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Background: In clinical practice, family medication history is not routinely assessed as part of a patient's family health history (FHH). The information is self-reported and can depend on the individual's subjective perception. To illustrate how pharmacogenetic (PGx) testing results could be used to validate self-reported family medication history on drug-related problems (DRP), as well as to inform medication-related decisions, we herein present a case involving ten members of the same family. Case Presentation: Prior to a planned surgery, a preemptive PGx panel test was performed for a nine-year-old girl due to self-reported family medication history. The PGx panel test was also performed for her three siblings, parents, and grandparents. The focus was directed to the paternal grandmother, as she reported DRP from the hypnotic agent propofol, and to the maternal grandmother, as she described DRP after the administration of codeine and tramadol. A commercial PGx panel test of 100 variations in 30 different genes was conducted and analyzed focusing on genetic variants in cytochrome P450 enzyme 2B6 (CYP2B6), and CYP2D6 as they are involved in the biotransformation of propofol and the bioactivation of codeine and tramadol, respectively. The girl was identified as (1) CYP2B6 intermediate metabolizer (IM) with reduced enzyme activity and (2) CYP2D6 poor metabolizer (PM) with no enzyme activity. Regarding the planned surgery, it was recommended (1) to carefully titrate propofol dosage with increased monitoring of potential DRP and (2) to avoid opioids whose activation is mediated by CYP2D6 (e.g. codeine and tramadol). Further PGx testing revealed (1) the paternal grandmother as CYP2B6 normal metabolizer (NM) and (2) the maternal grandmother as CYP2D6 NM. Conclusion: The original trigger for PGx testing was the self-reported, conspicuous family medication history of DRP reported by the grandmothers. However, the girl's genotype predicted phenotypes of CYP2B6 IM and CYP2D6 PM, differed from the grandmothers'. With this exemplary case, we propose that hereditary concerns based on self-reported information on DRP should be verified by a PGx panel test, when the respective drug exhibits a PGx association. Also, the girl's PGx testing results provided important medication recommendations, which were considered perioperatively by the anesthetist suggesting to use PGx testing results preemptively to inform medication-related decisions. [ABSTRACT FROM AUTHOR]

"Those who cannot remember the past are condemned to repeat it." This maxim underscores the importance of historical awareness in medicine, particularly for obstetricians and gynecologists (ObGyns). ObGyns significantly impact societal health through their care for pregnant women, fetuses, and newborns, uniquely positioning them to advocate for health initiatives with lasting societal benefits. Despite its importance, the history of medicine is underrepresented in medical curricula, missing opportunities to foster critical thinking and ethical decision-making. In today's climate of threatened reproductive rights, vaccine misinformation, and harmful ideologies, it is imperative for ObGyns to champion comprehensive historical education. The history of medicine, particularly in relation to societal issues – such as racism, discrimination, genocides, pandemics, and wars – provides valuable context for addressing challenges like maternal mortality, reproductive rights, vaccine hesitancy, and ethical issues. Understanding historical milestones and notable ethical breaches, such as the Tuskegee Study and the thalidomide tragedy, informs better practices and safeguards patient rights. Technological advancements in hygiene, antibiotics, vaccines, and prenatal care have revolutionized the field, yet contemporary ObGyns must remain vigilant about lessons learned from past challenges and successes. Integrating historical knowledge into medical training enhances clinical proficiency and ethical responsibility, fostering innovation and improving health outcomes. By reflecting on historical achievements and their impacts, current and future ObGyns can advance the field, ensuring comprehensive and ethically sound approaches to patient care. This paper highlights the crucial role of historical knowledge in shaping modern ObGyn practices, advocating for its integration into medical education to address contemporary health challenges and ethical considerations. [ABSTRACT FROM AUTHOR]

This document is an editorial for the 30th anniversary edition of the journal "Environment & History." The editorial reflects on the history and achievements of the journal since its founding in 1994. It highlights the journal's global coverage, commitment to interdisciplinary research, and efforts to promote equality, diversity, and inclusion in the field of environmental history. The editorial also introduces the contents of the special anniversary issue, which includes articles on various regions and topics, showcasing the scope and range of environmental history. The document concludes with a discussion of the future direction of the journal, emphasizing the importance of diverse perspectives and interdisciplinary collaboration. [Extracted from the article]

