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A compact, low-profile, and ultra-wideband antenna is always desirable for airborne Unmanned Aerial Vehicles (UAV) applications. In this paper, an ultra-wideband monopole antenna is presented with the benefit of a compact and low-profile design structure. The antenna design enables efficient communication without interfering with the UAV’s other components. The antenna is designed using a slotted-hexagonal-patch fed from a co-planar microstrip feed. The bow-tie-shaped slot along with a few other rectangular-shaped parasitic slots are loaded in the hexagonal patch for bandwidth enhancement. The coplanar feed with top ground offers minimum interference with the UAV structure. The non-conducting bottom plane allows seamless integration without causing any interference to the antenna. An equivalent circuit model (ECM) of the proposed antenna is also developed. The antenna structure is fabricated and the measured results are validated. A good agreement between the measured and simulated results is observed. The antenna covers an ultra-wideband ranging from 3 GHz to 13.5 GHz with a maximum gain of 4.0dBi. The size of the antenna is 0.24λ0 ×0.29λ0 ×0.01λ0. The developed antenna, therefore, demonstrates that it is a strong contender for ultra-wideband UAV-based applications. [ABSTRACT FROM AUTHOR]

Purpose: Purely cystic brain stem epidermoid is a rare diagnosis among all brainstem cystic lesions. Further, it is very rare in pediatric age group.Methods: Here, we are reporting a rare case of completely cystic brain stem epidermoid in a child. The patient presented with clinical features of brain stem involvement. MRI brain was suggestive of cystic brain stem lesion.Results: Patient went through surgical procedure. Final diagnosis of epidermoid cyst was confirmed on histopathological report.Conclusion: With the help of various advanced sequences of MRI like diffusion and ADC, diagnosis of epidermoid cyst can be established at unusual intracranial site also. Surgical resection of epidermoid cyst at brain stem should be attempted judiciously utilizing all modern tools of neurosurgery. [ABSTRACT FROM AUTHOR]

Neurocysticercosis (NCC) is a parasitic infestation of the central nervous system. NCC parasitic infestation can be misdiagnosed as hydatid cyst or intraventricular epidermoid cyst that can cause a diagnostic dilemma. A 23-year-old male patient presented with headache and vomiting for 3-4 days and giddiness for 4-5 days. Magnetic resonance imaging with contrast was suggestive of a rim-enhancing lesion at the level of the foramen of Monro. Endoscopic excision of the lesion was done, and the patient had relief of a headache and vomiting immediately after the procedure. He is being followed up regularly. Intraventricular NCC occluding both foramen of Monro is a rare entity. Complete endoscopic surgical excision followed by appropriate drug therapy should be given to achieve a cure. [ABSTRACT FROM AUTHOR]

The aim of our paper is to present a new class of functions and to define some new contractive mappings in b-metric spaces. We establish some fixed point results for these new contractive mappings in b-metric spaces. Furthermore, we extend our main result in the framework of b-metric-like spaces. Some consequences of main results are also deduced. We present some examples to illustrate and support our results. We provide an application to solve simultaneous linear equations. In addition, we present some open problems. [ABSTRACT FROM AUTHOR]

A 55 year-old male presented with multiple pus-discharging abscesses and sinuses and mutilating scarring on the gluteal region and back prevalent for the last ten years with exacerbations and remissions. Physical examination revealed acromegaly with frontal bossing, prognathism, a barrel chest and acral hypertrophy. Dermatological examination revealed cutis verticis gyrata, thick eyelids, a large triangular nose, a thickened lower lip, macroglossia, widely spaced teeth and widened skin pores with wet and oily skin. Hair was fine and nails were flat and wide. There were multiple inflammatory papules, tender nodules, draining sinuses, and grouped, polyporous comedones as well as multiple and extensive depressed and keloidal scars localized predominantly over the gluteal region with a few scattered lesions over the back. A computed tomography (CT) scan showed widened sella turcica. His basal fasting growth hormone (GH) levels were markedly raised (230 ng/mL; normal 1-5 ng/mL) while the prolactin levels were moderately raised (87 ng/mL; normal 2-5 ng/mL). These findings were consistent with a diagnosis of acromegaly. The patient was put on antibiotics, nonsteroidal antiinflammatory drugs and isotretinoin at a dose of 1 mg/kg/day, which was increased to 1.5 mg/kg/day. Except for an initial mildly beneficial response, the skin lesions were largely resistant to high doses of isotretinoin at the end of four months. [ABSTRACT FROM AUTHOR]

