Search

Manganese-based rare-earth perovskite oxides with excellent dielectric loss and effective magnetic loss have attracted considerable attention as microwave-absorbing materials. Herein, irregular spherical particles of Pr 1-x Ba x MnO 3 (x = 0, 0.02, 0.04, 0.06) were successfully designed and fabricated by a sol–gel combustion method. The Ba2+ doping amount played a dominant role in adjusting the electromagnetic (EM) functions of the PrMnO 3 ceramics. X-ray diffraction and refinement results illustrated that Ba2+ doping had no effect on the main phase of PrMnO 3 , but it caused lattice distortion and led to changes in the lattice constant of the material. The magnetisation curves did not reach saturation, and the materials had low coercivity at room temperature. Fluctuations in the Mn4+/Mn3+ ratio due to oxygen vacancies decreased owing to the addition of Ba2+, as demonstrated by the X-ray photoelectron spectroscopy analysis. It was observed that the absorption of electromagnetic wave (EMW) energy could be effectively controlled by adjusting the Ba2+ content. The Pr 0.98 Ba 0.02 MnO 3 sample exhibited the best EMW absorption ability; the minimum reflection loss (RL min) was -46.45 dB (absorption rate of 99.99%), and the matching thickness was 3.7 mm. The maximum bandwidth of the Pr 0.98 Ba 0.02 MnO 3 sample was 6.16 GHz, while the thickness of the absorbing coating was only 2.5 mm. When d = 5.5 mm, Pr 0.94 Ba 0.06 MnO 3 achieved an RL of -18.97 dB at 5.04 GHz (C band). This shows that Pr 0.94 Ba 0.06 MnO 3 also has good microwave absorption ability in the low-frequency C band, and its RL peak conformed to the nλ/4 cancellation law at a given thickness. The results show that the low-cost sol–gel combustion synthesis process and lightweight, wideband, and strong absorption ability of Pr 1-x Ba x MnO 3 make it a promising candidate for microwave absorbers. [ABSTRACT FROM AUTHOR]

Soft magnetic alloy powder NdNi5-xFex (x = 0.0, 0.1, 0.3, 0.4) was prepared by vacuum arc melting, homogenization annealing and ball milling methods. The reflection loss of NdNi5-xFex powders were discussed based on the structural morphology, measured hysteresis loops and electromagnetic parameters. The lattice distortion and the saturation magnetization of NdNi5-xFex powders increase and the formant of the electromagnetic parameter moves toward the low frequency. The absorption peak of reflection loss also moves toward low frequency. In addition, the Nd–Ni–Fe alloy powder can achieve the best absorption bandwidth, and the minimum reflection loss value of 1.29 GHz and − 29.29 dB, respectively, with the addition of Fe content is 0.1. Add Fe content appropriately, and adjusting the thickness can effectively improve the absorbing performance of the material in c-band, so the powder has a good application prospect in c-band. [ABSTRACT FROM AUTHOR]

Background: Hitherto, a population-based analysis of the cause of death in urban areas of Western China has not been undertaken over an extended period. The aims of this study were to calculate the overall and annual cause-specific mortality rates by age and sex in urban areas of Western China from 2003 to 2012 and to evaluate the quality of the data.Methods: We used Excel software, cause-of-death registrations, and International Classification of Diseases, 10th revision, codes to calculate the overall and yearly cause-specific crude mortality rates by age and sex, the Chinese age-standardized mortality rate, and life expectancies.Results: In the Jiulongpo District from 2003 to 2012, there was an increase in the number of death case reports in the census-registered population, a decrease in the number of omitted deaths, and rise in the crude mortality rate. Except for 2003, the Chinese age-standardized mortality rate was the lowest in 2012 (330.83/100,000) and highest in 2005 (390.08/100,000). Life expectancy increased from 78.36 years in 2005 to 81.67 years in 2012.Conclusions: With the development of its social economy, the Chinese government and public attach greater importance to cause-of-death surveillance. The quality of cause-of-death registrations has gradually increased, crude mortality rates have risen, the Chinese age-standardized mortality rate has fallen, and life expectancies have increased. [ABSTRACT FROM AUTHOR]

