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1,1,2-Trifluoroethene (HFO-1123) is anticipated for use as a refrigerant with low global warming potential. Inhalation studies on HFO-1123 in rats indicated a low potential for toxicity (NOAELs ≥ 20,000 ppm). In contrast, single inhalation exposure of Goettingen® minipigs (≥ 500 ppm) and New Zealand white rabbits (≥ 1250 ppm) resulted in severe toxicity. It has been suggested that these pronounced species-differences in toxicity may be attributable to species-differences in biotransformation of HFO-1123 via the mercapturic acid pathway. Therefore, the overall objective of this study was to evaluate species-differences in glutathione (GSH) dependent in vitro metabolism of HFO-1123 in susceptible versus less susceptible species and humans as a basis for human risk assessment. Biotransformation of HFO-1123 to S-(1,1,2-trifluoroethyl)-L-glutathione (1123-GSH) and subsequent cysteine S-conjugate β-lyase-mediated cleavage of the corresponding cysteine conjugate (1123-CYS) was monitored in hepatic and renal subcellular fractions of mice, rats, minipigs, rabbits, and humans. While 1123-GSH formation occurred at higher rates in rat and rabbit liver S9 compared to minipig and human S9, increased β-lyase cleavage of 1123-CYS was observed in minipig kidney cytosol as compared to cytosolic fractions of other species. Increased β-lyase activity in minipig cytosol was accompanied by time-dependent formation of monofluoroacetic acid (MFA), a highly toxic compound that interferes with cellular energy production via inhibition of aconitase. Consistent with the significantly lower β-lyase activity in human cytosols, the intensity of the MFA signal in human cytosols was only a fraction of the signal obtained in minipig subcellular fractions. Even though the inconsistencies between GSH and β-lyase-dependent metabolism do not allow to draw a firm conclusion on the overall contribution of the mercapturic acid pathway to HFO-1123 biotransformation and toxicity in vivo, the β-lyase data suggest that humans may be less susceptible to HFO-1123 toxicity compared to minipigs. [ABSTRACT FROM AUTHOR]

We demonstrated a nearly impedance-matched high-overtone bulk acoustic resonator (HBAR) operating at super high frequency ranges using an epitaxial AlN piezoelectric layer directly grown on a conductive SiC cavity substrate with no metal layer insertion. The small impedance mismatch was verified from the variation in the free spectral range (FSR); the experimentally obtained FSR spectra were greatly reproduced using the Mason model. Broadband phonon cavity modes up to the K-band (26.5 GHz) were achieved at an AlN layer thickness of 200 nm. The high figure of merit of f × Q = 1.3 × 10 13 Hz at 10 GHz was also obtained. Our nearly impedance-matched high-quality HBAR will enable the development of microwave signal processing devices for 5G and future 6G communication systems, such as low-phase noise oscillators and acoustic filters, as well as research on high-frequency acoustic systems hybridized with electric, optical, and magnetic systems. [ABSTRACT FROM AUTHOR]

Chiral molecules can exhibit spin-selective charge emission, which is known as chirality-induced spin selectivity1,2. Despite the constituent light elements of the molecules, their spin polarization can approach or even exceed that of typical ferromagnets. This powerful capability may lead to applications in the chiral spintronics2 field. Although the origin of spin selectivity is elusive, two microscopic phenomena have been suggested based on experimental results: effective enhancement of spin–orbit interactions3 and chirality represented by a pair of oppositely polarized spins4,5. However, the hypotheses remain to be verified. Here we report the simultaneous observation of these two phenomena in an organic chiral superconductor by magnetoresistance measurements in the vicinity of the superconducting transition temperature. A pair of oppositely polarized spins is demonstrated by spatially mapping the spin polarity in an electric alternating current excitation. The obtained spin polarization exceeds that of the Edelstein effect6–10 by several orders of magnitude, which indicates an effective enhancement of the spin–orbit interaction. Our results demonstrate a solid-state analogue of spin accumulations assumed for chiral molecules, and may provide clues to the origin of their molecular counterparts. In addition, the innovative capability of spin-current sourcing will invigorate superconducting spintronics research11.The simultaneous observation of spin–orbit interaction enhancement and chirality represented by a pair of oppositely polarized spins is reported for an organic chiral superconductor in the vicinity of the superconducting transition temperature. [ABSTRACT FROM AUTHOR]