Spatially divergent natural selection can drive adaptation to contrasting environments and thus the evolution of ecotypes. In perennial plants, selection shapes life history traits by acting on subsequent life stages, each contributing to fitness. While evidence of adaptation in perennial plants is common, the expression of life history traits is rarely characterized, limiting our understanding of their role in adaptive evolution. We conducted a multi‐year reciprocal transplant experiment with seedlings from low and high elevation populations of the alpine carnation Dianthus carthusianorum to test for adaptation linked to contrasting climates and inferred specific contributions of early life stages to fitness. We assessed genotype by environment interactions in single fitness components, applied matrix population models to achieve an integrated estimate of fitness through population growth rates, and performed trade‐off analyses to investigate the advantage of alternate life history traits across environments. We found evidence of genotype by environment interactions consistent with elevational adaptation at multiple stages of the early life cycle. Estimates of population growth rates corroborated a strong advantage of the local genotype. Early reproduction and survival are alternate major contributors to adaptation at low and high elevation, respectively, and are linked by trade‐offs that underlie the evolution of divergent life history traits across environments. While these traits have a strong genetic basis, foreign populations express co‐gradient plasticity, reflecting the adaptive strategy of the local populations. Our study reveals that selection associated to climate has driven the evolution of divergent life histories and the formation of elevational ecotypes. While the high energy environment and strong competition favor investment in early reproduction at low elevation, limiting resources favor a more conservative strategy relying on self‐maintenance at high elevation. The co‐gradient plasticity expressed by high‐elevation populations may facilitate their persistence under warming climatic conditions. [ABSTRACT FROM AUTHOR]

In a bold move, Josie Rourke reimagined Bernard Shaw's Saint Joan for the 2016 audience at the Donmar Warehouse, setting it against the backdrop of today's financial world. She transported Joan from the medieval battlefield to a modern corporate boardroom, turning historical drama into a commentary on financialization. Through this lens, Rourke's production responds with Shaw's paradoxical sense of history, characterized by a skepticism toward short-term trends, yet with an underlying optimism for long-term human progress driven by imagination. By examining egg futures and stock markets, this article adopts an interdisciplinary approach to position theatrical work within the realm of economics, an endeavor that may offer a literary framework of humanity when contemplating our current economic landscape. [ABSTRACT FROM AUTHOR]

Copyright of Turkish History Education Journal (TUHED) is the property of Ahmet Simsek and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The paper is a review of literature on the historical relevance of African traditional song texts from the perspective of new historicism. It sides with the argument that the traditional history-making criterion, historiography, is not as factual or faithful in history-making as historians often suggest. It further supports the views that history is an imaginative text and literature (imaginative literature) a text of history; African traditional song texts, though literary texts, are reliable sources of history; and that oral tradition is a good source of history and complements written sources of history. In the paper, copious literature on these arguments is reviewed. It is found that literature opining that traditional song texts are reliable sources of history and are at once literary and historical texts abound in scholarship. It is also found that scholarship is replete with literature contesting historiography's claim to faithful and factual recording of history. It concludes that as literary texts, African traditional song texts are weaved with materials drawn from society and, therefore, reflect the yearnings, experiences, and outlook of the society at the various historical moments and trajectories, making them not only historical texts but also good sources of history. [ABSTRACT FROM AUTHOR]

Professional sport is a central element of our daily entertainment that contributes to shaping us individually and bonding us collectively: it provides us with shared 'historic' moments. This article is interested in these moments, and how the field of sports generates them, by asking the following questions: (1) has the frequency of 'historic moments' changed over time, and (2) is the way we make sports history consistent throughout the years? We conducted a temporal analysis of newspaper and magazine articles (n = 1062) published in France (Le Monde, l'Équipe) and in the United States (USA Today, Sports Illustrated) during three time periods in the 21st century (2003, 2010, 2019). Our results show that: (1) as time passes, 'historic' moments occur more frequently; (2) sporting history is increasingly linked to social dimensions; and (3) statistical performances continue to mark history above all else. Although performance-based achievements are consistently celebrated, sporting history cannot be separated from our collective social existence, and the currents therein. We show that the act of making sports history is also bound to the normative, social, and cultural history of a society. [ABSTRACT FROM AUTHOR]

This essay explores the purpose and significance of teaching the history of architecture. It argues that studying history is not just about understanding the past, but also about fathoming and debating the present. The essay emphasizes the importance of engaging with newer ways of inquiry and creative working with historicity to better understand architecture and its representations. It also highlights the demands of teaching history in a time when certain architectural elements are often read through religious or ideological lenses. The essay concludes by emphasizing the need to ask good questions and use history to debate design and architectural choices. [Extracted from the article]

This essay highlights the author's methodology for taking a feminist approach to doing oral history at a large university—particularly her efforts to involve the wider university community in the project of creating an inclusive and multi-perspectival institutional history. This essay is part of a PHR forum on the theme of "Personal Reflections on Feminist Historical Methods," with additional essays by Judy Tzu-Chun Wu, Y. Yvon Wang, and Natalia Mehlman Petrzela. The forum is part of a larger PHR special issue, Feminist Histories. [ABSTRACT FROM AUTHOR]

