Search

We reported a colorimetric paper-based device by integrating the modified acid RNA-cleaving DNAzymes (MaRCD-EC1) for highly sensitive (detection limit = 102 CFU mL−1), and rapid (within 30 min) detection of E. coli without amplification. This device exhibited a clinical sensitivity of 100% and a specificity of 100% in identifying E. coli-associated urinary tract infections (UTIs) using the clinical urine samples. [ABSTRACT FROM AUTHOR]

Gossypol, a phytotoxicant in cotton-seed oil, has been found to sensitize Tb(III)-luminescence in a supramolecular hydrogel. Based on this observation, a paper-based sensor has been developed to detect gossypol with a limit of detection (LOD) of 2.9 nM. This is the first report of water-based detection with the highest sensitivity involving turn-on time-gated luminescence. This method was also able to sense gossypol in commercial crude cotton-seed oil. [ABSTRACT FROM AUTHOR]

We report a series of structurally relevant copper phenanthroline complexes as pre-catalysts for highly selective electrocatalytic reduction of CO2 to C2 products using inexpensive carbon paper electrodes. The Cu complexes with non-substituted phenanthroline promote the production of ethylene with a high faradaic efficiency of 71.2%, while the one with pyridinium-functionalized ligands is more selective for ethanol. The C2 selectivity can be effectively tuned by increasing the number of coordinated phenanthrolines and remains high at a wide range of potentials. [ABSTRACT FROM AUTHOR]

We report a strategy that tunes the CO2 and proton concentrations near the electrode–electrolyte interface using surfactant modification with various amounts (0.05, 0.8, 1.6, and 3.2 mg) of hexadecyl trimethyl ammonium bromide (CTAB). The positively charged group of CTAB favors CO2 surface diffusion and inhibits excessive proton accumulation on Zn nanosheets on carbon paper. A CO faradaic efficiency of 95.6% and a total ampere density of −13.1 mA cm−2 were obtained over the optimal CTAB-modified Zn electrode at −1.1 V with stability over 12 hours. [ABSTRACT FROM AUTHOR]

This communication describes the development of polyvinyl chloride electrochemical system in which a paper layer loaded with reagents is inserted into the device, demonstrating a new concept of a paper card-like pad for a reagent-free and easy measurement of the target analyte in solution. This device detects glucose in artificial tears in the range of 0.2–2 mM with a detection limit of 50 μM by simply adding the artificial tears to the paper card-like pad. The novel configuration goes beyond the state of the art, widening the application range of paper in the design of smart analytical devices. [ABSTRACT FROM AUTHOR]

A novel, biodegradable substrate based, and cost-effective flexible electrochemical sensor was developed for the highly selective and sensitive detection of one of the major neurotransmitters, dopamine, which can be utilised as a disposable electrode for point-of-care diagnostic applications. The active material CuSnB decorated over cellulose paper exhibits good sensitivities of 3.92 μA μM−1 cm−2 with a limit of detection of 0.5 nM. Moreover, the flexible sensor demonstrated superior selectivity towards co-existing metabolites such as ascorbic acid, glucose, and uric acid, in addition to stability at various mechanical deformations. [ABSTRACT FROM AUTHOR]

A series of Ti-doped W18O49 samples were prepared using a convenient solvothermal route. Due to the synergistic effect of doped Ti and oxygen vacancies, the samples showed excellent visible-light photochromic properties. Their performances as light-printable rewritable paper and smart windows showed great application value and promotion value. [ABSTRACT FROM AUTHOR]

Detection and characterization of DNA damage plays a critical role in genotoxicity testing, drug screening, and environmental health. We developed a fully integrated origami paper-based analytical device (oPAD) for measuring DNA damage. This simple device allows on-paper cell lysis, DNA extraction, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) reaction and signal readout with simple operation steps, enabling rapid (within 30 min) and high throughput assessment of multiple DNA damages induced by exogenous chemical agents. [ABSTRACT FROM AUTHOR]

A tri-modal paper device based on flower-like CuSe was developed for monitoring Alzheimer's disease (AD)-related miRNA by integrating colorimetric, photothermal and surface-enhanced Raman scattering approaches. Significantly, false-negative signals at the early stage of AD were completely eliminated by using our presented tri-modal strategy. [ABSTRACT FROM AUTHOR]

We report a cyclic organosulfide synthesized via a condensation reaction. It can be cycled for 1000 times in half cells. Impressively, it can work with lithiated carbon paper as the anode in ether electrolyte in a full cell. This work shows the promising property of the organosulfide cathode in lithium batteries. [ABSTRACT FROM AUTHOR]

