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Nocturnal blood pressure dipping in acute ischemic stroke.
- Source :
- Acta Neurologica Scandinavica; Nov2015, Vol. 132 Issue 5, p323-328, 6p
- Publication Year :
- 2015
-
Abstract
- Objectives We aim to assess the impact of early nocturnal blood pressure ( BP) variation in the functional outcome of patients after an acute ischemic stroke. Materials and methods We included consecutive stroke patients treated with intravenous thrombolysis ( IVrt PA) in a tertiary stroke center. BP measurements were performed at regular intervals throughout day and night during the first 48 h after stroke onset, and subjects were divided into four dipping categories (extreme dippers, dippers, non-dippers, and reverse dippers). Recanalization was assessed by transcranial color-coded Doppler and/or angiographic CT. Hemorrhagic transformation was evaluated at 24 h follow-up CT scan. Functional outcome was evaluated at 3 months after stroke using the modified Rankin Scale. Results A total of 304 patients were included, mean age 72.80 ± 11.10 years. After 24 h of systolic BP monitoring, 30.59% were classified as reverse dippers, 39.14% as non-dippers, 19.10% as dippers, and 11.18% as extreme dippers. Multivariate analysis did not show an independent association of any dipping class with 3-month functional outcome. Hemorrhagic transformation was not uniform between dipping classes: 25.81% for reverse dippers, 14.29% for non-dippers, 15.52% for dippers, and 5.88% for extreme dippers, P = 0.033. Conclusions Nocturnal BP dipping pattern is not associated with functional outcome at 3 months in acute stroke patients treated with IVrt PA. Hemorrhagic transformation was more frequent in reverse dippers. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00016314
- Volume :
- 132
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Acta Neurologica Scandinavica
- Publication Type :
- Academic Journal
- Accession number :
- 110119115
- Full Text :
- https://doi.org/10.1111/ane.12402