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Cytotoxic lanostane triterpenoids from the stems of Schisandra glaucescens.
- Source :
-
Journal of Asian Natural Products Research . Aug2018, Vol. 20 Issue 8, p727-733. 7p. - Publication Year :
- 2018
-
Abstract
- Phytochemical investigation on the stems of Schisandra glaucescens resulted into the isolation of three new lanostane triterpenoids, 12-hydroxyschiglausin B (1), 12-hydroxykadsuphilactone B (2), and 20R-hydroxyschinalactone C (3). Structural elucidation of all the compounds was accomplished by spectral methods. The isolated compounds were tested in vitro for cytotoxic activities. As a result, triterpenoids 1 and 2 showed cytotoxic activities for all six tested tumor cell lines with IC50 values less than 15 μM. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 20
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 133508449
- Full Text :
- https://doi.org/10.1080/10286020.2018.1492564