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[Kinsbourne syndrome: review of our cases].
- Source :
-
Revista de neurologia [Rev Neurol] 1998 Jun; Vol. 26 (154), pp. 956-9. - Publication Year :
- 1998
-
Abstract
- Introduction: The childhood opsoclonus-myoclonus or Kinsbourne syndrome, is a uncommon process, of acute or subacute beginning, which affects infant and children. It's course is characterized by opsoclonus, polimyoclonias and cerebellar ataxia. The disease is frequently associated to neuroblastoma (46%).<br />Material and Methods: We present a retrospective study on 9 patients, emphasizing the clinical presentation and the evolution aspects.<br />Results and Conclusions: We found changes in the EEG in three cases. Most surprising is the scarce incidence of neuroblastoma, which has been found only in a one out of nine patients. We found three cases with relapse during the treatment or on withdrawal and one of them relapsed twice again. The evolution has been variable, since 5/9 patient have presented some type of mild or moderate neuro-psychological sequelae. Out of three patient with relapses, two presented permanent neurological sequelae. A patient which suffered three relapses, is also the one which presents more serious sequelae.
- Subjects :
- Abdominal Neoplasms complications
Abdominal Neoplasms epidemiology
Adolescent
Adrenocorticotropic Hormone therapeutic use
Brain Damage, Chronic etiology
Cerebellar Ataxia drug therapy
Cerebellar Ataxia etiology
Child
Child, Preschool
Electroencephalography
Female
Follow-Up Studies
Ganglioneuroblastoma complications
Ganglioneuroblastoma epidemiology
Humans
Male
Myoclonus drug therapy
Myoclonus etiology
Ocular Motility Disorders drug therapy
Ocular Motility Disorders etiology
Recurrence
Retrospective Studies
Syndrome
Virus Diseases complications
Cerebellar Ataxia epidemiology
Myoclonus epidemiology
Ocular Motility Disorders epidemiology
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0210-0010
- Volume :
- 26
- Issue :
- 154
- Database :
- MEDLINE
- Journal :
- Revista de neurologia
- Publication Type :
- Academic Journal
- Accession number :
- 9658467