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A new hydroxo‐bridged ruthenium (II) complex [{Ru(η6‐p‐cymene)(iPr2P−O)}2(μ‐OH)]Cl (2) has fortuitously been isolated from the reaction between the known ruthenium(II) complex [RuCl2(η6‐p‐cymene)(iPr2P‐OH)] (1) in either CDCl3 or CHCl3 solutions in the presence of excess DBU (1,8‐diazabicyclo(5.4.0)undec‐7‐ene) at room temperature. Complex 2 is only formed under specific conditions as an orange‐colored air and moisture stable binuclear complex. It is formed via the deprotonation of the P−OH unit in [RuCl2(η6‐p‐cymene)(iPr2P‐OH)]. Complex 2 has been fully characterized by spectroscopic and analytical methods. Its structure was determined by single crystal X‐ray diffraction which reveals a boat‐shaped motif containing a bridging hydroxide unit which undergoes hydrogen bonding with a chloride counterion. Complex 2 was utilized as a catalyst for the hydrogenation of CO2 to formic acid salt using molecular hydrogen. The catalytic reactions were performed at 100 °C in THF in the presence of DBU as a base to isolate [DBU+H][OC(O)H] salt as the final product. Using catalyst loadings down to 0.01 mol%, it was possible to hydrogenate gaseous CO2 with TONs up to 9900. [ABSTRACT FROM AUTHOR]

D-Galactosamine (D-GalN) is a well-established hepatotoxic agent, whereas lipopolysaccharide (LPS) is a bacterial endotoxin; and both in a combination induces the liver damage, which is similar to a human hepatic diseases. In this study, we have evaluated the hepatoprotective activity of the Giant or Black Pigweed, Trianthema portulacastrum L. against D-galactosamine in the presence of lipopolysaccharide (LPS/D-GalN) induced hepatotoxicity using Swiss albino mice. LPS/D-GalN treatment elevated the liver marker enzymes. The combined action of LPS/D-GalN decreased the production of antioxidants such as reduced glutathione (GSH), catalase, superoxide dismutase (SOD), glutathione reductase (GR), glutathione peroxidase (GPx), glutathione S-transferase (GST) and increase in the malondialdehyde (MDA) and nitric oxide (NO) formation. Pretreatment with T. portulacastrum (TP) extract showed dose dependently attenuated liver marker enzymes, increased GSH content, upregulated enzymatic activities of antioxidants in liver, decreased MDA and NO formation. The results also revealed that LPS/D-GalN-treatment increased the inflammation as observed through neutrophil infiltrations and increased the formation of sinusoids as evidenced from the histopathological studies of liver tissue and the TP extract pre-treatment mitigated the neutrophil infiltration and sinusoids formation dose dependently. [ABSTRACT FROM AUTHOR]

The common Giant Pigweed or Black Pigweed Trianthema portulacastrum L.is a well-known hepatoprotactant against chemical-induced toxicity. In this study, we evaluated the radioprotective activity of T. portulacastrum stem extract in Swiss albino mice through survival assay and confirmed by histopathology of the liver and jejunum. We observed that at higher concentrations (200 mg/kg body wt.) of extract, the survival of mice was 20% higher. The mechanism of protection was evaluated by endogenous colony-forming assay, bone marrow cell count, membrane integrity, and antioxidant enzymes of the liver. Histopathology of the liver and jejunum revealed that irradiated animals to have suffered loss of normal architecture of the liver in the form of hepatic sinusoid dilation and neutrophil infiltration, and distorted structure of villi in the jejunum of mice was observed. Pre-treatment of mice with extracts of Trianthema portulacastrum (50, 100 and 200 mg/kg body wt.) attenuated the effects of radiation in a dose-dependent manner. Further, the increased spleen colony numbers and augmented number of bone marrow cells in extract pre-treated mice, in comparison with untreated irradiated mice suggest the protective activity of T. portulacastrum. The treated group of mice also showed increased activities of antioxidant enzymes measured in tissue homogenates of the liver as compared to the untreated irradiated controls. Our present study demonstrated dose-dependent radioprotective property of T. portulacastrum against membrane damage. [ABSTRACT FROM AUTHOR]

We report the first example of homogeneously catalyzed hydrogenation of the N=N bond of azo compounds using a complex of an earth‐abundant‐metal. The hydrogenation reaction is catalyzed by a manganese pincer complex, proceeds under mild conditions, and yields amines, which makes this methodology a sustainable alternative route for the conversion of azo compounds. A plausible mechanism involving metal‐ligand cooperation and hydrazine intermediacy is proposed based on mechanistic studies. [ABSTRACT FROM AUTHOR]

In this article, the performance of silicon FinFET is compared with carbon nanotube (CNT-FET) and 2-D field-effect transistors (2D-FETs) for the upcoming node CMOS logic application. Based on the experimental results, a 17-stage ring oscillator (RO) circuit is implemented using the compact models to analyze the stage-delay and energy-delay performances. A tightly positioned 20- and 10-nm channel-length-based CNT-FET enhances ION and also increases the leakage currents significantly. Due to poor electrostatic control and increased gate leakage, the CNT-FET and 2D-FET provide lowered ION and a limited ac performance. Thus, targeting an off-state current, the FinFET delivers more than three times higher drive current, as well as five times better energy-delay performances in comparison to the CNT-FET and 2D-FET. On the other hand, scaled organic FETs are yet far away to compare with FinFET technology. Hence, the silicon-based (3-D) FETs are leading in all the devices (2-D, 1-D, and 0-D) for scaling next-generation CMOS technology. [ABSTRACT FROM AUTHOR]

The performances of FinFET, gate-all-around (GAA) nanowire/nanosheet, and U-shaped FETs (UFETs) are studied targeting the 3-nm node (N3) and beyond CMOS dimensions. To accommodate a contacted gate pitch (CGP) of 32 nm and below, the gate length is scaled down to 14 nm and beyond. While going from 5-nm node (N5) to 3-nm node (N3) dimensions, the GAA-lateral nanosheet (LNS) shows 8% reduction in the effective drain current (Ieff) due to an enormous rise in short channel effects, such as subthreshold slope (SS) and drain-induced barrier lowering (DIBL). On the other hand, 5-nm diameter-based lateral nanowire shows an 80% rise in total current driving capability (Ieff). Therefore, to enable future devices, we explored electrostatics and effective drive current (Ieff) in FinFET, GAA-FET, and UFET architectures at a scaled dimension. The performances of both Si- and SiGe-based transistors are compared using an advanced device simulator, TCAD Sentaurus. [ABSTRACT FROM AUTHOR]