A well-designed support material between catalyst and substrate can always significantly enhance the performance of an electrode on water oxidation. In this work, a functional Ni and N-doped carbon layer (NNC) was designed on carbon paper (CP) via pyrolysis by using a controlled electrodeposited polyporphyrin as a precursor. Consequently, the fabricated NiFe-LDH/NNC/CP achieved a catalytic current density of 100 mA cm−2 at a small overpotential of 231 mV with a low Tafel slope of 26.0 mV dec−1, as well as high durability for more than 360 h. The insights are that N-doping reinforces the hydrophilicity and the catalyst binding capacity, while Ni-doping intensifies the conductivity. [ABSTRACT FROM AUTHOR]

A scalable, and cost-effective method was employed to prepare self-supported CuSn bimetallic catalyst on carbon paper. The obtained CuSn catalyst demonstrates high faradaic efficiency of CO around or above 90% at a broad potential range from −0.7 to −1.8 V vs. reversible hydrogen electrode, greatly surpassing Cu or Sn counterparts. [ABSTRACT FROM AUTHOR]

A novel non-enzymatic electrochemical sensor was constructed to achieve a highly selective and ultrasensitive detection of cholesterol to address the problems related to serious coronary heart disease. The NiVP/Pi-based sensor exhibited ultra-high sensitivity of 5510.18 μA μM−1 cm−2 and 36.8 μA μM−1 cm−2 for 1 nM to 10 μM and 100 μM to 10 mM of cholesterol, respectively, with an ultra-low detection limit of 1 aM, along with superior selectivity for cholesterol when exposed to various interferents such as ascorbic acid, glucose and uric acid. Also, a novel NiVP/Pi-based flexible sensor coated onto Whatman filter paper was developed and displayed superior sensitivity, even with a human blood serum sample at physiological pH. [ABSTRACT FROM AUTHOR]

Here, polyaniline (PANI) is reported loaded on carbon paper to modify the carbon paper-PANI-Pt electrode surface, tailoring the electrocatalytic capability towards the hydrogen evolution reaction and ethanol oxidation reaction. The reasons for the enhancement by the PANI layer are attributed to the hydrophilic electrode surface, uniform dispersion of Pt, and large electrochemical active surface. [ABSTRACT FROM AUTHOR]

The Biocatalysis Faraday Discussion was held from May 22 to 24, 2024, at the Royal Society of Chemistry in Burlington House, London. This meeting brought together established and early-career scientists, PhD students, and industrial researchers from around the world to engage in rigorous scientific dialogue on the latest advancements in biocatalysis. The conference featured a unique format, where speakers submitted full papers in advance and presented concise summaries, sparking in-depth discussions among participants. This report summarises the event, the presented results, and the concluding remarks, underscoring the collaborative and intellectually stimulating atmosphere of the Faraday Discussions. [ABSTRACT FROM AUTHOR]

In this paper, three neutral heterocycle-triazolotriazine compounds featuring multiple amino groups and nitro groups were designed and synthesized. Among them, compounds 2 and 6 exhibit high detonation performance (Dv = 8180 m s−1, 8650 m s−1; P = 26.40 GPa, 31.5 GPa), low sensitivities (IS > 40 J, FS > 360 N) and high thermal stabilities (Td = 319 °C, 320 °C) suggesting their potential as alternatives to the traditional thermal-stable explosive HNS (Dv = 7612 m s−1, P = 24.3 GPa, IS = 5 J, FS = 240 N; Td = 318 °C). Meanwhile, compound 4 displays excellent properties (Dv = 8810 m s−1, IS = 15 J, FS = 240 N, Td = 215 °C, ρ = 1.84 g cm−3) which is superior to traditional explosive RDX (Dv = 8795 m s−1, IS = 7.5 J, FS = 120 N, Td = 208 °C, ρ = 1.80 g cm−3) making it a promising candidate as a novel secondary explosive. This research not only advances the field of triazolotriazine-based energetic materials but also explores their potential applications as heat-resistant or high-energy explosives. [ABSTRACT FROM AUTHOR]

Nanowires and other high aspect ratio nanoparticles are building blocks to form network materials in formats such as films, sheets, fibres and electrodes that thus bridge the nano and macro scales. The assembly of nanowire network materials is enabled by a new floating catalyst chemical vapour deposition synthesis method that produces crystalline silicon nanowires (SiNW) on a scale of grams per day. Here, we produce SiNW dispersions in water by sonication through steric and electrostatic stabilisation of the negatively charged particles in basic pH or with cationic surfactants. Negative charge arises from the 1.3 nm-thin native oxide layer. Some permanent aggregates are found as a consequence of cross-links between the thin oxide at the surface of adjacent SiNWs. Removing them by centrifugation yields SiNW dispersions of 52 μg mL−1. Processing into macroscopic materials is demonstrated as transparent films and as freestanding sheets. In the sheets, the SiNWs are predominately aligned parallel to the sheet thickness, as a paper-like SiNW solid with tensile strength above 10 MPa, modulus above 1 GPa and toughness of 0.5 J g−1. [ABSTRACT FROM AUTHOR]