Copyright of Annals of the Faculty of Arts is the property of Ain Shams University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aedes aegypti, the vector for dengue, chikungunya, yellow fever, and Zika, poses a growing global epidemiological risk. Despite extensive research on Ae. aegypti's life history traits and behavior, critical knowledge gaps persist, particularly in integrating these findings across varied experimental contexts. The plasticity of Ae. aegypti's traits throughout its life cycle allows dynamic responses to environmental changes, yet understanding these variations within heterogeneous study designs remains challenging. A critical aspect often overlooked is the impact of using lab-adapted lines of Ae. aegypti, which may have evolved under laboratory conditions, potentially altering their life history traits and behavioral responses compared to wild populations. Therefore, incorporating field-derived populations in experimental designs is essential to capture the natural variability and adaptability of Ae. aegypti. The relationship between larval growing conditions and adult traits and behavior is significantly influenced by the specific context in which mosquitoes are studied. Laboratory conditions may not replicate the ecological complexities faced by wild populations, leading to discrepancies in observed traits and behavior. These discrepancies highlight the need for ecologically relevant experimental conditions, allowing mosquito traits and behavior to reflect field distributions. One effective approach is semi-field studies involving field-collected mosquitoes housed for fewer generations in the lab under ecologically relevant conditions. This growing trend provides researchers with the desired control over experimental conditions while maintaining the genetic diversity of field populations. By focusing on variations in life history traits and behavioral plasticity within these varied contexts, this review highlights the intricate relationship between larval growing conditions and adult traits and behavior. It underscores the significance of transstadial effects and the necessity of adopting study designs and reporting practices that acknowledge plasticity in adult traits and behavior, considering variations due to larval rearing conditions. Embracing such approaches paves the way for a comprehensive understanding of contextual variations in mosquito life history traits and behavior. This integrated perspective enables the synthesis of research findings across laboratory, semi-field, and field-based investigations, which is crucial for devising targeted intervention strategies tailored to specific ecological contexts to combat the health threat posed by this formidable disease vector effectively. [ABSTRACT FROM AUTHOR]

While prior research suggests that ventures not yet present in a given geographic community might threaten reflective aspects of community identity (i.e. materiality and rhetoric), it has yet to explain the divergent outcomes they might engender. In this article, we develop a comparative case study of communities where recreational cannabis dispensaries were founded and underlaid a noticeably different effect on identity reflections. Our findings suggest that different threat interpretations—founded in communal characterizations of history—spur theoretically similar yet descriptively different processes through which these elements co-evolve. Furthermore, these processes involve a wide range of actors and occur irrespective of the venture's ultimate influence on reflections of community identity. [ABSTRACT FROM AUTHOR]

Background: SELENON-related myopathy (SELENON-RM) is a rare congenital myopathy characterized by slowly progressive axial muscle weakness, rigidity of the spine, scoliosis, and respiratory insufficiency. Laminin-a2-related muscular dystrophy (LAMA2-MD) has a similar clinical phenotype, which ranges from severe, early-onset congenital muscular dystrophy type 1A (MDC1A) to milder forms presenting as childhood- or adult-onset limb-girdle type muscular dystrophy. The first 1.5-year natural history follow-up showed that 90% of the patients had low bone quality, respiratory impairments were found in all SELENON-RM and most of the LAMA2-MD patients, and many had cardiac risk factors. However, further extensive knowledge on long-term natural history data, and clinical and functional outcome measures is needed to reach trial readiness. Therefore, we extended the natural history study with 3- and 5-year follow-up visits (Extended LAST STRONG). Methods: The Extended LAST STRONG is a long-term natural history study in Dutch-speaking patients of all ages diagnosed with genetically confirmed SELENON-RM or LAMA2-MD, starting in September 2023. Patients visit our hospital twice over a period of 2 years to complete a 5-year follow up from the initial LAST-STRONG study. At both visits, they undergo standardized neurological examination, hand-held dynamometry (age ≥ 5 years), functional measurements, muscle ultrasound, respiratory assessments (spirometry, maximal inspiratory and expiratory pressure, sniff nasal inspiratory pressure; age ≥ 5 years), Dual-energy X-ray absorptiometry (DEXA-)scan (age ≥ 2 years), X-ray of the left hand (age ≤ 17 years), lower extremity MRI (age ≥ 10 years), accelerometry for 8 days (age ≥ 2 years), and questionnaires (patient report and/or parent proxy; age ≥ 2 years). All examinations are adapted to the patient's age and functional abilities. Disease progression between all subsequent visits and relationships between outcome measures will be assessed. Discussion: This study will provide valuable insights into the 5-year natural history of patients with SELENON-RM and LAMA2-MD and contribute to further selecting relevant and sensitive to change clinical and functional outcome measures. Furthermore, this data will help optimize natural history data collection in clinical care and help develop clinical care guidelines. Trial registration: This study protocol including the patient information and consent forms has been approved by medical ethical reviewing committee ('METC Oost-Nederland'; https://www.ccmo.nl/metcs/erkende-metcs/metc-oost-nederland, file number: 2023–16401). It is registered at ClinicalTrials.gov (NCT06132750; study registration date: 2023-10-05; study first passed date: 2023-11-15). [ABSTRACT FROM AUTHOR]

