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Sulfemodin 8-O-beta-D-glucoside, a new sulfated anthraquinone glycoside, and antioxidant phenolic compounds from Rheum emodi.
- Source :
-
Journal of natural products [J Nat Prod] 2003 Aug; Vol. 66 (8), pp. 1107-9. - Publication Year :
- 2003
-
Abstract
- A sulfated emodin glucoside, emodin 8-O-beta-D-glucopyranosyl-6-O-sulfate (1), was isolated from the roots of Rheum emodi in an investigation of the active constituents of this Nepalese medicinal plant, and its structure was determined by spectroscopic and chemical methods. Additionally, two rare auronols, carpusin (2) and maesopsin (3), besides other anthraquinones and phenolics, were isolated and identified. Compounds 2 and 3 showed significant antioxidant activity in the DPPH assay, while chrysophanol, physcion, and emodin and their 8-O-glucosides were found to be inactive.
- Subjects :
- Anthraquinones chemistry
Anthraquinones pharmacology
Antioxidants chemistry
Antioxidants pharmacology
Benzofurans chemistry
Benzofurans isolation & purification
Benzofurans pharmacology
Biphenyl Compounds
Glycosides chemistry
Glycosides pharmacology
Inhibitory Concentration 50
Molecular Structure
Nepal
Nuclear Magnetic Resonance, Biomolecular
Picrates pharmacology
Plant Roots chemistry
Anthraquinones isolation & purification
Antioxidants isolation & purification
Glycosides isolation & purification
Plants, Medicinal chemistry
Rheum chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 0163-3864
- Volume :
- 66
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Journal of natural products
- Publication Type :
- Academic Journal
- Accession number :
- 12932135
- Full Text :
- https://doi.org/10.1021/np0301442