1. Innovation through Tradition: The Current Challenges in Cancer Treatment.
- Author
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Sapio, Luigi and Naviglio, Silvio
- Subjects
- *
CANCER treatment , *LIQUID chromatography-mass spectrometry , *CELL cycle regulation - Abstract
The high versatility of NDDS could also enable the application of future challenges in cancer therapy, such as improving the cascade technology treatments [[13]]. Thanks to their unique chemical structure, aquatic-derived hTopIB inhibitors may overcome drug resistance induced by intense and prolonged treatments of CPT derivatives, representing an alternative choice in cancer management. A completely different matter applies for advanced and metastatic tumors at onset, in which palliative care is typically administrated with the purpose of alleviating symptom burden and spiritual and psychological distress rather than treating cancer [[4]]. Apart from corroborating the antineoplastic feature mediated by Chlorogenic Acid (CGA) [[7]], Salzillo and coworkers recognized this compound as a potential partner in Doxorubicin-based therapy, expressly in human osteosarcoma cells (OS) [[9]]. [Extracted from the article]
- Published
- 2022
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