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Although the relationship between religion and football has gained considerable interest during the last twenty years, scant attention has been paid to the relationship between pilgrimage and football. This paper seeks to advance the study of this relationship through an exploration of collective memory about football disasters that throws fresh light on central themes within pilgrimage studies—pilgrimage as both a journey to a sacred place and the performance of diverse rituals at such places. The paper explores, in particular, the ways in which three different tragedies involving English football clubs have been commemorated through journeys to and ritual performance at places seen as sacred to those involved in commemoration—football stadiums and urban spaces, and cathedrals and pilgrimage shrines in England, Germany and Italy. Through this analysis, we seek to show how the commemoration of football disaster is linked to pilgrimage as a process where people seek healing and reconciliation through the public performance of rituals that link the local to the global. [ABSTRACT FROM AUTHOR]

In order to achieve the ambitious goal of "carbon neutrality", countries around the world are striving to develop clean energy. Against this background, this paper takes China and Italy as representatives of developing and developed countries to summarize the energy structure composition and development overview of the two countries. The paper analyzes the serious challenges facing the future energy development of both countries and investigates the possibilities of energy cooperation between the two countries, taking into account their respective advantages in energy development. By comparing the policies issued by the two governments to encourage clean energy development, this paper analyzes the severe challenges faced by the two countries' energy development in the future and combines their respective energy development advantages to look forward to the possibility of energy cooperation between the two countries in the future. This lays the foundation for China and Italy to build an "Energy Road" after the "Silk Road". [ABSTRACT FROM AUTHOR]

Before the COVID-19 pandemic, ventilation in buildings was not always given its due importance. The World Health Organization has highlighted the important role of air exchange with the outdoors in improving the air quality in buildings; buildings should, therefore, be equipped with mechanical ventilation or adequate air conditioning systems. This paper aims to investigate different retrofit solutions for air conditioning, evaluating them in terms of energy consumption and cost and the impact of increased outdoor air exchange rates on countering the propagation of COVID-19; the latter is the main novelty of the paper. As a case study, we take an existing office building located in Central Italy that was previously not equipped with a mechanical ventilation system (a system with primary air was introduced during the study). The energy analysis was conducted using dynamic simulation software after validation through energy bills; energy and economic analyses were conducted considering different external-air exchange rates. An optimal number of outdoor air changes was found to mitigate the risk of COVID-19 infection, a finding in line with the international literature. The increase in air changes with outdoor air leads to a rise in energy consumption and costs. These values were evaluated for different air conditioning systems and operational schedules. These drawbacks can be made less significant by combining interventions in the system with energy-efficiency measures applied to the building envelope. [ABSTRACT FROM AUTHOR]

In the context of power system decarbonization, the demand-side strategy for increasing the share of renewable energy is studied for two constrained energy systems. This strategy, which is currently widely suggested in policies on the energy transition, would impact consumer behavior. Despite the importance of studying the latter, the focus here is on decisions regarding the type, location, and timeframe of implementing the related measures. As such, solutions must be assessed in terms of cost and feasibility, technological learning, and by considering geographical and environmental constraints. Based on techno-economic optimization, in this paper we analyze the evolution of the power system and elaborate plausible long-term trajectories in the energy systems of two European islands. The case studies, Procida in Italy and Hinnøya in Norway, are both electrically connected to the mainland by submarine cables and present issues in their power systems, which are here understood as relatively isolated power systems. Renewable energy integration is encouraged by legislative measures in Italy. Although not modeled here, they serve as a backbone for the assumptions of increasing these investments. For Procida, rooftop photovoltaics (PV) coupled with energy storage are integrated in the residential, public, and tertiary sectors. A price-based strategy is also applied reflecting the Italian electricity tariff structure. At a certain price difference between peak and off-peak, the electricity supply mix changes, favoring storage technologies and hence decreasing imports by up to 10% during peak times in the year 2050. In Norway, renewable energy resources are abundant. The analysis for Hinnøya showcases possible cross-sectoral flexibilities through electrification, leading to decarbonization. By fine-tuning electric vehicle charging tactics and leveraging Norway's electricity pricing model, excess electricity demand peaks can be averted. The conclusions of this double-prospective study provide a comparative analysis that presents the lessons learnt and makes replicability recommendations for other territories. [ABSTRACT FROM AUTHOR]

This paper presents an assessment of the levelized cost of clean hydrogen produced in Sicily, a region in Southern Italy particularly rich in renewable energy and where nearly 50% of Italy's refineries are located, making a comparison between on-site production, that is, near the end users who will use the hydrogen, and centralized production, comparing the costs obtained by employing the two types of electrolyzers already commercially available. In the study for centralized production, the scale factor method was applied on the costs of electrolyzers, and the optimal transport modes were considered based on the distance and amount of hydrogen to be transported. The results obtained indicate higher prices for hydrogen produced locally (from about 7 €/kg to 10 €/kg) and lower prices (from 2.66 €/kg to 5.80 €/kg) for hydrogen produced in centralized plants due to economies of scale and higher conversion efficiencies. How-ever, meeting the demand for clean hydrogen at minimal cost requires hydrogen distribution pipelines to transport it from centralized production sites to users, which currently do not exist in Sicily, as well as a significant amount of renewable energy ranging from 1.4 to 1.7 TWh per year to cover only 16% of refineries' hydrogen needs. [ABSTRACT FROM AUTHOR]

This paper presents a multi-objective optimization model for the integration of polygeneration systems into energy communities (ECs), by analyzing a case study. The concept of ECs is increasingly seen as beneficial for reducing global energy consumption and greenhouse gas emissions. Polygeneration systems have the potential to play a crucial role in this context, since they are known for producing multiple energy services from a single energy resource, besides the possibility of being fed also by renewable energy sources. However, optimizing the configuration and operation of these systems within ECs presents complex challenges due to the variety of technologies involved, their interactions, and the dynamic behavior of buildings. Therefore, the aim of this work is developing a mathematical model using a mixed integer linear programming (MILP) algorithm to optimally design and operate polygeneration systems integrated into ECs. The model is applied to a case study of an EC comprising nine buildings in a small city in the northeast of Italy. The work rests on the single- and multi-objective optimization of the polygeneration systems taking into account the sharing of electricity among the buildings (both self-produced and/or the purchased from the grid), as well as the sharing of heating and cooling between the buildings through a district heating and cooling network (DHCN). The main results from the EC case study show the possibility of reducing the total annual CO2 emissions by around 24.3% (about 1.72 kt CO2/year) while increasing the total annual costs by 1.9% (about 0.09 M€/year) or reducing the total annual costs by 31.9% (about 1.47 M€/year) while increasing the total annual CO2 emissions by 2.2% (about 0.16 kt CO2/year). The work developed within this research can be adapted to different case studies, such as in the residential–commercial buildings and industrial sectors. Therefore, the model resulting from this work constitutes an effective tool to optimally design and operate polygeneration systems integrated into ECs. [ABSTRACT FROM AUTHOR]