In this work, the problem of radiation scattering by ice crystals typical for cirrus clouds is solved for a 94-GHz radar (wavelength 3189 µm) and a lidar (wavelength 0.355 µm); the ice refractive indices are 1.7864 + 0.0032i and 1.3249 + 0i, respectively. The scattering matrices are calculated within the physical optics approximation and the discrete dipole approximation for the case of randomly oriented particles with sizes from 4 to 1000 µm. The ratio of the radar and lidar backscattering signals in the backward direction (the so-called radar–lidar ratio) is calculated for a wide range of the particle size for typical shapes of cirrus cloud ice crystals. It is shown that this ratio can be used for estimating the size of ice crystals in cirrus clouds. [ABSTRACT FROM AUTHOR]

To clarify the limiting factor of carrier transport in organic molecular semiconductors, we performed charge modulation spectroscopy of a field-effect transistor with a 3,11-didecyldinaphtho[2,3-d:2′,3′-d′]benzo[1,2-b:4,5-b′]dithiophene (C10-DNBDT-NW) single crystal, which showed a hole-carrier mobility of 8.4 cm2 V−1 s−1 at 295 K. The terahertz absorption of electric-field-induced hole carriers increases with decreasing frequency down to 150 cm−1 (4.5 THz). However, it is not reproduced by the simple Drude model but tends to be suppressed with decreasing frequency. The spectral shape of the absorption and the mobility value were simultaneously reproduced by the Drude–Anderson model, which incorporates carrier scattering due to thermal molecular fluctuations. The frequency of the intermolecular vibration that dominates carrier scattering is estimated to be approximately 8 cm−1, which is in good agreement with the theoretically predicted value. Moreover, analyses of the absorption spectra at low temperatures reveal that the mobility increases to 14 cm2 V−1 s−1 at 240 K. These results demonstrate that thermal molecular fluctuations limit the mobility. [ABSTRACT FROM AUTHOR]

This document is a correction notice for an article titled "Species-differences in the in vitro biotransformation of trifluoroethene (HFO-1123)" published in the Archives of Toxicology. The correction addresses an error in the presentation of Figure 5 in the original article. The corrected figure shows the identification of species-differences in the formation of certain metabolites in minipigs, rabbits, and humans. The correction is provided by multiple authors. Springer Nature, the publisher, remains neutral in terms of jurisdictional claims and institutional affiliations. [Extracted from the article]

We study horizontal ice plates in clouds using satellite lidar measurements of the Cloud‐Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO). This study investigates global microphysical and geographical properties of horizontal ice plates to obtain insights into ice‐plate climatology based on lidar's long‐term measurements during 2006–2014. We then summarize the effects of the lidar's viewing angle change from 0.3° to 3.0° in 2007 on satellite particle phase/shape classifications. Using a classification algorithm developed in the previous studies, we show that the ice plate detection decreases by 81.7% due the tilting. With an updated version of this algorithm, 30.8% of these are recovered, although 50.8% remain undetected. Nevertheless, this study also shows that geographical characteristics of ice plates are still preserved during the off‐nadir period (within the remaining 50%), suggesting the undiscovered climatological information on ice plates in the post‐2007 observations. According to our analysis, the tilting mainly affects horizontal ice plate detection, while the impacts on water and randomly oriented ice detections are limited. The temperature of the ice plates ranges from −25.5°C and −7.5°C, with a mode temperature of −13.5°C, although the ice plates also occur ubiquitously across mid‐ to high‐latitudes between −20°C and −40°C, which is much colder than what found in previous nadir studies. This study offers a detailed discussion on the fundamental characteristics of horizontal ice plates that will provide robust information for the algorithm preparation for future satellite lidar observations such as the Earth, Clouds, Aerosol and Radiation Explorer (EarthCARE). Key Points: Global characteristics of horizontal ice plates in clouds were investigated using long‐term Cloud‐Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) satellite observations.Effects of the lidar viewing angle change, from 0.3° to 3.0°, on satellite ice‐plate detection algorithms were evaluated.Horizontal ice plates were found ubiquitously over the globe, generally in a stable condition with little annual variability. [ABSTRACT FROM AUTHOR]