Aedes aegypti, the vector for dengue, chikungunya, yellow fever, and Zika, poses a growing global epidemiological risk. Despite extensive research on Ae. aegypti's life history traits and behavior, critical knowledge gaps persist, particularly in integrating these findings across varied experimental contexts. The plasticity of Ae. aegypti's traits throughout its life cycle allows dynamic responses to environmental changes, yet understanding these variations within heterogeneous study designs remains challenging. A critical aspect often overlooked is the impact of using lab-adapted lines of Ae. aegypti, which may have evolved under laboratory conditions, potentially altering their life history traits and behavioral responses compared to wild populations. Therefore, incorporating field-derived populations in experimental designs is essential to capture the natural variability and adaptability of Ae. aegypti. The relationship between larval growing conditions and adult traits and behavior is significantly influenced by the specific context in which mosquitoes are studied. Laboratory conditions may not replicate the ecological complexities faced by wild populations, leading to discrepancies in observed traits and behavior. These discrepancies highlight the need for ecologically relevant experimental conditions, allowing mosquito traits and behavior to reflect field distributions. One effective approach is semi-field studies involving field-collected mosquitoes housed for fewer generations in the lab under ecologically relevant conditions. This growing trend provides researchers with the desired control over experimental conditions while maintaining the genetic diversity of field populations. By focusing on variations in life history traits and behavioral plasticity within these varied contexts, this review highlights the intricate relationship between larval growing conditions and adult traits and behavior. It underscores the significance of transstadial effects and the necessity of adopting study designs and reporting practices that acknowledge plasticity in adult traits and behavior, considering variations due to larval rearing conditions. Embracing such approaches paves the way for a comprehensive understanding of contextual variations in mosquito life history traits and behavior. This integrated perspective enables the synthesis of research findings across laboratory, semi-field, and field-based investigations, which is crucial for devising targeted intervention strategies tailored to specific ecological contexts to combat the health threat posed by this formidable disease vector effectively. [ABSTRACT FROM AUTHOR]

Aedes aegypti, the vector for dengue, chikungunya, yellow fever, and Zika, poses a growing global epidemiological risk. Despite extensive research on Ae. aegypti's life history traits and behavior, critical knowledge gaps persist, particularly in integrating these findings across varied experimental contexts. The plasticity of Ae. aegypti's traits throughout its life cycle allows dynamic responses to environmental changes, yet understanding these variations within heterogeneous study designs remains challenging. A critical aspect often overlooked is the impact of using lab-adapted lines of Ae. aegypti, which may have evolved under laboratory conditions, potentially altering their life history traits and behavioral responses compared to wild populations. Therefore, incorporating field-derived populations in experimental designs is essential to capture the natural variability and adaptability of Ae. aegypti. The relationship between larval growing conditions and adult traits and behavior is significantly influenced by the specific context in which mosquitoes are studied. Laboratory conditions may not replicate the ecological complexities faced by wild populations, leading to discrepancies in observed traits and behavior. These discrepancies highlight the need for ecologically relevant experimental conditions, allowing mosquito traits and behavior to reflect field distributions. One effective approach is semi-field studies involving field-collected mosquitoes housed for fewer generations in the lab under ecologically relevant conditions. This growing trend provides researchers with the desired control over experimental conditions while maintaining the genetic diversity of field populations. By focusing on variations in life history traits and behavioral plasticity within these varied contexts, this review highlights the intricate relationship between larval growing conditions and adult traits and behavior. It underscores the significance of transstadial effects and the necessity of adopting study designs and reporting practices that acknowledge plasticity in adult traits and behavior, considering variations due to larval rearing conditions. Embracing such approaches paves the way for a comprehensive understanding of contextual variations in mosquito life history traits and behavior. This integrated perspective enables the synthesis of research findings across laboratory, semi-field, and field-based investigations, which is crucial for devising targeted intervention strategies tailored to specific ecological contexts to combat the health threat posed by this formidable disease vector effectively. [ABSTRACT FROM AUTHOR]

Drawing on archival data and oral histories, this paper examines the history of the Eastern Economic Association from its beginnings in 1974 to its 50th anniversary in 2024. It sheds light on the ideological, social, and political motivations behind the EEA's founding, focusing on its commitment to addressing the narrowness of the economics profession and the marginalization of women and underrepresented minorities. It also documents some of the problems that the Eastern Economic Association and the Eastern Economic Journal faced over time and how they have resolved these problems. Based on this history and analysis, the paper contributes to a deeper understanding of the EEA's enduring impact on the field of economics and its continuing relevance in fostering a more inclusive and pluralistic academic community. [ABSTRACT FROM AUTHOR]

The article discusses the evolution of cinema historiography, emphasizing the shift towards new methodologies and theories in studying film history. It highlights the importance of considering cinema as a social event and integrating diverse research methodologies. The emergence of new cinema historians has led to a focus on audience experiences, distribution, and exhibition practices, moving away from traditional film-centric approaches. The article also explores the impact of digital humanities and memory studies on reshaping cinema historiography, offering a more inclusive and comprehensive understanding of cinema culture. [Extracted from the article]