Reported herein is an ultra-sensitive turn-off fluorescence sensor for hydrogen peroxide based on its reaction with bimane 1. This reaction is highly efficient, resulting in a detection limit of 7.9 pM. It also maintains sensor efficacy when adsorbed on paper and enables both solution-state and vapor-phase detection. [ABSTRACT FROM AUTHOR]

Ultrathin nanosheets possess a distinctive structure characterized by an abundance of active sites fully accessible on their surface. Concurrently, their nanoscale thickness confers an extraordinarily high specific surface area and promising electronic properties. To date, numerous strategies have been devised for synthesizing precious metal nanosheets that exhibit excellent electrocatalytic performance. In this paper, recent progress in the controlled synthesis of two-dimensional, ultrathin nanosheets by a self-assembly mechanism using functional surfactants is reviewed. The aim is to highlight the key role of functional surfactants in the assembly and synthesis of two-dimensional ultrathin nanosheets, as well as to discuss in depth how to enhance their electrochemical properties, thereby expanding their potential applications in catalysis. We provide a detailed exploration of the mechanisms employed by several long-carbon chain surfactants commonly used in the synthesis of nanosheets. These surfactants exhibit robust electrostatic and hydrophobic effects, effectively confining the crystalline growth of metals along lamellar micelles. Moreover, we present an overview of the electrocatalytic performance demonstrated by the ultrathin nanosheets synthesized through this innovative pathway. Furthermore, it offers valuable insights that may pave the way for further exploration of more functional long-chain surfactants, leading to the synthesis of ultrathin nanosheets with significantly enhanced electrocatalytic performance. [ABSTRACT FROM AUTHOR]

This paper describes photoelectrochemical dehydrogenative cyclization of 2-arylbenzoic acid and 2-arylbenzamide in a PEC cell consisting of a mesoporous WO3 photoanode and Pt cathode. The cyclization reaction is effectively driven by this PEC system at room temperature with blue LED irradiation under external oxidant- and metal-free conditions, delivering a series of benzolactones and benzolactams in up to 95% isolated yields. Meanwhile, hydrogen is released as the only byproduct of this process. [ABSTRACT FROM AUTHOR]

In pursuit of global carbon neutrality, countries are intensifying their efforts to harness clean energy sources. Hydrogen emerges as a superior alternative to traditional fossil fuels and plays a crucial role in the global energy shift. Liquid Organic Hydrogen Carrier (LOHC) systems are lauded for their high hydrogen storage capacity, ease of handling, and safe and efficient transportation, positioning them as effective solutions for extensive hydrogen storage and international distribution. Nevertheless, the dehydrogenation of hydrogen-rich LOHCs is slow, requiring high temperatures and substantial energy inputs. Addressing these challenges by reducing energy demands and improving dehydrogenation rates is essential for advancing LOHC technology. This paper comprehensively examines various LOHC systems, focusing on the selection of carriers and dehydrogenation catalysts, and their dehydrogenation efficacy. It also highlights our recent contributions in photocatalytic LOHC and outlines future research directions to enhance LOHC technology. [ABSTRACT FROM AUTHOR]

Metal--organic frameworks (MOFs), an emerging class of highly ordered crystalline porous materials, possess structural tunability, high specific surface area, well-defined pores, and diverse pore environments and morphologies, making them suitable for various potential applications. Moreover, hydrogenbonded organic frameworks (HOFs), constructed from organic molecules with complementary hydrogen-bonding patterns, are rapidly evolving into a novel category of porous materials due to their facile mild preparation conditions, solution processability, easy regeneration capability, and excellent biocompatibility. These distinctive advantages have garnered significant attention across diverse fields. Considering the inherent binding affinity between MOFs and HOFs along with the fact that many MOF linkers can serve as building blocks for constructing HOFs, their combination holds promise in creating functional materials with enhanced performance. This feature paper provides an introduction to the interconversion between MOFs and HOFs followed by highlighting the emerging applications of MOF--HOF composites. Finally, we briefly discuss the current challenges associated with future perspectives on MOF--HOF composites. [ABSTRACT FROM AUTHOR]

