159 results on '"MACHADO, C. A."'
Search Results
2. Psychological impact of COVID-19 containment on CADASIL patients.
- Author
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Reyes, S., Jabouley, A., Alili, N., De Sanctis, M. H., Machado, C., Taleb, A., Herve, D., Dias-Gastellier, N., and Chabriat, H.
- Subjects
CEREBRAL small vessel diseases ,PSYCHOLOGICAL factors ,COVID-19 pandemic ,LIVING alone ,COVID-19 - Abstract
Introduction: COVID-19 restrictive containment was responsible for major psychological distress and alteration of quality of life (QoL) in the general population. Their impact in a group of patients having cerebral small vessel disease (SVD) and at high risk of stroke and disability was unknown. Objective: We aimed to determine the potential psychological impact of strict containment during the COVID-19 pandemic in a sample of CADASIL patients, a rare SVD caused by NOTCH3 gene mutations. Methods: Interviews of 135 CADASIL patients were obtained just after the end of the strict containment in France. Depression, QoL and negative subjective experience of the containment were analysed, as well as predictors of posttraumatic and stressor-related manifestations, defined as an Impact Event Scale-Revised score ≥ 24, using multivariable logistic analysis. Results: Only 9% of patients showed a depressive episode. A similar proportion had significant posttraumatic and stressor-related disorder manifestations independently associated only with socio-environment factors, rather than clinical ones: living alone outside a couple (OR 7.86 (1.87–38.32), unemployment (OR 4.73 (1.17–18.70)) and the presence of 2 or more children at home (OR 6.34 (1.35–38.34). Conclusion: Psychological impact of the containment was limited in CADASIL patients and did not appear related to the disease status. About 9% of patients presented with significant posttraumatic and stressor-related disorder manifestations which were predicted by living alone, unemployment, or exhaustion related to parental burden. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
3. El perfeccionamiento de la empresa socialista en la actualización del modelo socioeconómico cubano. Retos y posibilidades.
- Author
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Fabré Machado, C. Idalsis, Cabriales Saez, Yuniesky, and Díaz-Velis, Cheila Soris
- Subjects
SOCIAL development ,GOVERNMENT business enterprises ,STRUCTURAL design ,ECONOMIC development ,BUSINESS development - Abstract
Copyright of Revista El Directivo al Día is the property of Centro de Informacion y Gestion Tecnologica (CIGET) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
4. Percepción de dirigentes sindicales sobre prácticas asociadas a la Responsabilidad Social Empresarial.
- Author
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Rodríguez González, Diana Rosa, Fabré Machado, C. Idalsis, Rivas-Santos, Elianet, and Yamila Roque-Doval, C.
- Subjects
SOCIAL responsibility of business ,SOCIAL responsibility ,SOCIAL perception ,THEMATIC analysis ,GOVERNMENT business enterprises - Abstract
Copyright of Revista El Directivo al Día is the property of Centro de Informacion y Gestion Tecnologica (CIGET) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
5. Antimicrobial efficacy of in vitro and ex vivo photodynamic therapy using porphyrins against Moraxella spp. isolated from bovine keratoconjunctivitis.
- Author
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Seeger, M. G., Machado, C. S., Iglesias, B. A., Vogel, F. S. F., and Cargnelutti, J. F.
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MORAXELLA ,PHOTODYNAMIC therapy ,PORPHYRINS ,KERATOCONJUNCTIVITIS ,ZINC porphyrins ,METALLOPORPHYRINS ,BOS - Abstract
Infectious bovine keratoconjunctivitis (IBK) is an ocular disease affecting bovine herds worldwide, and it causes significant economic loss. The etiologic agent of IBK is considered to be Moraxella bovis, but M. ovis and M. bovoculi are frequently recovered of animals presenting clinical signs of IBK. The therapeutic measures available for its control have limited efficacy. Antimicrobial photodynamic therapy (aPDT) using porphyrins as photosensitizing molecules is an alternative method that can be used to reduce microbial growth. We evaluated the antibacterial activity of aPDT using two water-soluble tetra-cationic porphyrins (H
2 TMeP and ZnTMeP) against 22 clinical isolates and standard strains of Moraxella spp. in vitro and in an ex vivo model. For the in vitro assay, 4.0 µM of porphyrin was incubated with approximately 1.0 × 104 CFU/mL of each Moraxella sp. isolate and exposed to artificial light for 0, 2.5, 5, and 7.5 min. Next, 50 µL of this solution was plated and incubated for 24 h until CFU measurement. For the ex vivo assay, corneas excised from the eyeballs of slaughtered cattle were irrigated with Moraxella spp. culture, followed by the addition of zinc(II) porphyrin ZnTMeP (4.0 μM). The corneal samples were irradiated for 0, 7.5, and 30 min, followed by swab collection, plating, and CFU count. The results demonstrated the in vitro inactivation of the strains and clinical isolates of Moraxella spp. after 2.5 min of irradiation using ZnTMeP, reaching complete inactivation until 7.5 min. In the ex vivo experiment, the use of ZnTMeP resulted in the most significant reduction in bacterial concentration after 30 min of irradiation. These results encourage future in vivo experiments to investigate the role of metalloporphyrin ZnTMeP in the inactivation of Moraxella spp. isolates causing IBK. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
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6. Las redes sociales y su impronta en el quehacer de los directivos en Cuba.
- Author
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Fabré Machado, C. Idalsis and Rosa Rodríguez-González, Diana
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INFORMATION & communication technologies ,SOCIAL networks ,IMPERIALISM ,INTERNALIZATION (Social psychology) - Abstract
Copyright of Revista El Directivo al Día is the property of Centro de Informacion y Gestion Tecnologica (CIGET) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
7. Fibrotic alterations in human annulus fibrosus correlate with progression of intervertebral disc herniation.
- Author
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Castro, A. L., Ribeiro-Machado, C., Oliveira, C. M., Teixeira, G. Q., Neidlinger-Wilke, C., Pereira, P., Vaz, R., Barbosa, M. A., and Gonçalves, R. M.
- Published
- 2022
- Full Text
- View/download PDF
8. CONTEXTO EMPRESARIAL CUBANO Y CONTROL: ENTRE LO ESTRATÉGICOS Y LO OPERATIVO.
- Author
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Fabré-Machado, C. Idalsis and Riera-Vázquez, C. Celia Marta
- Abstract
Copyright of Revista El Directivo al Día is the property of Centro de Informacion y Gestion Tecnologica (CIGET) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
9. Spatial identification of hazardous segments on rural highways considering the interaction weather-pavement surface conditions using PKDE and NKDE.