Herein we report the selective hydrogenation of cyclic imides to diols and amines, homogeneously catalyzed for the first time by a complex of an earth-abundant metal, a manganese pincer complex. A plausible catalytic cycle is proposed based on informative mechanistic experiments. [ABSTRACT FROM AUTHOR]

Medicinal plants are the major folk and traditional medicine for the prevention of diseases worldwide. Trianthema portulacastrum L. (family: Aizoaceae), a small perennial weed, found in the America, Africa, India, and other regions of the world, and are extensively used not only as medicine but also as vegetable for its various health benefits. Phytochemical analysis of T. portulacastrum reveals the presence of alkaloids, phytosterols, terpenoids, saponins, flavonoids and phenolic compounds. In vitro and in vivo studies have demonstrated its pharmacological and biological activities. Different parts of T. portulacastrum L. are conventionally being used as analgesic, anti-pyretic, lipid lowering and microbicide agent; and protect liver and kidney from carcinogen, inflammation and oxidant chemicals. [ABSTRACT FROM AUTHOR]

Abstract: We have developed unprecedented methods for the direct transformation of primary alcohols to alkenes in the presence of hydrazine, and for the synthesis of mixed alkenes by the reaction of alcohols with hydrazones. The reactions are catalyzed by a manganese pincer complex and proceed in absence of added base or hydrogen acceptors, liberating dihydrogen, dinitrogen, and water as the only byproducts. The proposed mechanism, based on preparation of proposed intermediates and control experiments, suggests that the transformation occurs through metal–ligand cooperative N−H activation of a hydrazone intermediate. [ABSTRACT FROM AUTHOR]

Abstract: We have developed unprecedented methods for the direct transformation of primary alcohols to alkenes in the presence of hydrazine, and for the synthesis of mixed alkenes by the reaction of alcohols with hydrazones. The reactions are catalyzed by a manganese pincer complex and proceed in absence of added base or hydrogen acceptors, liberating dihydrogen, dinitrogen, and water as the only byproducts. The proposed mechanism, based on preparation of proposed intermediates and control experiments, suggests that the transformation occurs through metal–ligand cooperative N−H activation of a hydrazone intermediate. [ABSTRACT FROM AUTHOR]

Radiation-induced oxidation of membrane lipids and proteins appear to be responsible for damaging the red cell membranes. The membrane integrity of circulating red blood cells (RBCs) is compromised by the deleterious action of γ-radiation in humans. Trianthema portulacastrum L. is an inexpensive, non-toxic herb commonly used in ayurvedic medicine due to its significant pharmacological activities. Methanolic extract of different parts of T. portulacastrum L. contain carbohydrates, polyphenols, flavonoids, alkaloids and terpenoids; whereas saponin is present only in root extract, while cardiac glycosides are absent in root extract. Here, we explored the radio-protective role of leaf, stem, root and whole plant extracts of T. portulacastrum L. against the γ-radiation induced membrane damage of human red blood cells (RBCs). The RBCs on γ-irradiation (4 Gy) exposure showed elevated TBARS level while inhibited ATPase activities in the membrane ghosts. Treatment of RBCs-with different extracts of T. portulacastrum L. at different doses (50 μg/mL, 100 μg/mL, 200 μg/mL) 1h prior to the exposure of γ-radiation significantly mitigated these changes in the RBC membranes due to presence of antioxidants in the extracts. [ABSTRACT FROM AUTHOR]

Abstract: An unprecedented one‐step synthesis of N‐substituted hydrazones by coupling of alcohols with hydrazine is reported. This partial hydrogen‐borrowing reaction is catalyzed by a new manganese pincer complex under mild reaction conditions, thus liberating water and dihydrogen as the only byproducts. Mechanistic insight, based on the observation of intermediates, is provided. [ABSTRACT FROM AUTHOR]

Abstract: An unprecedented one‐step synthesis of N‐substituted hydrazones by coupling of alcohols with hydrazine is reported. This partial hydrogen‐borrowing reaction is catalyzed by a new manganese pincer complex under mild reaction conditions, thus liberating water and dihydrogen as the only byproducts. Mechanistic insight, based on the observation of intermediates, is provided. [ABSTRACT FROM AUTHOR]

Reaction of 2,3-dihydroxy benzaldehyde with 2-({2-amino phenyl}diazenyl)phenol afforded the ligand 3-(2-(2-hydroxyphenyl)diazenyl)-4-alkylphenyliminomethyl)benzene-1,2-diol. Reaction of H2L with VOSO4 . 5H2O gave the oxido-vanadium(IV) complexes [(L)VO], which exhibited a quasi-reversible oxidative cyclic voltammetric response in a V(IV)/V(V) oxidative process. The complexes act as catalysts in the oxidation of organic thioethers and bromination of phenol. Their cytotoxic properties were examined for three cancer cell lines. [ABSTRACT FROM AUTHOR]

A transition metal free, straightforward synthetic method for the preparation of substituted imidazoles is reported herein. Base promoted, deaminative coupling of benzylamines with nitriles results in the one-step synthesis of 2,4,5-trisubstituted imidazoles with liberation of ammonia. This protocol provides a practical strategy for the synthesis of valuable imidazole derivatives from readily available starting materials. [ABSTRACT FROM AUTHOR]

Catalytic α-olefination of nitriles using primary alcohols, via dehydrogenative coupling of alcohols with nitriles, is presented. The reaction is catalyzed by a pincer complex of an earth-abundant metal (manganese), in the absence of any additives, base, or hydrogen acceptor, liberating dihydrogen and water as the only byproducts. [ABSTRACT FROM AUTHOR]

