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1. Sequential acyl halide-aldehyde cyclocondensation and enzymatic resolution as a route to enantiomerically enriched beta-lactones

Author

Nelson, Scott G. and Spencer, Keith L.

Subjects
Chemistry, Organic -- Research, Halides -- Physiological aspects, Aldehydes -- Physiological aspects, Enzymes -- Physiological aspects, Lactones -- Physiological aspects, Biological sciences, Chemistry
Abstract

Research has been conducted on the beta-lactones. The preparation of the optically active beta-lactones via enzymatic resolution of the racemic 4-substituted-2-oxetanones derived from the acyl halide-aldehyde reactions has been investigated.

Published
2000

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