- Author
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Machado, C. A. S., Albarracin, O. Y. E., Carvalho, F. S., Ho, L. L., Quintanilha, J. A., and Bemucci, L. L. B.
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SURFACE interactions ,GEOGRAPHIC information systems ,PAVEMENTS ,WEATHER ,ROADS - Abstract
The objectives of this study are to present a methodology for identifying high-crash density zones using geographical information systems and apply a kernel density estimation (KDE) for determining most hazardous road segments. Moreover, we connect weather information with the crash analysis to demonstrate the interactions between adverse weather conditions and the surface pavement condition (friction and texture) and apply their relationship to the crash frequencies. The motivation of this study was to identify mainly local regions where most crashes occur and to conduct interventions there, thus improving the safety of the studied segment of the highway. To develop this methodology and conduct the analysis, data of crashes of 7 years (2009-2015) occurring on a heavy-duty Brazilian highway were used. The findings demonstrate that when data of total crashes (e.g., rear-end collision, side-impact collision, sideswipe collision, head on collision, and rollover) are compared with those of skidding crashes, which are generally caused by wet pavements, the critical sections are essentially the same. This indicates that the wet pavement is a significant factor influencing crash occurrences. Therefore, solutions for asphaltic resurfacing that increase friction and aims to improve drainage have the potential to decrease the number of crashes. This study presents a spatial perspective to research on delineating hazardous road segments and the complex issue of how they can be measured. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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- View/download PDF
10. The global prevalence of apical periodontitis: a systematic review and meta‐analysis.
- Author
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Tibúrcio‐Machado, C. S., Michelon, C., Zanatta, F. B., Gomes, M. S., Marin, J. A., and Bier, C. A.
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PERIAPICAL periodontitis ,META-analysis ,SYSTEMATIC reviews ,CONE beam computed tomography ,PANORAMIC radiography - Abstract
Background: Apical periodontitis (AP) frequently presents as a chronic asymptomatic disease. To arrive at a true diagnosis, in addition to the clinical examination, it is mandatory to undertake radiographic examinations such as periapical or panoramic radiographs, or cone‐beam computed tomography (CBCT). Thus, the worldwide burden of AP is probably underestimated or unknown. Previous systematic reviews attempted to estimate the prevalence of AP, but none have investigated which factors may influence its prevalence worldwide. Objectives: To assess: (i) the prevalence of AP in the population worldwide, as well as the frequency of AP in all teeth, nontreated teeth and root filled teeth; (ii) which factors can modify the prevalence of AP. Methods: A search was conducted in the PubMed‐MEDLINE, EMBASE, Cochrane‐CENTRAL, LILACS, Google scholar and OpenGrey databases, followed by hand searches, until September 2019. Cross‐sectional, case–control and cohort studies reporting the prevalence of AP in humans, using panoramic or periapical radiograph or CBCT as image methods were included. No language restriction was applied. An adaptation of the Newcastle‐Ottawa Scale was used to evaluate the quality of the studies. A meta‐analysis was performed to determine the pooled prevalence of AP at the individual level. Secondary outcomes were the frequency of AP in all teeth, nontreated teeth and rootfilled teeth. Subgroup analyses using random‐effect models were carried out to analyse the influence of explanatory covariables on the outcome. Results: The search strategy identified 6670 articles, and 114 studies were included in the meta‐analysis, providing data from 34 668 individuals and 639 357 teeth. The prevalence of AP was 52% at the individual level (95% CI 42%–56%, I2 = 97.8%) and 5% at the tooth level (95% CI 4%–6%; I2 = 99.5%). The frequency of AP in root‐filled teeth and nontreated teeth was 39% (95% CI 36%–43%; I2 = 98.5%) and 3% (95% CI 2%–3%; I2 = 99.3%), respectively. The prevalence of AP was greater in samples from dental care services (DCS; 57%; 95% CI 52%–62%; I2 = 97.8%) and hospitals (51%; 95% CI 40%–63%; I2 = 95.9%) than in those from the general population (GP; 40%; 95% CI 33%–46%; I2 = 96.5%); it was also greater in people with a systemic condition (63%; 95% CI 56%–69%, I2 = 89.7%) compared to healthy individuals (48%; 95% CI 43%–53%; I2 = 98.3%). Discussion: The subgroup analyses identified explanatory factors related to the variability in the prevalence of AP. However, the high clinical heterogeneity and high risk of bias across the primary studies indicate that the findings must be interpreted with caution. Conclusions: Half of the adult population worldwide have at least one tooth with apical periodontitis. The prevalence of AP is greater in samples from the dental care services, but it is also high amongst community representative samples from the general population. The present findings should bring the attention of health policymakers, medical and dental communities to the hidden burden of endodontic disease in the population worldwide. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
11. Duration Models: The Effect of Firm and Location Characteristics on RBSO Firms' Survival.
- Author
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Conceição, Oscarina, Faria, Ana Paula, and Machado, C. Sofia
- Subjects
MUNICIPAL government ,WEIBULL distribution ,PROBABILITY theory ,PROPORTIONAL hazards models - Abstract
Existing literature has shown that research-based spin-off firms usually exhibit lower death risks than other startups. However, few studies have focused on the survival determinants of these particular firms. From a matched employer-employee data set this paper fills in this gap by providing evidence using a sample of RBSOs created in Portugal from 1979 until 2007 and observed until 2012. Specifically, we use duration analysis -- both accelerated failure time models and proportional hazard models - to investigate if firm characteristics and location characteristics play a role on these firms' survival. Results from the Weibull model show a positive impact of variables such as firm size and age on these firms' survival probability as well as the location of spin-offs in municipalities with high entry rates and low exit rates. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
12. Duration Models: The Effect of Firm and Location Characteristics on RBSO Firms’ Survival.
- Author
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Conceição, Oscarina, Faria, Ana Paula, and Machado, C. Sofia
- Abstract
Existing literature has shown that research-based spin-off firms usually exhibit lower death risks than other startups. However, few studies have focused on the survival determinants of these particular firms. From a matched employeremployee data set this paper fills in this gap by providing evidence using a sample of RBSOs created in Portugal from 1979 until 2007 and observed until 2012. Specifically, we use duration analysis – both accelerated failure time models and proportional hazard models - to investigate if firm characteristics and location characteristics play a role on these firms’ survival. Results from the Weibull model show a positive impact of variables such as firm size and age on these firms’ survival probability as well as the location of spin-offs in municipalities with high entry rates and low exit rates. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
13. A EDUCAÇÃO ENQUANTO EXPERIÊNCIA COMUNITÁRIA E A ESCOLA VIVA OLHO DO TEMPO: O CIRCULAR DE SABERES COMO PRÁTICA ALTERNATIVA INOVADORA.