H9N2 IAV infection contributed to P. aeruginosa coinfection, causing severe hemorrhagic pneumonia in mink. In this study, the in vitro alveolar macrophage models were developed to investigate the innate immune responses to P. aeruginosa LPS stimulation following H9N2 IAV infection, using MH-S cells. The cytokine levels, apoptosis levels and the viral nucleic acid levels were detected and analyzed. As a result, the levels of IFN-α, IL-1β, TNF-α, and IL-10 in MH-S cells with P. aeruginosa LPS stimulation following H9N2 IAV infection were significantly higher than those in MH-S cells with single H9N2 IAV infection and single LPS stimulation (P < 0.05), exacerbating inflammatory responses. LPS stimulation aggravated the apoptosis of MH-S cells with H9N2 IAV infection. Interestingly, LPS stimulation influences H9N2 IAV replication and indirectly reduced H9N2 IAV replications in in vitro AMs. It implied that LPS should play an important role in the pathogenesis of H9N2 IAV and P. aeruginosa coinfection. • P. aeruginosa LPS stimulation following H9N2 IAV infection exacerbated inflammatory responses. • LPS stimulation aggravated the apoptosis of alveolar macrophages with H9N2 IAV infection. • LPS stimulation indirectly reduced H9N2 IAV replications in alveolar macrophages. [ABSTRACT FROM AUTHOR]

The effect of seed loading and batch trajectory on the growth of crystals with two size coordinates is studied using a simple model for two crystallization systems known to exhibit shape evolution: hen egg white lysozyme and hydroquinone. For moderate seed loading, batch trajectories that lead to a high supersaturation near the beginning of the batch result in a larger nucleated mass and less growth of the seed crystals than other alternatives, while trajectories that keep the supersaturation almost constant give good performance. Increasing seed mass and decreasing seed size also improves performance. Critical seed loading analysis shows that the two-dimensional systems considered in this work behave similarly to one-dimensional crystallization systems considered previously. [ABSTRACT FROM AUTHOR]

Strontium ferrites were prepared by sol-gel method, the phase structure, morphology, and microwave absorbing properties of the samples were studied by X-ray diffraction (XRD), scanning electron microscopy (SEM) and vector network analyzer (VNA). The results show that with increasing sintering temperature, the wave-absorption peak frequency moves towards low-frequency direction and the reflection loss value decreases first, and then increases. At the same sintering temperature (1200 °C) and different holding time (2h, 4h, 6h, 8h), the ferrites have the same Z-type phase structure. With increasing holding time, the absorption peak frequency of the ferrites shift towards low-frequency region, and the minimum reflectivity value decreases first and increases afterwards, and the ferrite holding at 1200 °C for 4 h has the best microwave-absorbing property. [ABSTRACT FROM AUTHOR]

The asymmetric unit of the title compound, C20H32N4O4S, contains one half-molecule; a twofold rotation axis passes through the thiophene ring. Intramolecular N—H⋯O hydrogen bonding results in the formation of a nearly planar six-membered ring, which is oriented at a dihedral angle of 4.60 (3)° with respect to the thiophene ring. In the crystal structure, intermolecular C—H⋯N and C—H⋯O hydrogen bonds link the molecules. [ABSTRACT FROM AUTHOR]

In the title compound, C7H7ClN2O, an intramolecular NH⋯O hydrogen bond helps to establish the conformation. In the crystal structure, intermolecular NH⋯O and OH⋯N hydrogen bonds occur. [ABSTRACT FROM AUTHOR]

In the title compound, C8H6ClN3O, intramolecular CH⋯N hydrogen bonds help to establish the molecular conformation in which the oxadiazole and pyridine rings are coplanar. [ABSTRACT FROM AUTHOR]

