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Subjects with maxillary skeletal classes II and III not only express alterations in the hard and soft maxillofacial tissues, but also in the morphology and dimensions of the upper airway. A small space in the upper airway has been associated with sleep disorders, such as snoring and mainly obstructive sleep apnea/hypopnea syndrome (OSAHS). Consequently, interest has increased due to the influence of orthognathic surgery in the airway space. Although there are studies in the literature that have compared upper airway spaces, most have evaluated the changes using two-dimensional images, mainly lateral skull X-rays. The present study aimed to determine the airway volume in subjects with skeletal classes II and III who underwent bimaxillary orthognathic surgery. 80 CBCT exams from 40 subjects obtained before and 6 months after surgery were used. There were 20 class II and 20 class III subjects. For the volumetric analysis, a 3D rendering of the upper airway was made in previously established segments, and then the airway volume was calculated using the 3D Slicer® software version 4.11 (Slicer, USA). The statistical analysis by t-test of related samples revealed statistically significant volumetric increases in the nasopharynx, laryngopharynx, and total volume in class II patients. However, in class III patients, there were significant increases in the nasopharynx and total volume, while the volume was maintained in the oropharynx and laryngopharynx. [ABSTRACT FROM AUTHOR]

The aim of the present study was to establish the influence of different materials on the process of bone regeneration in post-extraction sockets of ovariectomized (OVX) adult female rats. For this, 40 Sprague Dawley rats were used, divided into an experimental group (OVX) (n=20) and a control group (without ovariectomy) (n=20). All rats in the experimental group underwent bilateral ovariectomy to simulate a state of estrogen deficiency osteoporosis. After 12 weeks post OVX, rats from both groups were divided into 4 subgroups, in which the upper right first molar of each rat was extracted. Subsequently, the therapies performed in the post-extraction sockets were A: (N=5) Unfilled alveolus to be used as a negative control. B: (N=5) Biphasic graft application (HA+BTCP). C: (N=5) PRF application. D: Application of a combination of biphasic graft + PRF. After three weeks, the animals were euthanized, and the samples were obtained for the respective analyses. All animals survived to the end of the study without any postoperative complications. The quantitative results of the interradicular bone area of -the upper second molar showed significant differences between the control group and the OVX group. While no differences were observed in the histological description or in the quantitative analysis of collagen fibers type I and III. It is possible to conclude that the model of osteoporosis induced by estrogen deficiency would modify the bone microarchitecture of the Maxilla. However, new studies are necessary to continue with the study of biomaterials for bone regeneration in models of induced osteoporosis. [ABSTRACT FROM AUTHOR]

This documentary and exploratory work emphasizes a qualitative approach as a preliminary and complementary phase of the quantitative. The study is presented in the application of a case and the use of the Theory of Planned Behavior to identify behavioral, normative and control beliefs that influence the motivation in individuals to share their knowledge in communities of public organizations. For this, data was collected from applied interviews to experts of the Tax Administration in Quito-Ecuador. The data were classified and codified in words, expecting the recognition of 63 beliefs which will allow the construction of a questionnaire in the future that validates the relationships between the variables of the motivation model used. In the documentary review, the strengths of qualitative and quantitative are contrasted, their incompatibility is rejected and the selection of hybrid approaches is encouraged, highlighting the best of each method and exemplifying the use of qualitative methods in the construction of typologies of case narratives and modal narratives as categories in the quantitative analysis. [ABSTRACT FROM AUTHOR]

The aim of the present study was to conduct a histopathological analysis of an animal model in rats, which simulates the characteristics observable in bones of patients with osteoporosis. To this end, 10 female rats (Rattus norvegicus) Sprague Dawley of 12 weeks of development and approximately 200-250 g were used. Of these, 5 underwent bilateral ovariectomy (OVX), whereas the remaining 5 were used as control. After 12 weeks of ovariectomy in the experimental group, the animals were euthanized and the two femurs were collected, which were then sectioned to process their distal portion. All the animals survived at the end of the study without any signs of postoperative complications. In the experimental group (OVX), the histological images showed a decrease in the thickness of the cortical bone, a greater amount of cancellous bone, loss of the continuity of the periosteum and endostium around the bone matrix in addition to a greater amount of adipose tissue in the bone marrow, when compared with the control group. It can therefore be inferred that a histopathological phenotype can be found at 12 weeks postovariectomy that would be consistent with osteoporotic characteristics in adult rats. [ABSTRACT FROM AUTHOR]