Hybrid water electrolysis (HWE) is a promising pathway for the simultaneous production of high-value chemicals and clean H2 fuel. Unlike conventional electrochemical water splitting, which relies on the oxygen evolution reaction (OER), HWE involves the anodic oxidation reaction (AOR). The AORs facilitate the conversion of organic or inorganic compounds at the anode into valuable chemicals, while the cathode carries out the hydrogen evolution reaction (HER) to produce H2. Recent literature has witnessed a surge in papers investigating various AORs with organic and inorganic substrates using a series of transition metal-based catalysts. Over the past two decades, metal–organic frameworks (MOFs) have garnered significant attention for their exceptional performance in electrochemical water splitting. These catalysts possess distinct attributes such as highly porous architectures, customizable morphologies, open facets, high electrochemical surface areas, improved electron transport, and accessible catalytic sites. While MOFs have demonstrated efficiency in electrochemical water splitting, their application in hybrid water electrolysis has only recently been explored. In recent years, a series of articles have been published; yet there is no comprehensive article summarizing MOFs for hybrid water electrolysis. This article aims to fill this gap by delving into the recent progress in MOFs specifically tailored for hybrid water electrolysis. In this article, we systematically discuss the structure–property–performance relationships of various MOFs utilized in hybrid water electrolysis, supported by pioneering examples. We explore how the structure, morphology, and electronic properties of MOFs impact their performance in hybrid water electrolysis, with particular emphasis on value-added chemical generation, H2 production, potential improvement, conversion efficiency, selectivity, faradaic efficiency, and their potential for industrial-scale applications. Furthermore, we address future advancements and challenges in this field, providing insights into the prospects and challenges associated with the continued development and deployment of MOFs for hybrid water electrolysis. [ABSTRACT FROM AUTHOR]

Reductive elimination is a key step in Ni-catalysed cross-couplings, which is often considered to result in new covalent bonds. Due to the weak oxidizing ability of Ni(II) species, reductive eliminations from Ni(II) centers are challenging. A thorough mechanistic understanding of this process could inspire the rational design of Ni-catalysed coupling reactions. In this article, we give an overview of recent advances in the mechanistic study of reductive elimination from Ni(II) species achieved by our group. Three possible models for reductive elimination from Ni(II) species were investigated and discussed, including direct reductive elimination, electron density-controlled reductive elimination, and oxidation-induced reductive elimination. Notably, the direct reductive elimination from Ni(II) species often requires a high activation energy in some cases. In contrast, the electron density-controlled and oxidation-induced reductive elimination pathways can significantly enhance the driving force for reductive elimination, accelerating the formation of new covalent bonds. The intricate reaction mechanisms for each of these pathways are thoroughly discussed and systematically summarized in this paper. These computational studies showcase the characteristics of three models for reductive elimination from Ni(II) species, and we hope that it will spur the development of mechanistic studies of cross-coupling reactions. [ABSTRACT FROM AUTHOR]

This paper shows a novel oxidative functionalization of α-amino ketones to yield the corresponding α-ketoamides and α-acylimidates. The reaction proceeds via oxygen delivery from water/alcohols in conjunction with an electron acceptor and 4-dimethylaminopyridine (DMAP). Mechanistic study indicates that DMAP exhibits a dual function of nucleophilic catalysis and proton abstraction. [ABSTRACT FROM AUTHOR]

In this paper, we provide a novel electrode switch (ES) method to improve the stability of the alkaline electrolyzer toward water splitting. The voltage of the alkaline electrolyzer consisting of commercial Ni mesh electrodes utilizing the ES mode exhibits extreme stability because highly active Ni oxide(hydroxide) with oxygen defects is in situ formed during the hydrogen evolution reaction (HER) polarization process. [ABSTRACT FROM AUTHOR]

Membrane-based gas separation, characterized by a small footprint, low energy consumption and no pollution, has gained widespread attention as an environmentally friendly alternative to traditional gas separation. Metal–organic-frameworks (MOFs) are considered to be one of the most promising membrane-based gas separation materials because of their large specific surface area and high porosity. One of the hottest studies at the moment is how to utilize the characteristics of MOFs to prepare higher performance gas separation membranes. This paper provides a review of gas separation membranes used in recent years. Firstly, the synthesis methods of MOFs and MOF membranes are briefly introduced. Then, methods to improve the membrane properties of MOFs are described in detail, and include applications of lamellar MOFs, ionic liquid (IL) spin coating, functionalization of MOFs, defect engineering and mixed fillers. In addition, the challenges of MOF-based gas separation membranes are presented, including pore size, environmental disturbances, plasticization, interfacial compatibility, and so on. Finally, based on the current development status of the MOF membranes, the development prospects of MOF gas separation membranes are discussed. It is hoped to provide reliable and complete ideas for researchers to prepare high-performance gas separation membranes in the future. [ABSTRACT FROM AUTHOR]

Artificial intelligence (AI) offers transformative potential for chemical research through its ability to optimize reactions and processes, enhance energy efficiency, and reduce waste. AI-assisted chemical research (AI + chem) has become a global hotspot. To better understand the current research status of "AI + chem", this study conducted a scientific bibliometric investigation using CiteSpace. The web of science core collection was utilized to retrieve original articles related to "AI + chem" published from 2000 to 2024. The obtained data allowed for the visualization of the knowledge background, current research status, and latest knowledge structure of "AI + chem". The "AI + chem" has entered a stage of explosive growth, and the number of papers will maintain long-term high-speed growth. This article systematically analyzes the latest progress in "AI + chem" and objectively predicts future trends, including molecular design, reaction prediction, materials design, drug design, and quantum chemistry. The outcomes of this study will provide readers with a comprehensive understanding of the overall landscape of "AI + chem". [ABSTRACT FROM AUTHOR]