- Author
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DE ALMEIDA, A. R., SILVA, S. B. DA, NASCIMENTO, G. A. DO, and MACHADO, C. J. S.
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COMMUNITY education ,PARTICIPANT observation ,DATA analysis ,QUALITATIVE research ,WORLDVIEW ,TRANSFORMATIVE learning - Abstract
Copyright of HOLOS is the property of Instituto Federal do Rio Grande do norte - IFRN and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
14. IL-22 increases the production of sFRP3 by FLS in inflammatory joint diseases.
- Author
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Resende, G. G., Machado, C. R. L., Rocha, M. A., Macedo, R. B. V., Filho, J. S. S. Bueno, Kakehasi, A. M., and Andrade, M. V.
- Published
- 2020
- Full Text
- View/download PDF
15. Aging and low-intensity exercise change oxidative biomarkers in brain regions and radiographic measures of femur of Wistar rats.
- Author
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Silveira, E. M. S., Santos, M. C. Q., da Silva, T. C. B., Silva, F. B. O., Machado, C. V., Elias, L., Kolberg, A., Kroth, A., and Partata, W. A.
- Published
- 2020
- Full Text
- View/download PDF
16. Hospital cardioprotegido, antípoda de la muerte súbita: Propuesta del Hospital General de Cienfuegos.
- Author
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Navarro Machado, C. Víctor R., García Escudero, Viviana C., Rodríguez Roque, María O., Falcón Hernández, Arelys, and Gómez Carcassés, Leonardo M.
- Abstract
Copyright of CorSalud is the property of Cardiocentro Ernesto Che Guevara and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
17. Complete sequence of a new bipartite begomovirus infecting Sida sp. in Northeastern Brazil.
- Author
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Macedo, M. A., Rêgo-Machado, C. M., Maliano, M. L., Rojas, M. R., Inoue-Nagata, A. K., and Gilbertson, R. L.
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BEGOMOVIRUSES ,MOSAIC viruses ,RESTRICTION fragment length polymorphisms ,SPECIES - Abstract
In Brazil, non-cultivated plants, especially weeds, are infected with a diversity of begomoviruses and often show striking golden mosaic symptoms. In the present study, leaves showing these symptoms were collected from Sida sp. plants in Guadalupe, Piaui State, Northeastern Brazil, in 2015 and 2016. PCR tests with degenerate primers revealed the presence of begomovirus DNA-A and DNA-B components. Restriction enzyme digestion of rolling circle-amplified DNA revealed fragments totaling ~5.2 kb, indicating infection by a bipartite begomovirus. The DNA-A and DNA-B components have a genome organization typical of New World (NW) bipartite begomoviruses and a common region of 220 nucleotides (nt) with 96% identity, indicating these are cognate components. Comparisons performed with the DNA-A sequence revealed the highest nt sequence identity (84%) with that of sida angular mosaic virus (SiAMV), whereas those performed with the DNA-B sequence revealed highest identity (77%) with that of sida chlorotic vein virus (SiCVV). In phylogenetic analyses, the DNA-A sequence was placed in a strongly supported clade with SiAMV and SiCVV from Piaui, whereas the DNA-B sequence was placed in a clade with SiCVV and corchorus mottle virus. Based on the current ICTV criteria for the demarcation of begomovirus species (<91% nt sequence identity for the DNA-A component), this is a member of a new species for which the name "Sida yellow golden mosaic virus" is proposed. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
18. Linac4 H- Source R&D: Cusp Free ICP and Magnetron Discharge.
- Author
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Lettry, J., Bertolo, S., Fantz, U., Guida, R., Kapusniak, K., Di Lorenzo, F., Machado, C., Mastrostefano, C., Minea, T., O’Neil, M., Neupert, H., Noll, D., Steyaert, D., and Thaus, N.
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PLASMA heating ,PLASMA sources ,MOLYBDENUM ,COEXTRACTION (Chemistry) ,ELECTRIC arc ,MONTE Carlo method - Abstract
The 2MHz radio-frequency inductively coupled plasma heating (ICP RF) of Linac4’s IS03 H
- source is more efficient without its octupole cusp in offset hallbach configuration. This was shown by Particle in cell Monte-Carlo (PIC-MC) simulation using the NINJA software [1] and confirmed by plasma characterization via optical emission spectroscopy [2,3], an easier plasma ignition is also anticipated. In this paper, we present preliminary results of an Alumina plasma chamber IS03 H- source [4] operated without magnetic cusp. Operation under monthly cesiation induces a slow evolution of the molybdenum cesiated surface correlated with an increase of the co-extracted electron yield. An improved stability of the extracted H- beam is achieved by compensating the Cs-losses. The high intensity option for Linac4 features an adaptation of BNL’s Magnetron. Simulation of this complex H2 -Cs arc discharge plasma, where electrons are emitted from a cesiated molybdenum cathode, requires characterization of the plasma impedance and knowledge of hydrogen and cesium densities. We present a measurement of plasma impedance over the range of discharge current, hydrogen and cesium-densities. [ABSTRACT FROM AUTHOR]- Published
- 2018
- Full Text
- View/download PDF
19. Determinants of Research-Based Spin-Offs Survival.
- Author
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Conceição, Oscarina, Faria, Ana Paula, and Machado, C. Sofia
- Subjects
ACADEMIC spin-outs ,NEW business enterprises ,CREATIVE ability in business ,ORGANIZATIONAL performance ,BUSINESS success - Abstract
Existing literature has shown that research-based spin-offs firms usually exhibit lower death risks than other start-ups. However, few studies have focused on the survival determinants of these particular firms. From a matched employer-employee data set this paper fills this gap by providing evidence using a sample of RBSOs created in Portugal from 1979 until to 2007 and observed until 2012. Specifically, we investigate if firm characteristics and location characteristics play a role on their survival. Our results show a positive impact on the probability of survival of these firms (such factors as firm size and age) as well as the location of spin-offs in municipalities with high entry rates and low exit rates. [ABSTRACT FROM AUTHOR]
- Published
- 2018
20. An Original DEM Bearing Model with Electromechanical Coupling.
- Author
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Machado, C., Baudon, S., Guessasma, M., Bourny, V., Fortin, J., Bouzerar, R., and Maier, P.