Ultrafast electronic-phase change in solids by light, called photoinduced phase transition, is a central issue in the field of non-equilibrium quantum physics, which has been developed very recently. In most of those phenomena, charge or spin orders in an original phase are melted by photocarrier generations, while an ordered state is usually difficult to be created from a non-ordered state by a photoexcitation. Here, we demonstrate that a strong terahertz electric-field pulse changes a Mott insulator of an organic molecular compound in κ-(ET)2Cu[N(CN)2]Cl (ET = bis(ethylenedithio)tetrathiafulvalene), to a macroscopically polarized charge-order state; herein, electronic ferroelectricity is induced by the collective intermolecular charge transfers in each dimer. In contrast, in an isostructural compound, κ-(ET)2Cu2(CN)3, which shows the spin-liquid state at low temperatures, a similar polar charge order is not stabilized by the same terahertz pulse. From the comparative studies of terahertz-field-induced second-harmonic-generation and reflectivity changes in the two compounds, we suggest the possibility that a coupling of charge and spin degrees of freedom would play important roles in the stabilization of polar charge order. Photoinduced phase transition is a central issue in the field of non-equilibrium quantum physics. Here, the authors demonstrate that a terahertz electric-field pulse changes a Mott insulator of an organic molecular compound to a macroscopically polarized charge-order state. [ABSTRACT FROM AUTHOR]

We report a high performance mid-infrared pump visible probe measurement system, which can measure phase-sensitive responses to a mid-infrared pulse along the oscillating electromagnetic field. In this system, the pump light is a phase-locked mid-infrared pulse with a temporal width of 100 fs, which is produced via difference frequency generation (DFG) from two idler pulses of two optical parametric amplifiers (OPAs) that are excited by the same Ti:sapphire regenerative amplifier. The probe pulse is a visible pulse with a temporal width of 9 fs and is generated from a custom-built non-collinear OPA. By measuring the electric-field waveforms of mid-infrared pump pulses with electro-optic sampling and evaluating their carrier envelope phase (CEP) and the temporal positions of their envelopes relative to ultrashort visible probe pulses, we are able to perform double feedback corrections that eliminate both the following sources of drift. The CEP drift in mid-infrared pulses originating from fluctuations in the difference of optical-path lengths of the two idler pulses before the DFG is corrected by inserting a wedge plate in one idler path, and the drift in pump–probe delay times due to fluctuations in the difference of the overall optical-path lengths of the pump and probe pulses is corrected with mechanical delay lines. In this double feedback system, the absolute carrier phase of mid-infrared pulses can be fixed within 200 mrad and errors in the measurement of phase-sensitive responses can be reduced to within 1 fs over a few tens of hours. [ABSTRACT FROM AUTHOR]

Antimalarials are usually recommended for the first-line systemic treatment of cutaneous lupus erythematosus. Alopecia in patients with discoid lupus erythematosus (DLE) is sometimes a refractory condition in spite of topical therapies. We herein described a case of DLE on the scalp with a pathological change of a xanthomatous reaction, which was successfully treated with hydroxychloroquine (HCQ). A 34-year-old woman presented with hair loss to the parietal region. She had been diagnosed with systemic lupus erythematosus (SLE) four years previously. Treatment with 30 mg/day of prednisolone (PSL) had been initiated, and the dose was gradually reduced. At 10 mg/day of PSL, she had noticed her hair loss. Physical examination revealed some small erythematous lesions to the parietal region with accompanying hair loss. Pathological findings of the erythematous lesion on her head revealed thickening of the basement membrane zone, the interface dermatitis with vacuolar degeneration, and both superficial perivascular and perifollicular infiltration of inflammatory cells in the dermis. In addition, there was an infiltrate of xanthomatous cells detected in the papillary dermis, which were positive for CD68 and CD163. The patient started treatment with HCQ at a dose of 200 mg/day. The skin lesions completely resolved within five months after initiation of HCQ without increase in the dose of PSL. Xanthomatous reactions are rarely recognized in lupus erythematosus. The chronic epithelial injury in DLE could be implicated in triggering the secondary reactive process of a xanthomatous reaction. We believe that the reaction seen in our patient was a secondary change to pathological alteration due to SLE. However, as yet unrecognized factors may play a role in the development of a xanthomatous reaction in DLE. [ABSTRACT FROM AUTHOR]