A ruthenium-catalyzed one-pot synthesis of O-dienyl esters through the regio- and stereoselective addition of carboxylic acids to propargylic alcohols, and the atom-transfer radical polymerisation of the products have been developed. The initial addition reaction takes place through the formation of a carbon-oxygen bond followed by dehydration. [ABSTRACT FROM AUTHOR]

The reaction of multidentate ligand, 3-((E)-(2-((E)-4-aryldiazenyl)phenylimino)methyl)benzene-1,2-diol, H 2 L (H 2 L 1 , 1a ; H 2 L 2 , 1b and H 2 L 3 , 1c ) and (E)-2-((2-(aryldiazenyl)phenylamino)methyl)phenol, HA (HA 1 , 3a ; HA 2 , 3b and HA 3 , 3c ) [where H represents the dissociable protons upon complexation, and aryl groups of H 2 L and HA are phenyl for H 2 L 1 and HA 1 , p -methylphenyl for H 2 L 2 and HA 2 , and p -chlorophenyl for H 2 L 3 and HA 3 ], with Na 2 PdCl 4 separately afforded orthometallated complexes [(L)Pd], ( 2a , 2b and 2c) and [(A)PdCl] ( 4a , 4b and 4c) respectively. In the case of [(L)Pd], the deprotonated L 2− ligands bind palladium (II) in a tetradentate (C,N,N,O) fashion whereas in the case of [(A)PdCl], the deprotonated A − ligands bind Pd(II) in tridentate (C,N,N) manner. X-ray structures of [(L 1 )Pd], ( 2a) and [(A 1 )PdCl] ( 4a ) were determined to confirm the molecular structures. Both the complexes 4a and 5a exhibited catalytic activity toward Suzuki and Heck reactions. Conversion of [(A)PdCl] to its oxidized form upon ligand oxidation is reported. [ABSTRACT FROM AUTHOR]

The new tridentate ligand, SMeNHS = 2-(2-methylthiophenyl)benzothiazolidine, prepared in a single step from commercial precursors in excellent yield, undergoes ring-opening on treatment with Fe(OTf)2 in the presence of base affording a trinuclear iron complex, [Fe3(μ2-SMeNS-)4](OTf)2 (1) which is fully characterized by structural and spectroscopic methods. X-ray structural data reveal that 1 contains four SMeNS- ligands meridionally bound to two pseudooctahedral iron centers each bridged by two thiolates to a distorted tetrahedral central iron. The combined spectroscopic (UV-vis, Mössbauer, NMR), magnetic (solution and solid state), and computational (DFT) studies indicate that 1 includes a central, high-spin Fe(II) (S = 2) with two low-spin (S = 0) peripheral Fe(II) centers. Complex 1 reacts with excess PMePh2, CNxylyl (2,6-dimethylphenyl isocyanide), and P(OMe)3 in CH3CN to form diamagnetic, thiolate-bridged, dinuclear Fe(II) complexes {[Fe(μ-SMeNS-)L2]2}(OTf)2 (2-4). These complexes are characterized by elemental analysis; ¹H NMR, IR, UV-vis, and Mössbauer spectroscopy; and single crystal X-ray diffraction. Interestingly, addition of excess P(OMe)3 to complex 1 in CH2Cl2 produces primarily the diamagnetic, mononuclear Fe(II) complex, {Fe(SMeNS-)[P(OMe)3]3}(OTf) (5). [ABSTRACT FROM AUTHOR]

Ruthenium(II) complexes, [Ru(dppe)(PPh3)(CH3CN)2Cl][BPh4] {dppe = diphenylphosphinoethane} (1) and [Ru(dppp)2(CH3CN)Cl][BPh4] (2) {dppp = diphenylphosphinopropane}, are efficient catalysts for vinylation of pyrazoles by alkynes. While the 1-catalyzed reaction is trans-selective, the corresponding 2-catalyzed reaction is cis-selective. The experimental results have been rationalized by density functional theory calculations. [ABSTRACT FROM AUTHOR]

A series of bis-amides decorated with pyridyl and phenyl moieties derived from L-amino acids having an innocent side chain (L-alanine and L-phenyl alanine) were synthesized as potential low-molecular-weight gelators (LMWGs). Both protic and aprotic solvents were found to be gelled by most of the bis-amides with moderate to excellent gelation efficiency (minimum gelator concentration=0.32-4.0wt.% and gel-sol dissociation temperature T(gel)=52-110°C). The gels were characterized by rheology, DSC, SEM, TEM, and temperature-variable 1HNMR measurements. pH-dependent gelation studies revealed that the pyridyl moieties took part in gelation. Structure-property correlation was attempted using single-crystal X-ray and powder X-ray diffraction data. Remarkably, one of the bis-pyridyl bis-amide gelators, namely 3,3-Phe (3-pyridyl bis-amide of L-phenylalanine) displayed outstanding shape-sustaining, load-bearing, and self-healing properties. [ABSTRACT FROM AUTHOR]

Salt formation has been shown as a simple strategy to induce aggregated induced emission or aggregated enhanced emission in primary ammonium salts derived from 9-anthracene carboxylic acid, 1-pyrene carboxylic acid, 3-coumarin carboxylic acid and histamine. All the salts displayed enhanced fluorescence in their solid state compared to that in their solution state. Single crystal structure of the salt of 9-anthracene carboxylic acid i.e., His-anthracene revealed that restricted intramolecular rotation of the fluorphoric moiety (anthracene) was responsible for such radiative pathway leading to enhanced emission. [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR]

The primary ammonium monocarboxylate (PAM) synthon has been exploited to generate a new series of PAM salts from the free amine of L-phenylalanine-3-pyridyl amide, ( S)-2-amino-3-phenyl- N-(pyridine-3-yl)propanamine (designated as ' B'), and various substituted benzoic acids (designated as ' A(R)'; R=4-Me, 4-Cl, 4-Br, 4-NO2, 3-Me, 3-Cl, 3-Br, 3-NO2, 2-Me, 2-Cl, 2-Br, 2-NO2). The 4- and 3-substituted benzoate salts showed moderate-to-excellent gelation ability with a number of polar and apolar solvents. The gels were characterized by DSC, rheology, SEM and TEM, FTIR spectroscopy, etc. Structure-property studies based on single-crystal powder X-ray diffraction (PXRD) and FTIR data provided insights into the role of the PAM synthon in the formation of the gel networks. Interestingly, some of the gels were capable of forming and stabilizing at room temperature without the use of any exogenous reducing agents. [ABSTRACT FROM AUTHOR]