Remote images are useful tools for detecting and monitoring landslides, including shallow landslides in agricultural environments. However, the use of non-commercial satellite images to detect the latter is limited because their spatial resolution is often comparable to or greater than landslide sizes, and the spectral characteristics of the pixels within the landslide body (LPs) are often comparable to those of the surrounding pixels (SPs). The buried archaeological remains are also often characterized by sizes that are comparable to image spatial resolutions and the spectral characteristics of the pixels overlying them (OBARPs) are often comparable to those of the pixels surrounding them (SBARPs). Despite these limitations, satellite images have been used successfully to detect many buried archaeological remains since the late 19th century. In this research context, some methodologies, which examined the values of OBARPs and SBARPs, were developed to rank images according to their capability to detect them. Based on these previous works, this paper presents an updated methodology to detect shallow landslides in agricultural environments. Sentinel-2 and Google Earth (GE) images were utilized to test and validate the methodology. The landslides were mapped using GE images acquired simultaneously or nearly simultaneously with the Sentinel-2 data. A total of 52 reference data were identified by monitoring 14 landslides over time. Since remote sensing indices are widely used to detect landslides, 20 indices were retrieved from Sentinel-2 images to evaluate their capability to detect shallow landslides. The frequency distributions of LPs and SPs were examined, and their differences were evaluated. The results demonstrated that each index could detect shallow landslides with sizes comparable to or smaller than the spatial resolution of Sentinel-2 data. However, the overall accuracy values of the indices varied from 1 to 0.56 and two indices (SAVI and RDVI) achieved overall accuracy values equal to 1. Therefore, to effectively distinguish areas where shallow landslides are present from those where they are absent, it is recommended to apply the methodology to many image processing products. In conclusion, given the significant impact of these landslides on agricultural activity and surrounding infrastructures, this methodology provides a valuable tool for detecting and monitoring landslide presence in such environments. [ABSTRACT FROM AUTHOR]

Muslims in Italy are an increasingly large and relevant part of the social fabric, although their social condition is still characterized by a "precarious" status. This is explained by a relationship with State institutions that is not yet fully defined in formal terms and by resistance to legitimizing their presence in the public space. In addition, international events have led to the spread of a securitarian political rhetoric and to the intensification of "control" devices on the organized forms and public manifestations of Muslim religiosity. One issue that has concerned political interlocutors has been the training of "imams". This paper presents the Italian case of training "on" and "of" Islam, analyzing it as a contested field, albeit in a not open and hostile form, between the different social and institutional actors, that is Italian universities, Islamic organizations and transnational Islam and Islam "of the States". It then analyzes the approach that has been developed and experimented by an Italian State university for the training of imams and murshidat, in collaboration with Italian Islamic organizations and some universities in the Organization of Islamic Cooperation countries, and it also discusses how it fits in as a possible innovative model among the various "assemblages" that have emerged in Europe in recent years. [ABSTRACT FROM AUTHOR]

This paper addresses the problem of removing 3D effects as one of the most challenging problems related to 2D electrical resistivity tomography (ERT) monitoring of embankment structures. When processing 2D ERT monitoring data measured along linear profiles, it is fundamental to estimate and correct the distortions introduced by the non-uniform 3D geometry of the embankment. Here, I adopt an iterative 3D correction plus 2D inversion procedure to correct the 3D effects and I test the validity of the proposed algorithm using both synthetic and real data. The modelled embankment is inspired by a critical section of the Parma River levee in Colorno (PR), Italy, where a permanent ERT monitoring system has been in operation since November 2018. For each model of the embankment, reference synthetic data were produced in Res2dmod and Res3dmod for the corresponding 2D and 3D models. Using the reference synthetic data, reference 3D effects were calculated to be compared with 3D effects estimated by the proposed algorithm at each iteration. The results of the synthetic tests showed that even in the absence of a priori information, the proposed algorithm for correcting 3D effects converges rapidly to ideal corrections. Having validated the proposed algorithm through synthetic tests, the method was applied to the ERT monitoring data in the study site to remove 3D effects. Two real datasets from the study site, taken after dry and rainy periods, are discussed here. The results showed that 3D effects cause about ±50% changes in the inverted resistivity images for both periods. This is a critical artifact considering that the final objective of ERT monitoring data for such studies is to produce water content maps to be integrated in alarm systems for hydrogeological risk mitigation. The proposed algorithm to remove 3D effects is thus a rapid and validated solution to satisfy near-real-time data processing and to produce reliable results. [ABSTRACT FROM AUTHOR]

Background: Potentially inappropriate polypharmacy (PIP) is among the major factors leading to adverse drug reactions, increased healthcare costs, reduced medication adherence, and worsened patient conditions. This study aims to identify existing interventions implemented to monitor and manage polypharmacy in the Italian setting. Methods: A systematic literature review (PROSPERO: CRD42023457049) was carried out according to the PRISMA statement guidelines. PubMed, Embase, ProQuest, and Web of Science were queried without temporal constraints, encompassing all published papers until October 2023. Inclusion criteria followed the PICO model: patients with polypharmacy; interventions to monitor/manage polypharmacy regimen versus no/any intervention; outcomes in terms of intervention effectiveness and cost variation. Results: After duplicate deletion, 153 potentially relevant publications were extracted. Following abstract and full-text screenings, nine articles met the inclusion criteria. Overall, 78% (n = 7) were observational studies, 11% (n = 1) were experimental studies, and 11% (n = 1) were two-phase studies. A total of 44% (n = 4) of the studies involved patients aged ≥ 65 years, while 56% (n = 5) were disease-specific. Monitoring was the most prevalent choice of intervention (67%; n = 6). Outcomes were mainly related to levels of polypharmacy (29%; n = 6) and comorbidities (29%; n = 6), effectiveness rates (14%; n = 3), and avoidable costs (9%; n = 2). Conclusions: This review outlines that Italy is still lacking in interventions to monitor/manage PIP, addressing an unmet need in developing patient-tailored strategies for reducing health-system burden. [ABSTRACT FROM AUTHOR]

Air conditioning systems can play a positive or negative role in the spread of COVID-19 infection. The importance of sufficient outdoor air changes in buildings was highlighted by the World Health Organization, therefore these should be guaranteed by mechanical ventilation systems or adequate air conditioning systems. The proposed case study concerns the optimal number of outdoor air changes to limit COVID-19 contagion for a school building in Central Italy. The Wells–Riley model is used to assess the risk of airborne infection, while energy consumption is calculated by a dynamic energy simulation software. The scope of the paper offers an innovative method to define the optimal ventilation strategy for the building's HVAC system design to reduce the risk of infection with limited increases in energy consumption and greenhouse gas emissions. Results show that the desirable approach is the one in which the same low value of contagion risk is set in all rooms. This new approach results in significant energy savings, compared to the most common ones (setting the same high outdoor air rates for all rooms) to counteract the risk of infection. Finally, the zero-emission building target is verified by introducing a suitable photovoltaic system to offset pollutant emissions. [ABSTRACT FROM AUTHOR]