Crystallographic studies on microcrystalline silicon (μc-Si) films, which were prepared by very-high-frequency plasma-enhanced chemical vapor deposition at a low temperature of 180 °C, have been performed employing thickness evolutions of x-ray and electron diffraction measurements. The experimental results revealed that amorphous phase in μc-Si is transited to crystalline phase in solid phase in whole region from the top to the bottom, and the transition to the (220) orientation is dominantly found. These growth phenomena are interpreted in terms of a proposed model, i.e., the hybrid-phase growth model consisting of conventional vapor-phase growth at the surface plus the solid-phase crystallization occurring in the film. Moreover, the hybrid-phase growth, particularly solid-phase crystallization at low temperatures, is discussed in conjunction with the further results on the thickness evolutions associated with μc-Si films deposited on various underlayers or at substrate temperatures of 160–350 °C, or at SiH4 concentrations of 3%–5%. [ABSTRACT FROM AUTHOR]

A detailed investigation of photocarrier transport and localized states in undoped hydrogenated microcrystalline silicon (μc-Si:H) has been performed using the modulated photocurrent (MPC) technique. The MPC-derived drift mobility shows a systematic variation with crystalline grain size and volume fraction, as well as a distinct anisotropy. The physical implications of these observations are discussed in accordance with models that consider connectivity of crystalline grains and geometry of individual grains. The frequency spectra of MPC mobility and their dependence on excitation intensity are also analyzed in comparison with those observed for hydrogenated amorphous silicon (a-Si:H), leading to a common property of localized states that can explain the experimental results for these materials. © 2003 American Institute of Physics. [ABSTRACT FROM AUTHOR]

Examines the general relationship between complex impedance and linear stability in electrochemical systems. Representation of complex impedance as the ratio of characteristic polynomials of the Jacobian matrices of linearized system under potentiostatic and galvanostic control.

In microcrystal samples of the prototypical organic molecular semiconductors rubrene and C10-DNTT (2,9-didecyl-dinaphtho[2,3-b:2′,3′-f]thieno[3,2-b]thiophene), we measured spectra of complex optical conductivity caused by photocarriers with optical-pump terahertz-probe spectroscopy. We analyzed the σ ̃ ω spectra using the Drude-Smith model and evaluated the DC mobility μ DC , which includes extrinsic effects, and the intrinsic mobility μ int . The resulting μ DC and μ int values are comparable to the mobility values obtained using transport measurements of polycrystalline and single-crystalline field-effect transistors, respectively. This correspondence demonstrates that the intrinsic mobility values of organic molecular semiconductors can be evaluated from the measurements of microcrystal samples using transient terahertz spectroscopy. [ABSTRACT FROM AUTHOR]

Summary: Background: Myositis‐specific autoantibodies (MSAs) are associated with unique clinical subsets in polymyositis/dermatomyositis (PM/DM). Autoantibodies against transcriptional intermediary factor (TIF)‐1γ and TIF‐1α are known to be MSAs. Previously, we reported that TIF‐1β is also targeted in patients with DM with or without concomitant anti‐TIF‐1α/γ antibodies. Objectives: To evaluate the clinical features of seven cases with anti‐TIF‐1β antibodies alone. Methods: Serum autoantibody profiles were determined, and protein and RNA immunoprecipitation studies were conducted. Western blotting was performed to confirm autoantibody reactivity against TIF‐1β. Results: Anti‐TIF‐1β antibody was identified by immunoprecipitation assay in 24 cases. Among them, seven patients were positive for anti‐TIF‐1β antibody alone. Six of the seven patients were classified as having DM. Among the six cases of DM, two patients had no muscle weakness and normal creatine kinase (CK) levels, and were classified as having clinically amyopathic DM. Four patients had muscle weakness, but three of them had normal serum CK levels that responded well to systemic steroids. Characteristic features of DM included skin rashes, such as Gottron sign, periungual erythema, punctate haemorrhage on the perionychium and facial erythema including heliotrope, which were observed in 86%, 57%, 86% and 71% of our cases, respectively. One of the seven patients had appendiceal cancer. None of the patients had interstitial lung disease. Conclusions: Seven patients were confirmed to have anti‐TIF‐1β antibody without any other MSAs, including TIF‐1α/γ antibodies, and six of them were diagnosed with DM. We suggest that anti‐TIF‐1β antibody is an MSA, and that it is associated with clinically amyopathic DM or DM with mild myopathy. What's already known about this topic? Previously we reported that transcriptional intermediary factor (TIF)‐1β is also targeted in patients with dermatomyositis with or without concomitant anti‐TIF‐1α/γ antibodies.Anti‐TIF‐1β antibody could be a myositis‐specific autoantibody. What does this study add? We describe seven patients with anti‐TIF‐1β antibody but without anti‐TIF‐1α/γ reactivity.Anti‐TIF‐1β antibody is possibly associated with clinically amyopathic dermatomyositis or dermatomyositis with mild myopathy. Linked Comment:Fiorentino. Br J Dermatol 2019; 180:709–710. Respond to this article Plain language summary available online [ABSTRACT FROM AUTHOR]