- Subjects
DISCRETE element method ,HERTZIAN contacts ,DEAD loads (Mechanics) ,DYNAMIC loads ,PHENOMENOLOGICAL theory (Physics) - Abstract
We have developped an original 2D modeling of bearings by Discrete Element Method (DEM). The mechanical behavior and the dynamic of a bearing is well reproduced. An electromechanical coupling is introduced to provide monitoring solutions. In practice, the mechanical state in real-time is usually unknown and existing numerical methods are restricted. Electromechanical coupling seems to be able to indirectly measure the dynamic loading of the bearing. This behavior leads to the development of a new monitoring method based on electrical signatures. The study proposes an original method of simulating the bearings to correlate dynamic mechanical state with electrical responses, over time. The bearing is seen as a polydisperse granular chain where rolling elements and cage components interact with a Hertzian contact model. Moreover, rings (and housing) are also taken into account using a cohesive model. Indeed, while many studies have been conducted on bearing simulation using FEM and multibody approaches, this discrete approach gives relevant informations on physical phenomena in the contact interface. One of our objectives is to investigate the sensitivity of the electrical measurement due to typical mounting. The ability of DEM to describe accurately the mechanical state of a bearing has been established by means of a comparison with FEM, of load distributions in a static case. In dynamic, the consequences associated with the flexibility of the bearing mounting (rigid and elastic rings) are studied with mechanical stresses acting in rings and with the load distribution. Also, by accessing dynamic stresses, this modeling opens certain possibilities on studies of damage and wear by providing the history of contact. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
21. Contemporary group alternatives for genetic evaluation of milk yield in small populations of dairy cattle.
- Author
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Pereira, R. J., Schenkel, F. S., Ventura, R. V., Ayres, D. R., El Faro, L., Machado, C. H. C., and Albuquerque, L. G.
- Abstract
In the present study, different random regression models, focussed on the nature of the effect of the contemporary group, fixed or random, were compared for genetic evaluation of test-day milk yield in dairy Gir breed, whose herds are characterised by relatively reduced numbers of cows. Cows were assigned to the same contemporary group if they were tested in the same herd, year and month. In one of the evaluated models, the contemporary group was investigated as a fixed effect and a clustering procedure was adopted to group herd-year subclasses in order to, at the end of the process, all contemporary groups contained at least three cows. The models were compared by the quality of fit, the accuracy of the predicted breeding values and their estimates of genetic parameters. The clustering procedure did not significantly improve the accuracy of predicted breeding values. Moreover, the fit to the data for this model was negatively affected. Therefore, this strategy should not be further implemented. The model including the herd-calving period effect and contemporary group treated as random effect showed similar characteristics to its equivalent, where the contemporary group was modelled as a fixed effect. However, the fit to the data for this model was slightly worse. Thus, the results suggest a random regression model including the herd-calving period effect and the fixed effect of contemporary group for the genetic evaluations of production traits in dairy Gir cattle. These findings could be extended to small dairy cattle populations whose herds are small-sized. Several small populations of cattle are important genetic resources for the milk production systems, mainly in the Tropics. Obtaining accurate evaluation of the genetic merit of the animals in these populations requires consideration of some particularities. We compare alternatives to include the contemporary group in the model for genetic evaluation and our results showed that consider the contemporary group as a fixed effect without clustering herds is a better option than clustering herds to increase the size of contemporary groups. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
22. Microorganisms in the ticks Amblyomma dissimile Koch 1844 and Amblyomma rotundatum Koch 1844 collected from snakes in Brazil.
- Author
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Ogrzewalska, M., Machado, C., Rozental, T., Forneas, D., Cunha, L. E., and de Lemos, E. R. S.
- Subjects
AMBLYOMMA ,SNAKES ,RICKETTSIACEAE ,CLASSIFICATION of insects - Abstract
Knowledge about ticks (Acari) and screening of ticks parasitizing various hosts are necessary to understand the epidemiology of tick‐borne pathogens. The objective of this study was to investigate tick infestations on snakes (Reptilia: Squamata: Serpentes) arriving at the serpentarium at the Institute Vital Brazil, Rio de Janeiro. Some of the identified ticks were individually tested for the presence of bacteria of the genera Rickettsia (Rickettsiales: Rickettsiaceae), Borrelia (Spirochaetales: Spirochaetaceae), Coxiella (Legionellales: Coxiellaceae), Bartonella (Rhizobiales: Bartonellaceae), Ehrlichia (Rickettsiales: Anaplasmataceae), Anaplasma (Rickettsiales: Anaplasmataceae), and Apicomplexa protozoa of the genera Babesia (Piroplasmida: Babesiidae) and Hepatozoon (Eucoccidiorida: Hepatozoidae). A total of 115 hard ticks (Ixodida: Ixodidae) were collected from 17 host individuals obtained from four Brazilian states. Two species of tick were identified: Amblyomma dissimile Koch 1844 (four larvae, 16 nymphs, 40 adults), and Amblyomma rotundatum Koch 1844 (12 nymphs, 43 adults). Rickettsia bellii was found in A. rotundatum and A. dissimile ticks and Rickettsia sp. strain Colombianensi, Anaplasma‐like and Hepatozoon sp. in A. dissimile ticks. Among the tested ticks, no DNA of Borrelia, Bartonella, Coxiella or Babesia was found. The present findings extend the geographic range of Rickettsia sp. strain Colombianensi in Brazil and provide novel tick–host associations. Two species of tick were collected from snakes in Brazil: Amblyomma dissimile Koch 1844 and Amblyomma rotundatum Koch 1844.Rickettsia bellii was found in A. rotundatum and A. dissimile ticks, and Rickettsia sp. strain Colombianensi, Anaplasma‐like and Hepatozoon sp. in A. dissimile ticks.No DNA of Borrelia, Bartonella, Coxiella or Babesia was found in the tested ticks. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
23. A METHOD TO DEFINE THE SPATIAL STATIONS LOCATION IN A CARSHARING SYSTEM IN SÃO PAULO – BRAZIL.
- Author
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Lage, M. O., Machado, C. A. S., Berssaneti, F., and Quintanilha, J. A.