Benefiting from a high overpotential of the competitive hydrogen evolution reaction with a carbon paper cathode, the desired electrochemical reduction of imines was achieved with high faradaic efficiency by using H2O as a H-source. With this sustainable atom-economic strategy, a series of potentially versatile amines were obtained in medium-to-high yields (49–86%). [ABSTRACT FROM AUTHOR]

Electrocatalytic nitrate reduction reaction (NitRR) is an energy-saving and environmentally benign approach to synthesizing ammonia under ambient conditions. However, the development of noble metal-free catalysts with high activity and selectivity is still a significant challenge. In this study, uniformly dispersed amorphous CoBx nanoparticles supported on carbon paper were synthesized VIA a simple wet chemical reduction method. As an efficient nitrate reduction electrocatalyst, CoBx exhibited a maximum faradaic efficiency of 94.00 ± 1.67% and a yield rate of up to 0.787 ± 0.028 mmol h−1 cm−2 for ammonia production. The enhanced NitRR performance could be attributed to a partial electron transfer from B to Co, which is necessary for optimizing the adsorption energies of the reaction intermediates and facilitating electron transport. Thus, selective and cost-effective electroreduction of nitrates to ammonia can be achieved using CoBx nanoparticles. [ABSTRACT FROM AUTHOR]

The emergence of SARS-CoV-2 variants has further raised concerns about viral transmission. A fundamental understanding of the intermolecular interactions between the coronavirus and different surfaces is needed to address the transmission of SARS-CoV-2 through respiratory droplet-contaminated surfaces or fomites. The receptor-binding domain (RBD) of the spike protein is a key target for the adhesion of SARS-CoV-2 on the surface. To understand the effect of mutations on adhesion, atomic force microscopy-based single-molecule force spectroscopy (AFM-SMFS) was used to quantify the interactions between wild-type, Omicron, and XBB with several surfaces. The measurement revealed that RBD exhibits relatively higher forces on paper and gold surfaces, with the average force being 1.5 times greater compared to that on plastic surface. In addition, the force elevation on paper and gold surfaces for the variants can reach ∼28% relative to the wild type. These findings enhance our understanding of the nanomechanical interactions of the virus on common surfaces. [ABSTRACT FROM AUTHOR]

Ionic liquids (ILs) have emerged as a new class of materials, displaying a unique capability to self-assemble into micelles, liposomes, liquid crystals, and microemulsions. Despite evident interest, advancements in the controlled formation of amphiphilic ILs remain in the early stages. Taking inspiration from nature, we introduced the concept of lipid-like (or lipid-inspired) ILs more than a decade ago, aiming to create very low-melting, highly lipophilic ILs that are potentially bio-innocuous – a combination of attributes that is frequently antithetical but highly desirable from several application-specific standpoints. Lipid-like ILs are a subclass of functional organic liquid salts that include a range of lipidic side chains such as saturated, unsaturated, linear, branched, and thioether while retaining melting points below room temperature. It was observed in several homologous series of [Cnmim] ILs that elongation of N-appended alkyl chains to greater than seven carbons leads to a substantial increase in melting point (Tm) – which is the most characteristic feature of ILs. Accordingly, it is challenging to develop ILs with low Tm values while preserving their hydrophobicity and self-organizing properties. We found that two alternative Tm depressive approaches are useful. One of these is the replacement of the double bonds with thioether moieties in the alkyl chains, as detailed in several published papers detailing the chemistry of these ILs. Employing thiol–ene and thiol–yne click reactions is a facile, robust, and orthogonal method to overcome the challenges associated with the synthesis of alkyl thioether-functionalized ILs. The second approach involves replacing the double bonds with the cisoid cyclopropyl motif, mimicking the strategy used by certain organisms to modulate cell membrane fluidity. This discovery has the potential to greatly impact the utilization of lipid-like ILs in various applications, including gene delivery, lubricants, heat transfer fluids, and haloalkane separations, among others. This feature article presents a concise, historical overview, highlighting key findings from our work while offering speculation about the future trajectory of this de novo class of soft organic-ion materials. [ABSTRACT FROM AUTHOR]

