- 2012
- Full Text
- View/download PDF
28. Distant healing of surgical wounds: an exploratory study.
- Author
-
Schlitz M, Hopf HW, Eskenazi L, Vieten C, and Radin D
- Subjects
- Adult, Affect, Attitude of Health Personnel, Breast Neoplasms psychology, Breast Neoplasms surgery, Collagen metabolism, Confounding Factors, Epidemiologic, Culture, Elective Surgical Procedures psychology, Female, Health Status, Humans, Middle Aged, Postoperative Complications therapy, Research Design, Self Report, Surgery, Plastic psychology, Treatment Outcome, Wounds and Injuries therapy, Complementary Therapies, Intention, Mental Health, Perception, Postoperative Complications psychology, Trust, Wound Healing
- Abstract
Background: Distant healing intention (DHI) is one of the most common complementary and alternative medicine (CAM) healing modalities, but clinical trials to date have provided ambivalent support for its efficacy. One possible reason is that DHI effects may involve variables that are sensitive to unknown, uncontrolled, or uncontrollable factors., Objective: To examine 2 of those potential variables-expectation and belief-we explored the effects of DHI on objective and psychosocial measures associated with surgical wounds in 72 women undergoing plastic surgery., Design: Participants were randomly assigned to 1 of 3 groups: blinded and receiving DHI (DH), blinded and not receiving DHI (control), and knowing that they were receiving DHI (expectancy). Outcome measures included collagen deposition in a surrogate wound and several self-report measures. DHI was provided by experienced distant healers. No differences in the main measures were observed across the three groups., Results: Participants' previous belief in the efficacy of DHI was negatively correlated with the status of their mental health at the end of the study (P = .04, 2-tailed), and healers' perceptions of the quality of their subjective "contact" with the participants were negatively correlated both with change in mood (P = .001) and with collagen deposition (P = .04). A post-hoc analysis found that among participants assigned to receive DHI under blinded conditions, those undergoing reconstructive surgery after breast cancer treatment reported significantly better change in mood than those who were undergoing purely elective cosmetic surgery (P = .004)., Conclusion: If future DHI experiments confirm the post-hoc observations, then some of the ambiguity observed in earlier DHI studies may be attributable to interactions among participants' and healers' beliefs, their expectations, and their motivations., (Copyright © 2012 Elsevier Inc. All rights reserved.)
- Published
- 2012
- Full Text
- View/download PDF
29. Electrocortical activity prior to unpredictable stimuli in meditators and nonmeditators.
- Author
-
Radin DI, Vieten C, Michel L, and Delorme A
- Subjects
- Aged, Case-Control Studies, Electroencephalography methods, Female, Humans, Light, Male, Middle Aged, Sound, Acoustic Stimulation, Brain Waves physiology, Meditation, Photic Stimulation, Relaxation physiology
- Abstract
Advanced meditators occasionally report experiences of timelessness, or states of awareness that seem to transcend the usual boundaries of the subjective present. This type of experience was investigated in eight experienced meditators and eight matched controls by measuring 32 channels of EEG before, during, and after exposure to unpredictable light and sound stimuli. The experiment postulated that if some aspect of consciousness extends beyond the present moment, then prestimulus electrocortical signals should differ depending on stimuli that were about to be selected by a truly random process, and that if such experiences were catalyzed through meditation practice, then prestimulus differences should be more apparent in meditators than in nonmeditators. Each of the 32 EEG channels was baseline adjusted on each trial by the electrical potential averaged between two- and one-second prestimulus, then for each channel the average potential was determined from one-second prestimulus to stimulus onset. The resulting means across subjects in each group were compared by stimulus type using randomized permutation procedures and corrected for multiple comparisons. Within the control group, no EEG channels showed significant prestimulus differences between light versus sound stimulus conditions, but within the meditator group five of 32 channels resulted in significant differences (P < .05, two tailed). Comparisons between control and meditator groups showed significant prestimulus differences prior to audio tone stimuli in 14 of 32 channels (P < .05, two tailed, of which eight channels were P < .005, two tailed). This outcome successfully replicates effects reported in earlier experiments, suggesting that sometimes the subjective sense of awareness extending into the future may be ontologically accurate., (Copyright © 2011 Elsevier Inc. All rights reserved.)
