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West Nile virus (WNV) has become a significant cause of arboviral infection of the central nervous system (CNS) in the United States since it was first identified in 1999. (1) [...], Reports of clinical manifestations of West Nile virus (WNV) infections in children have been relatively rare. Four cases of WNV infection in children are described: the first report of prolonged encephalitis and fulminant hepatitis caused by WNV, and 3 other presentations of WNV, including the first report of ocular involvement in a child. Pediatrics 2004;114:1673-1675; West Nile virus, hepatitis, vitritis, encephalitis, meningitis, child. ABBREVIATIONS. WNV, West Nile virus; CNS, central nervous system; CBC, complete blood count; WBC, white blood cell; CSF, cerebrospinal fluid; CPK, creatine phosphokinase; HSV, herpes simplex virus; CT, computed tomography; Ig, immunoglobulin; ELISA, enzyme-linked immunosorbent assay.

To the Editor.-- I write to add several comments about the recent report in Pediatrics on 4 cases of West Nile virus (WNV) infection in children? With regard to the [...]