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目的探讨颈动脉和下肢动脉粥样硬化分级与2型糖尿病(T2DM)患者心脑血管疾病风险的关系。方 法回顾性分析1 262例T2DM患者的临床资料，采集心脑血管疾病病史，采用血管多普勒超声检查颈动脉及下 肢动脉，通过动脉硬化分级进行评估，采用Logistic回归方程对颈动脉和下肢动脉粥样硬化分级与心脑血管疾病的 相关性进行分析。结果共1 139例患者临床资料纳人结果分析。颈动脉粥样硬化1级283例(24.8%)，2级198 例（17.4%)，3级546例（47.9%)，4级112例（9.8%);下肢动脉粥样硬化I级203例（17.8%)，2级218例 (19.1%)，3级654例(57.4%)，4级64例(5.6%)。颈动脉与下肢动脉粥样硬化分级具有一致性。有心血管事件 者113例(9.9%)，无心血管事件者1 026例(90.1%)，有脑血管事件者205例（18.0%)，无脑血管事件者934例 (82%)，同时有心血管事件及脑血管事件者76例(6.7%)。多因素Logistic回归分析结果显示与无颈动脉粥样硬 化和下肢动脉粥样硬化患者比较，颈动脉粥样硬化和下肢动脉粥样硬化3级和4级患者，心血管和脑血管疾病的 患病风险均增加(P均< 0.05)。心血管疾病患病风险与颈动脉、下肢动脉粥样硬化分级的一致性相关(OR = 2.84， P <0.05) e结论动脉硬化分级能够评估T2DM患者的颈动脉及下肢动脉的硬化程度，随着外周动脉粥样硬化 程度的增加，心脑血管疾病患病风险逐渐增髙，颈动脉或下肢动脉粥样硬化斑块形成或存在狭窄均是心脑血管疾 病患病的危险因素。 [ABSTRACT FROM AUTHOR]

Objective: To evaluate the nutritional status of the hospitalized patients with type 2 diabetes mellitus (T2DM) by controlling nutritional status (CONUT) score and to analyze the risk factors of malnutrition by multivariate Logistic regression. Methods: 454 cases of hospitalized patients with T2DM in our hospital from January 2021 to January 2022 were selected, and they were divided into malnutrition group with 68 cases and normal nutrition group with 386 cases according to CONUT score. The baseline data of patients were collected, and multivariate Logistic regression was used to analyze the risk factors of malnutrition in hospitalized patients with T2DM. Results: The incidence of malnutrition in 454 cases of hospitalized patients with T2DM was 14.98% (68/454). Univariate analysis showed that there were significant differences in glycated hemoglobin Alc (HbA1c), age, high density lipoprotein cholesterol (HDL-C), body mass index (BMI), C-reactive protein (CRP), course of disease, lymphocyte count, smoking, hemoglobin, albumin and 2 h postpran- dial blood glucose in the two groups (P<0.05). Multivariate Logistic regression analysis showed that decreased albumin, age greater than or equal to 60 years, decreased hemoglobin, decreased BMI, decreased HDL-C, prolonged course of disease, smoking and increased CRP were independent risk factors for malnutrition in hospitalized patients with T2DM (P<0.05). Conclusion: The incidence of malnutrition in hospitalized patients with T2DM is high. Age, BMI, course of disease, smoking, albumin, hemoglobin, HDL-C, CRP are independent influencing factors of malnutrition in hospitalized patients with T2DM. CONUT score can quickly screen the nutritional status of hospitalized patients with T2DM, which is helpful to guide clinical timely intervention. [ABSTRACT FROM AUTHOR]