The advent of two-dimensional nanomaterials, a revolutionary class of materials, is marked by their atomic-scale thickness, superior aspect ratios, robust mechanical attributes, and exceptional chemical stability. These materials, producible on a large scale, are emerging as the forefront candidates in the domain of membrane-based gas separation. The concept of defect engineering in 2D nanomaterials has introduced a novel approach in their application for membrane separation, offering an effective technique to augment the performance of these membranes. Nonetheless, the development of customized microstructures in gas separation membranes via defect engineering remains nascent. Hence, this review is designed to serve as a comprehensive guide for the application of defect engineering in 2D nanomaterial-based membranes. It delves into the most recent developments in this field, encompassing the synthesis methodologies of defective 2D nanomaterials and the mechanisms underlying gas transport. Special emphasis is placed on the utilization of defect-engineered 2D nanomaterial-based membranes in gas capture applications. Furthermore, the paper encapsulates the burgeoning challenges and prospective advancements in this area. In essence, defect engineering emerges as a promising avenue for enhancing the efficacy of 2D nanomaterial-based membranes in gas separation, offering significant potential for advancements in membrane-based gas separation technologies. [ABSTRACT FROM AUTHOR]

Experimental data supporting the claim that a carbonaceous sulfur hydride (CSH) under pressure is a high temperature superconductor were presented. Here we report results of a mathematical analysis that indicates that with probability larger than 1–10−338 some of those data were not measured in a laboratory, contrary to what the papers claim. This finding undermines confidence in the claim that any of the experimental evidence reported in those papers reflects the properties of real physical samples of CSH. [ABSTRACT FROM AUTHOR]

We designed a paper-based analytical device by integrating horseradish peroxidase (HRP)-encapsulated 3D DNA for visual detection of alkaline phosphatase (ALP). This device allows on-paper sample pre-treatment, target recognition and signal readout, enabling simple (without additional pre-treatment of blood samples) and rapid (within 23 min) determination of ALP in clinical samples. [ABSTRACT FROM AUTHOR]

DNA nanostructures are easy to design and construct, have good biocompatibility, and show great potential in biosensing and drug delivery. Numerous distinctive and versatile DNA nanostructures have been developed and explored for biomedical applications. In addition to DNA nanostructures that are completely assembled from DNA, composite DNA nanostructures obtained by combining DNA with other organic or inorganic materials are also widely used in related research. The CRISPR/Cas system has attracted great attention as a powerful gene editing technology and is also widely used in biomedical diagnosis. Many researchers are committed to exploring new possibilities by combining DNA nanostructures with CRISPR/Cas systems. These explorations provide support for the development of new detection methods and cargo delivery pathways, provide inspiration for improving relevant gene editing platforms, and further expand the application scope of DNA nanostructures and CRISPR/Cas systems. This paper mainly reviews the design principles and biomedical applications of CRISPR/Cas combined with DNA nanostructures based on the types of DNA nanostructures. Finally, the application status, challenges and development prospects of CRISPR/Cas combined with DNA nanostructures in detection and delivery are summarized. It is expected that this review will enable researchers to better understand the current state of the field and provide insights into the application of CRISPR/Cas systems and the development of DNA nanostructures. [ABSTRACT FROM AUTHOR]

The direct conversion of methane to hydrogen and high-value hydrocarbons under mild conditions is an ideal, carbon-neutral method for utilizing natural gas resources. Compared with traditional high-temperature thermal catalytic methods, using clean light energy to activate inert C–H bonds in methane can not only significantly reduce the reaction temperature and avoid catalyst deactivation, but also surpass the limitations of thermodynamic equilibrium and provide new reaction pathways. This paper provides a comprehensive review of developments in the field of photocatalytic non-oxidative conversion of methane (PNOCM), while also highlighting our contributions, particularly focusing on catalyst design, product selectivity, and the underlying photophysical and chemical mechanisms. The challenges and potential solutions are also evaluated. The goal of this feature article is to establish a foundational understanding and stimulate further research in this emerging area. [ABSTRACT FROM AUTHOR]

The electrocatalytic nitrogen reduction reaction (eNRR) under ambient conditions is deemed a promising alternative for NH3 synthesis. In this paper, an FeP–Fe3O4 nanocomposite electrocatalyst was prepared by phosphating annealing using Fe2O3 as a precursor, and the resulting FeP–Fe3O4 exhibited excellent N2-to-NH3-producing activity over a wide potential window. The highest faradaic efficiency of FeP–Fe3O4 is 11.02% at −0.1 V vs. reversible hydrogen electrode (RHE), and the maximum NH3 yield reaches 12.73 μg h−1 mgcat−1, comparable to or exceeding the reported values in this field. Furthermore, the FeP–Fe3O4 nanocomposite electrocatalyst presents high electrochemical stability, selectivity, and durability. [ABSTRACT FROM AUTHOR]

Nanoarchitectonics, as a post-nanotechnology concept, constructs functional materials and structures using nanounits of atoms, molecules, and nanomaterials as materials. With the concept of nanoarchitectonics, asymmetric structures, and hierarchical organization, rather than mere assembly and organization of structures, can be produced, where rational physical and chemical communications will lead to the development of more advanced functional materials. Layer-by-layer assembly can be a powerful tool for this purpose, as exemplified in this feature paper. This feature article explores the possibility of constructing advanced functional systems based on recent examples of layer-by-layer assembly. We will illustrate both the development of more basic methods and more advanced nanoarchitectonics systems aiming towards practical applications. Specifically, the following sections will provide examples of (i) advancement in basics and methods, (ii) physico-chemical aspects and applications, (iii) bio-chemical aspects and applications, and (iv) bio-medical applications. It can be concluded that materials nanoarchitectonics based on layer-by-layer assembly is a useful method for assembling asymmetric structures and hierarchical organization, and is a powerful technique for developing functions through physical and chemical communication. [ABSTRACT FROM AUTHOR]