- Published
- 2011
- Full Text
- View/download PDF
30. Linkage scan of alcohol dependence in the UCSF Family Alcoholism Study.
- Author
-
Gizer IR, Ehlers CL, Vieten C, Seaton-Smith KL, Feiler HS, Lee JV, Segall SK, Gilder DA, and Wilhelmsen KC
- Subjects
- Alcoholism diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Genetic Predisposition to Disease, Genetic Testing methods, Genome-Wide Association Study, Genotype, Humans, Alcoholism genetics, Genetic Linkage
- Abstract
Ample data suggest that alcohol dependence represents a heritable condition, and several research groups have performed linkage analysis to identify genomic regions influencing this disorder. In the present study, a genome-wide linkage scan for alcohol dependence was conducted in a community sample of 565 probands and 1080 first-degree relatives recruited through the UCSF Family Alcoholism Study. The Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) was used to derive DSM-IV alcohol dependence diagnoses. Although no loci achieved genome-wide significance (i.e., LOD score > 3.0), several linkage peaks of interest (i.e., LOD score > 1.0) were identified. When the strict DSM-IV alcohol dependence diagnosis requiring the temporal clustering of symptoms served as the phenotype, linkage peaks were identified on chromosomes 1p36.31-p36.22, 2q37.3, 8q24.3, and 18p11.21-p11.2. When the temporal clustering of symptoms was not required, linkage peaks were again identified on chromosomes 1p36.31-p36.22 and 8q24.3 as well as novel loci on chromosomes 1p22.3, 2p24.3-p24.1, 9p24.1-p23, and 22q12.3-q13.1. Follow-up analyses were conducted by performing linkage analysis for the 12 alcohol dependence symptoms assessed by the SSAGA across the support intervals for the observed linkage peaks. These analyses demonstrated that different collections of symptoms often assessing distinct aspects of alcohol dependence (e.g., uncontrollable drinking and withdrawal vs. tolerance and drinking despite health problems) contributed to each linkage peak and often yielded LOD scores exceeding that reported for the alcohol dependence diagnosis. Such findings provide insight into how specific genomic regions may influence distinct aspects of alcohol dependence., (Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.)
- Published
- 2011
- Full Text
- View/download PDF
31. Linkage analyses of cannabis dependence, craving, and withdrawal in the San Francisco family study.
- Author
-
Ehlers CL, Gizer IR, Vieten C, and Wilhelmsen KC
- Subjects
- Alcoholism genetics, Chromosome Mapping, Computer Simulation, Family, Female, Genotype, Humans, Male, Middle Aged, Phenotype, San Francisco, Genetic Linkage, Marijuana Abuse genetics, Substance Withdrawal Syndrome genetics
- Abstract
Cannabis is the most widely used illicit drug in the United States. There is ample evidence that cannabis use has a heritable component, yet the genes underlying cannabis use disorders are yet to be completely identified. This study's aims were to map susceptibility loci for cannabis use and dependence and two narrower cannabis-related phenotypes of "craving" and "withdrawal" using a family study design. Participants were 2,524 adults participating in the University of California San Francisco (UCSF) Family Alcoholism Study. DSM-IV diagnoses of cannabis dependence, as well as indices of cannabis craving and withdrawal, were obtained using a modified version of the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA). Genotypes were determined for a panel of 791 microsatellite polymorphisms. Multipoint variance component LOD scores were obtained using SOLAR. Genome-wide significance for linkage (LOD > 3.0) was not found for the DSM-IV cannabis dependence diagnosis; however, linkage analyses of cannabis "craving" and the cannabis withdrawal symptom of "nervous, tense, restless, or irritable" revealed five sites with LOD scores over 3.0 on chromosomes 1, 3, 6, 7, and 9. These results identify new regions of the genome associated with cannabis use phenotypes as well as corroborate the importance of several chromosome regions highlighted in previous linkage analyses for other substance dependence phenotypes.