The decisions made during the early stages of a design process have a huge impact on a product. Owing to the explosion of preliminary ideas, however, designers easily lose track of important ideas and significant information and end up being buried in a pile of plain words. Failing to locate an idea in the context of idea generation makes it difficult to generate new ideas or take optimized decisions. In this study, the authors propose the term map approach to provide a complete bird's eye view of all ideas, which is a higher-dimension graphical representation that helps in inspiring ideas and making decisions among design team members. A software application named CoStorm is developed. Through the case study of the cash-flattener module, which is a crucial component of an automated teller machine, this method is found to contribute in facilitating the ideation and decision-making progress. [ABSTRACT FROM AUTHOR]

To diagnose obstructive sleep apnea syndrome (OSAS), polysomnography is used, an expensive and extensive study requiring the patient to sleep in a laboratory. OSAS has been associated with features of facial morphology, and a preliminary diagnosis could be made using an artificial intelligence (AI) predictive model. This study aimed to analyze, using a scoping review, the AI-based technological options applied to diagnosing OSAS and the parameters evaluated in such analyses on craniofacial structures. A systematic search of the literature was carried out up to February 2024, and, using inclusion and exclusion criteria, the studies to be analyzed were determined. Titles and abstracts were independently selected by two researchers. Fourteen studies were selected, including a total of 13,293 subjects analyzed. The age of the sample ranged from 18 to 90 years. 9,912 (74.56 %) subjects were male, and 3,381 (25.43 %) were female. The included studies presented a diagnosis of OSAS by polysomnography; seven presented a control group of subjects without OSAS and another group with OSAS. The remaining studies presented OSAS groups in relation to their severity. All studies had a mean accuracy of 80 % in predicting OSAS using variables such as age, gender, measurements, and/or imaging measurements. There are no tests before diagnosis by polysomnography to guide the user in the likely presence of OSAS. In this sense, there are risk factors for developing OSA linked to facial shape, obesity, age, and other conditions, which, together with the advances in AI for diagnosis and guidance in OSAS, could be used for early detection. [ABSTRACT FROM AUTHOR]

The nasolabial region is the central esthetic unit of the face and is considered one of the most important determinants of the facial esthetic. The facial morphometry of soft tissues is a very important tool in facial surgery. Advances have been made recently in the capture and analysis of 3D images, which offer great development potential in the diagnosis and treatment of facial deformities. The aim of this study was to characterize the nasolabial region of patient candidates for orthognathic surgery using 3D facial captures. A study was conducted to characterize the width of the nasal base and the nasolabial angle in adult patients through 3D photographs. 30 subjects were included, taking two 3D photos each, one in a resting position and the other smiling. The three-dimensional capture was done with the 3dMDface System. The measurements were taken with the 3dMD Vultus software. The length of the alar base was an average of 34.3 ± 2.6 mm at rest, and 39.1 ± 2.9 mm smiling. The mean of the nasolabial angle was 104.6 ± 9.6° at rest and 105.4 ± 14.3º smiling. Additionally, the distance of the alar base smiling compared to its distance at rest increased an average of 4.83 mm, whereas the nasolabial angle smiling increased an average of 0.8º compared to at rest. In this study, the nasolabial angle did not present any significant changes so that its assessments in the case of facial modifications can be standard; the width of the nasal base is significantly modified with the smile and thus a more intense study of any type of modification in this area is required. [ABSTRACT FROM AUTHOR]

The aim of this study was to ascertain the distance from the mandibular canal to the lateral, medial and upper zones of the mandibular ramus in order to identify safety margins that reduce the risk of nerve injuries in the process of removing a bone graft. A descriptive study was conducted, analyzing bilaterally 20 CBCT exams from different patients, taking measurements at 4 points in the central, lateral and medial areas of the corresponding mandibular ramus, which was located at a distance of 5 mm between each line, starting at the distal point of the second molar. Forty hemimandibles were included in this study, estimating a vertical distance for the 4 points of analysis, from between 16 and 17 mm, a distance laterally of 5 mm approximately and medially approximately from 3 to 3.9 mm; the lateral zone was significantly larger than the medial zone. It is estimated that the maximum achievement of a bone block from the area posterior to the second molar must be 13 mm deep and 3 mm laterally to minimize the risks of injuries to the inferior alveolar neurovascular bundle. [ABSTRACT FROM AUTHOR]