A series of organic salts derivedfrom various dicarboxylic acidsand two α,ω-diamines, namely, 1,3-diaminopropane and 1,4-diaminobutane,were prepared and characterized by various physicochemical techniques,including single-crystal X-ray diffraction, with the aim of extendingthe well-studied 2D primary ammonium dicarboxylate (PAD) supramolecularsynthon in the context of supramolecular gelation. Single crystalstructures of 9 out of 14 diprimary ammonium dicarboxylate (DPAD) salts were determined. The results showed that noneof the salts displayed the expected 2D DPADsynthon;instead, all of them self-assembled into a 3D hydrogen-bonded network.Consequently, only two salts, namely, B3FAand B4SA, appeared to show gelation behavior producing weakgelsa finding that corroborated well with the current understandingof gelation. [ABSTRACT FROM AUTHOR]

A series of bis-amides derived from L-(+)-tartaric acid was synthesized as potential low-molecular-weight gelators. Out of 14 bis-amides synthesized, 13 displayed organo-, hydro-, and ambidextrous gelation behavior. The gels were characterized by methods including circular dichroism, differential scanning calorimetry, optical and electron microscopy, and rheology. One of the gels derived from di-3-pyridyltartaramide ( D-3-PyTA) displayed intriguing nanotubular morphology of the gel network, which was exploited as a template to generate highly aligned 1D silica fibers. The gelator D-3-PyTA was also exploited to generate metallogels by treatment with various CuII/ZnII salts under suitable conditions. A structure-property correlation on the basis of single-crystal and powder X-ray diffraction data was attempted to gain insight into the structures of the gel networks in both organo- and metallogels. Such study led to the determination of the gel-network structure of the CuII coordination-polymer-based metallogel, which displayed a 2D sheet architecture made of a chloride-bridged double helix that resembled a 5-c net SnS topology. [ABSTRACT FROM AUTHOR]

Abstract: The compound, [Ru(dppe)2(CH3CN)Cl][BPh4] (1) has been synthesized from the precursor complex, [(PPh3)2Ru(CH3CN)3Cl][BPh4]. The complex has been structurally characterized. This complex has been found to be an efficient catalyst for the anti-Markovnikov addition of carboxylic acids to alkynes. [Copyright &y& Elsevier]

The supramolecular synthon approach has been employed to synthesize noncovalently a series of low molecular mass organic gelators (LMOGs) derived from benzylammonium salts of variously substituted benzoic acids. The majority of the salts (75%) prepared showed interesting gelation properties. Instant gelation of an organic fluid, namely methyl salicylate, was achieved at room temperature by using most of the gelator salts by in situ synthesis of the gelators. Table top rheology and scanning electron microscopy (SEM) were used to characterize the gels. Single crystal X-ray diffraction studies revealed the presence of both 1D and 2D supramolecular synthons. X-ray powder diffraction (XRPD) studies indicated the presence of various crystalline phases in the fibers of the xerogels. By using these data, a structure-property correlation has been attempted and the working hypothesis for designing the gelator has been reinforced. [ABSTRACT FROM AUTHOR]

In the above article , there was a typo in tcolor. The units for current density should be “J[A* cm−2].” The corrected figure is presented here. [ABSTRACT FROM AUTHOR]

In the present study, one mononuclear Cu(II) [CuL(SCN)] (1) and one mononuclear Co(II) [CoLN 3 ] (2) complexes, with a Schiff base ligand (HL) formed by condensation of 2-picolylamine and salicylaldehyde, have been successfully developed and structurally characterized. The square planer geometry of both complexes is fulfilled by the coordination of one deprotonated ligand and one ancillary ligand SCN−(1) or N 3 −(2) to the metal centre. Binding affinities of both complexes with deoxyribonucleic acid (DNA) and human serum albumin (HSA) are investigated using several biophysical and spectroscopic techniques. High values of the macromolecule-complex binding constants and other results confirm the effectiveness of both complexes towards binding with DNA and HSA. The determined values of the thermodynamic parameters support spontaneous interactions of both complexes with HSA, while fluorescence displacement and DNA melting studies establish groove-binding interactions with DNA for both complexes 1 and 2. The molecular modelling study validates the experimental findings. Both complexes are subjected to an MTT test establishing the anticancer property of complex 1 with lower risk to normal cells, confirmed by the IC50 values of the complex for HeLa cancer cells and HEK normal cells. Finally, a nuclear staining analysis reveals that the complexes have caused apoptotic cell death. Exploration of two newly synthesized Cu(II) and Co(II) molecular complexes with isothiocyanate and azide ancillary moiety respectively towards DNA/HSA binding and anticancer activity. [Display omitted] [ABSTRACT FROM AUTHOR]

Highlights: A novel optoelectronic synapse compatible with existing chip technology is demonstrated. This device excels in mimicking memory and learning functions using light, making it ideal for future neuromorphic computing in biomedicine. Our design surpasses previous models with its ability to switch between short-term and long-term memory states using light pulses. Experiments on real-world biomedical data (electroencephalogram, electromyography, electrocardiogram) showed significant improvement in classification accuracy. This highlights the device's potential for advanced physiological signal processing and wearable health monitoring systems. The emergence of the Internet-of-Things is anticipated to create a vast market for what are known as smart edge devices, opening numerous opportunities across countless domains, including personalized healthcare and advanced robotics. Leveraging 3D integration, edge devices can achieve unprecedented miniaturization while simultaneously boosting processing power and minimizing energy consumption. Here, we demonstrate a back-end-of-line compatible optoelectronic synapse with a transfer learning method on health care applications, including electroencephalogram (EEG)-based seizure prediction, electromyography (EMG)-based gesture recognition, and electrocardiogram (ECG)-based arrhythmia detection. With experiments on three biomedical datasets, we observe the classification accuracy improvement for the pretrained model with 2.93% on EEG, 4.90% on ECG, and 7.92% on EMG, respectively. The optical programming property of the device enables an ultra-low power (2.8 × 10−13 J) fine-tuning process and offers solutions for patient-specific issues in edge computing scenarios. Moreover, the device exhibits impressive light-sensitive characteristics that enable a range of light-triggered synaptic functions, making it promising for neuromorphic vision application. To display the benefits of these intricate synaptic properties, a 5 × 5 optoelectronic synapse array is developed, effectively simulating human visual perception and memory functions. The proposed flexible optoelectronic synapse holds immense potential for advancing the fields of neuromorphic physiological signal processing and artificial visual systems in wearable applications. [ABSTRACT FROM AUTHOR]

