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Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload
- Source :
- Journal of Clinical Investigation. June 1, 2011, Vol. 121 Issue 6, p2301, 12 p.
- Publication Year :
- 2011
-
Abstract
- The cardiac pathological response to sustained pressure overload involves myocyte hypertrophy and dysfunction along with interstitial changes such as fibrosis and reduced capillary density. These changes are orchestrated by mechanical [...]
- Subjects :
- Transforming growth factors
Bone morphogenetic proteins
Health care industry
Subjects
Details
- Language :
- English
- ISSN :
- 00219738
- Volume :
- 121
- Issue :
- 6
- Database :
- Gale General OneFile
- Journal :
- Journal of Clinical Investigation
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.348997208
- Full Text :
- https://doi.org/10.1172/JCI44824