- Subjects
CAR sharing ,AUTOMOTIVE transportation - Abstract
Sharing mobility systems have become part of a sociodemographic trend that has pushed shared modes from the fringe to the mainstream of the transportation systems. Carsharing is a mode of shared transport, where a service is offered in which several people share the access and use of a set of vehicles. This is a relatively new mode of urban transport, which gives users access for short periods of rental, thus providing the benefits of using private vehicles, while avoiding the inherent property charges of a vehicle. The objective of the article searches for the identification and selection of preferred areas in the São Paulo City (Brazil) to implement a prototype of a carsharing system. The adopted methodology of demand analysis identifies the spatial patterns of the intervening variables of socioeconomic information, transportation and land use, in order to understand the current panorama of the demand for transport in São Paulo. The analysis made it possible to identify and select preferred areas in São Paulo for the implementation of a prototype. The study indicated the most favorable places to receive the service stations to operate a carsharing system. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
24. A method to define the spatial stations location in a carsharing system in São Paulo -Brazil.
- Author
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Lage, M. O., Machado, C. A. S., Berssaneti, F., and Quintanilha, J. A.
- Subjects
CAR sharing ,TRANSPORTATION ,URBAN transportation - Abstract
Sharing mobility systems have become part of a sociodemographic trend that has pushed shared modes from the fringe to the mainstream of the transportation systems. Carsharing is a mode of shared transport, where a service is offered in which several people share the access and use of a set of vehicles. This is a relatively new mode of urban transport, which gives users access for short periods of rental, thus providing the benefits of using private vehicles, while avoiding the inherent property charges of a vehicle. The objective of the article searches for the identification and selection of preferred areas in the São Paulo City (Brazil) to implement a prototype of a carsharing system. The adopted methodology of demand analysis identifies the spatial patterns of the intervening variables of socioeconomic information, transportation and land use, in order to understand the current panorama of the demand for transport in São Paulo. The analysis made it possible to identify and select preferred areas in São Paulo for the implementation of a prototype. The study indicated the most favorable places to receive the service stations to operate a carsharing system. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
25. Pharmacotherapy follow-up: Role in active malaria surveillance in a travel medicine centre outside the transmission area in Brazil.
- Author
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Pedro, R. S., Brasil, P., Pina‐Costa, A., Machado, C. R., Damasceno, L. S., Daniel‐Ribeiro, C. T., and Guaraldo, L.
- Subjects
DRUG therapy for malaria ,ANTIMALARIALS ,DRUG resistance ,DRUG side effects ,PUBLIC health surveillance ,SEX distribution ,COMORBIDITY ,DISEASE relapse ,TREATMENT effectiveness - Abstract
What is known and objective Malaria is a potentially severe disease, widespread in tropical and subtropical areas. Apart from parasite drug resistance, which receives the largest share of attention, several factors directly influence the response to antimalarial treatment such as incorrect doses, adverse drug events, lack of adherence to treatment, drug quality and drug-drug interactions. Pharmacotherapy follow-up can be used to monitor and improve the effectiveness of treatment, prevent drug-related problems and ensure patient safety. The aim of this study was to describe the results of the implementation of pharmacotherapy follow-up of patients with malaria seen at a reference centre for malaria diagnosis and treatment (CPD-Mal) located in the city of Rio de Janeiro, an area without malaria transmission. Methods A descriptive study was conducted from January 2009 to September 2013 at the Instituto Nacional de Infectologia Evandro Chagas (INI) of the Fundação Oswaldo Cruz (Fiocruz). All malaria patients enrolled in the study were treated according to the Brazilian Malaria Therapy Guidelines. Data collected during pharmacotherapy follow-up were recorded in a standardized form. The variables included were age, gender, comorbidities, antimalarials and concomitant medications used, adverse drug reactions (ADR), clinical and parasitological cure times, and treatment outcomes classified as success, recurrence (recrudescence or relapse); and lost to follow-up. The ADR were classified by severity (DAIDS-NIH), organ system affected (WHO-ART) and likelihood to be caused by drugs (Naranjo scale). Results and discussion One hundred thirteen cases of malaria were included. Patients were aged between 13 and 66 years and the majority of them (75.2%) were male. Ninety-four ADR were observed, most classified as mild (85.1%), related to disorders of the gastrointestinal system (63.8%), such as nausea and vomiting, and assessed as 'possibly' caused by the antimalarial drugs (91.5%). The majority of clinical (90.9%) and parasitological (87.1%) cure occurred less than 72 hours after treatment initiation. Pharmacotherapy follow-up of malaria treatment by surveillance activities is therefore important regarding information about treatment outcomes as well as patient safety, resulting in better patient care and reducing the chance of relapses. The results underscore its use as a tool for monitoring adherence and drug resistance outside an endemic area. What is new and conclusion Pharmacotherapy follow-up should be considered a useful malaria surveillance tool that can be developed by reference centres for comprehensive health care assistance and monitoring of therapeutic resistance. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
26. Thermal adaptation strategies of the extremophile bacterium Thermus filiformis based on multi-omics analysis.
- Author
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Mandelli, F., Couger, M., Paixão, D., Machado, C., Carnielli, C., Aricetti, J., Polikarpov, I., Prade, R., Caldana, C., Paes Leme, A., Mercadante, A., Riaño-Pachón, D., and Squina, Fabio
- Subjects
MICROBIOLOGY of extreme environments ,THERMOPHILIC bacteria ,CARBOHYDRATE metabolism ,PHYSIOLOGICAL effects of heat - Abstract
Thermus filiformis is an aerobic thermophilic bacterium isolated from a hot spring in New Zealand. The experimental study of the mechanisms of thermal adaptation is important to unveil response strategies of the microorganism to stress. In this study, the main pathways involved on T. filiformis thermoadaptation, as well as, thermozymes with potential biotechnological applications were revealed based on omics approaches. The strategy adopted in this study disclosed that pathways related to the carbohydrate metabolism were affected in response to thermoadaptation. High temperatures triggered oxidative stress, leading to repression of genes involved in glycolysis and the tricarboxylic acid cycle. During heat stress, the glucose metabolism occurred predominantly via the pentose phosphate pathway instead of the glycolysis pathway. Other processes, such as protein degradation, stringent response, and duplication of aminoacyl-tRNA synthetases, were also related to T. filiformis thermoadaptation. The heat-shock response influenced the carotenoid profile of T. filiformis, favoring the synthesis of thermozeaxanthins and thermobiszeaxanthins, which are related to membrane stabilization at high temperatures. Furthermore, antioxidant enzymes correlated with free radical scavenging, including superoxide dismutase, catalase and peroxidase, and metabolites, such as oxaloacetate and α-ketoglutarate, were accumulated at 77 °C. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
27. Ghrelin plasma levels, gastric ghrelin cell density and bone mineral density in women with rheumatoid arthritis.
- Author
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Maksud, F. A. N., Kakehasi, A. M., Guimarães, M. F. B. R., Machado, C. J., and Barbosa, A. J. A.