The present study highlights the development, identification, and solvent-regulated chemosensing property of a Schiff base chemosensor (E)-2-(2-((5-chloro-2-hydroxybenzylidene)amino)propyl)-3′,6′-bis(diethylamino)spiro[isoindoline-1,9′-xanthen]-3-one (RBAS). The Schiff base RBAS is developed by the simple condensation of 5-chloro salicylaldehyde and rhodamine-1,2 diamino propane derivative (RBAP). Interestingly this probe can optically as well as fluorometrically exhibit pH sensor activity and the spirolactam ring opening and the conversion from enol to keto form in lower and higher pH regions respectively are the main key factors to show pH sensor activity. Several spectroscopic, Dynamic Light Scattering (DLS), and scanning electron microscopy (SEM) studies confirm the AIE active property of the probe in 2:8 DMSO-water and ethanol-water mediums where the probe exhibits strong luminescence properties. Interestingly in ethanol-water and DMSO-water medium, it can detect Hg(II) via turn-on and off fluorescence respectively. Actually, in different solvent mediums, the presence of Hg(II) plays a crucial role in the spirolactam ring opening and closing of the developed probe. Simultaneously in an ethanol-water medium, it can detect picric acid by turning off fluorescence. By using mass and NMR spectrum analysis, the 1:1 stoichiometric addition of the probe and target analytes has been verified and the density functional theory (DFT) study is implemented in optimizing the probe-analyte structure. The live cell imaging study gives the approval of the biosensing ability of the probe. Impressively the probe can be successfully used to detect Hg(II) in real soil samples. [Display omitted] • Development and spectroscopic identification of a novel rhodamine-based chemosensor (RBAS). • RBAS can be effectively used as pH sensor and spirolactam ring closing or opening controls the pH sensors performance. • DLS, SEM, UV and fluorescence probes the AIE effect of RBAS in two different mediums. [ABSTRACT FROM AUTHOR]

The novel mononuclear Cd(II) metalloreceptor Cd[LH2I2] (complex 1), derived by the reaction of the Schiff base ligand 6,6′-(1E,1′E)(ethane-1,2 diylbis(azaneylidene))bis(methaneylylidene)bis(2-ethoxyphenol) (H2L) and CdI2, was successfully used to detect Zn(II) and Mg(II) in semi-aqueous and aqueous media, respectively, among several competitive cations. The single crystal data analysis revealed that the asymmetric unit of complex 1 consists of one ligand, H2L, and two I-ions, compensating the +2 oxidation state of Cd. The optically monitored sensing of Zn(II) and Mg(II) by complex 1 was further assessed by utilizing UV and fluorescence spectroscopic techniques. The remarkable enhancement of the fluorescence intensity of complex 1-Zn(II) and complex 1-Mg(II) in the presence of CH3COO− and SO4= indicated that a heteronuclear bridging complex could be obtained if two separate reactions of complex 1 with (CH3COO)2Zn and MgSO4 could be carried out. Interestingly, two different single crystals of Cd–Zn (complex 2) and Cd–Mg (complex 3) were obtained after conducting two separate reactions of complex 1 with Zn(II) and Mg(II). Single crystal data analysis showed that complex 2 is an octanuclear Zn(II)/Cd(II) complex with the presence of acetate and an hydroxy group, and both metal centers are in the +2 oxidation state. The IR and NMR spectra results confirmed the formation of complexes 2 and 3. The SPX and EDX studies confirmed the presence of Zn(II) and Mg(II) in complex 2 and complex 3, respectively. The limit of detection for sensing of both was measured in the nanomolar range. Although it is well-known that mononuclear Cd complexes are effective Schottky devices, there have been few reports of investigation of heteronuclear Cd(II) complexes as candidates for effective Schottky devices, or determination of the values of device performance, conductivity, and device parameters with heteronuclear Cd complexes 2 and 3. Surprisingly, all the results indicated that a potential Schottky device could be produced due to the efficacy of complex 2 with respect to complex 3. The effectiveness of the device would be satisfactory because of the lower band gap value and the presence of weak intramolecular π–π stacking interactions in complex 2. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to an article on ruthenium catalyzed alkyne homocoupling and tandem alkyne-azide cycloaddition by U.K. Das and others, published in the "RSC Advances" in 2014.

A reversible fluorescent colorimetric chemosensor L based on a novel mono Schiff base of malononitrile for detection of bicarbonate ion has been established. It demonstrates an excellent selectivity and sensitivity towards bicarbonate ion by change in both colour, absorption and fluorescence intensity. L provides rapid response time and it may be useful as a valuable practical sensor for environmental analyses of bicarbonate ion. [Display omitted] • A reversible fluorescent colorimetric chemosensor L based on a novel mono Schiff base of malononitrile has been established. • L can selectively detect bicarbonate ion with LOD 1.6x10-6M. • L is useful as a valuable practical sensor for environmental analyses of bicarbonate ion. A reversible fluorescent colorimetric chemosensor for fast detection of bicarbonate ion has been established based on a novel mono Schiff base of malononitrile. The chemosensor L is easy to synthesize, eco-friendly and cost effective. It demonstrates an excellent selectivity and sensitivity towards bicarbonate ion by change in both color, absorption and fluorescence intensity. The anion recognition occurs indirectly through coordination of counter metal ion to the Schiff-base ligand. The sensitivity of for bicarbonate ion is much lower than WHO recommended value. L provides rapid response time and it may be useful as a valuable practical sensor for environmental analyses of bicarbonate ion. [ABSTRACT FROM AUTHOR]