The prediction and prevention of landslide hazard is a challenging topic involving the assessment and quantitative evaluation of several elements: geological and geomorphological setting, rainfalls, and ground motion. This paper presents the multi-approach investigation of the Nevissano landslide (Asti Province, Piedmont, NW Italy). It shows a continuous and slow movement, alongside few paroxysmal events, the last recorded in 2016. The geological and geomorphological models were defined through a field survey. An inventory of the landslide's movements and rainfall records in the period 2000–2016 was performed, respectively, through archive investigations and the application of "Moving Sum of Daily Rainfall" method, allowing for the definition of rain thresholds for the landslide activation (105 mm and 193 mm, respectively, in 3 and 30 days prior to the event). The displacements over the last 8 years (2016–2023) were monitored through an innovative in-continuum monitoring inclinometric system and Earth Observation (EO) data (i.e., relying on Interferometric Synthetic Aperture Radar, or InSAR data): it gave the opportunity to validate the rainfall thresholds previously defined. This study aims to provide information to public authorities for the appropriate management of the site. Moreover, the proposed workflow could be adopted as a guideline for investigating similar situations. [ABSTRACT FROM AUTHOR]

This paper explores the development of pottery technology in the Trieste Karst region (North-East Italy) from the Neolithic to the Early Bronze Age (EBA). It also seeks to identify cultural links with other areas by examining potentially imported vessels. Archaeometric analyses (X-ray diffraction and optical microscopy) reveal significant differences between Neolithic ceramics (Danilo–Vlaška Group) and the majority of Late Copper Age (LCA)/Early Bronze Age (EBA) pottery (primarily associated with the Ljubljana Culture and a few with the Cetina Culture). Neolithic pottery displays consistent characteristics across all vessel types, including coarse grain, prevalent sparry calcite temper, and the absence of grog. In contrast, most LCA and EBA vessels exhibit distinct features such as very fine-grained paste, no sparry calcite, notable use of grog temper, higher quartz, muscovite, and flint content. Notably, from a technological perspective, the analyzed Cetina vessels bear a strong resemblance to the majority of LCA ceramics. The differences between Neolithic and LCA/EBA vessels clearly suggest the use of new raw materials, recipes, and techniques, likely reflecting changes in cultural and social contexts and potential connections with the core area of the Ljubljana Culture. [ABSTRACT FROM AUTHOR]

Background: The Carlevale lens (FIL SSF, Soleko IOL Division, Italy) is a new lens for suture-less scleral fixation. This paper aimed to systematically review articles on this lens, the surgical techniques used for its implantation, complications and outcomes. Methods: This systematic review was performed following the PRISMA guidelines. The search string used was "Carlevale" AND "scleral fixation" from inception until March 2024. For completeness, either case-control studies, case reports or case series written in English were included. The authors used the Newcastle–Ottawa scale for the case-control studies and the JBI Critical Appraisal Checklist for case reports and case series. Results: Twenty-nine articles were included. Scleral fixation with Carlevale lens can be performed by creating scleral flaps or, alternatively, by using scleral pockets. The two sclerotomies must be diametrically opposed, and are preferably created by 25-gauge trocars. A pars plana vitrectomy should be performed every time, and the design of the lens should be suitable for self-anchoring to the sclera; the most accredited strategy to achieve this is to avoid scleral sutures. There were only a few intraoperative and postoperative complications reported; vitreous hemorrhages were the most frequent intraoperative events, while the most relevant postoperative complications were vitreous hemorrhages, cystoid macular oedema and transient variations in the intraocular pressure. Excellent results have been obtained in terms of BCVA, IOL centration and stability, mean intraocular pressure, postoperative spherical equivalent, separation between anterior and posterior chamber and the distance of the IOL from anterior chamber structures. Conclusions: The foldable hydrophilic design of the Carlevale lens has shown good effectiveness, IOL stability and few intra and post-operative complications. [ABSTRACT FROM AUTHOR]

The Italian shellfish industry mainly comprises clams, mussels, and oysters. While clam production thrives and Italy leads Europe, mussel farming faces economic challenges. Oyster production is relatively new and holds potential. Sustainable development is crucial for meeting growing seafood demand while ensuring resource conservation and food safety. This paper, part of the VALUE-SHELL project funded by the Italian Ministry of Agriculture, Food Sovereignty and Forests (MASAF) as part of support activities for the National Strategic Plan of Aquaculture, combines desk research on industry structure and public interventions using a collaborative approach involving stakeholder interviews and focus groups with producers and local entities to assess the sector's most compelling needs. The collaborative process highlighted key challenges across the following four sustainability pillars: environmental (global warming, predator control, and pollution mitigation are critical concerns for ecosystem balance); economic (increased production costs and limited diversification opportunities affect profitability); social (fear of generational decline due to limited training and education opportunities poses a threat to the industry's future); and institutional (lack of a dedicated aquaculture law and fragmented governance hinder long-term planning). The project identifies policy bottlenecks hindering the sector's potential, caused by not fully addressing producer needs. Sustainable development strategies are essential for addressing these challenges and ensuring the Italian shellfish industry's future. [ABSTRACT FROM AUTHOR]

The accurate prediction of heavy precipitation in convective environments is crucial because such events, often occurring in Italy during the summer and fall seasons, can be a threat for people and properties. In this paper, we analyse the impact of satellite-derived surface-rainfall-rate data assimilation on the Weather Research and Forecasting (WRF) model's precipitation prediction, considering 15 days in summer 2022 and 17 days in fall 2022, where moderate to intense precipitation was observed over Italy. A 3DVar realised at CNR-ISAC (National Research Council of Italy, Institute of Atmospheric Sciences and Climate) is used to assimilate two different satellite-derived rain rate products, both exploiting geostationary (GEO), infrared (IR), and low-Earth-orbit (LEO) microwave (MW) measurements: One is based on an artificial neural network (NN), and the other one is the operational P-IN-SEVIRI-PMW product (H60), delivered in near-real time by the EUMETSAT HSAF (Satellite Application Facility in Support of Operational Hydrology and Water Management). The forecast is verified in two periods: the hours from 1 to 4 (1–4 h phase) and the hours from 3 to 6 (3–6 h phase) after the assimilation. The results show that the rain rate assimilation improves the precipitation forecast in both seasons and for both forecast phases, even if the improvement in the 3–6 h phase is found mainly in summer. The assimilation of H60 produces a high number of false alarms, which has a negative impact on the forecast, especially for intense events (30 mm/3 h). The assimilation of the NN rain rate gives more balanced predictions, improving the control forecast without significantly increasing false alarms. [ABSTRACT FROM AUTHOR]

