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Pediatric Surgery provides an authoritative, up-to-date and comprehensive analysis of current practice in the field. It is divided into three topical volumes, with a total of seven sections focusing on general principles, newborn surgery, general pediatric surgery, tumor surgery, trauma, transplantation, and pediatric urology surgery. Detailed descriptions of surgical techniques and pre- and postoperative management are provided by experts from various parts of the world.The result is an international reference on the surgical management of both common and rare diseases of infants and children that will be an ideal source of information and guidance for pediatric surgeons, pediatric urologists, neonatologists, pediatricians, and all those seeking more detailed information on surgical conditions in children. The three topical volumes are as follows:General Principles and Newborn SurgeryGeneral Pediatric Surgery, Tumors, Trauma andTransplantationPediatric Urology

This volume contains ten chapters, each of which describes a recent advancement in health and disease. Chapter One aims to discuss various molecules proposed as potential disease biomarkers of biliary atresia in the recent past along with their strengths and weaknesses. Chapter Two provides an up-to-date review of the main metabolic pathways involved with the beneficial effects attributed to HIIT in the white adipose tissue, brown adipose tissue, liver, heart, and pancreas of rodent models. Chapter Three examines nine cases of motor neuron disease associated with frontotemporal dementia. Chapter Four explores the functional diversity of the endoplasmic reticulum, the largest endo-membrane organelle that exerts a central role in cellular functions. Chapter Five reviews the evolution of COVID-19, caused by the virus SARS-CoV2, as a threat to the health care system worldwide. Chapter Six deals with therapeutic apheresis and/or monoclonal antibodies in the treatment of hemolytic uremic syndrome in view of pathophysiologic aspects. Chapter Seven deals with the concept of health literacy in the digital era. Chapter Eight reviews the clinical and pathologic features of sarcoid myopathy. Chapter Nine examines the outbreaks of yersiniosis during the years 2010-2020, the pathogenicity of Y. enterocolitica as well as the clinical symptoms of the infection in humans. Lastly, Chapter Ten provides a clinicopathologic review of focal myositis, a rare disorder first described in 1977 by Heffner and colleagues.

This approachable guide meets health and social sciences scholars at their level--either as a reference text or as an enchanting but practical read--and walks them through each stage of their academic publishing journey. Drawing on a wealth of examples from his own experience mentoring others and publishing 300+ articles, Dr. Schwartz engages early, mid-, and senior-level professionals as well as graduate students and postdoctoral fellows alike, to demystify each stage of the writing and publishing process. Employing a reader-friendly, accessible voice, Dr. Schwartz's style captivates readers across disciplines, with a refreshing, can-do perspective. Before diving in, the author relates his own personal story in scholarly publishing, inviting all academics to unlock the high-impact writer within. The next set of chapters tackle the nuts and bolts of the academic publishing process, with basics such as topic selection, data analysis for publication, writing preparation, drafting and editing manuscripts, and journals submissions. The book advances into more innovative topics that can be simultaneously intimidating and rewarding, including recruiting and collaborating with coauthors, developing a network, navigating the peer review process, publishing nonempirical papers, getting creative with rejected manuscripts, foraying into Open Access and fee-based publishing, and even how to publish a book or book chapter. Designed as a digital mentor, The Savvy Academic is the ultimate tool for students, fellows, and scholarly professionals of a broad range of experiences in the health and social sciences who are looking to launch or elevate their scholarly publication career.

To promote effectiveness and minimize possible toxicity, the dosage of certain medications must be adjusted in persons with compromised kidney function. Failure to enjoin appropriate dosage adjustments in patients with abnormal or rapidly changing kidney function continues to lead to reports of drug toxicity involving a broad array of renally eliminated medications.This updated edition captures nearly 200 new drugs that have been approved by the FDA since the initial publication of Renal Pharmacotherapy. It also covers new evidence that has emerged regarding the need to adjust dosage of certain older medications that are eliminated by the kidneys. Additionally, it presents new data that are being continuously derived in the areas of patient-specific dose individualization for drugs of all types.Comprehensive, convenient, and evidence-based, this reference closes several identified knowledge gaps and will continue to be the leading collection of dosage recommendations for patients with compromised kidney function.