The energy state of endosteal implants is dependent on the material, manufacturing technique, cleaning procedure, sterilization method, and surgical manipulation. An implant surface carrying a positive charge renders hydrophilic properties, thereby facilitating the absorption of vital plasma proteins crucial for osteogenic interactions. Techniques to control the surface charge involve processes like oxidation, chemical and topographical adjustments as well as the application of nonthermal plasma (NTP) treatment. NTP at atmospheric pressure and at room temperature can induce chemical and/or physical reactions that enhance wettability through surface energy changes. NTP has thus been used to modify the oxide layer of endosteal implants that interface with adjacent tissue cells and proteins. Results have indicated that if applied prior to implantation, NTP strengthens the interaction with surrounding hard tissue structures during the critical phases of early healing, thereby promoting rapid bone formation. Also, during this time period, NTP has been found to result in enhanced biomechanical fixation. As such, the application of NTP may serve as a practical and reliable method to improve healing outcomes. This review aims to provide an in-depth exploration of the parameters to be considered in the application of NTP on endosteal implants. In addition, the short- and long-term effects of NTP on osseointegration are addressed, as well as recent advances in the utilization of NTP in the treatment of periodontal disease. [ABSTRACT FROM AUTHOR]

The maxillary sinus (MS) is described as a pyramid-shaped cavity of the maxilla. Knowledge of its morphology makes it possible to define normality and abnormality so that its three-dimensional analysis can be a valuable preoperative tool during surgery in this anatomical area. The aim of this study is to present a strategy of morphological analysis of the MS using 3D printing acquired through computed cone beam tomography (CBCT) images. A cross-sectional descriptive study was conducted, including 15 subjects (8 women and 7 men). The 3D virtual reconstruction and modeling was done on the MSs bilaterally, and 30 physical models were produced on a 3D printer. The results revealed that the MSs obtained exhibited various morphologies. An individual analysis of each MS allowed the tripod nature of the MS to be defined. We also were able to observe anatomical repairs such as the MS ostium, as well as complex areas affecting important surgical decisions. This method for creating 3D models of MSs provides a new approach to understanding the precise anatomical characteristics in these structures, which cannot be assessed in the same way on a 2D screen. It may be concluded that 3D printouts of the MS are a suitable method of preoperative analysis that can be useful in educating the patient, however, less time-consuming strategies should be explored. [ABSTRACT FROM AUTHOR]

Abstract: The hydraulic self-balance ring is a very well-known kind of passive balancer of widespread use in the home appliances industry. Its conventional design consists of a hollow ring equipped with a number of anti-sloshing baffle boards of mainly straight shape situated inside the cavity. This paper introduces for the first time a hydraulic balance ring with curved baffles or blades. It is found that the forward blade shape is more suited to improve the transient-state response, whereas the backward blade shape remarkably enhances the steady-state response. A classical dynamics model of this novel bladed balance ring design is developed. Experimental data showing good correlation between the model and tests is also presented. [Copyright &y& Elsevier]

Nearly a century ago, the liquid self-balancing device was first introduced by M. LeBlanc for passive balancing of turbine rotors. Although of common use in many types or rotating machines nowadays, little information is available on the unbalance response and stability characteristics of this device. Experimental fluid flow visualization evidences that radial and traverse circulatory waves arise due to the interaction of the fluid backward rotation and the baffle boards within the self-balancer annular cavity. The otherwise destabilizing force induced by trapped fluids in hollow rotors, becomes a stabilizing mechanism when the cavity is equipped with adequate baffle boards. Further experiments using Particle Image Velocimetry (PIV) enable to assess the active fluid mass fraction to be one-third of the total fluid mass. An analytical model is introduced to study the effects of the active fluid mass fraction on a flexible rotor supported by flexible supports excited by bwo different destabilizing mechanisms; rotor internal friction damping and aerodynamic cross-coupling. It is found that the fluid radial and traverse forces contribute to the balancing action and to improve the rotor stability, respectively. [ABSTRACT FROM AUTHOR]