The plasma sensor on the sixth H‐II Transfer Vehicle (HTV) measured the depletion of electron density during some maneuver operations for attitude or altitude control. In this paper, we first discuss the on‐orbit observation of electron density depletion during the entire lifetime of the HTV. On‐orbit data showed that both altitude and attitude control maneuvers caused the depletion effect. The geocentric coordinates and universal time were also shown to confirm the depletion effect around the HTV by using other techniques, such as total electron content based on the Global Navigation Satellite System network. In the latter part of the paper, we discuss the cause of the depletion effect based on past literature. To analyze the interaction between thruster plume gas and ionospheric plasma, computational fluid dynamics simulations were conducted to analyze the number density distribution of molecules around the HTV. It was found that the combination of charge exchange and dissociative recombination possibly caused the depletion of electron density during altitude control maneuvers, due to neutral particles being ejected from the thrusters and a time delay in the reaction response. During attitude control maneuvers, the electrons of ionospheric plasma were pushed away from the plasma sensor by dense neutral clouds. Plain Language Summary: The electron current sensor on the H‐II Transfer Vehicle that transports supplies to the International Space Station observed the depletion of electron density during maneuver operations in orbit. The present study showed the measured data and discussed the causes of electron density depletion. This discussion was supported by computational fluid dynamics and simple numerical analyses. The present study found that the distance between the thruster and monitor, and the time to chemical reaction are important parameters to clarify the cause of electron density depletion. Key Points: The plasma sensor on the HTV observes electron density depletion during maneuver operations in the ionosphereComputational Fluid Dynamics simulations were conducted to clarify the number density distribution of neutral particles emitted from thrustersDissociative recombination and the push away effect are possible causes of electron density depletion [ABSTRACT FROM AUTHOR]

Background Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a commonly occurring condition related to systemic autoimmune disease. It is characterized histopathologically by a distinct pattern of granulomatous inflammation in the presence or absence of leukocytoclastic vasculitis. The properties of granulomatous cells in PNGD are still uncertain. Objective We sought further investigation on the phenotype of the infiltrated cells in PNGD from two patients with systemic lupus erythematosus (SLE) and reviewed the previous published reports in order to provide a comprehensive summary on the clinical features of PNGD in SLE. Methods The immunohistochemical features of granulomatous cells in PNGD associated with SLE were analyzed. Immunohistochemical studies were performed on sections from our two cases using antibodies against CD68, CD163, CD15, Factor XIIIa, myeloperoxidase and neutrophil elastase. The clinical characteristics of the SLE patients who developed PNGD were also evaluated. We included all cases retrieved through a PubMed search with the key words PNGD and SLE. Results Cutaneous lesions consisted of erythematous plaques distributed on the face and upper limbs in both cases. The infiltrated cells were mainly positive for CD68 and CD163, a phenotype suggestive of M2 macrophages. Some mature neutrophils and lymphocytes were also present. A review of the literature of PNGD associated with SLE revealed a predominance in females, high prevalence of lupus nephritis and a good response to systemic steroids, with frequent skin lesions relapses during tapering of the treatment. Limitations This study examined only two cases; the pathogenesis of the disease remains to be clarified. Conclusion PNGD lesions were abundantly infiltrated by M2 macrophages, suggesting that they may have a role in this condition. SLE accompanied by PNGD might be associated with lupus nephritis and frequent relapses of skin lesions. [ABSTRACT FROM AUTHOR]

Presents information on a study which investigated the localized deep states in undoped α-silicon:hydrogen using current transient spectroscopy. Outline of current transient spectroscopy; Experimental details; Results and discussion; Conclusions.

Focuses on a study which applied a spectroscopy technique based on modulated photoconductivity measurements with varying illumination level to investigate the capture coefficients and the energy distribution of defect states in undoped amorphous silicon. Theory of modulated photoconductivity spectroscopy; Discussion of the carrier capture process and the defect formation mechanism; Evolution of modulated photoconductivity response with illumination level.

