1. Sulfemodin 8-O-beta-D-glucoside, a new sulfated anthraquinone glycoside, and antioxidant phenolic compounds from Rheum emodi.
- Author
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Krenn L, Presser A, Pradhan R, Bahr B, Paper DH, Mayer KK, and Kopp B
- Subjects
- Anthraquinones chemistry, Anthraquinones pharmacology, Antioxidants chemistry, Antioxidants pharmacology, Benzofurans chemistry, Benzofurans isolation & purification, Benzofurans pharmacology, Biphenyl Compounds, Glycosides chemistry, Glycosides pharmacology, Inhibitory Concentration 50, Molecular Structure, Nepal, Nuclear Magnetic Resonance, Biomolecular, Picrates pharmacology, Plant Roots chemistry, Anthraquinones isolation & purification, Antioxidants isolation & purification, Glycosides isolation & purification, Plants, Medicinal chemistry, Rheum chemistry
- Abstract
A sulfated emodin glucoside, emodin 8-O-beta-D-glucopyranosyl-6-O-sulfate (1), was isolated from the roots of Rheum emodi in an investigation of the active constituents of this Nepalese medicinal plant, and its structure was determined by spectroscopic and chemical methods. Additionally, two rare auronols, carpusin (2) and maesopsin (3), besides other anthraquinones and phenolics, were isolated and identified. Compounds 2 and 3 showed significant antioxidant activity in the DPPH assay, while chrysophanol, physcion, and emodin and their 8-O-glucosides were found to be inactive.
- Published
- 2003
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