- Published
- 2017
- Full Text
- View/download PDF
28. Structure and diversity of fishes in a freshwater and coastal subtropical lagoon.
- Author
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Ferreira, N. C., Guereschi, R. M., Machado, C., Lopes, C. A., and Nuñer, A. P. O.
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FISH communities ,FISH diversity ,FISH larvae ,FISH development ,FRESHWATER ecology ,LAGOONS - Abstract
This study examined the fish communities of Peri Lagoon in southern Brazil to aid in the development of an effective management plan because the area is under threat from human activities. Sampling of fish fauna, ichthyoplankton and limnological data were compared between sites, differing by habitat type and characteristics such as depth, substratum composition and vegetation type. Results were significantly related to site, with the highest diversity and abundance recorded at shallow vegetated sites. A total of 14 fish species were recorded throughout the lagoon, with the most abundant being Hyphessobrycon luetkenii. Of the 14 species, half were sampled at their larval stage, suggesting a healthy and protected system. Significantly more larvae and eggs were collected during colder months (autumn to winter) and at sites closer to stream flow, possibly owing to increased food sources and habitat protection. This study highlights the importance of Peri Lagoon as a nursery ground for a wide range of fish species, providing essential information for incorporation into the future protection of fish stocks throughout Brazil. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
29. Charm production in a strong magnetic field.
- Author
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Machado, C. S., Navarra, F. S., Noronha, J., de Oliveira, E. G., and Strickland, M.
- Subjects
MAGNETIC fields ,MESONS ,ENERGY levels (Quantum mechanics) ,BOUND states ,NUCLEAR models - Abstract
We discuss the effects of a strong magnetic field on B and D mesons, focusing on the changes of the energy levels and the masses of the bound states. Using the Color Evaporation Model we discuss the possible changes in the production of J/ψ and Y. We briefly comment the recent experimental data. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
30. Structural characterization of (Bi 1- x Gd x ) 14 W 2 O 27 ( x = 0.00 and 0.05) synthesized via mechano-thermal treatment.
- Author
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Santiago, R. T., Vieira, D. S., Biagio, R. L., Camargo, V. G., Machado, C. F. C., Fabián, M., da Silva, K. L., and Šepelák, V.
- Subjects
STOICHIOMETRY ,CHEMICAL precursors ,RIETVELD refinement ,GADOLINIUM compounds ,CHEMICAL synthesis - Abstract
Samples of (Bi1-xGdx)14W2O27(x= 0 and 0.05) compounds were prepared via a combination of mechanochemical and thermal treatments upon a Bi2O3/WO3/Gd2O3stoichiometric mixture of precursors. Phase evolution, as well as the determination of structural parameters in as-prepared compounds, were performed by XRD analysis. Rietveld refinement revealed that gadolinium ions are incorporated into the tetragonal structure of Bi14W2O27with preference to occupy octahedrally coordinated Bi3+sites. The Gd doping induced an increase in Bi sites coordination,i.e., the number of oxygens around Bi/Gd ions increased, which can be explained by the absence of 6s2lone pair electrons in gadolinium ions. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
31. The dental pulp stem cell niche based on aldehyde dehydrogenase 1 expression.
- Author
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Machado, C. V., Passos, S. T., Campos, T. M. C., Bernardi, L., Vilas‐Bôas, D. S., Nör, J. E., Telles, P. D. S., and Nascimento, I. L.
- Subjects
DENTAL pulp ,STEM cells ,ALDEHYDE dehydrogenase ,IMMUNOHISTOCHEMISTRY ,FLOW cytometry ,CELL membranes ,CD90 antigen ,NERVE fibers - Abstract
Aim To detect cells expressing the stem cell marker ALDH1 (aldehyde dehydrogenase1) in the pulp of human permanent teeth and to investigate the expression of ALDH1 in isolated dental pulp cells. Methodology Pulp tissue was collected and processed for immunohistochemistry to detect ALDH1-, STRO-1- and CD90-positive cells. In addition, cells were isolated and analysed by flow cytometry for ALDH1 activity and for the cell surface markers CD44, CD73, CD90, STRO-1 and CD45. Cells were also examined for multidifferentiation capacity. Within these cells, an ALDH1
+ cell subpopulation was selected and evaluated for multidifferentiation capacity. Results The immunohistochemistry analyses showed that ALDH1-, CD90- and STRO-1-positive cells were located mainly in the perivascular areas and nerve fibres of dental pulps. Cells on the fifth passage had high expression for CD44, CD73 and CD90, whereas moderate labelling was observed for STRO-1 and ALDH1 in flow cytometry analysis. On the same passages, cells were able to differentiate into osteogenic, adipogenic and chondrogenic lineages. The ALDH1+ cell subpopulation also demonstrated multilineage differentiation ability. Conclusions Dental pulp stem cells reside in the vicinity of blood vessels and nerve fibres, indicating the possible existence of more than one stem cell niche in dental pulps. Furthermore, ALDH1 was expressed by isolated dental pulp cells, which had mesenchymal stem cell characteristics. Thus, it can be suggested that ALDH1 may be used as a DPSC marker. [ABSTRACT FROM AUTHOR]- Published
- 2016
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- View/download PDF
32. JASAG: a gridification tool for agricultural simulation applications.
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Arroqui, M., Alvarez, J. Rodriguez, Vazquez, H., Machado, C., Mateos, C., and Zunino, A.
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APPLICATION software ,GRID computing ,DATA structures ,PARALLEL computers ,COMPUTER systems - Abstract
The Grid Computing paradigm aims to create a 'virtual' and powerful single computer with many distributed resources to solve resource intensive problems. The term 'gridification' involves the process of transforming a conventional application to run in a Grid environment. In that sense, the more automatic this process is, the easier is for developers with low expertise in parallel and distributed computing to take advantage of these resources. To date, many semiautomatic gridifiers were built to support different gridification approaches and application code structures or anatomies. Furthermore, agricultural simulation applications have a particular common anatomy based on biophysical entities, such as animals, crops, and pastures, which are updated by actions, such as growing animals, growing crops, and growing pastures, along simulation execution. However, this anatomy is not fully supported by any of the existing gridifiers. Thus, this paper presents Agricultural Simulation Applications Gridifier (ASAG), a method for easy gridification of agricultural simulation applications, and its Java implementation, named Java ASAG (JASAG). The main design drivers of JASAG are middleware independence, separation of business logic and Grid behavior, and performance increase. An experimental evaluation showing the feasibility of the gridification method and its implementation is also reported, which resulted in speedups of up to 25 by using a real agricultural simulation application. Copyright © 2014 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
33. Nocturnal blood pressure dipping in acute ischemic stroke.
- Author
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Sargento‐Freitas, J., Laranjinha, I., Galego, O., Rebelo‐Ferreira, A., Moura, B., Correia, M., Silva, F., Machado, C., Cordeiro, G., and Cunha, L.