Amphibians have the least studied life histories among vertebrates, although they have unique and the most diverse life histories within this group. We compiled a new dataset on adult body mass and 16 other life history traits of 2069 amphibian species across three orders (1796 frogs, 236 salamanders, 37 caecilians). These traits characterise fecundity, offspring development from egg deposition to metamorphosis and adult life. We established allometric models on traits for all amphibians and each of the three orders to assess a potential scaling of traits to body mass and then checked whether allometric slopes were consistent with two different metabolic scaling exponents. Further, we examined a possible fast‐slow continuum in all amphibians, as well as in each of the two orders frogs and salamanders by applying principal component analysis (PCA) to five traits. Our allometric models indicated a positive scaling to body mass for 11 traits across all amphibians, 12 in frogs, and 10 in salamanders, and for five out of eight traits analysed in caecilians. Allometric slopes on most traits characterising offspring development were not significant. All slopes did not support a three‐quarter metabolic scaling exponent, whereas slopes on age at maturity and maximum longevity were consistent with an amphibian metabolic scaling exponent of 0.88. As in fishes, reptiles, birds, and mammals, the first axes of our PCAs indicated a body mass‐dependent fast‐slow continuum in amphibians. Amphibian species of slow life histories have larger body masses, later sexual maturities and longer lifespans and lay more and larger eggs than species of fast life histories, a pattern also known from reptiles. The second axes indicated a trade‐off between egg size and number. As this trade‐off was nearly independent of body mass, we hypothesise that amphibians have occupied a broad range of ecological niches without evolutionary changes in body mass. [ABSTRACT FROM AUTHOR]

During the 1950s, John K. Fairbank introduced the 'Impact–Response' paradigm for the study of the Christian mission in the non-Western world, focusing on the impact of Western civilization, including Christianity, in China, and the Chinese response. In the 1980s, Joseph Levenson and Paul Cohen proposed their 'Tradition-Modernity' and 'China-Centered' paradigms, respectively, shifting more focus onto the discovery of China's own history. In 2002, Dana Robert adopted the concept of 'globalization' to the study of the Christian mission, yet remained 'imperialistic' and overlooked the consequences of the interplay between globalization and localization. It was in 2012, when Xi Jinping introduced his 'China dream', that Chinese scholars began to think more seriously about its implication and the significance of the 'Sinicization of religion'. Zhuo Xinping, while exploring the concept of the 'Sinicization of Christianity', hinted at a new direction, where "China needs the world as the world needs China, ...in which Christianity would play an important role" (p. 227). Just as the study of Christianity can help one to understand the development of civilization in the Modern West, the paradigm of the 'Sinicization of Christianity' would help provide a better picture of the history of Christianity by seeing it through the interplay between globalization and localization and taking Western Christianity as merely a partial representation of the global Christianity developed in the West. Hence, in this paper, the author attempts to propose it as a new paradigm for the study of the history of Christianity in China today. [ABSTRACT FROM AUTHOR]

Background: Pericardial cysts, though rare and benign, can present with various clinical symptoms depending on their size and location in the body. The detection of these cysts typically relies on imaging studies for a conclusive diagnosis, with surgical removal being the definitive treatment. Case presentation: This case report details the clinical journey of a 32-year-old Iranian woman with a family history of breast and lung cancer, who experienced left-sided chest pain. Utilizing a combination of clinical history review, mammography, echocardiography, and computed tomography, a precise diagnosis of a 10 cm × 3.5 cm pericardial cyst was achieved. The patient underwent median sternotomy for complete cyst excision. Conclusions: While pericardial cysts are often asymptomatic and benign, they can lead to life-threatening complications. Hence, regular follow-up is advised, and in certain instances, minimally invasive interventions or surgery may be necessary. [ABSTRACT FROM AUTHOR]

This essay offers an interpretation of the canonical history of strolling as a non-economic practice, that is, as a practice free of purpose and means. I consider strolling as a state of mind that discloses abundance in a similar way as rationality discloses scarcity. I inquire into the multiple facets of this state of mind by re-reading three phases in its literary and cultural history: the early modern artist-stroller of the nineteenth-century panoramic literature that finds its peak in Charles Baudelaire; the high modern consumer-stroller as described in the inter-war period, notably in the work of Walter Benjamin; and the late modern subversive stroller that is re-discovered in the mid-twentieth century by the Situationist Guy Debord among others. This interpretation both sheds light on the social preconditions of economic rationality as an organizing principle of a market society, as well as the potential to step out of this principle. [ABSTRACT FROM AUTHOR]

The rise of global history has fundamentally reshaped historical scholarship over recent years. Questions about class structures, however, have rarely been specifically addressed by global historians. Scholars of social history, meanwhile, have traditionally studied social stratification within national frameworks. The introduction to this special issue addresses these shortcomings, exploring global social history as a new field of historical inquiry. Interweaving global and social history, it demonstrates that we cannot understand the emergence and transformation of social groups across the modern world - groups such as the aristocracy, the economic bourgeoisie, the educated middle classes, the peasantry, or nomadic groups - without considering how they were influenced by global entanglements. Moreover, it points out that we have to examine globalization as a social process that was shaped by particular social groups. The special issue will connect the study of global connectivity with that of the emergence and evolution of social structures. [ABSTRACT FROM AUTHOR]

