1. Association Between Child Sugary Drink Consumption and Serum Lipid Levels in Electronic Health Records.
- Author
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Iyer, Ankitha, Hsu, Fang-Chi, Bonnecaze, Alex, Skelton, Joseph A., Palakshappa, Deepak, and Lewis, Kristina H.
- Subjects
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BIOLOGICAL models , *HIGH density lipoproteins , *FRUIT juices , *FOOD consumption , *ADIPOSE tissues , *HYPERLIPIDEMIA , *RESEARCH funding , *LIPIDS , *MULTIPLE regression analysis , *MULTIVARIATE analysis , *DESCRIPTIVE statistics , *CARDIOVASCULAR diseases risk factors , *SERUM , *LOW density lipoproteins , *ODDS ratio , *ELECTRONIC health records , *FOOD habits , *TRIGLYCERIDES , *CONFIDENCE intervals , *FACTOR analysis , *BEVERAGES , *DIETARY cholesterol , *ADOLESCENCE , *CHILDREN - Abstract
Sugar-sweetened beverage (SSB) and fruit juice (FJ) consumption may promote lipid abnormalities in childhood. We examined the association between SSB/FJ intake and lipid levels using electronic health record data for 2816 adolescents. Multivariable logistic regression models treated clinical cutpoints for abnormal lipid levels (triglycerides [TG], high-density lipoprotein (HDL), low-density lipoprotein [LDL], and total cholesterol) as dependent variables. In models not adjusted for adiposity, elevated SSB and FJ consumption was associated with increased odds of having abnormally high TG (SSB: odds ratio [OR] = 1.28 (95% confidence interval [CI] = [1.07-1.52], P =.007); FJ: 1.35 ([1.09-1.69], P =.007)) and abnormally low HDL (SSB: 1.47 ([1.17-1.86], P =.001); FJ: 1.35 ([1.02-1.78], P =.03)). Adjusting for adiposity, a likely mediator of the relationship, attenuated these associations. These findings support the need for identifying unhealthy beverage consumption habits during childhood health care visits as a modifiable behavior associated with cardiometabolic risk. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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