An unprecedented nanofabrication of functionalized Pt-NPs under mild conditions was accomplished through oxidative insertion of PtBr2 into the O-C bond of ArCH(OMe)2. TEM and SEM imaging, EELS, XPS, and ESI-MS analyses found the NPs possessing the molecular formula Br2(MeO)PtIVCH(OMe)Ph and low-dimensional spherical morphology. Ketone and amide functionality-bearing electrophilic cyclopropanes underwent ring-opening cyclization. Size-dependent catalytic activity of the NPs was investigated using stabilizers and newly introduced PhCH(OMe)2 during the synthesis of 2-pyrrolines. The organometallic-NPs were effective for cyclopropane ring-expansion using propargyl amine to 1-pyrrolines with depropargylation. Interestingly, the diverse catalytic activity of the Pt-NPs was effective for sp³C-H activated dual cyclization for the direct synthesis of fused-pyrrolo[3,2-c]pyridones. The possible reaction pathway was investigated by 3D-mid-IR-ATR, control experiments, and ESI-MS analyses. The NPs were superior in terms of simple preparation, low catalyst loading, ease of recovery, recycling, diverse catalytic activity, and outstanding ability for the general synthesis of pyrroline analogues. [ABSTRACT FROM AUTHOR]

The current study shows that Schiff base HL, (Z)-2,4-dibromo-6-(((piperidin-2-ylmethyl)imino)methyl)phenol, can be used successfully as a selective chemosensor for Zn(II) and Ni(II) among several competing cations in purely aqueous and semi-aqueous media. Under UV light in methanol–water (9 : 1) HEPES buffer, the receptor gives its response by changing its color to cyan color in the presence of Zn(II) and to bluish cyan color in the presence of Ni(II). Surprisingly, the chemosensor can only reliably identify Zn(II) in a hundred percent aqueous medium by changing its color to light yellow. UV and fluorescence studies in both aqueous and semi-aqueous media are used to further investigate this Zn(II) and Ni(II) recognition phenomenon. The high values of the host–guest binding constants, obtained by electronic and fluorescence titration, ensure that a strong bond exists between HL and Ni(II)/Zn(II). As anticipated, two highly luminescent mononuclear, crystalline compounds, complexes 1 and 2, have been developed by a separate reaction of HL and Zn(II)/Ni(II), and the high luminous properties are due to the occurrence of Chelation Enhanced Fluorescence (CHEF). According to the single crystal structure, the asymmetric units of both complexes consist of two deprotonated chemosensor units and one Zn(II)/Ni(II), leading to the formation of an octahedral complex. For Ni(II) and Zn(II) sensing, the predicted LOD is in the nanomolar range. Both complexes 1 and 2 are fluorescence active and studies to check their ATP detection ability, but intriguingly, only complex 2 is capable of detecting ATP in a fully aqueous solution. Finally, the live cell imaging study validates the two sensors' biosensing functionality. [ABSTRACT FROM AUTHOR]

4-Dimethylaminopyridine (DMAP) in water medium is exploited for construction of an intermolecular assembly of acetyl/benzoyl acetanilides and alkynes for a new [2 + 2 + 2] and [3 + 2] cascade dual annulation. DMAP is expected to act as a promoter for dual annulation and carrier to transport in situ generated water and alcohol from the lipophilic nanoreactors to the water surroundings leading to the first rapid synthesis of fully substituted phthalimide analogues. Insights into the rapid reaction are illustrated in our controlled experiments, dynamic light scattering (DLS) and UV–vis study. [ABSTRACT FROM AUTHOR]

[Display omitted] • Developments of one mononuclear Ni(II) (1) and dinuclear Ni(III) (2) complexes from N, N, O and N, N, O, O donor Schiff base ligand respectively. • Complex 2 shows comparatively better catecholase-like activity than Complex 1. • complex 2 exhibits better DNA and protein binding potentiality, confirmed by implementing several biophysical studies. • Molecular docking results validate the experimental findings. The successful use of metal complexes in enzyme catalysis and biomedical applications boosts researchers to develop more and more metal-based compounds to inspect their said applications. In the present work one novel mononuclear Ni(II) [Ni(L1) 2 ] (1) and one di nuclear Ni(III) complexes [Ni(L2) 2 (N 3) 2 ] (2) have been developed by utilizing N 2 O donor Schiff base ligand HL1 and N 2 O 2 donor Schiff base ligand H 2 L2 respectively. The single crystal data analysis reveals that in complex 1 two deprotonated ligands coordinate to the Ni(II) forming a distorted octahedral geometry. The asymmetric unit of complex 2 comprises one deprotonated ligand (both the protons of phenolic –OH group were deprotonated), one azide anion, and one Ni(III). Two Ni(III) centers are connected via phenoxide bridging. Followed by the structural analysis the UV spectroscopic study is performed to understand the catecholase-like activity of the developed complexes by using 3,5-di-tert butyl catechol (3,5-DTBC). The calculated turnover numbers (K cat) for both complexes disclose the fact that complex 2 is more susceptible to this catalytic process than 1. During the catalysis process, the production of Ni(II) in the case of complex 2 is favorable and this is the main factor to show its higher susceptibility towards the catalytic process. The biomedical applicability in terms of anticancer and antibacterial of complexes 1 and 2 is assessed by evaluating their interaction ability with DNA and HSA with the help of several spectroscopic approaches. The remarkably high complex-macromolecules binding constant values, obtained from electronic titration approve the binding efficacy of the target complexes (order ∼ 105). But if a tiny comparison is done then it is seen that complex 2 shows better DNA and HSA binding efficacy. The theoretical approach using molecular docking study fully validates the experimental findings. [ABSTRACT FROM AUTHOR]