Proposes a method for investigating the diffusion of photocarriers in semiconductors by the analysis of phase shift between a temporally modulated illumination grating and its inducing photocurrent. Theory of the modulated photocarrier grating technique; Diffusion length measurement in amorphous silicon; Comparison with the result of the steady-state photocarrier grating measurement.

Presents a study which observed photocurrent mutiplication in a hydrogenated amorphous silicon-based p-i, amorphous silicon-nitrogen alloy and i-n structure junction under a reverse biased condition. Schematic illustration of the p-type amorphous silicon carbide, undoped hydrogenated amorphous silicon and n-type microcrystalline silicon heterojunction; Experimental results for photocurrent characteristics; Model of photocurrent multiplication.

Describes a high-efficiency solar cell having the structure of a microcrystalline silicon carbide on polycrystalline silicon. Details of experimental techniques used; Electron cyclotron resonance plasma chemical vapor system and deposition conditions of microcrystalline silicon carbide; Description of electrical and optical properties of dopes microcrystalline silicon carbide films.

Small papular pseudolymphoma (SPP)[1] is characterized by multiple angiomatous papules, mainly on the acral sites of the hands and feet in children. Histological examination demonstrated a dense, bandlike or nodular infiltrate of mononuclear cells immediately below the epidermis and a small nodular infiltrate of mononuclear cells around eccrine gland structures (Fig. a). [Extracted from the article]

We report the ultrafast switching of the magnetic state in the course of photoinduced phase transition from an insulator with short-range charge and orbital order (CO/OO) to a ferromagnetic metal in perovskite-type Gd0.55Sr0.45MnO3. The femtosecond Kerr rotation and reflectivity measurements, which detect the spin and charge dynamics, respectively, have revealed that the metallic state is formed within the time resolution (∼200 fs); however, magnetization increases with the time constant of 0.5 ps. The relatively slow increase of the magnetization is attributable to the magnetic-field-induced alignment of ferromagnetic domains in the initially produced metallic state. [ABSTRACT FROM AUTHOR]

Migration of wild and cultivated juvenile honmoroko Gnathopogon caerulescens of from the spawning and nursery areas in Lake Biwa were investigated, both in the Ibanaiko Lagoon and its outlet to Daido River, using beam‐trawl surveys in 2013 and 2014. The study demonstrated migration of G. caerulescens from a nursery lagoon toward Lake Biwa after the juvenile stage. These findings appear to be the first direct evidence for migration of an exclusively pelagic cyprinid species from a littoral nursery to a pelagic adult habitat in a large deep lake. [ABSTRACT FROM AUTHOR]

We developed a method for classifying hydrometeor particle types, including cloud and precipitation phase and ice crystal habit, by a synergistic use of CloudSat/Cloud Profiling Radar (CPR) and Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO)/Cloud-Aerosol LIdar with Orthogonal Polarization (CALIOP). We investigated how the cloud phase and ice crystal habit characterized by CALIOP globally relate with radar reflectivity and temperature. The global relationship thus identified was employed to develop an algorithm for hydrometeor type classification with CPR alone. The CPR-based type classification was then combined with CALIPSO-based type characterization to give CPR-CALIOP synergy classification. A unique aspect of this algorithm is to exploit and combine the lidar's sensitivity to thin ice clouds and the radar's ability to penetrate light precipitation to offer more complete picture of vertically resolved hydrometeor type classification than has been provided by previous studies. Given the complementary nature of radar and lidar detections of hydrometeors, our algorithm delivers 13 hydrometeor types: warm water, supercooled water, randomly oriented ice crystal (3D-ice), horizontally oriented plate (2D-plate), 3D-ice + 2D-plate, liquid drizzle, mixed-phase drizzle, rain, snow, mixed-phase cloud, water + liquid drizzle, water + rain, and unknown. The global statistics of three-dimensional occurrence frequency of each hydrometeor type revealed that 3D-ice contributes the most to the total cloud occurrence frequency (53.8%), followed by supercooled water (14.3%), 2D-plate (9.2%), rain (5.9%), warm water (5.7%), snow (4.8%), mixed-phase drizzle (2.3%), and the remaining types (4.0%). This hydrometeor type classification provides observation-based insight for climate model diagnostics in representation of cloud phase and their microphysical characteristics. [ABSTRACT FROM AUTHOR]

The article focuses on a comprehensive collection of alloy phase diagrams for the binary systems. It presents the Silver-Lithium (Ag-Li) phase diagram based on the works wherein the (Ag) liquidus and solidus were assessed thermodynamically. It also highlights the Carbon-Manganese (C-Mn) phase diagram obtained through thermodynamic assessments.