The Euganean Thermal District, situated in North-East Italy, is one of Europe's largest and oldest thermal centres. The topical application of its therapeutic thermal muds is recognised by the Italian Health System as a beneficial treatment for patients suffering from arthro-rheumatic diseases. Polysaccharides produced by the mud microbiota have been recently identified as anti-inflammatory bioactive molecules. In this paper we analysed the efficacy of Microbial-Polysaccharides (M-PS) derived from mature muds obtained at different maturation temperatures, both within and outside the codified traditional mud maturation range. M-PSs were extracted from six mature muds produced by five spas of the Euganean Thermal District and investigated for their chemical properties, monosaccharide composition and in vivo anti-inflammatory potential, using the zebrafish model organism. Additionally, mature muds were characterized for their microbiota composition using Next-Generation Sequencing. The results showed that all M-PSs exhibit similar anti-inflammatory potential, referable to their comparable chemical composition. This consistency was observed despite changes in cyanobacteria populations, suggesting a possible role of the entire microbial community in shaping the properties of these biomolecules. These findings highlight the importance of scientific research in untangling the origins of the therapeutic efficacy of Euganean Thermal muds in the treatment of chronic inflammatory conditions. [ABSTRACT FROM AUTHOR]

This paper's research question is to evaluate the potential impact of large numbers of battery electric vehicles (BEVs) on the future electric grid, and whether the flexibility of BEV charging can induce enough system benefits to remunerate BEV users for the change in their recharging pattern. The considered scenario refers to the Italian situation and what might occur through the year 2040, where a share of BEV stock of 40% can be foreseen, as well as significant increases in PV and wind generation. Although this study is focused on Italy, its results are applicable, with minor differences, to several EU countries. This paper first shows that the future impact of increasing penetration of BEVs appears to be compatible with the expected growth of generation from renewable energy sources (RES) and the corresponding reduction in fossil fuel-based generation. It also gives an estimate of the CO2 emission reduction resulting from these changes, considering an unmanaged BEV charge profile and two different managed profiles that shift the car's charging period to hours of the day when they have no negative impact on the grid and maximize the utilization of RES. Finally, it shows an evaluation of the economic benefits of displacing private car charging ranging from 4 to 10 cEUR/kWh, which could be used as tariff incentives to stimulate this displacing in recharging time. [ABSTRACT FROM AUTHOR]

Since people tend to spend more and more time visiting museums, more accurate requirements are needed for the indoor environmental conditions of these confined spaces where two primary requisites coincide in defining their optimal indoor microclimate: the need for the appropriate artwork preservation and suitable levels of indoor comfort conditions for people visiting the exhibition buildings and/or working there. Regrettably, people and artwork requirements are sometimes characterized by different reference limits of the environmental parameters that, not rarely, could potentially conflict. Another important point to consider is that museums hosted by heritage buildings (particularly in Mediterranean climates, as is often the case in Italy) are often not equipped with climatization systems because of difficulty in installing generally bulky equipment such as HVAC systems. This circumstance represents another important limit for achieving suitable conditions for the two requisites. In addition, the recent pandemic-related occurrences are pushing technicians and designers to rethink the criteria for controlling the microclimate of public buildings, and museums among them. In this paper, this issue is addressed by reviewing current regulations, standards, and handbooks (and by means of a real case example related to the Italian context) in order to ascertain whether such documentation could facilitate the development of effective rules/guidelines for proper management of indoor parameters in museums. [ABSTRACT FROM AUTHOR]

This paper presents a novel approach to estimating short-term production of wind farms, which are made up of numerous turbine generators. It harnesses the power of big data through a blend of data-driven and model-based methods. Specifically, it combines an Artificial Neural Network (ANN) for immediate future predictions of wind turbine power output with a stochastic model for dependability, using Hybrid Reliability Block Diagrams. A thorough state-of-the-art review has been conducted in order to demonstrate the applicability of an ANN for non-linear stochastic problems of energy or power forecast estimation. The study leverages an innovative cluster analysis to group wind turbines and reduce the computational effort of the ANN, with a dependability model that improves the accuracy of the data-driven output estimation. Therefore, the main novelty is the employment of a hybrid model that combines an ANN with a dependability stochastic model that accounts for the realistic operational scenarios of wind turbines, including their susceptibility to random shutdowns This approach marks a significant advancement in the field, introducing a methodology which can aid the design and the power production forecast. The research has been applied to a case study of a 24 MW wind farm located in the south of Italy, characterized by 28 turbines. The findings demonstrate that the integrated model significantly enhances short-term wind-energy production estimation, achieving a 480% improvement in accuracy over the solo-clustering approach. [ABSTRACT FROM AUTHOR]

Due to increasing urbanization, nowadays, cities are facing challenges spanning multiple domains such as mobility, energy, environment, etc. For example, to reduce traffic congestion, energy consumption, and excessive pollution, big data gathered from legacy systems (e.g., sensors not conformant with modern standards), geographic information systems, gateways of public administrations, and Internet of Things technologies can be exploited to provide insights to assess the current status of a city. Moreover, the possibility to perform what-if analyses is fundamental to analyzing the impact of possible changes in the urban environment. The few available solutions for scenario definitions and analyses are limited to addressing a single domain and providing proprietary formats and tools, with scarce flexibility. Therefore, in this paper, we present a novel scenario model and editor integrated into the open-source Snap4City.org platform to enable several processing and what-if analyses in multiple domains. Different from state-of-the-art software, the proposed solution responds to a series of identified requirements, implements NGSIv2-compliant data models with formal descriptions of the urban context, and a scenario versioning method. Moreover, it allows us to carry out analyses on different domains, as shown with some examples. As a case study, a traffic congestion analysis is provided, confirming the validity and usefulness of the proposed solution. This work was developed in the context of CN MOST, the National Center on Sustainable Mobility in Italy, and for the Tourismo EC project. [ABSTRACT FROM AUTHOR]

Equine hepacivirus (EqHV, Flaviviridae, hepacivirus) is a small, enveloped RNA virus generally causing sub-clinical hepatitis with occasional fatalities. EqHV is reported in equids worldwide, but for Italy data are limited. To address this, a survey study was set up to estimate prevalence at a national level and among different production categories (equestrian; competition; work and meat; reproduction) and national macro-regions (North, Central, South, and Islands). Data obtained testing 1801 horse serum samples by Real-Time RT PCR were compared within the categories and regions. The NS3 fragment of the PCR-positive samples was sequenced by Sanger protocol for phylogenetic and mutational analysis. The tertiary structure of the NS3 protein was also assessed. The estimated national prevalence was 4.27% [1.97–6.59, 95% CI] and no statistical differences were detected among production categories and macro-regions. The phylogenesis confirmed the distribution in Italy of the three known EqHV subtypes, also suggesting a possible fourth sub-type that, however, requires further confirmation. Mutational profiles that could also affect the NS3 binding affinity to the viral RNA were detected. The present paper demonstrates that EqHV should be included in diagnostic protocols when investigating causes of hepatitis, and in quality control protocols for blood derived products due to its parental transmission. [ABSTRACT FROM AUTHOR]

