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An alternative synthesis of clindamycin

Authors :
GRAHAM P. STEVENS
KEITH BOWDEN
Source :
Journal of the Serbian Chemical Society, Vol 65, Iss 10, Pp 691-694 (2000)
Publication Year :
2000
Publisher :
Serbian Chemical Society, 2000.

Abstract

A novel synthesis of clindamycin from lincomycin using N-chlorosuccinimide and triphenylphosphine is reported. This results in high yields and avoids the use of tetrachloromethane employed in the current manufacturing process.

Details

Language :
English
ISSN :
03525139
Volume :
65
Issue :
10
Database :
Directory of Open Access Journals
Journal :
Journal of the Serbian Chemical Society
Publication Type :
Academic Journal
Accession number :
edsdoj.fa5e31b0a967471ebf047dbfe489decd
Document Type :
article