- Published
- 2010
- Full Text
- View/download PDF
32. Development of an acceptance-based coping intervention for alcohol dependence relapse prevention.
- Author
-
Vieten C, Astin JA, Buscemi R, and Galloway GP
- Subjects
- Adult, Affect, Behavior, Addictive prevention & control, Emotions, Humans, Male, Middle Aged, Pilot Projects, Secondary Prevention, Stress, Psychological therapy, Adaptation, Psychological, Alcoholism prevention & control, Cognitive Behavioral Therapy methods, Meditation methods
- Abstract
Both psychological and neurobiological findings lend support to the long-standing clinical observation that negative affect is involved in the development and maintenance of alcohol dependence, and difficulty coping with negative affect is a common precipitant of relapse after treatment. Although many current approaches to relapse prevention emphasize change-based strategies for managing negative cognitions and affect, acceptance-based strategies for preventing relapse to alcohol use are intended to provide methods for coping with distress that are fundamentally different from, though in theory complementary to, approaches that emphasize control and change. This paper describes the development of Acceptance-Based Coping for Relapse Prevention (ABCRP), a new intervention for alcohol-dependent individuals who are within 6 months of having quit drinking. Results of preliminary testing indicate that the intervention is feasible with this population; and a small uncontrolled pilot study (N = 23) showed significant (P < .01) improvements in self-reported negative affect, emotional reactivity, perceived stress, positive affect, psychological well-being, and mindfulness level, as well as a trend (P = .06) toward reduction in craving severity between pre- and postintervention assessments. The authors conclude that this acceptance-based intervention seems feasible and holds promise for improving affect and reducing relapse in alcohol-dependent individuals, warranting further research.
- Published
- 2010
- Full Text
- View/download PDF
33. Age at regular drinking, clinical course, and heritability of alcohol dependence in the San Francisco family study: a gender analysis.
- Author
-
Ehlers CL, Gizer IR, Vieten C, Gilder A, Gilder DA, Stouffer GM, Lau P, and Wilhelmsen KC
- Subjects
- Age Factors, Age of Onset, Alcohol Drinking psychology, Alcoholism genetics, Alcoholism psychology, Female, Humans, Male, Middle Aged, San Francisco, Alcohol Drinking epidemiology, Alcoholism epidemiology, Disease Progression, Genetic Predisposition to Disease psychology, Sex Characteristics
- Abstract
We examined gender differences in age of onset, clinical course, and heritability of alcohol dependence in 2,524 adults participating in the University of California San Francisco (UCSF) family study of alcoholism. Men were significantly more likely than women to have initiated regular drinking during adolescence. Onset of regular drinking was not found to be heritable but was found to be significantly associated with a shorter time to onset of alcohol dependence. A high degree of similarity in the sequence of alcohol-related life events was found between men and women, however, men experienced alcohol dependence symptoms at a younger age and women had a more rapid clinical course. Women were found to have a higher heritability estimate for alcohol dependence (h(2)= .46) than men (h(2)= .32). These findings suggest that environmental factors influencing the initiation of regular drinking rather than genetic factors associated with dependence may in part underlie some of the gender differences seen in the prevalence of alcohol dependence in this population. (Am J Addict 2010;00:1-10).
- Published
- 2010
- Full Text
- View/download PDF
34. Cannabis dependence in the San Francisco Family Study: age of onset of use, DSM-IV symptoms, withdrawal, and heritability.