Using two different metalloligands [NiLA] and [NiLB], developed using two different N2O2 donor Schiff bases, H2LA 6,6′-((1E,1′E)-((2,2-dimethylpropane-1,3-diyl)bis(azaneylylidene))bis(2-methoxyphenol) and H2LB 6,6′-((1E,1′E)-((2,2 (2-ethoxyphenol), two new tetra- and trinuclear heterometallic complexes, [(NiLA)2(CH3COO)2(SCN)2(Co)2] (complex 1) and [(NiLB)2(SCN)2Mn] (complex 2), have been synthesized. The two newly formed complexes have primarily been characterized using several spectroscopic techniques. According to the single-crystal structural study, the metalloligand portion is shared by both crystals. Complex 1 is a tetranuclear complex where Ni(II) is connected to Co(II) via acetate and phenoxide bridging, whereas complex 2 is a trinuclear complex where each Ni(II) center is coordinated to Mn(II) via phenoxide bridging only. It is interesting to note that the thiocyanate moiety in complex 1 is linked to Co(II), whereas in complex 2, it is linked to Ni(II) as a secondary anionic residue. Following structural analysis, both complexes were exposed to catecholase-like activity to test their ability to aerially oxidize 3,5-di-tert-butylcatechol. The calculated turnover numbers (Kcat) 355 h−1 and 286 h−1 for complexes 1 and 2, respectively, unveiled that complex 1 is more susceptible to this catalytic process. The generation of Ni(I) in complex 1 is more favorable than the formation of Mn(I) in complex 2 during catalysis and this is the factor responsible for the higher susceptibility of complex 1 towards the catalytic process. To determine whether both the studied complexes can function as effective Schottky devices, the band gap values for complexes 1 and 2 were used to calculate the diode parameters. The results show that complex 1 will function as a better Schottky device than the complex 2. [ABSTRACT FROM AUTHOR]

A new mononuclear Fe3+ metalloligand MC1 [FeLN3(H2O)], developed by using the N2O2 donor Schiff base ligand H2L, has been successfully used to detect and remove Hg2+ and Cd2+ from several transition metal ions with the formation of two unusual hetero metallic μ-oxo Fe3+–Hg2+/Cd2+ clusters, [(Fe23+)(μ-O)L2Cl4(Hg22+)] (MC2) and [(Fe23+)(μ-O)L2I4Cd22+] (MC3) [(where H2L is 6, 6′-(1E, 1′E) (ethane-1, 2 diylbis(azaneylidene))bis(methaneylylidene))bis(2-ethoxyphenol)]. All three complexes were identified by X-ray single-crystal data analysis along with a range of spectral studies. In MC1, the Fe3+ is coordinated with deprotonated H2L, one water molecule, and one azide ion as a secondary anionic residue, forming an octahedral geometry. Interestingly, MC2 and MC3 are isostructural, where each asymmetric unit contains deprotonated H2L, one Fe3+ and Hg2+/Cd2+ metal center, two Cl−/I− and two Fe3+ centers are connected by a μ-O bridge to form tetranuclear complexes. As the band gap energy values of MC1, MC2, and MC3 (3.07 eV, 2.69 eV, and 2.55 eV, respectively) are in the visible region so all the three complexes are exposed to investigate their potentiality to be effective Schottky devices and at the same time a thorough inspection has been carried out to check their catalytic behaviour in aqueous medium in terms of methylene blue (MEB) dye degradation under visible light irradiation. A thorough inspection reveals the better MB dye degradation potentiality of MC3 in comparison to MC2 in the presence of H2O2. At the same time, the investigation of the device performances, conductivity, and device parameters disclose more effectiveness of MC3 in comparison to MC2 in a better Schottky device. The effectiveness of MC3 in both applications may be attributed to its lower band gap value. [ABSTRACT FROM AUTHOR]

This document is a correction notice for an article titled "Highly Efficient Back-End-of-Line Compatible Flexible Si-Based Optical Memristive Crossbar Array for Edge Neuromorphic Physiological Signal Processing and Bionic Machine Vision" published in Nano-Micro Letters. The authors of the article discovered a mistake in the Supplementary file, specifically in figures S11 and S12, where they mistakenly used the same sub-figures. The original article has been corrected. The publisher, Springer Nature, remains neutral regarding jurisdictional claims and institutional affiliations. The authors of the article are Dayanand Kumar, Hanrui Li, Dhananjay D. Kumbhar, Manoj Kumar Rajbhar, Uttam Kumar Das, Abdul Momin Syed, Georgian Melinte, and Nazek El-Atab. [Extracted from the article]

[Display omitted] • Development and identification of a novel ion pair sensor H 2 L via supramolecular assembly. • As an ion pair, the probe can detect ZnCl 2 and AlCl 3 in 9:1 DMSO-water medium. • In a pure aqueous medium, it can detect Cl− among several competitive anions. • 1:1 probe analyte binding is confirmed by the mass and NMR spectral study. • The probe can detect and quantify the Al in the market-available drug samples. The work reports the development of a novel pyridine 2, 6 diamide spacer acyl hydrazone-based dual sensor H 2 L via two intermediates 1 and 2. The sensor as well as intermediates have been spectroscopically characterized. The structure of intermediate 1 is validated by its single crystal data analysis. As H 2 L bears both amide and acyl hydrazone moiety which have selective detection ability of anion and cation respectively, after rigorous characterization, the sensors are exposed to check their dual binding behavior. The results of several spectroscopic studies disclose the fact that H 2 L can optically and fluorometrically detect Al (III) and Zn (II) among several competitive cations and Cl− among competitive anions in semi-aqueous and aqueous medium respectively. Interestingly in a 9:1 DMSO-water medium, the probe can act as an ion pair sensor and in this medium, the probe can simultaneously detect Zn (II)/Cl- and Al (III)/Cl- forming H 2 L-ZnCl 2 , H 2 L-AlCl 3 adduct. The 1:1 probe-analyte ion-pair binding is confirmed by NMR and mass spectral study. The Density Functional Theory (DFT) study optimizes the structures of the probe-analyte complexes. Impressively the probe has the potential to detect and quantify the Al (III) from market-available drug samples. [ABSTRACT FROM AUTHOR]

