Spectrum of clinical manifestations of West Nile virus infection in children

Reports of clinical manifestations of West Nile virus (WNV) infections in children have been relatively rare. Four cases of WNV infection in children are described: the first report of prolonged encephalitis and fulminant hepatitis caused by WNV, and 3 other presentations of WNV, including the first report of ocular involvement in a child. Pediatrics 2004;114:1673-1675; West Nile virus, hepatitis, vitritis, encephalitis, meningitis, child. ABBREVIATIONS. WNV, West Nile virus; CNS, central nervous system; CBC, complete blood count; WBC, white blood cell; CSF, cerebrospinal fluid; CPK, creatine phosphokinase; HSV, herpes simplex virus; CT, computed tomography; Ig, immunoglobulin; ELISA, enzyme-linked immunosorbent assay.
West Nile virus (WNV) has become a significant cause of arboviral infection of the central nervous system (CNS) in the United States since it was first identified in 1999. (1) [...]