Xylella Fastidiosa has been recently detected for the first time in southern Italy, representing a very dangerous phytobacterium capable of inducing severe diseases in many plants. In particular, the disease induced in olive trees is called olive quick decline syndrome (OQDS), which provokes the rapid desiccation and, ultimately, death of the infected plants. In this paper, we analyse about two thousands pixels of MODIS satellite evapotranspiration time series, covering infected and uninfected olive groves in southern Italy. Our aim is the identification of Xylella Fastidiosa-linked patterns in the statistical features of evapotranspiration data. The adopted methodology is the well-known Fisher–Shannon analysis that allows one to characterize the time dynamics of complex time series by means of two informational quantities, the Fisher information measure (FIM) and the Shannon entropy power (SEP). On average, the evapotranspiration of Xylella Fastidiosa-infected sites is characterized by a larger SEP and lower FIM compared to uninfected sites. The analysis of the receiver operating characteristic curve suggests that SEP and FIM can be considered binary classifiers with good discrimination performance that, moreover, improves if the yearly cycle, very likely linked with the meteo-climatic variability of the investigated areas, is removed from the data. Furthermore, it indicated that FIM exhibits superior effectiveness compared to SEP in discerning healthy and infected pixels. [ABSTRACT FROM AUTHOR]

Anti-trafficking programmes in Italy have been implemented for more than two decades. Yet, little empirical evidence is available regarding their functioning. This paper draws on 56 semi-structured interviews carried out in the period of 2019–2021 with practitioners and beneficiaries of the N.A.Ve anti-trafficking programme. The interviews focused on practitioners' experience working with Nigerian women and on Nigerian women's experiences of the programme upon completion. By building on critical anti-trafficking studies and the autonomy of migration perspective, this contribution looks at the relationship between practitioners and Nigerian women admitted to the programme by addressing the following questions: what is the experience of practitioners and beneficiaries in the N.A.Ve programme? To what extent is the structural violence of the counter-trafficking apparatus reproduced in the relational dynamics between practitioners, particularly Case Managers, and beneficiaries? How do beneficiaries cope with such violence? I argue that the Case Managers' approach builds on "stratified layers of institutional knowledge" and that this concept is useful to highlight how their knowledge derives both from the counter-trafficking apparatus and their social work background. Furthermore, I present evidence that such an approach reproduces structural violence through processes of "conditional inclusion". Nigerian women denounced this violence but also seized the relational capital grown from rapport, calling for more engagement with people rather than programme objectives. [ABSTRACT FROM AUTHOR]

Simple Summary: Completion lobectomy (CL) entails the resection of the remaining pulmonary lobe subsequent to wedge resection or segmentectomy. Indications for CL include reoperations for multiple or relapsed lung cancers and metastatic lung tumors, and the prognostic advantage of these procedures has been widely reported. However, ipsilateral surgical treatments, particularly within the same lobe, present challenges due to the development of intrapleural adhesions, rendering reoperation more difficult and time-consuming. VATS has emerged as the gold standard in the surgical treatment of early-stage NSCLC, offering superior postoperative outcomes when compared to thoracotomy. Its efficacy has been well established, even during complex procedures. However, its application in ipsilateral reoperations remains anecdotal, and to the best of our knowledge, no studies have analyzed the safety and efficacy of uniportal-VATS in this setting. This paper aims to evaluate the role of iniportal-VATS in CL long after wedge resection or anatomical segmentectomy in the same lobe. Background: Completion lobectomy (CL) following a prior resection in the same lobe may be complicated by severe pleural or hilar adhesions. The role of uniportal video-assisted thoracoscopic surgery (U-VATS) has never been evaluated in this setting. Methods: Data were collected from two Italian centers. Between 2015 and 2022, 122 patients (60 men and 62 women, median age 67.7 ± 8.913) underwent U-VATS CL at least 4 weeks after previous lung surgery. Results: Twenty-eight (22.9%) patients were affected by chronic obstructive pulmonary disease (COPD) and twenty-five (20.4%) were active smokers. Among the cohort, the initial surgery was performed using U-VATS in 103 (84.4%) patients, triportal-VATS in 8 (6.6%), and thoracotomy in 11 (9.0%). Anatomical segmentectomy was the initial surgery in 46 (37.7%) patients, while hilar lymphadenectomy was performed in 16 (13.1%) cases. CL was performed on 110 (90.2%) patients, segmentectomy on 10 (8.2%), and completion pneumonectomy on 2 (1.6%). Upon reoperation, moderate pleural adhesions were observed in 38 (31.1%) patients, with 2 (1.6%) exhibiting strong adhesions. Moderate hilar adhesions were found in 18 (14.8%) patients and strong adhesions in 11 (9.0%). The median operative time was 203.93 ± 74.4 min. In four (3.3%) patients, PA taping was performed. One patient experienced intraoperative bleeding that did not require conversion to thoracotomy. Conversion to thoracotomy was necessary in three (2.5%) patients. The median postoperative drainage stay and postoperative hospital stay were 5.67 ± 4.44 and 5.52 ± 2.66 days, respectively. Postoperative complications occurred in 34 (27.9%) patients. Thirty-day mortality was null. Histology was the only factor found to negatively influence intraoperative outcomes (p = 0.000). Factors identified as negatively impacting postoperative outcomes at univariate analyses were male sex (p = 0.003), age > 60 years (p = 0.003), COPD (p = 0.014), previous thoracotomy (p = 0.000), previous S2 segmentectomy (p = 0.001), previous S8 segmentectomy (p = 0.008), and interval between operations > 5 weeks (p= 0.005). In multivariate analysis, only COPD confirmed its role as an independent risk factor for postoperative complications (HR: 5.12, 95% CI (1.07–24.50), p = 0.04). Conclusions: U-VATS CL seems feasible and safe after wedge resection and anatomical segmentectomy. [ABSTRACT FROM AUTHOR]

Simple Summary: There is increasing interest in the study of how the ongoing climate change is affecting insect populations. However, most research has been focused on a limited number of groups that are particularly charismatic or expected to respond more clearly to climate change. Moreover, most research has been developed in a few areas (especially northern and central European countries), while others (such as the Mediterranean basin) have been largely overlooked. Therefore, more empirical research is needed, particularly on less charismatic species, groups that are expected to react less dramatically to climatic change, and key areas that are still poorly investigated. This study investigates changes in distributional and activity patterns in a common, ecologically tolerant, forest tenebrionid beetle in a region (central Italy) within the Mediterranean biodiversity hotspot, an area strongly subjected to the ongoing climate change, but for which research is still limited. By analyzing changes in elevation, latitude, longitude, and seasonal activity between 1900–1980 and 1981–2022, the results provided insights into the potential effects of climate change on this species. The beetle's average values of elevation and latitude were found to have been increased in the second period. In response to rising temperatures, the species became more frequent at higher elevation and in northern places. No strong evidence was found for an earlier species seasonal activity, but this could be due to the inclusion in the analysis of likely overwintering individuals. The findings suggest that even thermally tolerant species can undergo distributional shifts in elevation and latitude, even at a relatively small scale. There is an increasing volume of literature on the impact of climate change on insects. However, there is an urgent need for more empirical research on underrepresented groups in key areas, including species for which the effects of climatic change may seem less evident. The present paper illustrates the results of a study on a common forest tenebrionid beetle, Accanthopus velikensis (Piller and Mitterpacher, 1783), at a regional scale within the Mediterranean basin. Using a large set of records from Latium (central Italy), changes in the median values of elevation, latitude, longitude, and phenology between two periods (1900–1980 vs. 1981–2022) were tested. Records of A. velikensis in the period 1981–2022 showed median values of elevation and latitude higher than those recorded in the first period. Thus, in response to rising temperatures, the species became more frequent at higher elevation and in northern places. By contrast, A. velikensis does not seem to have changed its activity pattern in response to increased temperatures, but this might be an artifact due to the inclusion of likely overwintering individuals. The results obtained for A. velikensis indicate that even thermally euryoecious species can show changes in their elevational and latitudinal distribution, and that poleward shifts can be apparent even within a small latitudinal gradient. [ABSTRACT FROM AUTHOR]

