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Multi-organ sarcoidosis treatment with fumaric acid esters: a case report and review of the literature.
- Source :
-
Dermatology (Basel, Switzerland) [Dermatology] 2014; Vol. 228 (3), pp. 202-6. Date of Electronic Publication: 2014 Mar 27. - Publication Year :
- 2014
-
Abstract
- Sarcoidosis is a rare, systemic disease that is characterized by the formation of granulomas in various organs, including the skin. As the etiology remains unknown, the treatment of sarcoidosis is challenging. We present a 47-year-old female patient with progressive, multi-organ sarcoidosis who had a complete clinical improvement of the skin lesions, a moderate reduction in pulmonary opacities on chest X-ray, a marked subjective improvement in general status and pulmonary efficiency and a marked reduction in serum angiotensin-converting enzyme and soluble interleukin-2 receptor after 6 months of therapy with fumaric acid esters. The present case and similar reports in the literature highlight the probable efficacy of fumaric acid esters in the treatment of sarcoidosis and other non-infectious, granulomatous diseases.<br /> (© 2014 S. Karger AG, Basel.)
- Subjects :
- Administration, Oral
Dose-Response Relationship, Drug
Drug Administration Schedule
Female
Follow-Up Studies
Humans
Middle Aged
Radiography, Thoracic methods
Rare Diseases
Sarcoidosis, Pulmonary diagnostic imaging
Sarcoidosis, Pulmonary drug therapy
Severity of Illness Index
Skin Diseases diagnosis
Treatment Outcome
Fumarates therapeutic use
Sarcoidosis diagnosis
Sarcoidosis drug therapy
Skin Diseases drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1421-9832
- Volume :
- 228
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Dermatology (Basel, Switzerland)
- Publication Type :
- Academic Journal
- Accession number :
- 24686198
- Full Text :
- https://doi.org/10.1159/000358428