Background/Objectives: A family history of Parkinson's disease (PD) is an important risk factor for developing PD. Because only a few studies have investigated the clinical characteristics of PD patients based on family history, this study compared the clinical characteristics of PD patients with and without a family history of PD. Methods: The study involved 356 patients with de novo PD. The data on the patients' PD family histories were obtained from the patients and their caregivers. Motor and non-motor PD symptoms were assessed using the appropriate scales. Results: Out of the 356 PD patients, 26 (7.3%) had a family history of PD. Compared with patients without a family history of PD, those with a family history of PD tended to be younger at diagnosis (67.9 years vs. 62.2 years, respectively; p = 0.009) and exhibited significantly more severe rigidity (p = 0.036). Motor subtype was not different between the PD patients with and without a family history. PD patients with a family history experienced significantly fewer falls/cardiovascular symptoms within the Non-Motor Symptoms Scale domains (p = 0.001) compared to their counterparts, although this was not statistically significant upon adjusting for age (p = 0.119). Conclusions: In de novo PD patients, having a family history of PD is associated with a younger age at diagnosis and more severe rigidity. [ABSTRACT FROM AUTHOR]

The first year in art schools, academies, and departments is a perennial unsolved problem. The experiment we describe here reimagines the entire history and problematics of the foundation year all at once. Our proposal is that art history and studio instruction can be deconstructed and merged, producing a coherent first-year experience. The experiment we describe here is a collaboration between art history and studio art at the School of the Art Institute of Chicago in summer 2021. [ABSTRACT FROM AUTHOR]

The article explores the historical development of intellectual history with a focus on how women's ideas have been represented and studied within the field. Topics discussed include the lack of attention to women's intellectual contributions in early intellectual history reviews, the limited representation of women thinkers in major journals, and the broader historiographical implications of this oversight.

This essay stages an encounter between Michel Foucault and Franz Rosenzweig by juxtaposing their parallel observations on the continuity between history and war. While Foucault analyzes the strategies organizing seventeenth-century historical writing about the Norman conquest of England and the Frankish invasion of Gaul, Rosenzweig opposes the warlike progress of Christian history to the eternal peace of Jewish time. Through this comparison, the essay reevaluates the terms governing well-known debates about Jewish history and Jewish memory. It asks what role the concept of "war" has played in the emergence of modern Jewish historicism and the so-called Jewish return to history. The essay concludes by submitting the Israelite conquest of Canaan as a supplement to Foucault's examples and as a critical index of the bellicose grammar underwriting the representation of Jewish history as a field of struggle. [ABSTRACT FROM AUTHOR]

Historical awareness related to Indonesia is mandatory for all Indonesians, namely awareness that we started from the same historical journey of the nation. This research aims to develop the 'CABASA' application as Sragen cultural heritage-based historical learning media is capable of displaying descriptions, as well as photos of cultural heritage. This Development uses three main steps adopted by Borg and Gall: the preliminary stage, the planning stage, and the testing stage. The trial results of the 'CABASA' product developed are suitable for use in the history learning process. The conclusion is the development method adopted in this research is simplified into three main steps. Preliminary development studies and the final stage are product trials. With the product trial results being very feasible, it can be concluded that 'CABASA' can be used as an interactive learning media based on cultural heritage in the Sragen district, which is following current developments where this learning media is straightforward to use. [ABSTRACT FROM AUTHOR]

Background: In order to recruit and retain Latinx teachers, we must first understand how they choose to enter teaching; are socialized; and the influence of factors such as race, ethnicity, and culture on their beliefs and teaching practices. Purpose: The purpose of this study was to explore the life history of Oscar, a Latino immigrant preservice physical education teacher. Method: Occupational socialization theory and life history methodology guided all the steps of this study. Results: Oscar's life history revealed key narratives that were influential in constructing his socialization toward teaching and coaching. A constant search for belonging was an emerging theme. Conclusion: This life history highlights the significance and value in voicing the experiences and perspectives of our up and coming ethnically diverse educators. Oscar's story adds a diverse lens to the occupational socialization and life history literature, especially from a recruitment and retainment standpoint. [ABSTRACT FROM AUTHOR]

Boltzmann's H-function H(t), often regarded as an analog of time-dependent entropy, holds a venerable place in the history of science. However, accurate numerical evaluation of H(t) for particles other than atoms is rare. To remove this lacuna, we generalize Boltzmann's H-function to a gas of molecules with orientational degrees of freedom and evaluate H(t) from the time-dependent joint probability distribution function f(p, L, t) for linear (p) and angular (L) momenta, evolving from an initial nonequilibrium state, by molecular dynamics simulations. We consider both prolate- and oblate-shaped particles, interacting via the well-known Gay–Berne potential and obtain the relaxation of the generalized molecular H(t) from initial (t = 0) nonequilibrium states. In the long-time limit, the H function saturates to its exact equilibrium value, which is the sum of translational and rotational contributions to the respective entropies. Both the translational and rotational components of H(t) decay nearly exponentially with time; the rotational component is more sensitive to the molecular shape that enters through the aspect ratio. A remarkable rapid decrease in the rotational relaxation time is observed as the spherical limit is approached, in a way tantalizingly reminiscent of Hu–Zwanzig hydrodynamic prediction with the slip boundary condition. In addition, we obtain H(t) analytically by solving the appropriate translational and rotational Fokker–Planck equation and obtain a modest agreement with simulations. We observe a remarkable signature of translation–rotation coupling as a function of molecular shape, captured through a physically meaningful differential term that quantifies the magnitude of translation–rotation coupling. [ABSTRACT FROM AUTHOR]

