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1. An alternative synthesis of clindamycin

Author

GRAHAM P. STEVENS and KEITH BOWDEN

Subjects
clindamycin, N-chlorosuccinmide, Chemistry, QD1-999
Abstract

A novel synthesis of clindamycin from lincomycin using N-chlorosuccinimide and triphenylphosphine is reported. This results in high yields and avoids the use of tetrachloromethane employed in the current manufacturing process.

Published
2000

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