- Author
-
Ehlers CL, Gizer IR, Vieten C, Gilder DA, Stouffer GM, Lau P, and Wilhelmsen KC
- Subjects
- Adolescent, Adult, Age of Onset, Diagnostic and Statistical Manual of Mental Disorders, Family, Female, Humans, Male, Middle Aged, San Francisco epidemiology, Sex Factors, Young Adult, Marijuana Abuse epidemiology, Substance Withdrawal Syndrome epidemiology
- Abstract
Cannabis is the most widely used illicit drug in the United States, yet the role of genetics in individual symptoms associated with cannabis use disorders has not been evaluated. The purpose of the present set of analyses was to describe the symptomatology and estimate the heritability of DSM-IV criteria/symptoms of cannabis dependence in a large sample of families. Participants were 2524 adults, participating in the University of California San Francisco (UCSF) Family Study of alcoholism. Seventy percent of the sample had ever used cannabis and 13.9% met DSM-IV criteria for cannabis dependence. Younger age at first cannabis use was found to be significantly associated with a shortened survival to becoming cannabis dependent. Although a greater percentage of men met criteria for cannabis dependence, women were found to demonstrate "telescoping" as indexed by a shorter survival time from initial use to dependence as compared to men. A cannabis withdrawal syndrome was identified in users, the primary symptoms of which were nervousness, appetite change, and sleep disturbance. Cannabis use (h(2)=0.31) and dependence (h(2)=0.20), age at first use, individual DSM-IV criteria for dependence, and cannabis-use associated symptoms of depression, trouble concentrating and paranoia were all found to be heritable. These findings suggest that within this population that cannabis use and dependence, as well as individual cannabis dependence symptoms have a significant heritable component, that cannabis dependence is more likely to occur when use begins during adolescence, and that the cannabis dependence syndrome includes a number of heritable untoward psychiatric side effects including withdrawal.
- Published
- 2010
- Full Text
- View/download PDF
35. Heritability of MMPI-2 scales in the UCSF family alcoholism study.
- Author
-
Gizer IR, Seaton-Smith KL, Ehlers CL, Vieten C, and Wilhelmsen KC
- Subjects
- Adolescent, Adult, Aged, Alcoholism epidemiology, Alcoholism psychology, Analysis of Variance, Antisocial Personality Disorder diagnosis, Antisocial Personality Disorder genetics, Behavior, Addictive diagnosis, Behavior, Addictive genetics, Depression diagnosis, Depression genetics, Female, Humans, Male, Middle Aged, Phenotype, San Francisco epidemiology, Young Adult, Alcoholism diagnosis, Alcoholism genetics, Family, MMPI statistics & numerical data
- Abstract
The current study evaluated the heritability of personality traits and psychopathology symptoms assessed by the Minnesota Multiphasic Personality Inventory 2nd Edition (MMPI-2) in a family-based sample selected for alcohol dependence. Participants included 950 probands and 1,204 first-degree relatives recruited for the University of California at San Francisco (UCSF) Family Alcoholism Study. Heritability estimates for MMPI-2 scales ranged from .25 to .49. When alcohol dependence was used as a covariate, heritability estimates remained significant but generally declined. However, when the MMPI-2 scales were used as covariates to estimate the heritability of alcohol dependence, the scales measuring antisocial behavior, depressive symptoms, and addictive behavior led to moderate increases in the heritability of alcohol dependence. This suggests that the scales may explain some of the non-genetic variance in the alcohol dependence diagnosis in this population when used as covariates, and thus may serve to produce a more homogeneous and heritable alcohol-dependence phenotype.