This research explains the use of the oral history collection of the National Archives of the Republic of Indonesia (ANRI) to optimize historical information as a primary source. Sources of information with this primary category relate to information from historical actors or eyewitnesses and witnesses to an event. Oral history archives are the main content of this research. The method used is descriptive qualitative, focusing on observing the content of oral history information published on websites and various social media platforms affiliated with ANRI. This research aims to analyze the oral history collection owned by ANRI and the historical information content contained in the collection. The results of this paper describe the content of oral history, which has primary information specifications based on the information needs in the archives. This information is helpful to complement information originating from textual sources. Open access to ANRI's oral history collection helps fulfill information needs that primary textual information sources cannot fully meet. [ABSTRACT FROM AUTHOR]

This article delves into the previously underexplored conceptualizations of history articulated in the initiatory homilies of late fourth-century Greek catechists Cyril of Jerusalem and John Chrysostom. Grounded in their interpretation of the (Judeo-)Christian tradition, both authors conceive history as a divine narrative, constituting a coherent “history of salvation”. Metaphorically, their historical understanding can be illustrated as a spatial entity characterized through geometric imagery. A systematic analysis of their catecheses reveals that, fundamentally, both authors maintain a linear perspective on history, emphasizing divine beginning in creation and continuing through the present toward an eschatological consummation. Nonetheless, Cyril introduces more nuanced models, including cyclical depictions, notably a four-staged vision of paradise intertwined with a spiral-like conception of history. Owing seemingly to their primary objective of guiding audiences toward robust engagement with the Christian tradition and ecclesial participation, both authors refrain from addressing themes that might provoke unwarranted speculation. By presenting these insights, this article offers a novel contribution to the scholarship on late fourth-century theology of history, concurrently paving the way for historiographical exploration in modern scholarship of late antique Christian sources. [ABSTRACT FROM AUTHOR]

"Preserving Useful Knowledge: A History of Collections Care at the APS Library" is a book that explores the history of collections care at the American Philosophical Society (APS) Library in Philadelphia. The author, Renée Wolcott, argues for the preservation of historic conservation practices and emphasizes the importance of considering the multilayered histories of collection items and the stewards of those items. The book provides a comprehensive overview of the evolution of conservation as a profession and highlights notable conservators and their contributions throughout history. Wolcott also advocates for improved documentation of conservation treatments to better understand their impact on objects and make informed treatment decisions. This book is valuable for conservators, curators, librarians, and anyone interested in the history of collections care and preservation. [Extracted from the article]

The article "International Law and the Politics of History" by Anne Orford explores the intersection of law and history in the context of international economic law. Orford delves into the debate between lawyers and historians regarding the proper methods of addressing the histories of international law, focusing on the role of historical argument in international legal disputes, particularly in the fields of trade and investment law. The article critiques Quinn Slobodian's work on neoliberalism and economic integration, highlighting the importance of historical narratives in shaping legal arguments. Orford calls for lawyers to responsibly engage with the past to make effective interventions in the present, drawing on the concept of the uncanny to emphasize the hidden histories that underpin legal practice. [Extracted from the article]

This essay reviews three recently published books on the intellectual history of the Italian Renaissance. In his survey of Italian humanism in the "long fifteenth century" (c. 1350–c. 1525) The Intellectual World of the Italian Renaissance, Christopher Celenza argues that the intellectual project of the humanists was centred on questions regarding language, philosophy, and the stance of the intellectual toward institutions. Celenza traces the fortunes and mutations of the humanist project into the modern era in The Italian Renaissance and the Origins of the Humanities, and expresses concern that in today's universities the balance struck by the humanists between "openness" and "boundary-generating habits" unduly favours the latter. Humanism, according to James Hankins's Virtue Politics, was primarily about repairing politics by first reforming the moral character of Italy's ruling elites. The language and literature of Roman and Greek antiquity provided the models for this education in virtue. Hankins believes the humanists' educational and cultural programme offers a salutary corrective to our misplaced, post-Machiavellian trust in legal constraints and constitutional guardrails to regulate contemporary political life. [ABSTRACT FROM AUTHOR]

Skin problems are common, affecting up to one-third of the population during their lifetime, and they are frequently encountered by advanced clinical practitioners (ACPs) in both primary and secondary care settings. Despite the prevalence of dermatological presentations, ACPs often feel unprepared to conduct a thorough dermatological history and examination. This article aims to provide guidance to trainees and qualified ACPs, whether in acute hospital settings or primary care, to perform dermatological assessments and examinations systematically. This is the first article in a two-part series on dermatological assessment. [ABSTRACT FROM AUTHOR]