Several diagrams is presented which explains the binary phase diagrams of alloys including silver-ytterbium (Ag-Yb), aluminum-cobalt (Al-Co), and aluminum-iodine (Al-I).

An Erratum to this paper has been published: https://doi.org/10.1134/S1024856023330023 [ABSTRACT FROM AUTHOR]

We have investigated the crystal, electronic, and magnetic structures of Mn5O8 by means of state-of-the-art density functional theory calculations and neutron powder diffraction (NPD) measurements. This compound stabilizes in the monoclinic structure with space group C2/m where the Mn ions are in the distorted octahedral and trigonal prismatic coordinations with oxygen atoms. The calculated structural parameters based on total energy calculations are found to be in excellent agreement with low temperature NPD measurements when we accounted for the correct magnetic structure and Coulomb correlation effect in the computation. Using fully relativistic generalized-gradient approximation with Hubbard U (GGA+U) we found that the magnetic ordering in Mn5O8 is A-type antiferromagnetic and the direction of the easy axis is [1 0 0] in agreement with susceptibility and NPD measurements. However, the calculation without the inclusion of Hubbard U leads to ferrimagnetic half metal as a ground state contradictory to experimental findings, indicating the presence of a strong Coulomb correlation effect in this material. The GGA calculation without the Coulomb correction effect itself is sufficient to reproduce the experimentally observed magnetic moments in various Mn sites. We found that Mn in this material exhibits mixed valence behavior with 2+ and 4+ oxidation states reflecting different magnetic moments in the Mn sites. We explored the electronic band characteristics using total, site-, and orbital-projected density of states which emphasized the mixed-valent nature of Mn. A dominant Mn 3d character of the density of states at Fermi energy is the origin for the metallic behavior of Mn5O8. The bond strength analysis based on the crystal orbital Hamiltonian population between constituents indicates strong anisotropy in the bonding behavior which results from the layered nature of its crystal structure. Our bonding analysis shows that there is a noticeable covalent bond between Mn 3d–O 2p states which stabilizes the observed low symmetric structure. Our experimental findings and theoretical predictions suggest that Mn5O8 can be classified as a strongly correlated mixed valent antiferromagnetic metal. [ABSTRACT FROM AUTHOR]

The article presents several updates on various alloy phase diagrams for binary systems. Topics discussed include the disagreement or inconsistencies among the thermodynamic models of boron-iron (B-FE) phase diagram, the thermodynamic assessment for the chromium-zirconium (Cr-Zr) phase diagram, and the phase diagram for the germanium-nickel (Ge-Ni) phase diagram.

Background and objectives Human hepatitis E virus ( HEV) is prevalent worldwide. Iatrogenic HEV has recently been identified based on the reports of transfusion-transmitted cases. The detection rate of HEV- RNA and seroprevalence of HEV-IgG/IgM have been regionally evaluated in Japan, and donor plasma collected in Hokkaido is currently screened by nucleic acid amplification testing. However, the detection rate of HEV- RNA in blood donors in Japan outside of Hokkaido has not been reported. Materials and Methods A total of 620 140 qualified donor plasma samples from Japanese regions excluding Hokkaido were tested for HEV- RNA (pools of 50 or 500) between 2004 and 2014. HEV- RNA-positive plasma bags were identified, and the HEV viral load, genotype and anti- HEV immunoglobulin (Ig)G/IgM were evaluated. Results The detection rate of HEV- RNA (pools of 50) was 1/15 075 and higher in eastern than in western Japan. All 36 HEV- RNA-positive samples were genotype 3 with viral load ranging from <1·69 to 7·22 log10 copies/ml. Conclusions Our detection rate of HEV- RNA in donor populations in Japan outside Hokkaido (1/15 075 donations) is generally lower than reported in Europe and lower than previously reported for Hokkaido (1/8173 donations). As methods varied, we cannot exclude that these differences are reflective of differing RNA detection limits. In contrast to Hokkaido where genotype 4 has been reported among blood donations, all our positive donations were genotype 3, which is less pathogenic. [ABSTRACT FROM AUTHOR]