A letter to the editor is presented about the clouston syndrome associated with severe congenital pseudo-ainhum.

In the present article, the notion of α H- ψ H-multivalued contractive type mappings is introduced and some fixed point results in complete metric spaces are studied. These theorems generalize Nadler's (Multivalued contraction mappings, Pac. J. Math., 30, 475–488, 1969) and Suzuki-Kikkawa's (Three fixed point theorems for generalized contractions with constants in complete metric spaces, Nonlinear Anal., 69, 2942–2949, 2008) results that exist in the literature. The effectiveness of the obtained results has been verified with the help of some comparative examples. Moreover, a homotopy result has been presented as an application. [ABSTRACT FROM AUTHOR]

Topical minoxidil is used for treating different hair disorders. Even though it is an effective therapy, many patients show poor compliance due to the cost, side effects, and duration of treatment. Topical minoxidil is the mainstay treatment for androgenetic alopecia (AGA). Recently, low alcohol or alcohol-free topical minoxidil formulation has proven to be an alternative for patients suffering from AGA, including those with poor compliance with other therapies. Thus, the current article provides the positioning of low alcohol or alcohol-free topical minoxidil to manage AGA in Indian clinical practice. [ABSTRACT FROM AUTHOR]

This work focuses on the design, modeling, simulation and parametric analysis of fixed-guided two beam (FG2B) and fixed-guided four beam (FG4B) piezoelectric energy harvester for ambient energy harvesting application. In these configurations, two and four rectangular beams are connected to the square-shaped proof mass at the center of the structure. The parametric analysis is carried out for the evaluation of displacement, von Mises stress, electric potential and total electric energy generated under varying load conditions i.e., from 1 to 5 g (g = 9.8 m / s 2) . From the modal and the static analysis, it can be deduced that the two beams of FG2B and the four beams of FG4B arrangements are capable of generating 930 mV and 945.12 mV and 48.84 pJ and 51 pJ of electric potential and total electric energy at 5 g input acceleration with the resonant frequency of 556.29 Hz and 780.36 Hz, respectively. These configurations can also be implemented as an energy harvester for low frequency applications. [ABSTRACT FROM AUTHOR]

The article presets a study on the efficacy and safety of narrow-band ultraviolet-B (NB UV-B) phototherapy in childhood psoriasis, conducted in Rohtak, India for a period of two years. The study was administered to 20 children, aged 6-14 years, diagnosed with psoriasis covering more than 20 percent of the body surface. The therapy caused efficient depletion of infiltrating T cells from psoriatic plaques, showing faster clearance of lesions, fewer episodes of erythema and longer remission.

Opioid receptor screening of a conopeptide library led to a novel selective κ-opioid agonist peptide (conorphin T). Intensive medicinal chemistry, guided by potency, selectivity, and stability assays generated a pharmacophore model supporting rational design of highly potent and selective κ-opioid receptor (KOR) agonists (conorphins) with exceptional plasma stability. Conorphins are defined by a hydrophobic benzoprolyl moiety, a double arginine sequence, a spacer amino acid followed by a hydrophobic residue and a C-terminal vicinal disulfide moiety. The pharmacophore model was supported by computational docking studies, revealing receptor-ligand interactions similar to KOR agonist dynorphin A (1-8). A conorphin agonist inhibited colonic nociceptors in a mouse tissue model of chronic visceral hypersensitivity, suggesting the potential of KOR agonists for the treatment of chronic abdominal pain. This new conorphine KOR agonist class and pharmacophore model provide opportunities for future rational drug development and probes for exploring the role of the κ-opioid receptor. [ABSTRACT FROM AUTHOR]