The evolution of cancer cells parallels species evolution in numerous ways. Variations arise and spread under the pressure of competition between cancer cells. Current investigations of tumor evolution echo earlier debates between biologists. These include the role of non-Darwinian mechanisms, the contribution of neutral evolution, and life history dynamics. The trade-off between proliferation and metastasis is the most well-studied application of life history theory to cancer evolution. This article briefly introduces some parallels between cancer and species evolution, focusing on the life history of evolving tumors. Next, we review evidence from simulation and experimental studies supporting task specialization and trade-offs in cancer. We also cover recent work on inferring tumor tasks from data. We then turn to the implications of multi-tasking and the utility of the theory in explaining critical aspects of tumor heterogeneity. Finally, we discuss some of the criticism and future directions of this research topic. [ABSTRACT FROM AUTHOR]

Copyright of Annals of the Faculty of Arts is the property of Ain Shams University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

"Plunder for Profit: A Socio-environmental History of Tobacco Farming in Southern Rhodesia and Zimbabwe" is a book that explores the complex relationship between tobacco farming and the environment in Zimbabwe. The book discusses how tobacco farming, while being a major source of income for the country, also leads to deforestation, land degradation, air and water pollution, and pesticide poisoning. The author, Elijah Doro, who has personal experience as a tobacco farmer, argues for the need for new agricultural systems that can phase out tobacco in Zimbabwe. The book provides a historical perspective on the socio-environmental impacts of tobacco farming and highlights the need for sustainable alternatives. [Extracted from the article]

This article explores the historical impact of droughts in the early modern Caribbean and their effects on the region's environment and population. The author examines a letter from 1726 written by Colonel John Hart, the Governor of the British colony of the Leeward Islands, which describes the devastating consequences of a prolonged drought in Antigua. The letter raises questions about climate change, water security, and environmental racism, highlighting the need for further research on how colonialism altered the region's climate and affected the lives of African, Indigenous, and European residents. The article emphasizes the importance of understanding the historical context of droughts in order to address present-day challenges of water insecurity and climate change in drought-prone regions worldwide. [Extracted from the article]

The article "Towards an informed democracy: a history of the Queensland Parliamentary Library" traces the establishment and evolution of the Queensland Parliamentary Library since its inception in 1860. Initially catering to a privileged leisure class, the library has transformed over time to meet the needs of Members of Parliament by providing authoritative and unbiased information. The article highlights key figures like Denis O’Donovan, who significantly expanded the collection and introduced innovative cataloging methods. Subsequent librarians like Desmond Ryan and SG Gunthorpe focused on modernizing services and adapting to technological advancements, culminating in the development of an automated retrieval system in 1976. The library's dual role in preserving heritage collections and supporting an informed democracy is emphasized, underscoring its historical significance and ongoing relevance. [Extracted from the article]

Despite its now totemic constitutional status, Magna Carta is not explicitly mentioned in Shakespeare's history play of King John. King John has been interrogated by literary scholars for references to the charter and investigated by historians for potential oversight. Yet, often overlooked are the sporadic references to Magna Carta in nineteenth-century productions of the play. During the nineteenth century, Magna Carta's legal significance waned as clauses were removed from legislation. Its political purchase is well-documented, including its use by the Chartists, and its use in nationalist-based support for wars at the start and end of the century. What is often unheeded in legal scholarship, is the shifting cultural significance of the charter. A performance history of Shakespeare's King John exposes the different treatment of Magna Carta in productions of Shakespeare's play and related theatrical representations of the charter in popular melodrama and pantomimes in the nineteenth century. This paper uses archival material of theatre productions to interrogate the status of Magna Carta through a performance history of Shakespeare's King John in nineteenth-century London. Investigating the representations of Magna Carta in theatre productions offers a complex picture of the charter's place in the history of British constitutionalism. [ABSTRACT FROM AUTHOR]

The Jogja Archives Diorama is a digital diorama which consists of various types of archives, including textual, photo, audiovisual, and oral history, with items sourced from regional, national, and international archives as well as personal collections. This study aims to explore the potential of the Dioram Arsip Jogama as a source of history learning at the high school level with a descriptive qualitative approach. Through field research, the researcher seeks to dig up in-depth information about the relevance of the Jogamar Archive Diogama in the context of historical learning, especially at SMA Negeri 8 Yogyakarta, SMA Prambanan, and SMA Minggir. The research results indicate that (1) the diverse collection at the Digamar Archives is mainly composed of textual and photo archives, and the collection is divided into three categories, including oral history and textual history. (2) The Digamara Archive of Indonesia is relevant to history learning in grades X, XI, and XIII, with the potential to be a learning resource that can support the history learning process. (3) Problem-Based Learning (PBL) is suggested as an effective teaching method to engage students in historical analysis and critical thinking. Future researchers are encouraged to use this study as an a reference for further exploring the utilization of archives as learning resources, especially focusing on expanding the scope of the digamara archive to include more schools and testing different learning models to enhance historical education. [ABSTRACT FROM AUTHOR]

Copyright of Essays in French Literature & Culture is the property of University of Western Australia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)