Search

Simonds Park in Burlington, Massachusetts, is the community's flagship park as it features a variety of amenities and is centrally located for community access. Throughout the years, improvements and additions [...]

Randstad director of travel transformation Yvonne Moya, ITM board member and outgoing Willis Towers Watson global travel director Emma Jones and Takeda global head of travel Michelle De Costa spoke [...]

At Humanists International, supporting individuals at risk is an important part of our strategic plan, whether it's through our campaigning for the repeal of blasphemy laws, our advocacy at the [...]

Mention the word 'sustainability' to a small business and it will conjure up a couple of reactions. The word 'sustainable' has, of course, become common parlance for businesses that are [...]

My company solves problems for small businesses based on data sets and evidence that guides businesses from different localities and sectors to support that is proven to work for their [...]

Customers are buying and UK businesses are using every channel at their disposal to service demand while being in the spaces and places of the target shopper. Because founders come [...]

When the first lockdown was mandated in the UK, I read of people on furlough who took time to learn new languages and pursue long-forgotten skills. Not so for millions [...]

Understanding supply chain resilience and robustness is increasingly important for supply chain managers. This is due to the growing complexity of contemporary supply chains and the subsequent increased probability of experiencing a disruption. Few studies within the risk management literature have empirically disentangled the concepts of resilience and robustness or explored their antecedents. This study utilizes a contingent resource-based view perspective to understand the relationship between specific resources (information sharing and connectivity), capabilities (visibility), and performance in terms of supply chain resilience and robustness. In addition, it utilizes supply base complexity as a moderating factor. Survey data collected from 264 UK manufacturing plants suggest that supply chain connectivity and information sharing resources lead to a supply chain visibility capability which enhances resilience and robustness. Of the four dimensions of complexity, only scale is found to have a strong moderating effect on this relationship, while geographic dispersion, differentiation, and delivery complexity do not have contingent effects. This study highlights theoretical and managerial implications for approaches to resilience and robustness. Keywords: risk management; supply chain resilience; supply chain robustness; resource-based view; supply management; buyer/supplier relationships; survey methods; regression analysis; factor analysis, INTRODUCTION Supply chain risk management remains a key managerial challenge that affects the performance of organizations (Altay & Ramirez, 2010; Hendricks & Singhal, 2005b). Despite increased attention from academia and [...]

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2009.09.016 Byline: Hisashi Sahara, Akira Shimizu, Kentaro Setoyama, Masayoshi Okumi, Manei Oku, Emma Samelson-Jones, Kazuhiko Yamada Abbreviations: CO, carbon monoxide; COHb, carboxyhemoglobin; CXR, chest x-ray; HMGB1, high-mobility group box 1; IRI, ischemia-reperfusion injury; Pao.sub.2, arterial oxygen tension Abstract: Carbon monoxide is produced endogenously as a by-product of heme catalysis and has been shown to reduce ischemia-reperfusion injury in a variety of organs in murine models. The aims of this translational research were to establish an in situ porcine lung model of warm ischemia-reperfusion injury and to evaluate the cytoprotective effects of low-dose inhaled carbon monoxide in this model. Author Affiliation: Xenotransplantation Surgery Section, Frontier Science Research Center, Kagoshima University, Kagoshima, Japan Article History: Received 2 June 2009; Revised 15 August 2009; Accepted 7 September 2009 Article Note: (footnote) This research was supported by a Grant-in-Aid for Young Scientists (to H.S.) and the Kagoshima University Research Awards (to K.Y.)., Disclosures: None.

Background: Interest in the development of dairy products naturally enriched in conjugated linoleic acid (CLA) exists. However, feeding regimens that enhance the CLA content of milk also increase concentrations of trans- 18:1 fatty acids. The implications for human health are not yet known. Objective: This study investigated the effects of consuming dairy products naturally enriched in cis-9,trans-11 CLA (and trans-11 18:1) on the blood lipid profile, the atherogenicity of LDL, and markers of inflammation and insulin resistance in healthy middle-aged men. Design: Healthy middle-aged men (n = 32) consumed ultra-heat-treated milk, butter, and cheese that provided 0.151 g/d (control) or 1.421 g/d (modified) cis-9,trans-11 CLA for 6 wk. This was followed by a 7-wk washout and a crossover to the other treatment. Results: Consumption of dairy products enriched with cis-9, trans-11 CLA and trans-11 18:1 did not significantly affect body weight, inflammatory markers, insulin, glucose, triacylglycerols, or total, LDL, and HDL cholesterol but resulted in a small increase in the ratio of LDL to HDL cholesterol. The modified dairy products changed LDL fatty acid composition but had no significant effect on LDL particle size or the susceptibility of LDL to oxidation. Overall, increased consumption of full-fat dairy products and naturally derived trans fatty acids did not cause significant changes in cardiovascular disease risk variables, as may be expected on the basis of current health recommendations. Conclusion: Dairy products naturally enriched with cis-9,trans-11 CLA and trans- 11 18:1 do not appear to have a significant effect on the blood lipid profile. KEY WORDS Cholesterol, conjugated linoleic acid, high-density lipoprotein, low-density lipoprotein, triacylglycerol

Background: Conjugated linoleic acid (CLA) is reported to have weight-reducing and antiatherogenic properties when fed to laboratory animals. However, the effects of CLA on human health and, in particular, the effects of individual CLA isomers are unclear. Objective: This study investigated the effects of 3 doses of highly enriched cis-9,trans-11 (0.59, 1.19, and 2.38 g/d) or trans-10,cis-12 (0.63, 1.26, and 2.52 g/d) CLA preparations on body composition, blood lipid profile, and markers of insulin resistance in healthy men. Design: Healthy men consumed 1, 2, and 4 capsules sequentially, containing either 80% cis-9,trans-11 CLA or 80% trans-10,cis-12 CLA for consecutive 8-wk periods. This phase was followed by a 6-wk washout and a crossover to the other isomer. Results: Body composition was not significantly affected by either isomer of CLA. Mean plasma triacylglycerol concentration was higher during supplementation with trans-10,cis- 12 CLA than during that with cis-9,trans- 11 CLA, although there was no influence of dose. There were significant effects of both isomer and dose on plasma total cholesterol and LDL-cholesterol concentrations but not on HDL-cholesterol concentration. The ratios of LDL to HDL cholesterol and of total to HDL cholesterol were higher during supplementation with trans-10,cis-12 CLA than during that with cis9,trans-11 CLA. CLA supplementation had no significant effect on plasma insulin concentration, homeostasis model for insulin resistance, or revised quantitative insulin sensitivity check index. Conclusion: Divergent effects of cis-9,trans-11 CLA and trans10,cis-12 CLA appear on the blood lipid profile in healthy humans: trans-10,cis-12 CLA increases LDL:HDL cholesterol and total:HDL cholesterol, whereas cis-9,trans-11 CLA decreases them. Am J Clin Nutr 2004;80:614-20. KEY WORDS Cholesterol, conjugated linoleic acid, high-density lipoprotein, low-density lipoprotein, triacylglycerol

One of the major issues faced particularly by the nurses working in acute care is a lack of access to good food. Numerous studies have indicated a link between shift working and obesity and related diseases such as coronary heart disease.

Nurse-patient relationships are getting affected due to the increasing pressure on the NHS to accommodate more patients in less time, thus hampering patient care. Such increased efficiency, paper work and bureaucracy leave the nurses with very less time to provide proper care and attention to the patient.