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Your search keyword '"Paweska, Janusz"' showing total 2 results
Start Over Author "Paweska, Janusz" Topic biological evolution Topic hemorrhagic fever Database Academic Search Index
2 results on '"Paweska, Janusz"'

1. Virus detection and monitoring of viral load in Crimean-Congo hemorrhagic fever virus patients.

Author

Wölfel, Roman, Paweska, Janusz T., Petersen, Nadine, Grobbelaar, Antoinette A., Leman, Patricia A., Hewson, Roger, Georges-Courbot, Marie-Claude, Papa, Anna, Günther, Stephan, Drosten, Christian, Wölfel, Roman, and Günther, Stephan

Subjects
*HEMORRHAGIC fever, *POLYMERASE chain reaction, *VIRUS diseases, *SERUM, *VIRUSES, *INFECTION, *DIAGNOSIS, *PATIENTS, *REVERSE transcriptase polymerase chain reaction, *RESEARCH, *GENETICS, *BIOLOGICAL evolution, *VIRAL load, *RESEARCH methodology, *MEDICAL cooperation, *EVALUATION research, *COMPARATIVE studies, *IMMUNITY, *RNA viruses, *STANDARDS, RESEARCH evaluation
Abstract

We developed a real-time reverse transcription--PCR that detected 1,164 copies/mL of Crimean-Congo hemorrhagic fever virus per milliliter of serum at 95% probability (probit analysis) and was 100% concordant with nested PCR on 63 samples from 31 patients with confirmed infection. Infected patients who died appeared to have higher viral loads; low viral loads correlated with IgG detection. [ABSTRACT FROM AUTHOR]

Published
2007
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2. Studies of reservoir hosts for Marburg virus.

Author

Swanepoel, Robert, Smit, Sheilagh B., Rollin, Pierre E., Formenty, Pierre, Leman, Patricia A., Kemp, Alan, Burt, Felicity J., Grobbelaar, Antoinette A., Croft, Janice, Bausch, Daniel G., Zeller, Hervé, Leirs, Herwig, Braack, L. E. O., Libande, Modeste L., Zaki, Sherif, Nichol, Stuart T., Ksiazek, Thomas G., Paweska, Janusz T., Zeller, Hervé, and International Scientific and Technical Committee for Marburg Hemorrhagic Fever Control in the Democratic Republic of Congo

Subjects
*MARBURG virus, *ANIMALS, *MINES & mineral resources, *HEMORRHAGIC fever, *BATS, *BAT classification, *RESEARCH, *BIOLOGICAL evolution, *ANIMAL experimentation, *RESEARCH methodology, *RNA, *MEDICAL cooperation, *EVALUATION research, *COMPARATIVE studies, *RNA viruses, *VIRAL antibodies, *MINERAL industries
Abstract

To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998-2000. We found MARV nucleic acid in 12 bats, comprising 3.0%-3.6% of 2 species of insectivorous bat and 1 species of fruit bat. We found antibody to the virus in the serum of 9.7% of 1 of the insectivorous species and in 20.5% of the fruit bat species, but attempts to isolate virus were unsuccessful. [ABSTRACT FROM AUTHOR]

Published
2007
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