Osseodensification enhances the stability of endosteal implants. However, pre-clinical studies utilizing osseodensification instrumentation do not account for the limited presence of trabeculae seen clinically. This study aimed to evaluate the effect of osseodensification instrumentation on osteotomy healing in scenarios with and without the presence of trabecular bone. A ~10 cm incision was made over the hip of twelve sheep. Trabecular bone was surgically removed from twelve sites (one site/animal; negative control (Neg. Ctrl)) and left intact at twelve sites (one site/animal; experimental group (Exp.)). All osteotomies were created using the osseodensification drilling protocol. Each osteotomy received an endosteal implant and was evaluated after 3 or 12 weeks of healing (n = 6 animals/time). Histology revealed increased woven and lamellar bone surrounding the implants in the Exp. group relative to the Neg. Ctrl group. The Exp. group demonstrated the presence of bone fragments, which acted as nucleating sites, thereby enhancing the bone formation and remodeling processes. Bone-to-implant contact (%BIC) and bone area fractional occupancy (%BAFO) were significantly higher in the Exp. group relative to the Neg. Ctrl group both at 3 weeks (p = 0.009 and p = 0.043) and 12 weeks (p = 0.010 and p = 0.008). Osseodensification instrumentation in the presence of trabecular bone significantly improved osseointegration. However, no negative influences such as necrosis, inflammation, microfractures, or dehiscence were observed in the absence/limited presence of trabeculae. [ABSTRACT FROM AUTHOR]

Bone regeneration remains a significant clinical challenge, often necessitating surgical approaches when healing bone defects and fracture nonunions. Within this context, the modulation of adenosine signaling pathways has emerged as a promising therapeutic option, encouraging osteoblast activation and tempering osteoclast differentiation. A literature review of the PubMed database with relevant keywords was conducted. The search criteria involved in vitro or in vivo models, with clear methodological descriptions. Only studies that included the use of indirect adenosine agonists, looking at the effects of bone regeneration, were considered relevant according to the eligibility criteria. A total of 29 articles were identified which met the inclusion and exclusion criteria, and they were reviewed to highlight the preclinical translation of adenosine agonists. While preclinical studies demonstrate the therapeutic potential of adenosine signaling in bone regeneration, its clinical application remains unrealized, underscoring the need for further clinical trials. To date, only large, preclinical animal models using indirect adenosine agonists have been successful in stimulating bone regeneration. The adenosine receptors (A1, A2A, A2B, and A3) stimulate various pathways, inducing different cellular responses. Specifically, indirect adenosine agonists act to increase the extracellular concentration of adenosine, subsequently agonizing the respective adenosine receptors. The agonism of each receptor is dependent on its expression on the cell surface, the extracellular concentration of adenosine, and its affinity for adenosine. This comprehensive review analyzed the multitude of indirect agonists currently being studied preclinically for bone regeneration, discussing the mechanisms of each agonist, their cellular responses in vitro, and their effects on bone formation in vivo. [ABSTRACT FROM AUTHOR]

Introducción: La reconstrucción ósea, previo o durante la instalación de implantes dentales, es una técnica rutinaria en la rehabilitación dentoalveolar moderna; clásicamente, la reconstrucción con hueso autógeno ha sido utilizado con altos porcentajes de éxito. Esto requiere de un sitio donante para la extracción del injerto. Dentro de los sitios donantes intraorales, la rama mandibular ha sido utilizada con bajos índices de alteraciones neurosensoriales; esta zona anatómica generalmente no presenta consecuencias morfológicas importantes y no se asocia con alteraciones dentarias cuando se realiza el retiro de hueso; las pocas alteraciones neurosensoriales que presenta pueden limitarse conociendo de forma precisa la posición del nervio alveolar inferior; las tomografías computarizadas de haz cónico han permitido avances importantes en este análisis, sin embargo existen limitados estudios en esta área. Objetivo: Conocer la distancia que existe desde el canal mandibular a la zona lateral y a la zona superior de la rama mandibular a fin de identificar márgenes de seguridad que minimicen el riesgo de lesiones nerviosas en el proceso de retiro de un injerto óseo en bloque para ser utilizado en reconstrucciones óseas. Material y método: Se realizó un estudio descriptivo, analizando bilateralmente 20 exámenes CBCT de pacientes distintos, realizando mediciones en 4 puntos de la zona central, lateral y medial de la rama mandibular correspondiente, los cuales fueron ubicados con distancia de 5 mm entre cada línea, hasta completar los 20 mm. Las mediciones fueron realizadas con el software EZ3D2009 (E-WOO Technology Co, Ltd. Korea) La recolección de los datos fue registrada en una planilla Microsoft Office Excel. Para el análisis de los datos se usó el programa estadístico SPSS Statistics for Windows (versión 23.0, IBM) y se realizó un análisis descriptivo de los datos. Resultados: Cuarenta hemimandíbulas fueron incluidas en esta investigación, estimando una distancia vertical, para los 4 puntos de análisis, de entre 16 y 17 mm, una distancia hacia lateral de 5 mm aproximadamente y hacia medial aproximadamente de 3 a 3,9 mm. Conclusiones: Se estima, que la obtención máxima de un bloque óseo desde la zona posterior al segundo molar debe ser con 13 mm de profundidad y 3 mm desde lateral; considerando una extensión antero-posterior de 20 mm. [ABSTRACT FROM AUTHOR]