Analysis of a series of thermal mappings obtained by UAS flights on quiescent volcanoes requires some special techniques to be performed. The main challenge is represented by the difficulty of separating hot and cold pixels in areas where their temperatures are quite similar. This task is indeed much simpler, for example, for lava flows where the temperature differences between the hot lava and the cold soil is rather big. This paper shows various software developed in order to perform this extraction and calculate the trends over time of both the average temperature and the heat flux from the soil. This prototypal implementation used thermal flights performed over a time span of a few years on an area in the Campi Flegrei caldera in southern Italy. Standard image manipulation techniques were used to segmentate and clusterise each thermal mapping in order to reduce the thermal anomalies to some sets of simpler features characterised by their fundamental parameters. The temporal trends of some physical parameters (temperature, heat flux, etc.) were extracted from these sets, and we found interesting results necessary for correlations and for ongoing research with other parameters. [ABSTRACT FROM AUTHOR]

Efficient management of renewable energy resources is imperative for promoting environmental sustainability and optimizing the utilization of clean energy sources. This paper presents a pioneering European-scale study on energy management within renewable energy communities (RECs). With a primary focus on enhancing the social welfare of the community, we introduce a reinforcement learning (RL) controller designed to strategically manage Battery Energy Storage Systems (BESSs) and orchestrate energy flows. This research transcends geographical boundaries by conducting an extended analysis of various energy communities and diverse energy markets across Europe, encompassing different regions of Italy. Our methodology involves the implementation of an RL controller, leveraging optimal control theory for training and utilizing only real-time data available at the current time step during the test phase. Through simulations conducted in diverse contexts, we demonstrate the superior performance of our RL agent compared to a state-of-the-art rule-based controller. The agent exhibits remarkable adaptability to various scenarios, consistently surpassing existing rule-based controllers. Notably, we illustrate that our approach aligns with the intricate patterns observed in both Italian and European energy markets, achieving performance levels comparable to an optimal controller assuming perfect theoretical knowledge of future data. [ABSTRACT FROM AUTHOR]

The electrification of transport is expected to progressively replace significant shares of light duty mobility, especially in large cities. The European Alternative Fuel Infrastructure Regulation (AFIR) aims to drive the adoption of electric mobility by establishing specific targets for charging point deployment. Innovative charging concepts may complement and accelerate the uptake of this fundamental part of the urban mobility transition. In this paper, one such innovative concept is described and its potential impact is assessed. The core idea involves integrating charging points into existing city tramway infrastructures. Turin's tramway network is taken as a representative case study. The proposed technical solution encompasses a charging hub powered by four isolated DC/DC converters of 50 kW, directly connected to the DC tramway distribution line. Three of these constitute the heart of a 150 kW charger, while the fourth acts as voltage regulator. This native DC installation greatly simplifies the architecture of the DC chargers. Using a conservative approach, it was estimated that a single recharging station could charge more than 60 vehicles daily. This highly scalable and replicable solution, with the potential for over 100 conversion substations across Italy, would enable the installation of numerous high-power chargers in urban settings. Furthermore, additional benefits could be realized through enhanced recovery of kinetic energy from trams, which is currently dissipated on-board. [ABSTRACT FROM AUTHOR]

The crafts sector, traditionally characterized by its adherence to heritage and small-scale familial enterprises, confronts an array of unprecedented challenges stemming from rapid technological advancement, globalization, climate change, and shifting demographics. This article presents a pioneering investigation into the profound and transformative effects of digitalization on the crafts sector, offering novel insights into the future trajectory of this industry. Through an explorative approach, we critically examine and interrogate the social imaginary underpinning the crafts sector, shedding light on the intricate interplay between tradition and innovation. Leveraging an inter- and transdisciplinary framework, our research brings together academics, experts, and practitioners from diverse regions in Italy and Austria to explore the nexus of digitalization and craft futures. We introduce three future scenarios for the crafts sector, each delineating varying degrees of digitalization and their potential implications. Employing a mixed-method approach encompassing expert interviews, a Delphi survey, focus groups, and scenario development, our study offers a comprehensive exploration of the multifaceted landscape of craft futures. Furthermore, through the visualization of these scenarios, we provide a tangible platform for envisioning and engaging with the myriad possibilities that lie ahead. By synthesizing innovative methodologies from future studies and social imaginaries with a specific focus on the crafts sector, our research offers a robust analytical framework for navigating the complex dynamics of digitalization and envisioning transformative futures. This paper not only illuminates the disruptive forces unleashed by digitalization but also provides strategic insights to inform future decision-making processes within the crafts sector and beyond. [ABSTRACT FROM AUTHOR]

Simple Summary: Nowadays, the infraorder Delphinida consists of oceanic dolphins and porpoises plus a handful of riverine and (sub-)Arctic forms. Overall, the delphinidans account for more than half of the living cetacean species, thus comprising the core of present-day marine mammal diversity. The fossil record indicates that a critical phase of the evolutionary history of Delphinida occurred during the Early Miocene (c. 23.0–16.0 million years ago) when the extinct genus Kentriodon first appeared and became widespread worldwide. Our paper deals with a new delphinidan fossil from northeastern Italy, namely, an incomplete skull with ear bones dating back to 20.4–19.0 million years ago. This new specimen is recognized herein as a representative of Kentriodon and specifically as the first unambiguous member of this genus from the Euro-Mediterranean region. Our new find represents the best candidate for being the most ancient member of Kentriodon. The evolutionary success of Kentriodon (which lasted until the Late Miocene, less than 11.3 million years ago) may have been favored by the evolution of a peculiar biosonar system exploiting narrow-band high-frequency sounds, which in turn would have been hardly detectable by large-bodied, predatory toothed whales. Furthermore, Kentriodon was seemingly characterized by a proportionally larger brain compared to many coeval toothed whales, which in turn may evoke enhanced behavioral capabilities. Nowadays, the infraorder Delphinida (oceanic dolphins and kin) represents the most diverse extant clade of Cetacea, with delphinids alone accounting for more than 40% of the total number of living cetacean species. As for other cetacean groups, the Early Miocene represents a key interval for the evolutionary history of Delphinida, as it was during this time span that the delphinidans became broadly distributed worldwide, first and foremost with the widespread genus Kentriodon and closely related forms. Here, we report on a new odontocete find from Burdigalian (20.4–19.0 Ma) deposits of the Friulian-Venetian Basin of northeastern Italy, consisting of the partial cranium of a small delphinidan with associated ear bones (right periotic, stapes, malleus and tympanic bulla). Osteoanatomical considerations and comparisons allow us to assign the studied specimen to the genus Kentriodon. This is the first confirmed record of Kentriodon from Europe as well as from the whole proto-Mediterranean region. Stratigraphic and phylogenetic considerations suggest that our new specimen may represent the geologically oldest member of Kentriodon. The evolutionary success of Kentriodon may correlate with the emergence of narrow-band high-frequency echolocation as a possible strategy to escape acoustic detection by large marine predators such as the squalodontids. In addition, the relatively high encephalization quotient of Kentriodon spp. may have provided these early dolphins with some kind of competitive advantage over the coeval non-delphinidan odontocetes. [ABSTRACT FROM AUTHOR]