Given the rising lithium-ion battery retirement trend, there is a pressing need for a sustainable, cost-effective, versatile, and industrially viable positive active powder reprocessing method. The current treatment methods require significant amounts of acids, reducing agents, and other additives, resulting in increased treatment expenses and detrimental environmental consequences. This paper proposes a synergistic redox strategy, based on thermodynamic calculations of potential self-promoting reactions in mixed LFP/NCM systems, for the recovery of spent LFP and NCM batteries without the need for additional agents in a milder acidic atmosphere. In this cooperative redox strategy, the spontaneous extraction and oxidation of Fe2+ to Fe3+ took place within the acidic solution atmosphere encapsulating LFP. Simultaneously, NCM underwent further reduction, yielding Ni2+ and Fe2+, thereby enabling the proficient dissolution and segregation of lithium and transition metal ions. The leaching rate of lithium, nickel, cobalt and manganese was close to 100% when the reaction was carried out at 20 °C for 40 min. The final raw material was reprepared into a battery with a capacity of 168.8 mA h g−1 at 1C, and the cycle retention rate was 76.78% after 300 cycles. Regenerating FPO into LFP cathode material achieves closed-loop recycling of all elements and generates 12% higher profits compared to separate processes. Our method proposes a zero-additive battery recycling process and successfully explains the intrinsic redox process. [ABSTRACT FROM AUTHOR]

The current review describes different annulation strategies reported with electrophilic benzannulated heterocycles for accessing heteroacenes. For the past two decades, the chemistry of electrophilic benzannulated heterocycles was extensively investigated, and several dipolar cycloadditions, metal and organo-catalyzed transformations were introduced for the generation of fused heterocycles. In this review, we have collected all the reports where the annulation of electrophilic benzannulated heterocycles results in a fully aromatic system, viz. heteroacenes with tri-, tetra-, and pentacyclic rings. We reviewed every paper on the synthesis of fused heterocycles that was accessible and categorized the review into several parts based on the electrophilic benzannulated heterocycle used in the heteroacene synthesis such as electrophilic indole, electrophilic benzothiophene, and so forth. The generality and mechanistic postulates of each methodology are highlighted. In addition, we have also tried to feature the advantages or shortcomings of each method and have mentioned the possible applications of these methodologies for accessing heteroacenes for material applications. [ABSTRACT FROM AUTHOR]

In this paper, benzo-fused cyclic carbonates were designed and synthesized as a new type of precursor of π-allylpalladium zwitterionic intermediates, and were applied in Pd-catalyzed diastereo- and enantioselective (4+3) cycloaddition with C,N-cyclic azomethine imines, leading to various biologically important 1,3,4-benzoxadiazepine derivatives in 43–99% yields with 6 : 1 to >20 : 1 dr and up to 95% ee. [ABSTRACT FROM AUTHOR]

Homopurine strands are known to form antiparallel triplexes stabilized by G*G and A*A Hoogsteen pairs, which have two hydrogen bonds. But there has been no report on the parallel triplex formation of homopurine involving both adenosine and guanosine to the duplex. In this paper, we first report parallel triplex formation between a homopurine serinol nucleic acid (SNA) strand and an RNA/SNA duplex. Melting profiles revealed that the parallel SNA:RNA*SNA triplex was remarkably stable, even though the A*A pair has a single hydrogen bond. An L -acyclic threoninol nucleic acid (L -aTNA) homopurine strand also formed a stable parallel triplex with an L -aTNA/RNA duplex. [ABSTRACT FROM AUTHOR]

Polyimide covalent organic frameworks (PI-COFs) are outstanding functional materials for electrochemical energy conversion and storage owing to their integrated advantages of the high electroactive feature of polyimides and the periodic porous structure of COFs. Nevertheless, only anhydride monomers with C2 symmetry are generally used, and limited selectivity of electron-deficient monomers has become a major obstacle in the development of materials. The introduction of polycyclic aromatic hydrocarbons (PAHs) is a very effective method to regulate the structure–activity relationship of PI-COFs due to their excellent stability and electrical properties. Over the past two years, various star-shaped electron-deficient PAH building blocks possessing different compositions and topologies have been successfully fabricated, greatly improving the monomer selectivity and electrochemical performances of PI-COFs. This paper systematically summarizes the recent highlights in PI-COFs based on these building blocks. Firstly, the preparation of anhydride (or phthalic acid) monomers and PI-COFs related to different star-shaped PAHs is presented. Secondly, the applications of these PI-COFs in energy conversion and storage and the corresponding factors influencing their performance are discussed in detail. Finally, the future development of this meaningful field is briefly proposed. [ABSTRACT FROM AUTHOR]