We found CRC is sensitive to cuproptosis which also results in IFN-γ-inducible PD-L1 upregulation in tumor cells. A cuproptosis-mediated immunotherapy nanoreactor is constructed for CRC treatment. It not only significantly induces cuproptosis in cancer cells, but also initiates cuproptosis-mediated systemic immune responses, reshapes immunosuppressive TME and prevents immune evasion, further inhibiting both primary and distant tumor growth. [Display omitted] Owing to the deficiency of infiltrating immune cells and the accumulation of immunosuppressive cells in tumor microenvironment (TME), immunotherapy remains enormous challenges in colorectal cancer (CRC). Here, CRC was found to be sensitive to cuproptosis which could further evoke immune responses and mediate immune resistance. Thus, a cuproptosis-mediated immunotherapy nanoreactor (CCJD-FA) was constructed by encapsulating copper-based shell-coated CaO 2 and bromodomain-containing protein 4 inhibitor JQ-1 with DSPE-PEG-FA. Within tumor cells, CCJD-FA was disassembled under GSH environment, and the exposed CaO 2 could generate H 2 O 2 under the acidic condition, which reacted with the released Cu2+ via Fenton-like reaction to produce O 2 for relieving hypoxia and Cu+ for inducing cuproptosis. Furthermore, CCJD-FA could also inhibit intracellular glycolysis and ATP generation, then blocking the Cu+ efflux protein ATP7B. Meanwhile, the IFN-γ-induced PD-L1 expression could be exactly reduced by the BRD4 suppression and oxygen supply. These effects sensitized cancer cells to cuproptosis, further evoking systemic immune responses and reshaping immunosuppressive TME to inhibit tumor growth. [ABSTRACT FROM AUTHOR]

The article focuses on a study related to detection of the phenicol– oxazolidinone–tetracycline resistance gene poxtA in Enterococcus faecium and Enterococcus faecalis. It discusses that wide use of florfenicol and doxycycline in livestock could promote the spread of poxtA and prevalence of the phenicol–oxazolidinone–tetracycline gene poxtA.

The title compound, C12H9N5O3S2, was synthesized via condensation of 1,2,4-oxadiazole chloromethane with 1,3,4-thiadiazolethiol. The benzene and oxadiazole rings are almost coplanar, making a twist angle of only 4.6 (3)°, but the thiadiazole ring deviates from the molecular plane, making a dihedral angle of 87.9 (3)° with the oxadiazole ring. [ABSTRACT FROM AUTHOR]

In the title compound, C14H21NO4, all the non-H atoms, except for one methyl C atom, lie on a crystallographic mirror plane. An N—H...O hydrogen bond helps to consolidate the crystal packing. A short intramolecular C—H...O contact also occurs. [ABSTRACT FROM AUTHOR]

In multicellular eukaryotes, autophagy is a conserved process that delivers cellular components to the vacuole or lysosome for recycling during development and stress responses. Induction of autophagy activates AUTOPHAGY-RELATED PROTEIN 1 (ATG1) and ATG13 to form a protein kinase complex that initiates autophagosome formation. However, the detailed molecular mechanism underlying the regulation of this protein complex in plants remains unclear. Here, we determined that in Arabidopsis thaliana , the regulatory proteins 14-3-3λ and 14-3-3κ redundantly modulate autophagy dynamics by facilitating SEVEN IN ABSENTIA OF ARABIDOPSIS THALIANA (SINAT)-mediated proteolysis of ATG13a and ATG13b. 14-3-3λ and 14-3-3κ directly interacted with SINATs and ATG13a/b in vitro and in vivo. Compared to wild-type (WT), the 14-3-3λ 14-3-3κ double mutant showed increased tolerance to nutrient starvation, delayed leaf senescence, and enhanced starvation-induced autophagic vesicles. Moreover, 14-3-3s were required for SINAT1-mediated ubiquitination and degradation of ATG13a. Consistent with their roles in ATG degradation, the 14-3-3λ 14-3-3κ double mutant accumulated higher levels of ATG1a/b/c and ATG13a/b than the WT upon nutrient deprivation. Furthermore, the specific association of 14-3-3s with phosphorylated ATG13a was crucial for ATG13a stability and formation of the ATG1–ATG13 complex. Thus, our findings demonstrate that 14-3-3λ and 14-3-3κ function as molecular adaptors to regulate autophagy by modulating the homeostasis of phosphorylated ATG13. [ABSTRACT FROM AUTHOR]

In the title compound, C8H10N2O2, which is a derivative of benzonitrile, there are an intramolecular N—H—O hydrogen bond and intermolecular N—H—O and O-H⋯N hydrogen bonds. [ABSTRACT FROM AUTHOR]

In the title compound, C13H12N4OS2, the dihedral angle between the benzene and oxadiazole rings is 4.8 (3)°. The angle between the oxadiazole and thiadiazole rings is 85.6 (3)°. [ABSTRACT FROM AUTHOR]

In the title compound, C9H6Cl2N2O, the dihedral angle between the oxadiazole and benzene ring planes is 12.40 (19)°. Intra- and intermolecular CH⋯N interactions occur. [ABSTRACT FROM AUTHOR]