- Published
- 2010
- Full Text
- View/download PDF
36. Negative affect, emotional acceptance, and smoking cessation.
- Author
-
Carmody TP, Vieten C, and Astin JA
- Subjects
- Humans, Emotions, Mood Disorders, Smoking Cessation
- Abstract
This article describes recent theoretical developments and empirical findings regarding the role of negative affect (NA) and emotion regulation in nicotine dependence and smoking cessation. It begins with a review of affect-based models of addiction that address conditioning, affect motivational, and neurobiological mechanisms and then describes the role of NA and emotion regulation in the initiation and maintenance of cigarette smoking. Next, the role of emotion regulation, coping skill deficits, depression, and anxiety sensitivity in explaining the relationship between NA and smoking relapse are discussed. We then review recent models of affect regulation, including emotional intelligence, reappraisal and suppression, and emotional acceptance, and describe implications for substance abuse and smoking cessation interventions. Finally, we point out the need for further investigations of the moderating role of individual differences in response to NA in the maintenance of nicotine dependence, and controlled randomized trials testing the efficacy of acceptance-based interventions in facilitating smoking cessation and relapse prevention.
- Published
- 2007
- Full Text
- View/download PDF
37. The University of California, San Francisco Family Alcoholism Study. I. Design, methods, and demographics.
- Author
-
Vieten C, Seaton KL, Feiler HS, and Wilhelmsen KC
- Subjects
- Adult, Aged, Family, Female, Humans, Male, Middle Aged, Research Design, San Francisco, Siblings, Alcoholism epidemiology, Alcoholism genetics, Genetic Linkage genetics, Universities statistics & numerical data
- Abstract
Background: The University of California, San Francisco (UCSF) Family Alcoholism Study is a project designed to identify genetic loci that influence susceptibility to alcohol dependence and related phenotypes. Evidence supports a substantial genetic contribution to alcoholism susceptibility. However, the genetic epidemiology of alcoholism is complex, and its clinical manifestation is heterogeneous, making phenotype definition and demonstration of linkage difficult. Despite these challenges, some progress has been made toward identifying genes., Methods: The UCSF Family Alcoholism Study used a small family design, focusing primarily on sibling pairs and parent-child trios for linkage and association studies. Alcoholism-related phenotypes were assessed through interview and self-report questionnaires, with a focus on unidimensional and subphenotypical traits. Data-driven approaches to determining the most promising phenotypes for genetic analysis are being used. Both genome-wide scan and candidate gene approaches were used., Results: The study enrolled 2154 individuals from 970 families from December 1995 through January 2003. Test-retest and interrater reliability for clinical data are very good, and power estimates suggest that this study will have adequate power by linkage analysis to detect loci with moderate effects. Design, methods, and sample demographics of the UCSF Family Study are presented, along with intrafamilial correlations for primary diagnostic phenotypes., Conclusions: Plans for genetic analysis, novel approaches to phenotype refinement, and the implications of ascertainment bias for heritability estimates are discussed.
- Published
- 2004
- Full Text
- View/download PDF
38. Effective strategies for recruiting families ascertained through alcoholic probands.
- Author
-
Seaton KL, Cornell JL, Wilhelmsen KC, and Vieten C
- Subjects
- Alcoholism epidemiology, Humans, Alcoholism genetics, Patient Selection, Pedigree, Research Design statistics & numerical data
- Abstract
Background: Recruiting a large number of participants meeting strict inclusion criteria can be challenging, particularly when selecting for a condition associated with a social stigma such as alcoholism, when participation involves collection of medical specimens and sensitive information, and when the participation of family members or other collaterals is required. Developing and implementing a successful recruitment plan depends upon identifying the most effective recruitment strategies given the available resources., Methods: Several strategies for recruiting subjects for a large family study on the genetics of alcoholism were evaluated over a two-year period with regard to participant yield, time and cost expenditure., Results: Overall effectiveness of a recruitment strategy was determined based on a composite of yield, cost and time expenditure. The most effective recruitment strategies were direct mail, press release, the Internet and treatment center collaborations., Conclusion: Results provide insight into successful strategies for recruiting large numbers of participants and their family members selected for a condition associated with a social stigma.
- Published
- 2004
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.