This sixth edition of the Oxford Textbook of Palliative Medicine takes us now into the third decade for this definitive award-winning textbook. It has been rigorously updated to offer a truly global perspective, highlighting the best current evidence-based practices, and collective wisdom from more than 200 experts around the world. This leading textbook covers all the new and emerging topics, updated and restructured to reflect major developments in the increasingly widespread acceptance of palliative medicine as a fundamental public health need. The sixth edition includes new sections devoted to family and caregiver issues, cardio-respiratory symptoms and disorders, and genitourinary symptoms and disorders. In addition, the multi-disciplinary nature of palliative care is emphasized throughout the textbook, covering areas from ethical and communication issues, the treatment of symptoms, and the management of pain. The Oxford Textbook of Palliative Medicine is a truly comprehensive text. No hospital, hospice, palliative care service, or medical library should be without this essential source of information. This sixth edition of the Oxford Textbook of Palliative Medicine is dedicated to the memory of Professor Kenneth Fearon husband of Professor Marie Fallon and a surgeon who became a world leader in the research and management of anorexia and cachexia. He modeled a work-life balance that is so critical in our field, with devotion to both his patients and his family.

Neurodegeneration is a key feature of several diseases that are referred to as neurodegenerative diseases. The process of neurodegeneration is not well-understood so the diseases that stem from it have, as yet, no cures. As such, studying the effects of these disorders can provide insight into the treatment, prevention, and future opportunities and challenges in this growing field. The Handbook of Research on Critical Examinations of Neurodegenerative Disorders is a critical scholarly resource that provides an extensive explanation of various neurodegenerative disorders based on existing studies to clarify etiology, pathological mechanisms, diagnosis, therapeutic interventions, as well as current status and future opportunities and challenges. Featuring coverage on a broad range of topics such as dementia, mitochondrial dysfunction, and risk factors, this book is geared towards neurobiologists, neuropsychologists, neurophysiologists, neuropathologists, medical professionals, academicians, and researchers seeking research on the complexity of neurodegenerative disorders.

The Manual of Hypertension of the European Society of Hypertension reflects emerging concepts that have the potential to impact diagnostic and therapeutic approaches to hypertension. Updating all material, this new edition also delves into a number of areas that have received heightened interest in recent years or have become a matter of debate due to the controversial interpretation of the available data.FEATURES Reflects emerging concepts impacting diagnostic and therapeutic approaches Explores background, history, epidemiology, and risk factors Describes pharmacological, nonpharmacological, and medical treatments Examines hypertension in special populations and treatment

Trauma in older people aged over 65 is a rapidly growing field within orthopaedics. Up to two thirds of fractures occur as a result of a fall and about one third of all fractures occur in the over-65 population. The aim of this comprehensive new text is to present the epidemiology and management of all musculoskeletal trauma that occurs in the elderly. The book deals with the assessment and treatment of medical comorbidities, complications, and the role of orthogeriatric care.The focus of the book is on the practical management of fractures although soft tissue injuries and dislocations are also discussed. Reflecting the multidisciplinary nature of the field, contributors are drawn from orthopaedics and orthogeriatrics on both sides of the Atlantic. The book is intended for all surgeons and physicians involved in the treatment of trauma in the elderly, and it will be relevant to trainees and as well as experienced practitioners.

Drawing on key concepts in sociology and management, this history describes a remarkable institute that has elevated medical research and worked out solutions to the troubling practices of commercial pharmaceutical research. Good Pharma is the answer to Goldacre's Bad Pharma: ethical research without commercial distortions.

This book continues as volume 7 of a multi-compendium on Edible Medicinal and Non-Medicinal Plants. It covers plant species with edible flowers from families Acanthaceae to Facaceae in a tabular form and seventy five selected species from Amaryllidaceae, Apocynaceae, Asclepiadaceae, Asparagaceae, Asteraceae, Balsaminaceae, Begoniaceae, Bignoniaceae, Brassicaceae, Cactaceae, Calophyllaceae, Caprifoliaceae, Caryophyllaceae, Combretaceae, Convolvulaceae, Costaceae, Doryanthaceae and Fabaceae in detail. This work will be of significant interest to scientists, medical practitioners, pharmacologists, ethnobotanists, horticulturists, food nutritionists, botanists, agriculturists, conservationists, lecturers, students and the general public. Topics covered include: taxonomy; common/English and vernacular names; origin and distribution; agroecology; edible plant parts and uses; botany; nutritive/pharmacological properties, medicinal uses, nonedible uses; and selected references.