In the title compound, C13H12N4OS2, the central oxadiazole ring makes dihedral angles of 8.9 (2) and 89.6 (3)° with the benzene and thiadiazole rings, respectively. [ABSTRACT FROM AUTHOR]

In the title compound, C26H26N4O3, a bifurcated intramolecular NH⋯(O,N) hydrogen bond helps to establish the molecular conformation. The dihedral angles between the oxadiazole ring and the adjacent benzene rings are 14.10 (19) and 17.90 (18)° for the central benzene ring and the (dimethylamino)phenyl ring, respectively. [ABSTRACT FROM AUTHOR]

Objectives: To characterize the genetic environment of the carbapenem resistance determinant in Proteus vulgaris of swine origin.Methods: The carbapenem-resistant P. vulgaris strain BC22 was isolated from a faecal swab from a diseased pig with diarrhoea in Sichuan Province of China in 2018. The presence of carbapenemase genes was screened by PCR. WGS and bioinformatics analysis were performed to analyse the genetic environment of the carbapenem resistance determinant.Results: P. vulgaris strain BC22 was found to harbour the carbapenemase gene blaNDM-1. WGS data revealed that blaNDM-1 was located in a truncated ISAba125 composite transposon. The carbapenem resistance gene blaNDM-1 and 20 other resistance genes, including the multiresistance gene cfr and the bifunctional aminoglycoside/quinolone resistance gene aac(6')-lb-cr, were located in a novel SXT/R391 integrative and conjugative element (ICE). This new SXT/R391 ICE of 148.7 kb was chromosomally located, and could be transferred to Escherichia coli.Conclusions: Here, we report a carbapenemase gene, blaNDM-1, integrated into an SXT/R391 ICE. Our study highlights that this SXT/R391 ICE may facilitate the dissemination of clinically important resistance genes such as blaNDM-1, cfr and aac(6')-lb-cr. [ABSTRACT FROM AUTHOR]

Two novel complexes [Fe 2 ( μ -SC 3 H 6 S)(CO) 5 ][Fc(PPh 2 )CHO] ( 3 ) and 5-{[Fe 2 ( μ -SC 3 H 6 S)(CO) 5 ](PPh 2 Fc)}-10, 15, 20-triphenylporphyrin ( 4 ), which contain ferrocene-based ligand to simulate the role of the active site of [FeFe]-hydrogenases (H-Cluster), are synthesized and characterized successfully. A graphene-mediated [FeFe]-hydrogenases biomimetic nanohybrid (TPP-NHCO-GO-[3Fe2S]) 6 is fabricated by linking organic photosensitizer tetraphenylporphyrin (TPP) and complex 3 to graphene oxide (GO) via the covalent bond. The new nanohybrid 6 is characterized by elemental analysis, Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and inductively coupled plasma atomic emission spectrometry (ICP-AES). By comparing the ultraviolet-visible (UV-vis) absorption, fluorescence emission and time-resolved fluorescence, it can be found the efficiency of electron transfer has been obviously improved with the presence of GO, and the efficiency of electron transfer in intramolecular system is higher than that in intermolecular system. These results are also supported by the photo-induced H 2 production experiments with corresponding catalytic systems in water. Besides, the cystine is used as the sacrificial electron donor for light catalytic reaction in aqueous solution, which improves the efficiency of photocatalytic H 2 production compared with the common electron donors, such as ascorbic acid (H 2 A), triethanolamine (TEOA), glucose or Na 2 S 2 O 3 . [ABSTRACT FROM AUTHOR]