Platelet-Rich fibrin (PRF) is a three-dimensional (3-D) autogenous biomaterial obtained via simple and rapid centrifugation from the patient’s whole blood samples, without including anti-coagulants, bovine thrombin, additives, or any gelifying agents. At the moment, it is safe to say that in oral and maxillofacial surgery, PRFs (particularly, the pure platelet-rich fibrin or P-PRF and leukocyte and platelet-rich fibrin or L-PRF sub-families) are receiving the most attention, essentially because of their simplicity, cost-effectiveness, and user-friendliness/malleability; they are a fairly new “revolutionary” step in second-generation therapies based on platelet concentration, indeed. Yet, the clinical effectiveness of such surgical adjuvants or regenerative platelet concentrate-based preparations continues to be highly debatable, primarily as a result of preparation protocol variability, limited evidence-based clinical literature, and/or poor understanding of bio-components and clinico-mechanical properties. To provide a practical update on the application of PRFs during oral surgery procedures, this critical review focuses on evidence obtained from human randomized and controlled clinical trials only. The aim is to serve the reader with current information on the clinical potential, limitations, challenges, and prospects of PRFs. Accordingly, reports often associate autologous PRFs with early bone formation and maturation; accelerated soft-tissue healing; and reduced post-surgical edema, pain, and discomfort. An advanced and original tool in regenerative dentistry, PRFs present a strong alternative and presumably cost-effective biomaterial for oro-maxillo-facial tissue (soft and hard) repair and regeneration. Yet, preparation protocols continue to be a source of confusion, thereby requiring revision and standardization. Moreover, to increase the validity, comprehension, and therapeutic potential of the reported findings or observations, a decent analysis of the mechanico-rheological properties, bio-components, and their bioactive function is eagerly needed and awaited; afterwards, the field can progress toward a brand-new era of “super” oro-dental biomaterials and bioscaffolds for use in oral and maxillofacial tissue repair and regeneration, and beyond. [ABSTRACT FROM AUTHOR]

The aim of this research was to analyze the morphology of the nasal septum and inferior nasal concha bone in class III facial deformities prior to orthodontic treatment in orthognathic surgery candidates. 40 subjects were included in this research. The inclusion criteria were an Angle class III, negative overjet and SNA angle less than 80º. Patients with facial asymmetry, facial trauma or who had undergone maxillofacial or ENT procedures were excluded. CBCT images were obtained for all the patients and the nasal septum deviation, morphology of inferior nasal concha bone and ostium of the maxillary sinus were analyzed and related to the complexity of the facial deformity expressed by the ANB angle and dental relations. The measurement was standardized by ICC and the data was analyzed using a chi square test and Spearman’s coefficient with a p value < 0.005 for statistical significance. Nasal septal deviation was observed in 77.5 %. The deviation angle was 13.28º (±4.68º) and the distance from the midline to the most deviated septum was 5.56 mm (±1.8 mm) with no statistical relation to the complexity of the facial deformity. The deviated nasal septum showed inferior nasal concha bone hypertrophy on the concave side of the nasal septum deviation (p=0.049). The open or closed condition of the maxillary sinus ostium was not related to any conditions in the septum or complexity of the facial deformity. Inferior nasal concha bone hypertrophy could be related to nasal septal deviation. The nasal condition in a class III facial deformity could not differ from the general population; careful in orthognathic surgery as to be assume in the Le Fort I Osteotomy and nasal approach related to nasal septum deviation and inferior nasal concha bone. [ABSTRACT FROM AUTHOR]