Hypertension has become a major public health hazard not only in industrialized nations, but also in emerging economies. Early detection combined with effective treatment is imperative to reduce the risk of patients developing premature cardiovascular disease and accelerated atherosclerosis. A clear, concise resource, Hypertension: A Clinical Guide

Despite recent advances in healthcare, hypertension is a leading cause of death and remains a disease burden worldwide. Now in its second edition, the Manual of Hypertension of the European Society of Hypertension reflects emerging concepts that have the potential to impact diagnostic and therapeutic approaches to this condition. Updating all mater

La nefrología constituye una parte importante del quehacer del internista, quien suele participar en el estudio y el manejo de las enfermedades del riñón, órgano que además de presentar enfermedades propias suele ser blanco de la historia natural de enfermedades crónicas que lo dañan, provocan pérdida de las nefronas y deterioro de la función renal. Las principales causas de enfermedad renal terminal en México son la diabetes mellitus y la hipertensión arterial. Por lo anterior, el internista debe conocer la fisiología renal, así como la patología del órgano, los mecanismos de lesión renal, cómo se manifiesta clínicamente su deterioro y cómo manejar al paciente con enfermedad renal, ya sea intrínseca o secundaria. En los hospitales generales en México el internista suele ser quien maneja a estos pacientes; por esta razón el libro va dirigido principalmente a ellos; sin embargo, esta obra, que desarrolla cada tema en forma sencilla y fluida, será de gran utilidad también para los médicos generales o de otras especialidades que en su práctica diaria atienden pacientes nefrológicos. Como consecuencia de la necesidad de actualización que los internistas tienen en el área, y del compromiso de estos especialistas de brindar una atención médica de calidad a la sociedad, los editores ponen a disposición de la comunidad médica este volumen de Controversias en nefrología, escrito por un grupo de destacados especialistas, expertos cada uno de ellos en los temas que desarrollaron, esperando que atienda exitosamente las necesidades de conocimiento en los temas desarrollados para una mejor atención a nuestros pacientes. Los temas revisados incluyen la fisiopatología de las distintas nefropatías, cómo realizar la evaluación de estos pacientes, el manejo integral de los enfermos de acuerdo con los distintos padecimientos y la prevención del daño renal; aunque la obra va dirigida al médico internista, la forma en que fueron abordados los temas permite que sea de utilidad también para profesionistas de otras especialidades y para el médico general que se enfrenta al manejo del enfermo nefrópata.

Nie mehr sprachlos in Rio, Madrid oder Lissabon!Mit diesem Wörterbuch ist Kommunikation einfach. Es umfasst den kompletten medizinischen Grundwortschatz, den Sie bei Ihrem Auslandsaufenthalt als Arzt, Medizinstudent oder medizinische Fachkraft benötigen.- Rund 4300 medizinische Fachbegriffe in Deutsch-Spanisch-Portugiesisch- Redewendungen für das Patientengespräch und den Arbeitsalltag- Berücksichtigt zusätzlich das brasilianische Portugiesisch

In unveränderter 3. Auflage ist das bewährte Medizinische Wörterbuch Deutsch - Spanisch – Portugiesisch wieder verfügbar. Es enthält für jede Sprache über 4300 Begriffe und ihre Übersetzungen in die beiden anderen Sprachen. Der ganze Grundwortschatz medizinischer Fachbegriffe ist enthalten, aber auch umgangssprachliche Begriffe sind berücksichtigt. Auch die Besonderheiten des brasilianischen Portugiesisch sind aufgenommen. Für Ärzte, Fachberufe im Gesundheitswesen und Medizinstudenten, aber auch für Übersetzer medizinischer Texte eine unerlässliche Hilfe!

Your awareness of uncommon diseases and possible complications is vital to successful anesthetic patient management. Anesthesia and Uncommon Diseases, 6th Edition, brings you up to date with new information on less commonly seen diseases and conditions, including the latest evidence and management guidelines. This unique medical reference book is essential for a complete understanding of today's best options and potential difficulties in anesthesia. - Improve your ability to successfully manage every patient, including those with rare diseases or conditions. - Avoid complications with unique coverage of an important aspect of anesthetic management. - Access the complete contents and illustrations online at www.expertconsult.com - fully searchable! - Stay current with all-new chapters on adult congenital heart disease, rheumatic diseases, and the cancer patient, plus many more revisions throughout. - Get outstanding visual guidance with hundreds of illustrations, now in full color.