Five tolyl-functionalized monophosphine substituted diiron complexes [Fe 2 (CO) 5 (L){ μ -SC 6 H 3 (CH 3 )S}] (L = PPh 3 , 2 ; Ph 2 PCH 2 Ph, 3 ; Ph 2 PCH 2 CH 2 CH 3 , 4 ; Ph 2 P(2-C 5 H 4 N), 5 ; P(4-C 6 H 4 OCH 3 ) 3 , 6 ), which could be regarded as the active site models of [FeFe]-hydrogenases, have been successfully synthesized from parent complex [Fe 2 (CO) 6 { μ -SC 6 H 3 (CH 3 )S}] ( 1 ). The influence of the different phosphine ligands on the reduction potentials of the models has been evaluated by cyclic voltammetry (CV). According to the result of the electrochemical analysis, complexes 1 , 2 and 5 were chosen to carry out the photocatalytic experiments. Meanwhile, tetraphenylporphyrin (TPP) covalently functionalized graphene oxide (GO) nanocomposite (TPP-GO) and cystine were applied as the photosensitizer and the electron-donor respectively in the [FeFe]-hydrogenases bionic photocatalytic system. The result of light-driven hydrogen (H 2 ) evolution in aqueous ethanol solution demonstrated that the efficiency of H 2 production is affected by following factors: the participation of GO or cystine, the covalent functionalization of GO by TPP and the hetero-atom on the phosphine ligand substituent of [FeFe]-hydrogenases models. Ultraviolet-visible (UV–vis) absorption, fluorescence emission and time-resolved fluorescence were used to analyze and compare the efficiency of electron transferring in the process of photocatalytic H 2 production. And a possible mechanism for the light-driven H 2 evolution of the photocatalytic system containing TPP-GO was proposed. [ABSTRACT FROM AUTHOR]

Eight nickel complexes with chelating N -substituted bis(diphenylphosphanyl)amine and 1,2-benzenedithiolate or 3,4-toluenedithiolate, [RN(PPh 2 ) 2 ]Ni(1,2-SC 6 H 4 S) [R = CH(CH 3 ) 2 , 1 ; CH 2 CH(CH 3 ) 2 , 2 ; CH 2 CH 2 CH 2 CH 3 , 3 ; CH 2 Ph, 4 ] and [RN(PPh 2 ) 2 ]Ni[3,4-SC 6 H 3 (CH 3 )S] [R = CH(CH 3 ) 2 , 5 ; CH 2 CH(CH 3 ) 2 , 6 ; CH 2 CH 2 CH 2 CH 3 , 7 ; CH 2 Ph, 8 ], were synthesized and structurally characterized. The measurement of the electrochemical properties revealed that complex 4 can catalyze protons to hydrogen (H 2 ) under weak acidic conditions. Complex 4 can also be used as a molecular catalyst for light-driven H 2 evolution with a proton source, a photosensitizer, and an electron donor. Furthermore, by using tetraphenylporphyrin (TPP) amide-covalently functionalized graphene oxide (GO) nanohybrid (TPP-NH-GO) as a photosensitizer, the efficiency of photocatalytic H 2 production of complex 4 in aqueous ethanol solution had been astonishingly improved over than for the photocatalytic systems without GO. This result suggests that the excellent properties of GO with respect to electron transfer, surface area, adsorptivity, and hydrophilicity may promote the performance of the photocatalytic H 2 production system to a certain extent. [ABSTRACT FROM AUTHOR]

MnAlNi powder was prepared by the process of vacuum levitation melting and high-energy ball milling, The morphology and phase structure of the powder were analyzed by Scanning Electron Microscope(SEM), X-ray diffraction(XRD) and the effect of the Ni content on microwave absorbing properties of MnAl powder was investigated by an vector network analyzer. The addition of Ni, which improved the microwave absorbing properties of MnAl powder but not changed the composition of Al 8 Mn 5 alloy. The minimum reflectivity of (Al 8 Mn 5 ) 0.95 Ni 0.05 powder with a coating thickness ( d ) of 1.8 mm was about −40.8 dB and has better bandwidth effect, the absorbing mechanism of AlMnNi powders on the electromagnetic was related to the electromagnetic loss within the absorbing coatings and the effect of coating thickness on the interference loss of electromagnetic wave. [ABSTRACT FROM AUTHOR]

Abstract: The phase relationships in the Tb–Fe–Cr ternary system at 600°C have been investigated mainly by X-ray diffraction analysis and first-principles density functional theory calculations. The result shows that the isothermal section consists of 9 single-phase regions, 16 two-phase regions and 8 three-phase regions. The compound TbFe12− x Cr x with the ThMn12-type structure is found to have a broad solubility ranging from x =1.4 to 2.6. The XRD patterns and total-energy calculations suggest that Tb2Fe17 crystallizes with the Th2Zn17-type rhombohedral structure under our experiment conditions. The solid solutions in this ternary system are formed by the substitution of Fe by Cr. The maximum solid solubilities of Cr in (αFe), Tb2Fe17, Tb6Fe23, and TbFe2 are about 17, 12.5, 3, and 7at.% Cr, respectively. [Copyright &y& Elsevier]