In this paper, the synthesis of a novel tetra-phenol π-extended dihydrophenazine is reported. The obtained derivative presents marked reducing properties in the excited state and was exploited as an organo-photocatalyst in dehalogenation and C–C bond formation reactions. These results underline the great potential of functionalized π-extended dihydrophenazines as organo-photocatalysts. [ABSTRACT FROM AUTHOR]

Ionic transition-metal complexes (iTMCs) with rich excited-state properties and excellent optical properties have attracted considerable attention from both the scientific and industrial community in recent decades. Controlling their photophysical properties is very important for realizing a diverse range of optoelectronic applications. Generally, the optical property modulation of iTMCs is achieved by covalent structural modification of their ligand skeleton. In this feature article, we highlight the full potential of the regulation of the optical properties of iTMCs through changing various counterions, which is demonstrated to be a facile and convenient method. This paper lists different counterions that can be used to tune the emission wavelengths, emission lifetimes, and response behaviors of iTMCs. This paper also summarizes the advances towards multi-level information encryption and high-level anti-counterfeiting applications. Moreover, the recent challenges relating to this topic are examined alongside various future directions. We anticipate that the research provided in this paper will assist in directing future analyses based on the regulation of the photophysical properties of iTMCs in a facile, reproducible, and convenient way. [ABSTRACT FROM AUTHOR]

Designing counter electrodes (CEs) with high efficiency and understanding the mechanism of dye-sensitized solar cells (DSSCs) are still challenges. In this paper, we synthesized K-doped molybdenum disulfide (K-MoS2) with few layers and it has a great enhancement effect on the electrocatalytic activity compared to pure MoS2 CE and reference Pt CE. A dual electron-path model is proposed to explain the mechanism, which is supported by first-principles calculations. When an electron in MoS2 is transferred to the triiodide, the K atoms can act as an electron reservoir to provide another electron in a short time to improve the catalytic activity. So the proposed dual-electron effect in this paper is helpful to understand the charge transfer mechanism on the interfaces of these CEs and may be crucial for obtaining high photoelectric efficiencies in DSSCs. [ABSTRACT FROM AUTHOR]

As an emerging functional material, liquid metal–hydrogel composites exhibit excellent biosafety, high electrical conductivity, tunable mechanical properties and good adhesion, thus providing a unique platform for a wide range of flexible electronics applications such as wearable devices, medical devices, actuators, and energy conversion devices. Through different composite methods, liquid metals can be integrated into hydrogel matrices to form multifunctional composite material systems, which further expands the application range of hydrogels. In this paper, we provide a brief overview of the two materials: hydrogels and liquid metals, and discuss the synthesis method of liquid metal–hydrogel composites, focusing on the improvement of the performance of hydrogel materials by liquid metals. In addition, we summarize the research progress of liquid metal–hydrogel composites in the field of flexible electronics, pointing out the current challenges and future prospects of this material. [ABSTRACT FROM AUTHOR]

This paper describes the design and synthesis of a conjugate, which is composed of a percarboxylated water-soluble pillar[6]arene and three fluorescent pyrene chromophores on alternating methylene bridges. The optical characteristics are investigated. This conjugate is capable of encapsulating polycationic guest spermine, which results in an enhancement in the fluorescence intensity of pyrene. This host–pyrene conjugate is used for direct sensing of spermine, which shows selectivity towards a variety of biological analytes. The detection of spermine is demonstrated in live cells. [ABSTRACT FROM AUTHOR]

Phenolic compounds are ubiquitous in nature because of their unique physical and chemical properties and wide applications, which have received extensive research attention. Phenolic compounds represented by tannic acid (TA) play an important role at the nanoscale. TA with a polyphenol hydroxyl structure can chemically react with organic or inorganic materials, among which metal–phenolic networks (MPNs) formed by coordination with metal ions and polyphenol derivatives formed by interactions with organic matter, exhibit specific properties and functions, and play key roles in photo(electro)catalysis. In this paper, we first introduce the fundamental properties of TA, then summarize the factors influencing the properties of MPNs and structural transformation of polyphenol-derived materials. Subsequently, the functions of MPNs and polyphenol derivatives in photo(electro)catalysis reactions are summarized, encompassing improving interfacial charge carrier separation, accelerating surface reaction kinetics, and enhancing light absorption. Finally, this article provides a comprehensive overview of the challenges and outlook associated with MPNs. Additionally, it presents novel insights into their stability, mechanistic analysis, synthesis, and applications in photo(electro)catalysis. [ABSTRACT FROM AUTHOR]