1. Multi-organ sarcoidosis treatment with fumaric acid esters: a case report and review of the literature.
- Author
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Zouboulis CC, Lippert U, and Karagiannidis I
- Subjects
- Administration, Oral, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Follow-Up Studies, Humans, Middle Aged, Radiography, Thoracic methods, Rare Diseases, Sarcoidosis, Pulmonary diagnostic imaging, Sarcoidosis, Pulmonary drug therapy, Severity of Illness Index, Skin Diseases diagnosis, Treatment Outcome, Fumarates therapeutic use, Sarcoidosis diagnosis, Sarcoidosis drug therapy, Skin Diseases drug therapy
- Abstract
Sarcoidosis is a rare, systemic disease that is characterized by the formation of granulomas in various organs, including the skin. As the etiology remains unknown, the treatment of sarcoidosis is challenging. We present a 47-year-old female patient with progressive, multi-organ sarcoidosis who had a complete clinical improvement of the skin lesions, a moderate reduction in pulmonary opacities on chest X-ray, a marked subjective improvement in general status and pulmonary efficiency and a marked reduction in serum angiotensin-converting enzyme and soluble interleukin-2 receptor after 6 months of therapy with fumaric acid esters. The present case and similar reports in the literature highlight the probable efficacy of fumaric acid esters in the treatment of sarcoidosis and other non-infectious, granulomatous diseases., (© 2014 S. Karger AG, Basel.)
- Published
- 2014
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