The temporomandibular joint (TMJ) is a complex structure in the cranio-maxillomandibular region. The pathological changes of the joint cause deficiencies at different levels, making its replacement necessary in some cases. The aim of this article is to analyze the current indications, treatment and criteria, and follow-up using a systematic review and case series. A systematic review was carried out, identifying the indications for the use of a customized TMJ prosthesis and evaluating criteria and validation in the international literature. After review and exclusion, 8 articles were included with a minimum follow-up of 12 months. The age of the subjects was between 18 and 47 years old. In 226 patients, 310 TMJ prostheses were installed, 168 bilaterally and 142 unilaterally. In most of the articles, a good condition in the follow-up was observed, with a reduction in pain and better conditions of mandibular movement and function. TMJ prosthesis and replacement is a protocolized, defined, stable, and predictable procedure. Indications and criteria must be evaluated by specialists and patients related to the pathology involved in TMJ deformity or degeneration. Randomized research with an accurate diagnosis and follow-up is necessary to obtain the best indication for this treatment. [ABSTRACT FROM AUTHOR]

The design process of journal bearings of turbomachines is complex and time-consuming due to the many geometric and physical variables involved. This paper reports on the design of experiments (DOE) and the response surface design of experiments (RSDOE) methods employed on the design of the drive-end and free-end three-lobe journal bearings supporting a centrifugal compressor rotor. The suitability of each technique is discussed. The bearing design variables employed are bearing slenderness ratio, radial clearance, preload, and lubricant inlet temperature. The rotordynamic response variables selected were the critical speed location, the vibrations at critical speed and operating speed for both bearings, and the threshold speed of instability. The use of a nonlinear (quadratic) RSDOE model is justified. An optimization approach combining an SRDOE and rotordynamic finite element modeling is presented. This method leads to arrive to a multivariate model for multi-objective optimization with very few computations. Identification of the dominant design variables and their effects on several response variables allows establishing engineering feasible solutions with focus on manufacturing versus operating conditions tradeoff. [ABSTRACT FROM AUTHOR]

Orthognathic surgery is performed in subjects with some type of skeletal alteration. Maxillomandibular movements have an impact on the airway (AW) and this aspect must be included into surgical planning. The aim of this research is to determine the changes in the AW after orthognathic surgery. A pilot study was conducted including 51 subjects with class II and class III facial deformity; they were included using the ANB angle and the type of dental occlusion. Cone beam computed tomography were performed showing the maximum volume in the airway and the minimum and maximum areas; in addition, the position of the hyoid bone and the angle of the mandibular plane were included to relate it to the morphology of the AW; to define statistical significance, a value of p<0.05 was established, including the student's t-test and the t-test. The results showed that class II subjects significantly increased the volume and maximum and minimum areas of the AW; skeletal class III subjects did not presented significant differences between the pre- and post-surgical stage; the hyoid bone was in an anterior position in both class II and class III cases. It is possible to conclude that AW improves substantially in subjects with facial class II and remains unchanged in subjects with facial class III. [ABSTRACT FROM AUTHOR]

The aim of this research was to analyze the facial class, presence of malocclusion, and the mandibular plane and to relate this to the mandibular condyle position. A cross-sectional study in subjects under analysis for orthognathic surgery was done. The mandibular plane, the gonial angle, and the molar class were included to compare the coronal and sagittal position of the condyle and the joint space observed in the CBCT. The measurements were obtained by the same observer at an interval of two weeks. In addition, the Spearman test was performed to determine the correlation using a p value < 0.05 to observe any significant differences. Eighty-nine male and female subjects (18 to 58 years old, 24.6 ± 10.5) were included. In the coronal section, subjects with CIII had a greater mediolateral distance (MLD, p = 0.0001) and greater vertical distance (SID, p = 0.0001) than subjects with CII. In terms of the skeletal class and the mandibular plane, it was observed that subjects in the CII group had a greater mandibular angle (open angle) (p = 0.04) than the CII group and was related to the anterior position of the condyle. The most anterior condylar position was observed in the CII group (p = 0.03), whereas a posterior condylar position was significant in CIII subjects (p = 0.03). We can conclude that the sagittal position of the TMJ was related to the mandibular plane and the skeletal class showing a higher mandibular angle and most anterior position of the condyle in CII subjects and a lower mandibular angle and most posterior position of the condyle in CIII subjects. The implications for surgical treatment have to be considered. [ABSTRACT FROM AUTHOR]