As buildings are one of the major contributors to greenhouse gas emissions and energy consumption, they have a key potential for energy efficiency and indoor environmental quality improvement. Therefore, the development of nearly Zero-Energy Buildings (nZEBs) is strategic to respond to these challenges and to design and retrofit sustainable highly performing buildings. Actually, the nZEB target can also be reached with highly insulated wooden technologies. However, they must be critically revised and adapted when taking into account the warm climate peculiarities. The paper contributes to this attempt by dealing with the implementation of a methodology specifically focused on the long-term assessment of the real building envelope performance. The methodology is applied to a recently built wooden nZEB detached single-story dwelling constructed in 2017 in central Italy. One year monitoring data were collected about the envelope in-field dynamic performance and the indoor microclimate and well-being conditions. The theoretical design-stage data and the monitored data were compared. The positive aspects as well as the critical issues of nZEB target in the Mediterranean climate context and the performance gap were underlined. Accordingly, the main aspects to be considered in the design of nZEBs envelope were highlighted. [ABSTRACT FROM AUTHOR]

Background: Differentiated thyroid carcinoma (DTC) has an excellent prognosis; however, advanced disease is associated with a worse prognosis and is relatively common. Surgery followed by RAI treatment remains the mainstream treatment for a large majority of patients with high- and intermediate-risk DTC, but its benefits should be carefully weighed against the potential for harm. The aim of this paper is to critically review the experience in treating advanced DTC at two tertiary referral centers in Italy. Methods: Retrospective analysis of 300 patients who underwent surgery for ADTC over 30 years. Results: The complication rate was 50.33%. A total of 135 patients (45%) remained at regular follow-up, 118 (87.4%) were alive, while 17 (12.6%) were deceased. The mean overall survival at 12 years was 84.8% with a mean of 238 months. Eleven patients (8.1%) experienced a relapse after a median of 13 months. Conclusions: ADTC patients adequately treated can achieve prolonged survival even in the case of metastasis or disease relapse. Patients with ADTC should be referred to high-volume centers with the availability of an extended multidisciplinary team to receive tailored treatment. [ABSTRACT FROM AUTHOR]

A source apportionment scheme based on gas and aerosol phase reactive tracers has been implemented in the chemical-transport model FARM, to efficiently estimate contributions of different sources to ambient concentrations. The on-line scheme deals with all the main processes that the chemical species undergo in the model, to enhance consistency with the calculation of bulk concentrations. The fate of precursors through gas-phase chemical reactions is followed by an efficient solver that determines their incremental reactivity, while the contributions to the secondary particulate species from their gaseous precursors is determined by assuming the thermodynamic equilibrium between the two phases. The paper details the new employed methodologies and illustrates the application of the apportionment scheme (based on 6 source sectors) to PM10 and O3, simulated on three domains of different dimensions in Italy, all sharing the same horizontal resolution and a common region (Lombardy). Spatial patterns of results show, on average, a relevant contribution of heating on PM10 concentration in January, with local hotspots dominated by road traffic. Contributions appear consistent in the three simulated domains, apart from the boundary conditions, influenced by the dimension of the domain. Hourly series of contributions to O3 concentrations in July at three selected sites show the dominance of boundary conditions, underlining the large scale of O3 formation. Finally, for PM10 components, the resulting sectorial contributions are compared with the impacts computed via the brute force method, showing that results are similar for elemental carbon and sulfate, while they are different for nitrate and ammonium, due to a different allocation of contributions and impacts between the methods. Each approach responds in principle to a different purpose, and their combined use provides possibly a wide set of information useful for addressing the different air quality management needs. [ABSTRACT FROM AUTHOR]

Simple Summary: The aim of the study was to evaluate the viral load in honey bee colonies after adopting two brood interruption techniques that are used to control varroa mite. We evaluated the efficacy of two integrated pest management (IPM) strategies, "Queen Caging" (QC) and "Trapping Comb" (TC) procedures, in conjunction with an oxalic acid treatment, to control varroa infestations and consequently lower the viral loads of Deformed Wing Virus (DWV) and Acute Bee Paralysis Virus (ABPV). Two distinct apiaries in Slovenia and Italy, each with a different climate, served as the research sites. In the experiment, the adult bee viral load, mite fall, colony strength, and acaricide efficiency were assessed. The study indicated that the TC approach might be more successful in lowering viral loads. Our results also showed that the acaricidal efficacy of the applied IPM protocols is high. Our study is the first attempt to assess viral infections in honey bees after IPM adoption. The results show the potential advantages of using targeted varroa treatments in combination with brood interruption strategies to manage honey bee viruses vectored by varroa mite. Honey bee viruses in combination with varroa mite are very damaging for honey bee colonies worldwide. There are no effective methods to control the viral load in honey bee colonies except regular and effective control of mites. Integrated Pest Management strategies are required to effectively control mites with veterinary medicines based on organic compounds. We evaluated the effect of two brood interruption techniques, queen caging (QC) and trapping comb (TC), followed by an oxalic acid treatment, on the mite fall, colony strength, and viral load of Deformed Wing Virus (DWV) and Acute Bee Paralysis Virus (ABPV). In this paper, we report the data obtained in two experimental sites, in Slovenia and Italy, in terms of the varroacide efficacy, colony strength, and viral load. The number of adult bees after the adoption of the two techniques showed similar decreasing trends in both locations. The viral load of Acute Bee Paralysis Virus did not show any significant reduction after 25 days, reported as the number of Real-Time PCR cycles needed to detect the virus. The viral load of DWV also did not show a significant reduction after 25 days. The acaricidal efficacy of the applied protocols was high in both experimental groups and in both apiaries. Both the queen caging and trapping comb techniques, followed by an oxalic acid treatment, can be considered effective varroa treatment strategies, but further studies should be carried out to evaluate the long-term effects on viral loads to plan the Integrated Pest Management strategy with the right timing before wintering. [ABSTRACT FROM AUTHOR]