- Subjects
BLOOD pressure ,HEALTH outcome assessment ,STROKE treatment ,THROMBOLYTIC therapy ,DOPPLER effect ,ANGIOGRAPHY - Abstract
Objectives We aim to assess the impact of early nocturnal blood pressure ( BP) variation in the functional outcome of patients after an acute ischemic stroke. Materials and methods We included consecutive stroke patients treated with intravenous thrombolysis ( IVrt PA) in a tertiary stroke center. BP measurements were performed at regular intervals throughout day and night during the first 48 h after stroke onset, and subjects were divided into four dipping categories (extreme dippers, dippers, non-dippers, and reverse dippers). Recanalization was assessed by transcranial color-coded Doppler and/or angiographic CT. Hemorrhagic transformation was evaluated at 24 h follow-up CT scan. Functional outcome was evaluated at 3 months after stroke using the modified Rankin Scale. Results A total of 304 patients were included, mean age 72.80 ± 11.10 years. After 24 h of systolic BP monitoring, 30.59% were classified as reverse dippers, 39.14% as non-dippers, 19.10% as dippers, and 11.18% as extreme dippers. Multivariate analysis did not show an independent association of any dipping class with 3-month functional outcome. Hemorrhagic transformation was not uniform between dipping classes: 25.81% for reverse dippers, 14.29% for non-dippers, 15.52% for dippers, and 5.88% for extreme dippers, P = 0.033. Conclusions Nocturnal BP dipping pattern is not associated with functional outcome at 3 months in acute stroke patients treated with IVrt PA. Hemorrhagic transformation was more frequent in reverse dippers. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
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34. Evaluation of the Implementation of Good Handling Practices in Food and Beverage Areas of Hotels.
- Author
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SERAFIM, A. L., HECKTHEUER, L. H. R., STANGARLIN-FIORI, L., MEDEIROS, L. B., MARTELLO, L., and MACHADO, C. E.
- Subjects
FOOD handling safety measures ,FOOD safety research ,HOUSEHOLD sanitation ,BEVERAGE microbiology ,HOTEL food service - Abstract
Because of the major international-level events that have recently been held in Brazil, concerns about the sensory and hygienic-sanitary conditions of food have increased. The objective of this study was to evaluate the implementation of good handling practices in food and beverage areas of hotels, with and without outsourced professional intervention. We evaluated 19 food and beverage areas in hotels in Porto Alegre, Rio do Sul, Brazil, using a checklist that was developed by a municipal surveillance team based on existing laws for good handling practices. The evaluation was done by a skilled professional in the food safety area on two occasions, at the beginning of the study (January to May 2013) and at the end (July to November 2014), and the establishments were classified as good, regular, or poor. After the baseline evaluation, an action plan listing the noncompliance found at each location was given to those responsible for the establishments, and a period of 1 year 6 months was stipulated for improvements to be made. In the repeat evaluation, those responsible for the establishments were asked whether they had hired an outsourced professional to assist them in the improvements. The hotels showed improvement during the repeat evaluation, but a significant increase in the percentage of overall adequacy was seen only in the food and beverages areas of the 12 hotels that used the intervention of an outsourced professional. The better percentage of adequacy in establishments with outsourced professional intervention underlines the importance of an external and impartial view of routine activities in the implementation of good handling practices. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
35. Charm production in a strong magnetic field.
- Author
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Machado, C. S., Navarra, F. S., Noronha, J., de Oliveira, E. G., and Strickland, M.
- Subjects
MAGNETIC fields ,MESONS ,NUCLEAR energy ,BOUND states ,EVAPORATION model (Nuclear physics) ,HEAVY ion collisions - Abstract
We discuss the effects of a strong magnetic field on B and D mesons, focusing on the changes of the energy levels and the masses of the bound states. Using the Color Evaporation Model we discuss the possible changes in the production of Ј/Ψ and γ. We briefly comment the recent experimental data. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
36. Processing of gadolinium–iron garnet under non-equilibrium conditions.
- Author
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Zanatta, S. C., Ivashita, F. F., da Silva, K. L., Machado, C. F. C., and Paesano Jr., A.
- Abstract
We have investigated the mechanosynthesis of gadolinium iron garnet (GdIG) by high-energy ball-milling of 3.(Gd
2 O3 ) + 10.(α -Fe) followed by thermal annealing conducted at moderate temperatures (1100 °C). The samples were characterized by X-ray diffraction and Mossbauer spectroscopy in order to determine the influence of the milling time on the final products. For as-milled samples the results revealed the enlargement of the magnetic component belonging to iron and a discrete paramagnetic component. The formation of a garnet phase was observed in all as-annealed samples treated at 1100 °C for 6 h in quantities proportional to the time of grinding the precursors. Evidently, high-energy ball milling of Gd2 O3 +α -Fe powders is an important step in GdIG synthesis by a ceramic method. Single-phase garnet is observed for the samples milled for 12 and 24 h treated at 1100 °C for 6 h. [ABSTRACT FROM AUTHOR]- Published
- 2014
- Full Text
- View/download PDF
37. Estimates of genetic parameters for growth traits in Brahman cattle using random regression and multitrait models.
- Author
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Bertipaglia, T. S., Carreño, L. O. D., Aspilcueta-Borquis, R. R., Boligon, A. A., Farah, M. M., Gomes, F. J., Machado, C. H. C., Rey, F. S. B., and da Fonseca, R.
- Subjects
CATTLE development ,CATTLE genetics ,CATTLE quality ,REGRESSION analysis ,STATISTICAL correlation - Abstract
Random regression models (RRM) and multitrait models (MTM) were used to estimate genetic parameters for growth traits in Brazilian Brahman cattle and to compare the estimated breeding values obtained by these 2 methodologies. For RRM, 78,641 weight records taken between 60 and 550 d of age from 16,204 cattle were analyzed, and for MTM, the analysis consisted of 17,385 weight records taken at the same ages from 12,925 cattle. All models included the fixed effects of contemporary group and the additive genetic, maternal genetic, and animal permanent environmental effects and the quadratic effect of age at calving (AAC) as covariate. For RRM, the AAC was nested in the animal's age class. The best RRM considered cubic polynomials and the residual variance heterogeneity (5 levels). For MTM, the weights were adjusted for standard ages. For RRM, additive heritability estimates ranged from 0.42 to 0.75, and for MTM, the estimates ranged from 0.44 to 0.72 for both models at 60, 120, 205, 365, and 550 d of age. The maximum maternal heritability estimate (0.08) was at 140 d for RRM, but for MTM, it was highest at weaning (0.09). The magnitude of the genetic correlations was generally from moderate to high. The RRM adequately modeled changes in variance or covariance with age, and provided there was sufficient number of samples, increased accuracy in the estimation of the genetic parameters can be expected. Correlation of bull classifications were different in both methods and at all the ages evaluated, especially at high selection intensities, which could affect the response to selection. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
38. New record of African White-backed Vulture (Gyps africanus) in Europe.
- Author
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Godino, A. and Machado, C.