Übergewicht und Adipositas nehmen weltweit zu: In Deutschland ist die Mehrzahl der Erwachsenen übergewichtig oder adipös, unter den Kindern und Jugendlichen ist es bereits fast ein Viertel. Adipositas bedeutet für die Betroffenen gravierende gesundheitliche Risiken und Probleme, die im Rahmen einer Notfall- oder Krankenhausbehandlung lebensbedrohlich werden können. Die Vielzahl der Begleiterkrankungen und der pathophysiologischen Veränderungen des Atemapparates und des Herz-Kreislaufsystems führen zu einem deutlich erhöhten Risiko perioperativer Komplikationen. Zur Beherrschung dieser Risiken sind spezielle Abläufe und Behandlungsmanagements notwendig: integrierte Konzepte für die präoperative Evaluation, für ein adäquates Atemwegsmanagement mit einer adaptierten Narkoseführung sowie für die Intensivtherapie und Schmerztherapie. Zudem erfordern diese Patienten speziell geschultes Krankenhaus- und Rettungspersonal, geeignetes Equipment sowie eine adäquate bauliche Ausstattung, für die zukünftig alle Krankenhäuser und Gesundheitseinrichtungen sorgen müssen. Dieses Praxishandbuch vermittelt umfassend die Theorie und Praxis der besonderen Voraussetzungen, Konzepte und Strukturen zur Behandlung und Versorgung von übergewichtigen oder adipösen Erwachsenen und Kindern.

Angiotensin converting enzyme inhibitors (ACEI) represent the first class of antihypertensive agents that was designed and developed on the basis of a well-defined physiopathological axis of arterial hypertension, a vascular dis­ order that is now becoming one of the major causes of morbidity/mortality, not only in developed societies but also in the highly populated developing coun­ tries [1]. CAPTOPRIL, the prototype of the'PRIL'family, which now comprises more than 40 molecule-species, was quite hazardous and the clinical develop­ ment almost failed when serious side-effects were reported in an alarmist fash­ ion in reputable scientific journals, such as the New England Journal of Medicine and Lancet. Squibb & Sons came very close to withdrawing CAPTOPRIL from clinical investigation [2]. However, after re-examination of the data obtained from different categories of patients and appropriate dose-adjustments, the clinical use of CAPTOPRIL turned out to be revolutionary. The prototype, as well as other members of the'PRIL'family became the starting point for numerous basic and clinical research programs, focusing on the interactions of ACEI with the kinin, endothelin, and nitric oxide systems, and the contribution of the receptors for AT I, AT 2, bradykinin Bland B, ETA and ET B to the pharmacological actions 2 of the respective peptides. This research activity led to the development of new pharmacological agents, such as the angiotensin receptor antagonists and, more recently, the neutral endopeptidase inhibitors. In the near future, bradykinin receptor antagonists also will be available to modulate ACEI phar­ macological actions.

Essential Medical Facts presents selected literature-based information clinicians need to know to provide informed patient care and avoid medical misadventures. Facts that can help make us better and safer clinicians include knowing the usefulness of palmar crease pallor in detecting anemia (not reliable), antibiotics that can cause a false positive opiate urine drug screen (fluoroquinolones), and an occasional early clue to testicular cancer (gynecomastia). Of course, keeping up to date on current medical knowledge and being curious about the implications of published research conclusions not only help assure superior clinical performance; they also bolster the preparation for board examinations. Robert B. Taylor, MD is the author and editor of more than two dozen medical books and several hundred published articles, as well a veteran of both rural private practice and chairmanship of a medical school clinical department. Essential Medical Facts is written for clinicians in all specialties, at all stages of professional life. It is a “must have” book for students, residents and practicing physicians, as well as nurse practitioners and physician assistants actively involved in clinical diagnosis and management of disease.

The European Society of Hypertension Guidelines are imparted throughout the text in order for the reader to achieve'better practice.'The data provided is all evidence-based and clearly referenced.Professor Guiseppe Mancia is a leading light on the management and treatment of hypertension and is particularly expert on the angiotensin II recept

A classic nephrology reference for over 20 years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch's The Kidney is your number one source for information.• Offers the most comprehensive coverage of fluid and electrolyte regulation and dysregulation in 51 completely revised chapters unlike Brenner & Rector's The Kidney which devotes only 7 chapters to this topic.• Includes 3 sections, 31 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Brenner & Rector's only devotes 5 chapters to these topics.• Previous three editions edited by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology. The title for the fourth edition has been changed to reflect their considerable work on previous editions and they have also written the forward for this edition. • Over 20 million adults over age 20 have chronic kidney disease with the number of people diagnosed doubling each decade making it America's ninth leading cause of death.

With color illustrations throughout, this book analyzes the implications that transplantation and immunosuppression can hold for patients. Discussing the many complications that may occur after kidney transplantation, this source is a must for anyone caring for patients recovering from this type of procedure.