This paper explores the dynamic relationship between the spiritual community of Damanhur and its founder, Oberto Airaudi. Scholars consider Airaudi to be an example of Weberian charismatic leadership that was sui generis; the community, however, experienced an early routinisation, which granted it longevity and stability. Doctrinal and social evolution instead suggests a change in this charismatic relationship over the years, which occurred in four phases. His charisma passed from the ability to perform occult practices (occultist), to ideate a syncretic cosmology centred on Damanhur (religious), eventually allowing him to become an "inspirer from the outside" (inspirational). The last phase explains the survival and partial routinisation of the charisma after his death (post mortem). The study primarily relies on the analysis of Damanhurian writings, with a particular focus on the initial ten years. It also incorporates qualitative data from fieldwork and ethnographic material available in the scientific literature. The analysis suggests that Damanhur did not start as a charismatic community but as a social experiment. The development of Airaudi's charisma, via a syncretic mythology based on a religious concept of memory, absorbed Damanhur's social dimension, shaping it according to a collective spiritual endeavour aimed at reconnecting human beings with their divine inner nature. [ABSTRACT FROM AUTHOR]

The number of data sources and models in the mobility and transport domain strongly proliferated in the last decade. Most formats have been created to enable specific and innovative applications. On the other hand, the available data models present a certain degree of complexity in terms of their integration and management due to partial overlaps, and in most cases, they could be exploited alternatively to implement the same smart and latest innovative solutions. This paper offers an overview of data models, standards and their relationships. A second contribution highlights any possible exploitation of data models for implementing operational processes for city transportation management and for the feeding of simulation and optimization processes that produce other data results in other data models. The final goal in most cases is the monitoring and control of city transport conditions, as well as the tactic and strategic planning of city infrastructure. This work was developed in the context of the CN MOST, a national center of sustainable mobility in Italy, and it is based on exploiting the Snap4City platform. [ABSTRACT FROM AUTHOR]

Tattoo-associated cutaneous reactions have become quite frequent given the increasing percentage of tattooed subjects globally and also in Italy. On the other hand, the increasing use of target therapy is showing the ability of these drugs to affect the immune system and also cause adverse tattoo-related reactions. In this paper, we report a case of a 42-year-old patient with stage-IIID melanoma undergoing treatment with Dabrafenib and Trametinib. The patient reported erythema, oedema and scaling in areas of the body containing a black tattoo, and, conversely, no signs and/or symptoms in areas with tattoos of a different color. Histopathological and immunohistochemical features indicated a lympho-histiocytic reaction with a granulomatous morphology, mainly distributed around the vessels and hair adnexa. By discussing the cases reported in the literature prior to ours, we concluded and provided the possible indications of the pathogenesis. [ABSTRACT FROM AUTHOR]

In this paper, we complete pioneering research that indicates the very low frequency (VLF) signal amplitude and phase noise reductions, and short-period wave excitations and attenuations as new potential earthquake precursors. We consider changes in the VLF signal broadcast in Italy by the ICV transmitter and recorded in Serbia that start a few tens of minutes before earthquakes. The sampling interval of the analyzed data is 0.1 s. The main objectives of this study are (1) to complete this research in the time and frequency domains during the periods of the four earthquakes analyzed in the previous studies, and (2) to define the parameters of the VLF signal amplitude and phase in both domains that should be further examined in statistical analyses of the aforementioned potential earthquake precursors. In the first part of this study, we analyze the ICV signal amplitude in the frequency domain during the period around three earthquakes that occurred in November 2010 near the considered signal propagation path. Here, we apply the Fourier transform to the relevant recorded data. In the second part, we compare characteristics of the signal amplitude and phase noise reductions in the time domain, and wave excitations and attenuations in the frequency domain. The results of these comparisons indicate the parameters that should be analyzed in subsequent studies to confirm the connection of the considered VLF signal changes with seismic activity before earthquakes, and potentially establish procedures for their detection are: (a) the start and end times of the noise reductions in the time domain and the excited/attenuated waves in the frequency domain, (b) the differences in the corresponding times, and (c) the wave periods of wave excitations of both the signal amplitude and phase. [ABSTRACT FROM AUTHOR]

This paper provides an assessment of a 24 GHz multiple-input multiple-output radar as a remote sensing tool to retrieve bathymetric maps in coastal areas. The reconstruction procedure considered here exploits the dispersion relation and has been previously employed to elaborate the data acquired via X-band marine radar. The estimation capabilities of the sensor are investigated firstly on synthetic radar data. With this aim, case studies referring to sea waves interacting with a constant and a spatially varying bathymetry are both considered. Finally, the reconstruction procedure is tested by processing real data recorded at Bagnoli Bay, Naples, South Italy. The preliminary results shown here confirm the potential of the radar sensor as a tool for sea wave monitoring. [ABSTRACT FROM AUTHOR]

The leading role of Italy in the cultivation of durum wheat stimulated intense breeding activities in the country from the beginning of the 20th century, much earlier than in any other country involved in durum wheat production. Older, genetically more heterogeneous landraces were replaced with new, highly productive, superior quality varieties, and this led to an inevitable reduction in the overall genetic diversity among new cultivars, which makes the genetic variability preserved in old cultivars particularly valuable and important. The aim of this paper was to assist future breeding programs by providing a detailed description of the history of durum wheat breeding in Italy and of the changes in yield, quality, and related traits that subsequently occurred, starting from the most diffuse landraces present between 1900 and 1920 up until the present day. The parallel evolution of breeding techniques, breeding goals, and agricultural systems in this period is also described, and some future breeding goals suggested. In the current context of climate change and of rapidly mutating pathogen populations, preserving the yield level through the continuous introduction of new cultivars by exploiting the reservoir of largely unused genetic variation stored in old cultivars and landraces could be as important as increasing grain yield and quality. [ABSTRACT FROM AUTHOR]

In the Northern Apennines, the Internal Ligurian Units are considered deformed and metamorphosed fragments of the Ligure-Piemontese oceanic basin. In this paper, we report on the temperature and pressure conditions of the metamorphic peak for four Internal Ligurian Units, estimated using different geothermometers and geobarometers based on the white mica and chlorite compositions. These minerals were formed during the D1 deformation phase in the pre-Oligocene. The results indicate that the Portello and Gottero units are both characterized by metamorphic conditions pertaining to low blueschists facies, while the Colli-Tavarone and Bracco-Val Graveglia Units show a lower metamorphic imprint that produces assemblages of prehnite-pumpellyite facies. The estimated geothermal gradient for the metamorphic peak achieved by the analyzed Internal Ligurian Units during the D1 phase is 7–15 °C/Km, which is indicative of deformation in a subduction setting. Under these conditions, the D1 phase developed in these units as a result of underplating at the base of the accretionary wedge during the closure of the Ligure-Piemontese basin. These data indicate a close geodynamic correlation among the Internal Ligurian Units and the ophiolite-bearing units of the Alps. [ABSTRACT FROM AUTHOR]

This document is a reply to a comment made by Inigo Navarro-Fernandez regarding a previous paper on a case of tinea corporis and onychomycosis caused by a terbinafine sensitive Trichophyton indotineae strain in Italy. The authors thank Navarro-Fernandez for their favorable comments and address the observations made about the nail lesions. They agree that the images only show onychomadesis, which is not typical of onychomycosis, but they explain that positive results from direct examination and culture led them to define the lesion as onychomycosis. The authors also state that without more precise anamnestic data, drawing conclusions is difficult. The authors declare no conflicts of interest. [Extracted from the article]