Background: Bone grafting is a dynamic phenomenon. It is a surgical procedure that replaces missing bone with material either from patient's own body, or, an artificial, synthetic or natural substitute. A successful bone graft when applied, heals, becomes incorporated, re-vascularises and eventually assumes the form desired. Aims and Objective: The main purpose of this present study was to radiologically assess and compare the regenerative potential of hydroxyapatite with Collagen (G-Graft) and hydroxyapatite (G-Bone) and to evaluate the clinical usefulness of these materials to enhance bone healing in third molar extraction sites through bone formation. Materials and Methods: The study was carried out in the Department of Oral & Maxillofacilal Surgery, patients were divided into three groups. The rationale for assigning the patients to the groups was strictly random: Group I - G-Graft (Hydroxyapatite with Collagen) was used as Bone graft material, Group II - Bone graft material used was G-Bone (Hydroxyapatite), Group III-control group (no grafts was used). Orthopentomogram(OPG) images were taken intra-operatively, just after extraction in the Group III (control), after extraction but before graft placement in Group I & II (study groups) and post-operatively at the end of first month and third month. Bone density of the post-extraction sockets was measured at four random areas through 'densitometric analysis' software in the OPG program (Kodak 8000C Digital Panoramic System, Eastman Kodak Company) and an average value was recorded at each review. Results: The percentage increase in bone density between 1st month & 3rd month was 7.55± 12.43 in Group I (G Graft), 4.41± 5.4859 in Group II (G Bone), while that Group III (control) was found to be -0.82 ± 3.96. The bone density increase was found to be statistically highly significant (p<0.01)) between all groups. Conclusion: The present study concluded that G-Graft has a definite regenerative potential and is better than G-bone and can be used in bony defects to enhance the bone healing without provoking any significant inflammatory process. The study also indicates that defects treated with G-Graft attain more density initially and that G-Graft enhances bone healing in early stage. [ABSTRACT FROM AUTHOR]

Studies in adults show that pretreatment with an optimal emollient may improve transmission of ultraviolet-B. In our study, we evaluated whether the preirradiation use of mineral oil enhanced the efficacy of narrow-band ultraviolet-B phototherapy in childhood psoriasis. Twenty children, aged 5 to 14 years with widespread, symmetrical psoriasis involving >20% body surface area were enrolled in a prospective, single-blind, controlled study. Mineral oil was applied prior to irradiation over one half of the body and the other half was emollient-free control. Narrow-band ultraviolet-B phototherapy was administered to whole body twice a week on nonconsecutive days with initial dose of 50 mJ/cm2 and increment of 10% at each session. Clinical response was evaluated as grades of erythema, scaling and induration, area of involvement and modified psoriasis area severity index score on each side at baseline, 3, 6, 9, and 12 weeks. Two patients dropped out, 18 patients completed the study. Significantly greater improvement (p < 0.05) in scaling, induration, area of involvement, and modified psoriasis area severity index score was seen on the mineral oil pretreated side as early as 3 weeks and was maintained throughout the study. Difference in erythema was noticed later at 6 weeks. The cumulative dose for clearance was significantly lower on the emollient pretreated side. No adverse effects were observed with mineral oil or narrow-band ultraviolet-B phototherapy. We conclude that preirradiation use of mineral oil enhances the therapeutic efficacy of narrow-band ultraviolet-B phototherapy in children with widespread psoriasis. [ABSTRACT FROM AUTHOR]

The article presents a case study of a 20-year old female with visual obscuration, unsteadiness of gait and holocranial headache. Histological examination revealed big thin-walled vascular channels having angulated capillary sized vessels filled with blood, indicative of the occipital bone's cavernocapillary hemangioma. Postoperatively, she developed hemiparesis in the right side having increase cerebellar signs in the right side which had completely resolved at the last follow-up.