Aquatic environments are especially susceptible to being contaminated by pesticides used in agricultural fields. Methyl viologen (MV) is an herbicide with high effectiveness for the control of unwanted land plants; however, it also has a high toxicity towards the algae in the aquatic environment. The objective of this work was to describe the effect of MV on photosynthetic metabolism and its relationship with respiration, growth and the content of photosynthetic pigments of Chlorella vulgaris. The cultures of C. vulgaris were exposed for 72 h at different concentrations of methyl viologen. The results show that growth, pigment content and metabolic activity decrease as the concentration of MV increases. Analysis of the photochemical activity indicates that MV produces an inhibition of electron transport between quinone A and quinone B of photosystem II. The inhibition of photosynthetic electron transport is directly related to the reduction of metabolic activity and cell growth. The results found in this research show that methyl viologen can be a toxic pollutant for primary producers in aquatic environments. [Display omitted] •Exposure to methyl viologen (MV) reduce growth in Chlorella vulgaris. •Photosynthetic activity is more sensitive than cellular respiration to methyl viologen. •Exposure to MV significantly reduces the electron flow in PSII, specifically between QA and QB. •Exposure to MV significantly reduces the content of chlorophylls and carotenoids. • Micromolar concentrations of MV can affect the metabolism and growth of C. vulgaris in 72 h. [ABSTRACT FROM AUTHOR]

The objective of this research was to determine the preferred movements in the maxilla and mandible to obtain normality in facial morphology using superimposition techniques in 3D analysis. A descriptive study was carried out to evaluate bimaxillary bone displacement and hyoid bone in subjects facial class II and facial class III undergoing orthognathic surgery. were used as fixed points for superimposition: Nasion (N) - Silla (S) - Porion (Po) and the zygomatic-maxillary suture (Z). These points were superimposed in pre-surgical and postsurgical CBCT and was evaluated to displacement of the anterior nasal spine, Point A, Point B, Chin and the hyoid bone. For the evaluation and comparison of continuous variables before and after orthognathic surgery, was used the Student's t test. For the correlation between the variables, the Spearman test is used, considering a p value <0.05 as a significant difference. 44 subjects between 18 and 40 years old of both sexes were included in this research. A 90% of subjects a was performed a maxillay sagittal movement. The sagittal movement of mandibular advancement was performed in 100% with facial class type II, while 100 % of the subjects with with facial class type III had a mandibular recession. The hyoid bone advanced in 26 of the 27 subjects with facial class type II. It is possible to conclude that there is a tendency for maxillary advancement, independent of facial deformity. [ABSTRACT FROM AUTHOR]

The article presents a case study of a three-year-old boy who was taken to the emergency room for complaints of nausea, vomiting, and generalized seizures. Computed tomography (CT) scan and conventional angiography confirmed the presence of middle cerebral artery (MCA) aneurysm. He underwent microsurgery with tapping and resection of the aneurysm to eliminate mass effect and was discharged in a better condition.

Background: The purpose of the present study was to evaluate the usefulness of the International Association for Trauma Surgery and Intensive Care (IATSIC)/World Health Organization (WHO)'s Guidelines for Essential Trauma Care ( EsTC Guidelines) in providing an internationally applicable and standardized template to assess trauma care capabilities in the South American Region. Methods: Field assessment was conducted in seven provinces (urban and rural, pop. 2,239,509) and 24 facilities (5 large hospitals (LH); 15 small hospitals (SH); 4 basic hospitals (BH)) in Ecuador using EsTC criteria. A total of 260 individual items in Human Resources (HR- availability, clinical knowledge, skills) and physical resources (PR) were evaluated via inspection, review of local statistics, and administrative and staff interviews. EsTC was evaluated on a scale as follows: 0 (absent); 1(inadequate; < 50%); 2 (partly adequate > 50%); 3 (adequate-100%). Results: 210,045 Emergency Department (ED) visits and 61,365 (29%) ED trauma visits were recorded (incidence rate 2,740/100,000 population). Deficits were noted in prehospital trauma care (inadequate coordination, communication), education and training (ATLS < 30%, TNCC 0%), facility based trauma care (poor physical resources [PR] and human resources [HR]), and quality assurance (1/27 hospitals). Conclusions: The IATSIC/WHO EsTC Guidelines provide a simple and useful template to assess trauma care capability in variable facilities and international settings, and they could serve as a valuable tool for trauma system development. Endorsement of EsTC Guidelines by the Panamerican Health Organization and lead trauma societies (the Panamerican Trauma Society) should be considered. [ABSTRACT FROM AUTHOR]