- Subjects
VULTURE mortality ,WILDLIFE conservation ,BIOLOGICAL stations - Abstract
The article discusses findings of an observatory study at the Biological Station of Garducho in Portugal, which reveals the presence of Eurasian Griffon vultures landing at a cow carcass.
- Published
- 2015
- Full Text
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39. Terrigeneous material supply to the Peruvian central continental shelf (Pisco 14° S) during the last 1100 yr: paleoclimatic implications.
- Author
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Zuluaga, F. Briceño, Sifeddine, A., Caquineau, S., Cardich, J., Salvatteci, R., Gutierrez, D., Ortlieb, L., Velazco, F., Boucher, H., and Machado, C.
- Abstract
In the Eastern Pacific, lithogenic input to the ocean is a response of the atmospheric and ocean system variability and their teleconnections over different timescales. Atmospheric (e.g., wind fields, precipitation), hydrological (e.g., fresh water plumes) and oceanic (e.g., currents) conditions determine the transport mode and the amount of lithogenic material transported from the continent to the continental shelf. Here, we present the grain size distribution of a composite record of two laminated sediment cores retrieved in the Peruvian continental shelf, covering the last ~ 1100 yr at subdecadal to centennial time-series resolution. We then discuss the paleo-environmental significance and the climatic mechanisms involved. Four grain size modes were identified. Two are linked to aeolian inputs (M3: 53.0 μm and M4: 90.8 μm on average), the third is interpreted as a marker of sediment discharge (M2: 9.4 μm on average), and the last is without an associated origin (M1: ~ 3 μm). The coarsest components (M3 and M4) dominated during the Medieval Climate Anomaly (MCA) and Current Warm Period (CWP) periods, suggesting that aeolian transport increased as consequence of wind stress intensification. In contrast, M2 displays an opposite behavior, exhibiting an increase in fluvial terrigenous input during the Little Ice Age (LIA), in response to more humid conditions. Comparison with other South American paleoclimate records indicates that the observed changes are driven by interactions between meridional displacement of the Intertropical convergence zone (ITCZ) and of the South Pacific Sub-tropical High (SPSH) at decadal and centennial time scales. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
40. Evaluation of pretransplant influenza vaccination in hematopoietic SCT: a randomized prospective study.
- Author
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Ambati, A, Boas, L S V, Ljungman, P, Testa, L, de Oliveira, J F, Aoun, M, Colturato, V, Maeurer, M, and Machado, C M
- Subjects
HEMAGGLUTININ ,INFLUENZA prevention ,INFLUENZA vaccines ,RANDOMIZATION (Statistics) ,RANDOMIZED controlled trials ,HEMATOPOIETIC stem cell transplantation - Abstract
Pretransplant influenza vaccination of the donor or allogeneic hematopoietic SCT (HSCT) candidate was evaluated in a randomized study. One hundred and twenty-two HSCT recipients and their donors were assigned to three randomization groups: no pretransplant vaccination (n=38), donor pretransplant vaccination (n=44) or recipient pretransplant vaccination (n=40). Specific IgG was assessed by both hemagglutinin inhibition (HI) and, in 57 patients, by an indirect influenza-specific ELISA at specified times after HSCT. Vaccinated donors had seroprotective HI titers for Ags H1 and H3 (P<0.001) compared with the other groups at the time of donation. The titers against H1 (P=0.028) and H3 (P<0.001) were highest in the pretransplant recipient vaccination group until day 180 after transplantation. A significant difference was found in the specific Ig levels against pandemic H1N1 at 6 months after SCT (P=0.02). The mean IgG levels against pandemic H1N1 and generic H1N1 and H3N2 were highest in the pretransplant recipient vaccination group. We conclude that pretransplant recipient vaccination improved the influenza-specific seroprotection rates. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
41. OCCURRENCE OF BILATERAL OVARIAN TERATOMA IN BUFFALO -- CASE REPORT.
- Author
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Machado, C. C., Pereira, W. L. A., Rolim Filho, S. T., Aguirra, L. R. V. M., Monger, S. G. B., and Vale, W. G.
- Subjects
WATER buffalo ,TERATOMA ,TUMORS in animals ,VETERINARY histopathology ,DISEASES - Abstract
Copyright of Archives of Veterinary Science is the property of Archives of Veterinary Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2015
42. Cambios en el Acople Neurovascular Inducidos por el Zolpidem en el Estado Vegetativo Persistente: Estudio de RMN funcional.
- Author
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Rodríguez-Rojas, R., Machado, C., Carballo, M., Estévez, M., and Chinchilla, M.
- Published
- 2013
- Full Text
- View/download PDF
43. Fallbeispiel Verkehrsunfall, Kind beteiligt.
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Machado, C.
- Published
- 2013
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44. Fallbeispiel Psychiatrische Einweisung.
- Author
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Machado, C.
- Published
- 2013
- Full Text
- View/download PDF
45. Fallbeispiel KTW-Einweisung liegend, schlechter Allgemeinzustand.
- Author
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Machado, C.
- Published
- 2013
- Full Text
- View/download PDF
46. Fallbeispiel Vermutlich Reanimation.
- Author
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Machado, C.
- Published
- 2013
- Full Text
- View/download PDF
47. Fallbeispiel Gynäkologischer Notfall.
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Machado, C.
- Published
- 2013
- Full Text
- View/download PDF
48. Fallbeispiel Chirurgischer Notfall/häuslicher Sturz.
- Author
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Machado, C.
- Published
- 2013
- Full Text
- View/download PDF
49. Fallbeispiel Krampfanfall.
- Author
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Machado, C.
- Published
- 2013
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50. Fallbeispiel Unklare Schmerzen, Hausarzt war vor Ort.
- Author
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Machado, C.
- Published
- 2013
- Full Text
- View/download PDF
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