The title compound, C7H5ClF3NO, was synthesized by the reaction of 2-chloro-3-hydroxypyridine with 2-chloro-1,1,1-trifluoroethane. The pyridine ring and the O and Cl atoms are nearly coplanar, the largest deviation from the mean plane being 0.078 (6) Å. Bioassay indicates that the title compound has a good fungicidal activity. [ABSTRACT FROM AUTHOR]

The title compound, C12H9ClN4OS2, was synthesized via condensation of 5-chloromethyl-3-(4-chlorophenyl)-1,2,4-oxadiazole with 5-mercapto-2-methyl-1,3,4-thiadiazole. The benzene and oxadiazole rings are coplanar due to the extended aromatic system. The angle between this plane and the thiadiazole ring is 82.2 (3)°. [ABSTRACT FROM AUTHOR]

The title compound, C13H12N4O3S3, was synthesized via condensation of 1,2,4-oxadiazole chloromethane with 1,3,4-thiadiazolethiol. There are three rings in the molecule. The benzene and oxadiazole rings are coplanar due to the extended aromatic system. The angle between this plane and the thiadiazole plane is 82.2°. [ABSTRACT FROM AUTHOR]

The title compound, C12H10N4OS2, was synthesized via condensation of 3-phenyl-5-chloromethyl-1,2,4-oxadiazole with 5-mercapto-2-methyl-1,3,4-thiadiazole. The benzene and oxadiazole rings are roughly coplanar, making a twist angle of only 4.6 (3)°, whereas the thiadiazole ring makes a dihedral angle of 87.9 (3)° with the oxadiazole ring. [ABSTRACT FROM AUTHOR]

The title compound, C13H12N4O2S2, was synthesized via condensation of 5-chloromethyl-3-(3-methoxyphenyl)-1,2,4-oxadiazole with (5-methyl-1,3,4-thiadiazol-2-yl)methanethiol. The benzene and oxadiazole rings are coplanar due to the extended aromatic system. The angle between this plane and the thiadiazole ring is 77.8 (3)°. [ABSTRACT FROM AUTHOR]

In the title compound, C14H9BrN2O2, the whole molecule is roughly planar, the largest deviation from the mean plane being 0.159 (6) Åfor the phenol O atom. The occurrence of an intramolecular O—H⋯N hydrogen bond might favour this planar conformation. The packing is governed by weak π-π interactions between the oxadiazole and benzene rings of symmetry-related molecules. [ABSTRACT FROM AUTHOR]

• The RF-DNA clones of MEV-SD1 and MEV-SD7 were infectious. • The entire genomes of MEV-SD1 and MEV-SD7 were 5162 bp and 5113 bp in length, respectively. • The palindromic telomeres of the parvoviruses showed the diversity in length and secondary structures. In this study, the infectious RF-DNA clones of two mink enteritis viruses, MEV-SD1 and MEV-SD7, were constructed, which generated progeny virions and seemed to contain an almost or completely full-length genome. The genomes of MEV-SD1 and MEV-SD7 were 5162 bp and 5113 bp in length, respectively. The genomic organizations of MEV-SD1 and MEV-SD7 were similar to that of the other carnivore parvoviruses. The 3′-UTR of the virion strand of MEV-SD1 and MEV-SD7 were 311 bp and 313 bp in length, respectively, containing a 208 bp palindromic sequence assuming Y-shaped configurations. Interestingly, the difference of the 3′ palindromic sequences between MEV-SD1 and MEV-SD7 resulted in the orientation inversion of the hairpin ears. And the 5′-UTRs of MEV-SD1 and MEV-SD7 were 582 bp and 531 bp, respectively, containing a 198 bp palindromic sequence assuming U-shaped configurations, a triplet mismatch (5′-TAC-3′) in the center of the duplex stem and a triplet mismatch (5′-AGA-3′) forming a small asymmetric bubble. The findings demonstrated that the genomic termini of the carnivore parvoviruses showed the diversity in length, base composition, and predicted secondary structure. [ABSTRACT FROM AUTHOR]

In the molecule of the title compound, C26H25N3O5, the dihedral angles between the oxadiazole ring and the adjacent benzene rings are 3.56 (12) and 5.72 (11)°. Intramolecular N—H...O and C—H...O hydrogen bonds result in the formation of four more five-membered planar rings, which are nearly coplanar with the adjacent rings. [ABSTRACT FROM AUTHOR]