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A simple, low-cost technique has been developed for the rapid fabrication of single-layered paper-based microfluidic devices (μPADs). This technique, for the first time, made use of the deposition of patterned adhesive tape into the filter paper to construct hydrophobic barriers, with the help of toluene. Unlike other reported multi-layered μPADs that merely made use of adhesive tape as a separate layer for sealing or fluid flow controlling, the patterned adhesive tape was simultaneously dissolved and penetrated into the filter paper, which resulted in the successful transfer of the pattern from the tape to the filter paper. To demonstrate the effectiveness of this approach, nitrite and glucose were individually measured; detection limits as low as 0.015 ± 0.004 mM and 0.022 ± 0.006 mM were reported for nitrite and glucose, respectively. Multiplexed analysis of both analytes was also carried out with respective detection limits of 0.048 ± 0.005 mM and 0.025 ± 0.006 mM for nitrite and glucose. The application of the method was demonstrated by measuring nitrite and glucose in spiked artificial urine samples and satisfied recovery results were obtained.

This article addresses the conservation treatment of a 19th century framed miniatured portrait painted on ivory. The object was in poor condition, with all the pieces necessary to hold the object separated and with the attempt of securing these parts with brown and clear adhesive tape. This article addresses the condition of the object and consequently, the treatments undertaken for its conservation: tape removal procedure with heat and solvents; paper mending and repairs; cleaning process of the back of the painting and remounting process of the frame with appropriate conservation materials to strengthen it and provide stability.