1. A new steroidal saponin from Polygonatum sibiricum.
- Author
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Zhang, Hong-Yang, Hu, Wei-Cheng, Ma, Guo-Xu, Zhu, Nai-Liang, Sun, Xiao-Bo, Wu, Hai-Feng, and Xu, Xu-Dong
- Subjects
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CELL lines , *COMPARATIVE studies , *HEPATOCELLULAR carcinoma , *LIVER tumors , *MEDICINAL plants , *MOLECULAR structure , *RESEARCH funding , *SPECTRUM analysis , *STEROIDS , *PHYTOCHEMICALS , *PLANT extracts , *CYTOTOXINS - Abstract
A new furostan type steroidal saponin, kingianoside Z (1), along with four known compounds (2-5), was isolated from the ethanolic extract of Polygonatum sibiricum Delar. ex Redoute. Their structures were determined by spectroscopical method and by comparison with previously reported spectroscopic data. Compounds 3-5 showed significant cytotoxicity against HepG2 cell lines with IC50 values of 14.2, 12.1 and 8.5 μM, respectively. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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