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1. Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload

Author

Koitabashi, Norimichi, Danner, Thomas, Zaiman, Ari L., Pinto, Yigal M., Rowell, Janelle, Mankowski, Joseph, Zhang, Dou, Nakamura, Taishi, Takimoto, Eiki, and Kass, David A.

Subjects
Transforming growth factors, Bone morphogenetic proteins, Health care industry
Abstract

The cardiac pathological response to sustained pressure overload involves myocyte hypertrophy and dysfunction along with interstitial changes such as fibrosis and reduced capillary density. These changes are orchestrated by mechanical [...]

Published
2011
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