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1. Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes

Author

Rupert L. Mayer, Rein Verbeke, Caroline Asselman, Ilke Aernout, Adillah Gul, Denzel Eggermont, Katie Boucher, Fabien Thery, Teresa M. Maia, Hans Demol, Ralf Gabriels, Lennart Martens, Christophe Bécavin, Stefaan C. De Smedt, Bart Vandekerckhove, Ine Lentacker, and Francis Impens

Subjects
Science
Abstract

Currently, no approved vaccines for Listeria monocytogenes are available. Here, the authors use immunopeptidomics to map bacterial peptides presented on infected cells and identify antigens that, as mRNA vaccine, provide protection in mice.

Published
2022
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