Objective To determine whether the intrathecal concentrations of cytokines/chemokines are associated with, or influenced by, serum concentrations in patients with central neuropsychiatric systemic lupus erythematosus (NPSLE), and to ascertain whether the increased production of cytokines/chemokines intrathecally relative to serum levels is associated with the presence of central NPSLE. Methods 52 SLE patients (30 with central NPSLE and 22 with non-NPSLE), for whom the CSF and serum samples were obtained at the same time, were enrolled. 27 kinds of cytokine/chemokine concentrations other than IFN-α in the cerebrospinal fluid (CSF) and serum samples were measured by Bio-Plex Pro Assays. IFN-α concentration and anti-ribosomal P protein antibody (anti-P) titres in CSF and serum samples were measured by ELISA. Results The mean concentrations of IL-6, IL-8, IP-10, MCP-1, G-CSF and GM-CSF were higher in the CSF than in the sera, respectively, while the mean concentrations of other 22 cytokines/chemokines, including RANTES and IFN-α, in the CSF were much lower than those in the sera, respectively. Furthermore, the concentrations of IL-6, IL-8, IP-10, MCP-1 and G-CSF in the CSF of the 30 patients with NPSLE were significantly higher than in the 22 patients with non-NPSLE (p = 6.82 × 10−5, p = 0.00037, p = 0.0028, p = 0.00065, and p = 0.0001, respectively), while the concentration of GM-CSF in the CSF of the 30 patients with NPSLE was not significantly higher than in the 22 patients with non-NPSLE. Most importantly, the largest difference occurred in CSF IL-6 concentrations. A significant positive correlation between CSF anti-P titres and serum anti-P titres in 52 patients with SLE (r = 0.6316, p = 6.44 × 10−6) was found, while no significant positive correlation was observed between CSF levels and serum levels of each cytokine/chemokine in the 52 SLE patients. Conclusion In central NPSLE the production of IL-6, IL-8, IP-10, MCP-1 and G-CSF might take place in the central nervous system (CNS). These increased CSF cytokines/chemokines along with anti-P might have a prerequisite role in the pathogenesis of central NPSLE. [ABSTRACT FROM AUTHOR]

Highly migratory marine species can travel long distances and across entire ocean basins to reach foraging and breeding grounds, yet gaps persist in our knowledge of oceanic dispersal and habitat use. This is especially true for sea turtles, whose complex life history and lengthy pelagic stage present unique conservation challenges. Few studies have explored how these young at-sea turtles navigate their environment, but advancements in satellite technology and numerical models have shown that active and passive movements are used in relation to open ocean features. Here, we provide the first study, to the best of our knowledge, to simultaneously combine a high-resolution physical forcing ocean circulation model with long-term multi-year tracking data of young, trans-oceanic North Pacific loggerhead sea turtles during their 'lost years' at sea. From 2010 to 2014, we compare simulated trajectories of passive transport with empirical data of 1–3 year old turtles released off Japan (29.7–37.5 straight carapace length cm). After several years, the at-sea distribution of simulated current-driven trajectories significantly differed fromthat of the observed turtle tracks. These results underscore current theories on active dispersal by young oceanic-stage sea turtles and give further weight to hypotheses of juvenile foraging strategies for this species. Such information can also provide critical geographical information for spatially explicit conservation approaches to this endangered population. [ABSTRACT FROM AUTHOR]

The article offers information on Binary Alloy Phase Diagrams, a collection of alloy phase diagrams for 2159 binary systems and the recent information presents binary phase diagrams for various chemical alloys. These include Aluminium-Neodymium (Al-Nd) phase diagram, Aluminum-Vanadium (Al-V) phase diagram and Bismuth-Ytterbium (Bi-Yb) binary phase diagram.

The article discusses a review of binary phase diagrams designed to provide information on the binary phase diagrams for the Ag-Cl, Br-Pb, Br-Zn, C-Cu, Ce-Zr, Cl-Zn, Fe-Lu, Fe-Tm, Ga-V, Nd-Ti, Nd-Zr and Si-Ta systems that became available after 1990. The criteria for the selection of information for inclusion in the review are systems where no phase diagram was given in, complete diagrams substantially different from earlier version and partial diagrams that alter earlier version.