[Display omitted] • A newly developed Chemosensor HL for effective detection of Zn(II) with the formation of complex 1 in presence of azide. • The fluorescence microscopic images of normal HEK cell assures the biomedical application of HL towards Zn(II) • Complex 1 haven been further utilized for easy detection of Al(III) ion with the formation of Zn-Al bimetal complex • An INHIBIT logic circuit is formed with two step sensing phenomena along with the formation of a molecular memory A schiff base chemosensor HL [4-chloro-(((2-(piperidine-1-yl)imino)methyl)phenol], constructed by one step condensation of 2-aminoethyl piperidine and 5- Chloro Salicylaldehyde is illustrated to have its usefulness for selective and sensitive detection of Zn(II) among other metal ions in aqueous solution (HEPES buffer) displaying the colour changes from light blue to turquoise under UV light. The specific detection phenomena of Zn (II) is monitored by the remarkable fluorescence enhancement and notable change in NMR spectral data of fluorescence active HL after addition of Zn(II) to it. The impressive high binding constant in 106 orders, determined by electronic spectral titration after introduction of Zn(II) to HL assure the formation of a Zinc complex during sensing phenomena. In order to check whether the nuclearity of the constructed complex can be increased or not fluorescence enhancement phenomenon is further monitored in presence of different bridging ligands and the results display that only in presence of azide a significant enhancement of Zn(II)- HL domain is exposed where as for other bridging ligand the spectra remain unaltered. This observation insists to conduct the reaction between HL and ZnCl 2 in presence of sodium azide which lead the formation of a Zn complex [Zn 2 (HL) 2 (N 3) 4 (complex 1) employing azide as the secondary anionic residue instead of bridging. The single crystal structure of the complex unveils the unique protonation of the piperidine N during the crystallization of the dinuclear motif of the complex 1. Furthermore the Zn complex due to the presence of remarkable luminescence property have been effectively used for selective sensing of Al(III) ion as metalloreceptor in HEPES buffer solution via turn of fluorescence with remarkable fluorescence quenching constant. In aqueous solution, complex 1 induces a 1:2 complex formation with Al(III) ion indicated by Job's plot analysis. The DFT study suggests the formation of bimetal complex during sensing of Al(III) with complex 1 as metalloreceptor. The in vitro cell imaging study gives a authentic hints for in vivo biomedical application of HL as a selective and easy Zn(II) sensor. The two step sensing phenomena of HL and complex 1 is further established by advanced molecular logic gate formation. [ABSTRACT FROM AUTHOR]

DMAP in water is applied for an intermolecular assembly of acetyl/benzoyl acetanilides (I) and alkynes (II) via a new [2-+ 2 + 2] and [3 + 2] cascade dual annulation. [ABSTRACT FROM AUTHOR]

The new complexes of compositions [(L)Cu] and [(L)Cu] were prepared by treating with 2-hydroxy-5-methyl-3-(2-aryldiazenyl)phenylimino) methyl) benzaldehyde (HL) and ethyl-2-cyano-3-(2-hydroxy-5-methyl-3-(-(2-aryldiazenyl) phenylimino) methyl) phenyl) acrylate (HL) ligands [where aryl is phenyl for HL $_{\mathrm {a}}^{\mathrm {~1 } }$ and HL $_{\mathrm {b}}^{~1}$; p-methyl phenyl for HL $_{\mathrm {a}}^{\mathrm {~2 } }$ and HL $_{\mathrm {b}}^{~2}$; and p-chloro phenyl for HL $_{\mathrm {a}}^{\mathrm {~3 } }$ and HL $_{\mathrm {b}}^{~3}$] with Cu(OAc).HO, respectively. Both the bis copper(II) complexes consist of tridentate (N,N,O) anionic ligands, L $_{\mathrm {a}}^{\mathrm {~-}}$ or L $_{\mathrm {b}}^{\mathrm {~-}}$. X-ray structures of the representative complexes [(L $_{\mathrm {a}}^{~1})_{2}$Cu] and [(L $_{\mathrm {b}}^{~2})_{2}$Cu] were determined to confirm the molecular species unequivocally. The molecular structure of copper complexes exhibited tetragonally distorted (Jahn-Teller) geometry consistent with the d configuration of Cu(II) metal ion. Oxidation of benzyl alcohols using the newly synthesized complexes as catalyst has been studied. Photoluminescence properties of [(L $_{\mathrm {a}}^{~2})_{2}$Cu] and [(L $_{\mathrm {b}}^{~2})_{2}$Cu] were exploited for selective cyanide recognition. The [(L)Cu], complexes displayed antibacterial activity toward gram positive and gram negative bacteria. [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR]

A receptor R1 was designed and synthesised for colorimetric detection of F− ions as well as Cu2+ ions via intramolecular charge transfer mechanism. Upon addition of F− ions in dry DMSO, the color of the receptor R1 changed from pale yellow to blue. The receptor showed a unique property of solvatochromism by displaying different coloration with different solvents only in the presence of F− ions, which were applied to determine the percentage composition of binary solvent mixtures. The receptor R1 was able to detect Cu2+ ions colorimetrically where it exhibited a color change from pale yellow to orange-red. In addition, the receptor was subjected to molecular logic gate applications, wherein it showed ‘ON–OFF’ switching operations. [ABSTRACT FROM AUTHOR]

Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. However, MEC arising in the minor salivary glands of the lower lip is extremely rare, and to date, only a few have been reported. In this study, we are reporting a case of MEC of the lower lip in a 60-year-old male patient. The patient presented with a slow growing mass in the lower lip for about three years with a recent history of an increase in size. Surgical excision and histopathological examination of the resected mass confirmed the diagnosis of low-grade MEC. We are presenting this case to highlight that although rare, MEC should be kept in mind in the differential diagnosis of any lip mass. [ABSTRACT FROM AUTHOR]

Abstract: Cobalt complexes of tetradentate amine–phenolate ligands were studied for their potential in coupling carbon dioxide with propylene oxide under neat reaction conditions. Cobalt(II) complexes afforded catalytic systems with higher TONs than analogous cobalt(III) compounds. Tetrabutylammonium bromide (TBAB) and PPN+N3 − were effective co-catalysts whereas N,N-dimethylaminopyridine (DMAP) shut down reactivity. Ligands containing a pendant pyridyl donor afforded more active catalysts than those containing dimethylamine groups. Reactions proceeded well at room temperature under moderate pressures of carbon dioxide. [Copyright &y& Elsevier]