Filling a large gap in the literature, this book focuses on the management of patients who have, or are at risk of developing, cardiovascular disease. Designed to serve as a resource for the busy, practicing clinician, the approach is evidence-based but practical. Conceptual development and the exploration of biochemical and physiological mechanism

Seit 1985 wird der deutsche Arzneimittelmarkt im Arzneiverordnungs-Report analysiert. Datengrundlage ist die Vollerfassung von 400 Millionen Rezepten für die Patienten der gesetzlichen Krankenversicherung. Die Arzneimittelausgaben nahmen 2004 erstmals seit 12 Jahren um 2,5 Mrd. € auf 21,7 Mrd. € durch das GKV-Modernisierungsgesetz ab. Wesentliche Elemente der Kostensenkung waren der Ausschluss rezeptfreier Arzneimittel aus der vertragsärztlichen Versorgung, erhöhte Rabatte der Arzneimittelhersteller an die Krankenkassen, erhöhte Patientenzuzahlungen und die Einführung einer Praxisgebühr. Aktuelle Verordnungstrends werden an 3000 Arzneimitteln in 46 Indikationsgruppen dargestellt. Besonders eingegangen wird auf: Bewertung von 33 Neueinführungen des Jahres 2004, Einsparerfolge bei Generika und umstrittenen Arzneimitteln, Verordnungsprofil rezeptfreier Arzneimittel. Als Schwerpunkthema werden die Arzneiverordnungen pharmazeutischer Hersteller und ihr Produktsortiment im Kindesalter dargestellt. Immer noch problematisch ist hier die Anwendung von Arzneimitteln außerhalb der Zulassung (Off label). Noch häufiger werden bei Kindern Arzneimittel mit umstrittener Wirkung verordnet. Presseecho zum Arzneiverordnungs-Report 2004:'Bei Medikamenten droht neue Kostenlawine'Süddeutsche Zeitung 16.10.2004'Medikamente werden 2005 teurer'Tagesspiegel 16.10.2004'Rezeptfrei oft billiger als verordnet'Stuttgarter Nachrichten 16.10.2004'Kosten sinken - vorübergehend'Deutsches Ärzteblatt 22.10.2004

Compiled by an international team of nephrologists, this reference covers a wide variety of clinical, regional, and research issues related to the epidemiology, diagnosis, and treatment of kidney disease in ethnic populations-exploring current prevention strategies, treatment outcomes, and education and training practices in Africa, South America,

Organized in a reader-friendly format, this reference collects a vast amount of information on the underlying mechanisms of hypertension and applies them to day-to-day clinical practices -- focusing on recent developments in patient management, as well as the molecular, biological, physiological, pathophysiological, and pharmacological facets of hy

Now in its sixth edition, The Kidney and Hypertension in Diabetes Mellitus retains its position as the comprehensive resource for information on diabetic kidney disease. The book covers all aspects of renal involvement in diabetes and incorporates information from important publications and new trials conducted during the last three years. The new

Hypertension is common in patients with kidney disease for a number of reasons, including retention, inappropriate action by the renin-angiotensin system, and overactivity of the sympathetic nervous system. Of all causes of hypertension, renal artery stenosis (narrowing) has attracted considerable attention, because it was once thought to be a rare

The proven concept of the first edition has been continued in the second edition Including many new entries and completely revised A trilingual dictionary with more than 4300 entries Offering an indispensable vocabulary of basic medical terminologyFor physicians, medical students and everybody connected with the medical professionContains important expressions and phrases, essential for professional success in foreign countriesEnabling communication with patients of different nationalities as well as medical report writing in foreign languagesAcknowledges the particularities within intricacies of Brazilian Portuguese

Taking stock of advances in clinical recognition, laboratory testing, and pharmacologic therapy as well as basic aspects of pathogenesis, the Third Edition of Heparin-Induced Thrombocytopenia reinforces its standing as the leading guide to accurate diagnosis and effective management of this complex condition. Featuring added chapters on bivalirudin

Developed through the collaboration of leading experts, Management of Diabetic Nephropathy provides background information on diabetes mellitus and nephropathy as well as a description of the genetic basis and factors causing progression of this disease. The book reviews the various therapeutic options at all stages of renal disease from mild to en

Not too long ago, it was thought that inflammation of blood vessels was the sole manifestation of systemic autoimmune diseases. Today, however, we know that disorders of coagulation, injuries to both neutrophils and endothelial cells, and certain lipids and amino acids are all intricately involved in the development of vascular disease. How are all