1. [Kinsbourne syndrome: review of our cases].
- Author
-
Rodríguez-Barrionuevo AC, Caballero-Morales MA, Delgado-Marqués MP, Mora-Ramírez MD, and Martínez-Antón J
- Subjects
- Abdominal Neoplasms complications, Abdominal Neoplasms epidemiology, Adolescent, Adrenocorticotropic Hormone therapeutic use, Brain Damage, Chronic etiology, Cerebellar Ataxia drug therapy, Cerebellar Ataxia etiology, Child, Child, Preschool, Electroencephalography, Female, Follow-Up Studies, Ganglioneuroblastoma complications, Ganglioneuroblastoma epidemiology, Humans, Male, Myoclonus drug therapy, Myoclonus etiology, Ocular Motility Disorders drug therapy, Ocular Motility Disorders etiology, Recurrence, Retrospective Studies, Syndrome, Virus Diseases complications, Cerebellar Ataxia epidemiology, Myoclonus epidemiology, Ocular Motility Disorders epidemiology
- Abstract
Introduction: The childhood opsoclonus-myoclonus or Kinsbourne syndrome, is a uncommon process, of acute or subacute beginning, which affects infant and children. It's course is characterized by opsoclonus, polimyoclonias and cerebellar ataxia. The disease is frequently associated to neuroblastoma (46%)., Material and Methods: We present a retrospective study on 9 patients, emphasizing the clinical presentation and the evolution aspects., Results and Conclusions: We found changes in the EEG in three cases. Most surprising is the scarce incidence of neuroblastoma, which has been found only in a one out of nine patients. We found three cases with relapse during the treatment or on withdrawal and one of them relapsed twice again. The evolution has been variable, since 5/9 patient have presented some type of mild or moderate neuro-psychological sequelae. Out of three patient with relapses, two presented permanent neurological sequelae. A patient which suffered three relapses, is also the one which presents more serious sequelae.
- Published
- 1998