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The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Recent Advances in iPSC-derived Cell Types, Volume 4 addresses how different cell types can be derived from induced pluripotent stem cells.Somatic cells can be reprogrammed into Induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to form different cell types which can be used in cell therapy as well as to model several diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cellular populations, tissues and organs using state-of-art techniques. This volume will cover what we know so far about the use of iPSCs to derive different cell types, such as: erythroid cells, mucosal-associated invariant T cells, megakaryocytes, cerebral cortical neurons, inner ear cell types, airway epithelial cells, male germ cells, trophoblasts, cardiomyocytes, ßpancreatic cells, and more. The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation; and is contributed by world-renowned authors in the field. - Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine and therapeutics - Covers the following cell types derived from iPSCs: erythroid cells, mucosal-associated invariant T cells, megakaryocytes, cerebral cortical neurons, inner ear cell types, airway epithelial cells, male germ cells, trophoblasts, cardiomyocytes, ßpancreatic cells, and more - Contributions from stem cell leaders around the world

Regenerative therapy has rapidly developed as one of the most promising treatments for patients suffering from severe heart failure. Autologous bone marrow-derived cells and cardiac stem cells have been clinically applied for cell injection therapy for heart failure. As a next-generation therapy, tissue-engineered myocardial-patch transplantation h

Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human - Organ Systems - Molecular Pathology/Basic Mechanisms of Diseases - Animal Models/Other Model Systems - Experimental Pathology - Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. - Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting - Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of'Normal'and'Disease'anatomy and histology images - Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions