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Winner of a Christopher Award—now with a discussion guide “Perhaps one lesson to draw from the pandemic, with help from books like this one, is that the ICU experience can be changed for the better” (The Washington Post) for both patients and their families. You will learn how in this timely, urgent, and compassionate work by a world-renowned critical care doctor.In this rich blend of science, medical history, profoundly humane patient stories, and personal reflection, Dr. Wes Ely describes his mission to prevent ICU patients from being harmed by the technology that is keeping them alive. Readers will experience the world of critical care through the eyes of a physician who drastically changed his clinical practice to offer person-centered health care and through cutting-edge research convinced others to do the same. Dr. Ely's groundbreaking investigations advanced the understanding of post– intensive care struggles and introduced crucial changes that reshaped treatment: minimizing sedation, maximizing mobility, and providing supportive aftercare. Dr. Ely shows that there are ways to bring humanity into the ICU and that “technology plus touch” is a proven path toward returning ICU patients to the lives they had before their hospital stays. An essential resource for anyone who will be affected by illness—which is all of us.

The quintessential reference for bedside medical management of neurocritical care patientsMedical management of patients in the neurocritical care unit (NCCU) often spells the difference between life or death and return to normal function or a lifetime disability. As such, it is vital that patients with life-threatening neurological and neurosurgical illnesses receive prompt diagnosis and rapid interventions in the NCCU.The Jefferson Manual for Neurocritical Care by renowned neurosurgeon Jack I. Jallo, neurointensive care physician Jacqueline S. Urtecho, and distinguished colleagues is a high-yield pocket resource ideal for the bedside care of patients with serious, life-altering diseases. Nineteen concise chapters encompass cerebrovascular, neuromuscular, oncologic, and traumatic conditions, as well as core clinical topics applicable to the care of neurocritical patients.Key HighlightsEvidence-based management strategies created at Thomas Jefferson University's Vickie and Jack Farber Institute for Neuroscience presented in reader-friendly algorithms, pictures, and chartsGeneral chapters cover brain death, sodium dysregulation, nutrition, sedation, pain management, neuromonitoring, and ventilation strategiesDisease-specific chapters featuring succinct, bulleted format include epidemiology, causes, diagnostic tests, treatment options, symptoms, common clinical presentation, risk factors, differential diagnoses, and moreThis manual is an indispensable resource for neurocritical care residents and fellows, NCCU nurses, nurse practitioners, physician assistants, general intensive care physicians, and neurointensivists.

Das vorliegende Buch gibt einen umfassenden Überblick über den aktuellen Stand und die Entwicklungen im Bereich der Telemedizin in Deutschland. Das Herausgeberteam aus einem der führenden Telemedizinzentren Deutschlands und ein interdisziplinäres Autorenteam liefern wesentliche Grundlagen sowie zahlreiche Anwendungsbeispiele aus dem stationären und ambulanten Bereich. Zudem werden Chancen und Risiken der Telemedizin erörtert, so dass der Leser gut für die Zukunft in Klinik oder Praxis gerüstet ist. Ein Grundlagen- und Nachschlagewerk für alle Ärzte, die sich für digitale Zukunft im Gesundheitswesen wappnen und ihre Patienten optimal versorgen möchten.

The aim of this book is to educate and train practitioners in the safe and professional use of diagnostic ultrasound imaging in the visualization and interpretation of various cerebral conditions not only in neurointensive care, but also in the operating room and, in general, cardiothoracic and neurocritical care settings. It is chiefly intended for anaesthetists and intensivists with a basic knowledge of ultrasound physics, but also for neurosurgeons and neurologists.All chapters were coordinated by the Editors, with experiences in hands-on courses on Echography and Doppler of the Brain, and prepared by international experts. The book covers from basic principles to estimation of intracranial pressure and cerebral perfusion. The topics cover emergency department and prehospital brain US as part of POCUS and US multiorgan evaluation to general intensive care, neurointensive care and anesthesia, including special populations as pregnant and children and setting as LMIC. Clinical scenarios complete the book. An innovative and unique guide that equips readers to perform bedside and non-invasive assessments for a range of cerebrovascular diseases.

This unique work from acclaimed author Dr. Paul Marino (Marino's The ICU Book, The Little ICU Book) challenges the traditional notion that the human body thrives on oxygen, and that promoting tissue oxygenation is necessary for promoting life. This concept fails to recognize that oxygen is a destructive molecule that also damages the human body. Instead of welcoming oxygen, the human body limits exposure of the tissues to oxygen, and employs an army of chemical antioxidants to combat the damaging effects of oxygen. This “oxygen protective” human design represents a new paradigm for the relationship between oxygen and human survival, and it has important implications for the excessive and unregulated use of oxygen in clinical practice.

This book offers a comprehensive overview of the basic physiology of the cardiac and pulmonary systems, tools for cardiopulmonary monitoring, and related issues in the management of specific conditions. The volume is divided into three main parts. The first part examines the functional basis of normal and abnormal physiology, organized into cardiac and pulmonary units and followed by a “combined” interactive component. The next section discusses cardiopulmonary monitoring tools and variables and is also divided into cardiac (e.g, echocardiography, heart rate, cardiac output), pulmonary (e.g, lung volume, pleural pressure, electrical impedance tomography), and combined tools such as radiology/MRI and tissue perfusion tests. The third section concerns the management and application of specific clinical problems such as pulmonary hypertension, cardiac shunts, cardiogenic shock, and ECMO with an emphasis on the physiological basics. Cardiopulmonary Monitoring: Basic Physiology, Tools, and Bedside Management for the Critically Ill is an essential resource for physicians, residents, fellows, medical students, and researchers in cardiology, critical care, emergency medicine, anesthesiology, and radiology.

The Medical-Legal Aspects of Acute Care Medicine: A Resource for Clinicians, Administrators, and Risk Managers is a comprehensive resource intended to provide a state-of-the-art overview of complex ethical, regulatory, and legal issues of importance to clinical healthcare professionals in the area of acute care medicine; including, for example, physicians, advanced practice providers, nurses, pharmacists, social workers, and care managers. In addition, this book also covers key legal and regulatory issues relevant to non-clinicians, such as hospital and practice administrators; department heads, educators, and risk managers. This text reviews traditional and emerging areas of ethical and legal controversies in healthcare such as resuscitation; mass-casualty event response and triage; patient autonomy and shared decision-making; medical research and teaching; ethical and legal issues in the care of the mental health patient; and, medical record documentation and confidentiality. Furthermore, this volume includes chapters dedicated to critically important topics, such as team leadership, the team model of clinical care, drug and device regulation, professional negligence, clinical education, the law of corporations, tele-medicine and e-health, medical errors and the culture of safety, regulatory compliance, the regulation of clinical laboratories, the law of insurance, and a practical overview of claims management and billing. Authored by experts in the field, The Medical-Legal Aspects of Acute Care Medicine: A Resource for Clinicians, Administrators, and Risk Managers is a valuable resource for all clinical and non-clinical healthcare professionals.

Part of the Mount Sinai Expert Guide series, this outstanding book provides rapid-access, clinical information on all aspects of Critical Care with a focus on clinical diagnosis and effective patient management. With strong focus on the very best in multidisciplinary patient care, it is the ideal point of care consultation tool for the busy physician.

This concise, accessible book covers anesthesia for hepatico-pancreatic-biliary (HPB) surgery and transplantation, based on randomized clinical trials, meta-analyses, case series, reports, and hands-on experience. The anatomy, physiology, pathophysiology and clinical consequences are discussed, and the close ties between HPB resection and transplant anesthesia are explored. The content reflects current real-world practice, as liver and pancreatic transplant surgeries have substantially improved in terms of blood-loss reduction, fast tracking and reduced risk. The book also addresses anesthetic aspects in connection with the recently introduced and rapidly expanding practice of laparoscopic surgery; with enhanced recovery; and with pancreatic surgery. Anesthesia for Hepatico-Pancreatic-Biliary Surgery and Transplantation is intended for aspiring HPB and transplant anesthetists, anesthesia trainees, and consultants with experience in HPB anesthesia who want to see whether or not they're up to date on the current standards.

This book acts as a portable and easy-to-understand reference for surgical trainees or young faculty members that are interested in reviewing procedures on the way to the operating room. This second edition aims to provide a practical hands-on approach to operative trauma management. Following the success of the first edition, chapters were revised, updated, and added due to substantial changes in trauma care over the past few years. Several new experts contributed their knowledge and techniques inside this new edition. For example, chapters on fasciotomy and resuscitative endovascular balloon occlusion of the aorta (REBOA) have been added.The second edition of The Shock Trauma Manual of Operative Techniques is a valuable reference for practicing surgeons in the community and serves to aid trauma practitioners as they attempt to deal with operative challenges.

The eighth edition of this international bestselling emergency medicine handbook has been completely revised and updated to include the latest evidence-based guidelines and treatment protocols underpinning best practice in emergency medical care. Carefully designed to suit the needs of interns and resident doctors working in the emergency department as well as specialist trainees, the book covers the full range of emergencies - general medical, infectious disease and foreign travel-related, toxicological, surgical, paediatric, obstetric and gynaecological, ophthalmic and psychiatric - as well as practical procedures and administrative and legal issues.

Offering a comprehensive review of the neuropathology of SARS-CoV-2, Neurological Care and the COVID-19 Pandemic provides up-to-date coverage of the wide array of the pathogen's neurological symptoms and complications. Drs. Ahmad Riad Ramadan and Gamaledin Osman discuss the neuropathology of SARS-CoV-2, its neurological manifestations, and the impact the pandemic has had on the care of patients with pre-existing neurological conditions. The authors also offer an overview of emerging treatments and vaccines, as well as ways healthcare systems have reorganized in order to respond to the pandemic. Offers a thorough discussion of the impact the virus has had on the care of patients with neurological ailments, accompanied by recommendations on how to care for these patients. Covers the impact of COVID-19 on patients with cerebrovascular diseases, seizures, demyelinating diseases, neuromuscular disorders, movement disorders, headache disorders, cognitive disorders, and neuro-oncological disorders. Includes a detailed case study of how one healthcare system hit hard by COVID-19 successfully transformed itself to respond to the challenges imposed by the pandemic. Consolidates today's available information on this timely topic into a single, convenient resource.

Dieses praxisorientierte Buch behandelt ein stetig wachsendes Teilgebiet der Neurologie grundlegend. Es stellt sich den bekannten und den neuen Infektionserkrankungen des zentralen Nervensystems und unterstützt behandelnde Ärzte bei der Diagnosefindung und dem Management. Praxisnah mit übersichtlichen Tabellen, Abbildungen und Kernaussagen, kann dieser kompakte Leitfaden eine wertvolle Hilfe im ärztlichen Alltag sein.Das Werk schult den diagnostischen Blick, der neben der interdisziplinären Zusammenarbeit mit einem Tropeninstitut und neben Ausdauer und Besonnenheit in der Patientenbetreuung von entscheidender Bedeutung ist.

Fully updated for a second edition, the Oxford Handbook of Pre-hospital Care is the invaluable guide to providing high-quality care in a pre-hospital environment. Evidence-based and reflecting new developments in regulation and practice, this second edition is designed to provide key information for all immediate care practitioners, including doctors, paramedics, emergency medical technicians, and community responders. The text has been cross-referenced with the Joint Royal Colleges Ambulance Liaison Committee (JRCALC) handbook to ensure full clinical relevance. Reflecting the major advances in delivery of pre-hospital care, including the greater survival benefits for heart attacks and major trauma when delivering patients directly to higher levels of care, the evolution of the paramedic role into critical care paramedics, roadside rapid sequence induction of anaesthesia, and the introduction of mechanical chest compression devices, this new edition is the ideal companion for those involved in delivering pre-hospital care. It also links to relevant online databases and mobile apps that can assist with calculations, and contains key algorithms and formulae to ensure good care. The Oxford Handbook of Pre-hospital Care is the comprehensive quick-reference guide to all medical and trauma conditions regularly encountered in the immediate care setting.

The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities.Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.

This is the story of one man's hobby and its overwhelmingly positive effect physically, emotionally, socially, and mentally on his life. The hobby is scuba diving, but not on the reefs of southern seas. This is about diving in Halifax Harbour. Diving summer and winter in one of the biggest and deepest harbours in the world has given Bob a view of history that few will ever witness. Inquisitive and energetic, the author spins yarns about the strange and fascinating objects he finds and the hair-raising moments he has experienced, from coming to the surface and seeing the boat drifting out of sight to arriving on the surface in a snowstorm and having to navigate by compass to find the shore. The bottom of Halifax Harbour has collected artifacts over the centuries from around the world. Each find gets picked up, cleaned, researched, and documented. The author's database is a gold mine of little details about what arrived, eventually got dumped into the ocean, and is now sitting on display at home and in museums as a reminder of what once was. The author takes the reader under warships, container ships, and tugboats, through huge docks, and under the ice. Along the way, he reflects on the toll that our civilization is taking on the ocean, of seagulls trying to break open golf balls to find food, of crabs trapped inside tires, and fish that take refuge in castoff bottles and grow too big to stay in but also too big to get out.

Palliativversorgung von Kindern, Jugendlichen und jungen Erwachsenen fängt bei grundlegenden Aspekten der Organisation, der Konzepte, ethischen und rechtlichen Fragen an. Die 3. Auflage legt den Fokus auf diese Grundlagen und widmet sich ausführlich den Fragen jenseits von konkreter Schmerztherapie und Symptomkontrolle, die in einem zweiten Buch von Boris Zernikow und zahlreichen Experten in diesem Feld behandelt werden.

This book is an invaluable resource for the diagnosis and management of neurological illnesses in the emergency setting. It emphasizes the quality of prognosis to be contingent on the prompt management of these illnesses.Emergency Neurology, Second Edition follows the exemplary format of the previous edition, with comprehensive chapters on every neurological emergency, including stroke, headache, back pain, dizziness, vertigo, syncope, visual loss, diplopia, facial nerve palsy, weakness, altered mental status, coma, meningitis and encephalitis, seizures, and spinal cord disorders. Chapters emphasize the clinical presentation, diagnostic studies and management, and include high-quality images and tables that are invaluable for rapid diagnosis and therapy.Building off its predecessor's success, Emergency Neurology, Second Edition is an excellent reference for neurologists, emergency room physicians, internists, neurology residents, emergency medicine residents, and internal medicine residents.

This book, now in its 2nd edition, discusses, explains and provides detailed, up-to-date information on physics applied to clinical practice in anesthesiology and critical care medicine, with the aid of simple examples from daily life. Almost everything that happens around us, including in the operating room and intensive care units, can be explained by physical laws. An awareness and understanding of relatively simple laws such as the Hagen-Poiseuille equation, or of slightly more complex topics such as harmonic motion and electromagnetism, to name just a few, offer anesthesiologists and intensivists fascinating insights into why they do what they do.After an introductory chapter that brushes up on all the (few) mathematics the reader will need to face the book, with many practical examples and clinical applications, each of the following 20 chapters deals with some everyday phenomena, explains them with one or more physical laws, and shows why these laws are important in anesthesia and critical care practice. Many illustrations are included for extra clarity. This enriched and updated edition of Physics for Anesthesiologists is intended for anesthesiologists, intensivists, anesthesia and intensive care medicine teachers and trainees, as well as medical students.

This book provides a concise yet comprehensive overview on the use of opioids in the ICU, offering practical, real-world recommendations on opioid utilization and alternative therapies. The text explains the physiology and assessment of pain and the need for analgesia in the ICU, details the pharmacology of opioids and their use in providing analgesia, sedation, and comfort for patients during critical illness, and summarizes advanced pharmaceutical and surgical approaches to pain management and procedural applications that can supplement, minimize, or replace opioids for the ICU patient. The book also includes algorithms and step-by-step approaches on navigating the delicate balance between the relief of suffering and the adverse effects of opioids, as well as a dedicated section on the management of critically ill patients with preexisting opioid tolerance. Written by experts in the field, Opioid Use in Critical Care: A Practical Guide is a valuable resource for ICU providers who treat and manage critically ill patients with opioids.

This book presents the state of the art in high-flow nasal cannula (HFNC), an oxygen therapy technique that has recently proven to be a very promising approach to supporting respiratory function in several medical fields.In the opening part of the book, readers will learn the differences between high-flow and low-flow techniques and gain an overview of HFNC's technical aspects and physiological effects. The book subsequently describes the pathophysiological mechanisms involved in different respiratory diseases, analyzing how this technique positively impacts patients'respiratory status. The authors highlight clinical applications of HFNC, both in adults and in children, in various clinical settings – e.g. intensive care and semi-intensive care unit, emergencies, rehabilitation etc. – and present tips, tricks and pitfalls, as well as up-to-date reports on technical issues. The book is intended for pneumologists, intensivists, anesthesiologists, ED doctors, rehabilitation therapists, internists and oncologists, as well as fellows and nurses in these fields.

This book provides a comprehensive overview of critical care obstetrics. The text reviews different diseases and complications that can cause a pregnant patient to go into critical condition, while outlining treatment and management strategies for effective patient care. Critical scenarios covered include obstetric hemorrhage, pulmonary edema in preeclampsia, cardiac arrest, septic shock, abdominal hypertension, uterine rupture, and acute renal failure. Written by experts in the field, Obstetric Catastrophes: A Clinical Guide is a valuable resource for critical care intensivists, obstetricians, and any practitioners involved in the treatment and management of the obstetric patient in critical condition.

This book provides a comprehensive overview of improving critical care survivorship. Comprised of four sections, the text presents interventions that can be used to improve patient outcomes and reduce the burden of post-intensive care syndrome across the arc of care, from the ICU to returning home. The first section of the text focuses on preventing adverse outcomes in the ICU, with an emphasis on implementing early mobilization, engaging and supporting families, and employing various forms of therapy. The second section revolves around enhancing recovery post-ICU, focusing on physical and neurocognitive rehabilitation programs, peer support, and poly-pharmacy management. Community reintegration is the subject of the third section, with emphasis on socioeconomic reintegration, healthcare utilization, and volunteerism in ICU recovery. The book concludes with a section on future considerations, specifically spotlighting preliminary ideas that address long-term sequelae and international collaboration to solve critical care challenges. Written by experts in the field, Improving Critical Care Survivorship: A Guide for Prevention, Recovery, and Reintegration is a valuable resource for critical care clinicians and researchers interested in improving the quality of patient survival after ICU admission.

This extensively updated textbook is a comprehensive study guide that covers pediatric critical care principles and specific disease entities commonly encountered by the pediatric critical care medicine (PCCM) practitioner. Pathophysiologic aspects unique to the pediatric patient are emphasized. The first edition has become a highly utilized text for pediatric critical care fellows. The second edition will prove even more valuable to the fellow in-training and indeed to any clinical pediatric intensivist. In addition to updating the chapters from the previous edition, there are new chapters on topics such as central nervous structure and function, palliative care, child abuse and practical biostatistics. Pediatric Critical Care: Text and Study Guide is an invaluable clinically focused resource for PCCM practitioners. Allowing for concise reading on specific topics, this book acts as both text and study guide covering advanced physiology, pathophysiology, diagnostic considerations and treatment approaches that should be mastered by the higher level PCCM practitioner.The large number of illustrations complements the text in each chapter that also includes key references and case-orientated questions that help reinforce important ideas learned in the chapter.

This unique book discusses the management of neurocritical care patients, including basic concepts, pathophysiologic principles, monitoring, treatment indications, and factors that affect outcomes in patients requiring neurocritical care assistance. It addresses the need to improve continuing education in this area, highlighting patient care in the perioperative period. This is the first book to provide a simplified overview for neurosurgeons and neurologists to understand the neurocritical patient journey. It is divided into three parts: the first covers the basics concepts, from monitoring to the interpretation of exams; the second explores general management of specific situations encountered in intensive care and the last part includes prognostic and rehabilitation models, as well as new perspectives. Thanks to the accessible, neurosurgical specific language, the book is well suited for all professionals involvedin neurocritical care, including students, but is also a valuable resource for residents and researches, as well as experienced neurosurgeons or neurologists looking for updated information and guidelines.

A world-renowned critical-care doctor offers hope for patients, their families, and the future of medicine in this timely, urgent, and compassionate work about the devastating and little-known physical and emotional effects of ICU stays. As COVID-19 survivors are discharged from hospitals, grateful to be alive, most don't realise that the hardest part of their battle may be about to begin. Many will return home and struggle with long-term physical, mental, and emotional problems either caused or exacerbated by the life-saving treatment they received in intensive care. They'll join the ranks of critical-care survivors whose lives are completely upturned by a hospital stay. More than half of the patients admitted to ICUs will struggle with post-intensive care syndrome, which can include Alzheimer's-like cognitive deficits, PTSD, muscle and nerve damage, and depression. Their personal and professional lives can suffer irreparably. Worst of all, no one seems to understand that they have an illness at all. Not even their doctors. Dr Ely is now a leader in the field of ICU survivorship — advocating for compassionate care in the technology-driven enclave of the modern ICU — especially relevant during the coronavirus pandemic. In Every Deep-Drawn Breath, Dr Ely sounds a warning for the millions of people who will be admitted to ICUs in coming years and a wake-up call for healthcare professionals — himself included — to turn their gaze from the latest life-saving machines to really see, as he says, ‘the person in the patient'.

This book provides a practically applicable guide to injuries, diseases, and disorders affecting the head, neck, and dental region seen within accident and emergency departments. These regions contain a number of specialized structures each with individual neural, muscular and vascular elements, meaning that the study of these anatomical areas is complicated and often quite daunting. Chapters in this work aim to break the treatment of such injuries and diseases into an easy-to-digest format via chapters featuring a symptom-based approach. Therefore, enabling the reader to quickly access the information they require when treating patients with a variety of disorders in the emergency room. Diseases and Injuries to the Head, Face and Neck: A Guide to Diagnosis and Management is a concise overview of how to deal with head, neck, and dental emergencies and is an important up-to-date resource for all medical professionals and trainees who encounter these patients.

This is a practical guide to the use of simulation in emergency medicine training and evaluation. It covers scenario building, debriefing, and feedback, and it discusses the use of simulation for different purposes, including education, crisis resource management and interdisciplinary team training. Divided into five sections, the book begins with the historical foundations of emergency medicine, as well as education and learning theory. In order to effectively relay different simulation modalities and technologies, subsequent chapters feature an extensive number of practical scenarios to allow readers to build a curriculum. These simulations include pediatric emergency medicine, trauma, disaster medicine, and ultrasound. Chapters are also organized to meet the needs of readers who are in different stages of their education, ranging from undergraduate students to medical directors. The book then concludes with a discussion on the future and projected developments of simulation training. Comprehensive Healthcare Simulation: Emergency Medicine is an invaluable resource for a variety of learners, from medical students, residents, and practicing emergency physicians to emergency medical technicians, and health-related professionals.

Carotenoids are a large class of isoprenoid pigments produced by plants and certain microbes. More than 700 naturally occurring carotenoids have been identified. Apocarotenoids are tailored from carotenoids by oxidative enzymes. Apocarotenoids act as visual or volatile signals to attract pollinating and seed dispersal agents. They are also the key players in allelopathic interactions and plant defense. Biology, Chemistry and Applications of Apocarotenoids provides detailed account of the fundamental chemistry of apocarotenoids and the basic methods used in carotenoid research, and critical discussions of the biochemistry, functions, and applications of these important compounds. Topics covered in the proposed book include various aspects of the roles of apocarotenoids in colour and colouration, photosynthesis and other photofunctions and protection. The formation and roles of carotenoid metabolites and breakdown products as perfume/aroma compounds are also be outlined. Features: Provides an organized overview of apocarotenoids and their chemistry and biological functions Focuses on recent discoveries on apocarotenoids, their nature and functions. Details potential uses of apocarotenoids in agriculture, pharmacy, food industry, and apocarotenoid production at industrial level This book has been written by leading experts in apocarotenoid research and gives a comprehensive overview on the diversity of apocarotenoid compounds and would serve as a reference book for researches in Plant Physiology, Molecular Biology, Biochemistry, Biophysics and Medicine.

This book offers an overview of acute care surgery around the world, focusing on the four main branches of this novel subdiscipline: trauma, general emergencies, critical care, and rescue surgery. The book's primary goal is to provide a general view of acute care surgery, while addressing the most important issues in depth.The content is divided into three parts, the first of which is dedicated to the general organization of trauma centers, including the composition of modern trauma teams. Protocols of activation and action for the trauma team, as well as damage control procedures both in the emergency room and in the surgical theatre, are described. The book also addresses the development of a trauma registry, together with the quality assessment process that can be applied.In turn, the second part describes the principal protocols for making diagnoses, with special attention to circumstances such as unstable hemodynamics, neurological deterioration, normal vital signs, and penetrating injuries. The book subsequently deals with the most important aspects of trauma to the abdomen, chest, and pelvis, with notes on both surgical and intensive care issues. Practical descriptions of how to treat principal injuries to various organs are also provided. Finally, the third part of the book is dedicated to the most frequent general surgical emergencies and rescue surgical approaches, and includes information on diagnostic support with point of care ultrasound and endoscopic advanced techniques. Presenting cutting-edge strategies, this book will be of interest to professionals involved in surgical and intensive care for emergency conditions, such as colonic perforations, obstructions, acute pancreatitis, biliary tree stones, and caustic injuries.

The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

Although most clinicians are aware of the problem of antimicrobial resistance, most also underestimate its significance in their own hospital. The incorrect and inappropriate use of antibiotics and other antimicrobials, as well as poor prevention and poor control of infections, are contributing to the development of such resistance. Appropriate use of antibiotics and compliance with infection prevention and control measures should be integral aspects of good clinical practice and standards of care. However, these activities are often inadequate among clinicians, and there is a considerable gap between the best evidence and actual clinical practice. In hospitals, cultural determinants influence clinical practice, and improving behaviour in terms of infection prevention and antibiotics-prescribing practice remains a challenge. Despite evidence supporting the effectiveness of best practices, many clinicians fail to implement them, and evidence-based processes and practices that are known to optimize both the prevention and the treatment of infections tend to be underused. Addressing precisely this problem, this volume offers an essential toolkit for all surgeons and intensivists interested in improving their clinical practices.

This book covers the up-to-date advancement of respiratory monitoring in ventilation support as well as detecting the physiological responses to therapeutic interventions to avoid complications. Mechanical ventilation nowadays remains the cornerstone in life saving in critically ill patients with and without respiratory failure. However, conclusive evidences show that mechanical ventilation can also cause lung damage, specifically, in terms of ventilator-induced lung injury.Respiratory monitoring encloses a series of physiological and pathophysiological measurements, from basic gas exchange and ventilator wave forms to more sophisticated diaphragm function and lung volume assessments. The progress of respiratory monitoring has always been accompanied by advances in technology. However, how to properly conduct the procedures and correctly interpret the data requires clear definition.The book introduces respiratory monitoring techniques and data analysis, including gas exchange, respiratory mechanics, thoracic imaging, lung volume measurement, and extra-vascular lung water measurement in the initial part. How to interpret the acquired and derived parameters and to illustrate their clinical applications is presented thoroughly. In the following part, the applications of respiratory monitoring in specific diseases and conditions is introduced, including acute respiratory distress syndrome, obstructive pulmonary diseases, patient-ventilator asynchrony, non-invasive ventilation, brain injury with increased intracranial pressure, ventilator-induced diaphragm dysfunction, and weaning from mechanical ventilation.This book is intended primarily for ICU physicians and other practitioners including respiratory therapists, ICU nurses and trainees who come into contact with patients under mechanical ventilation. This book also provides guidance for clinical researchers who take part in respiratory and mechanical ventilation researches.

This book focuses on the technical, cognitive, and behavioral skills needed to implement an extracorporeal membrane oxygenation (ECMO) simulation program. It describes these programs on the individual, team, and hospital system level, and includes the history of ECMO simulation, its evolution to its current state, and future directions of technology and science related to ECMO simulation. Divided into six sections, chapters describe both the theoretical as well as the practical aspects of ECMO simulation, including a pictorial guide to setting up an ECMO simulation circuit and how to recreate ECMO emergencies. It is a pragmatic guide that emphasizes the necessary practical items and discussions necessary to plan, set-up, orchestrate, and debrief ECMO simulations for different types of learners in different Comprehensive Healthcare Simulation: ECMO Simulation - A Theoretical and Practical Guide is part of the Comprehensive Healthcare Simulation Series, and this book is intended for educators, simulation technologists, and providers involved in ECMO programs who recognize the value of simulation to improve ECMO outcomes.

Fundamentals of Frontline Surgery is an easy to read text, written by world class faculty, that provides clinicians with succinct and didactic information about what to do in high intensity, resource limited situations.With global conflicts and humanitarian emergencies on the rise, there has been a dramatic uptake in the number of volunteers for both military and humanitarian operations. This manual aids best practice and fast decision making in the field.

This evidence-based guide is the first of its kind to outline the surgical and perioperative management of patients with anatomical anomalies and support clinical decision-making under these difficult circumstances. Presented in a simple, accessible format and organized by anatomical area, this book contains all the essential topics required by trainees and practitioners to assess the patient quickly, diagnose anatomic anomalies, determine the feasibility and safety of the planned surgical and anesthetic procedures, and arrange for advanced consults and care, if needed. Newer techniques for surgical and anesthetic management of patients with anatomic anomalies are presented to facilitate practitioners'development of their skills. Chapters include the latest ultrasound techniques and images, as well as case studies.Physicians, nurses, and trainees involved in the surgical, anesthetic, perioperative,or critical care of patients will find this guide to be their go-to resource in the OR, lab, or pain clinic.

Atlas of Pediatric and Neonatal ICU EEG is the first and only atlas to provide a comprehensive overview of the EEG patterns encountered in critically ill neonates and children, with emphasis on their significance and implications for patient care. EEG monitoring is an essential component of neurocritical care, and the patterns seen in critically ill children and neonates are often distinctly different from those found in critically ill adults or encountered in an epilepsy monitoring unit or outpatient neurophysiology laboratory. This resource provides expert guidance in the interpretation of neonatal and pediatric critical care EEG with hundreds of examples and detailed descriptions to enhance understanding and facilitate better outcomes for EEG monitoring in children. The chapters begin by addressing the basics of each topic before focusing on specific EEG patterns and their relevance to a particular disease state. Dedicated chapters on rhythmic and periodic patterns, status epilepticus, quantitative EEG analysis, and multimodality monitoring provide a thorough grounding in ICU EEG skills and applications. The book concludes with a series of thirteen cases illustrating common scenarios to help clinicians apply lessons learned. 140 board-style questions targeting information covered on the epilepsy and clinical neurophysiology boards is included online along with 12 videos that further amplify chapter content. Incorporating the most recent American Clinical Neurophysiology Society guidelines for critical care EEG monitoring in neonates and children, this evidence-based atlas will be a trusted reference for critical care clinicians, neurologists, epileptologists, and other providers who care for critically ill neonates and children. Key Features: Detailed descriptions of the indications for and utility of ICU EEG monitoring in neonatal and pediatric patients Over 270 images of neonatal and pediatric ICU EEGs with explanations of key features Illustrative cases, board-style review questions with rationales, and videos facilitate understanding and application of the material covered in the images and text Takeaway points included at the end of chapters underscore essential information

This key textbook equips all nurses with the knowledge and skills required to care for the deteriorating patient in the clinical environment. The book emphasises the importance of systematic assessment, interpretation of clinical signs of deterioration, and the need to escalate the patient in a timely manner. Using a unique system-based approach, each chapter contains structured learning outcomes and concludes with a competence-based skills assessment to perfect the reader's practice skills. These skills are recommended as essential for every nurse in an acute area and key to successful practice. Restructured for ease of use, this new edition has been fully updated to match current guidelines, with new chapters on pain management and the ethics and ceilings of treatment. Written by senior nurses, this key textbook uses real life case studies to link knowledge to practice and is essential reading for all nurses working in acute care settings and undertaking study in the field.

Was ist unmittelbar notfallmäßig zu beachten bei der größten Gruppe von Patienten, die sich täglich selbst oder durch den Rettungsdienst in der Notaufnahme oder in ambulanten Strukturen vorstellen? Dieses Buch fokussiert auf die Primärpräsentation und entwickelt daraus das diagnostische Vorgehen und die weiteren therapeutischen Maßnahmen. Dabei werden Kriterien für die Entscheidung zur Überwachung, ambulanter oder stationärer Weiterbehandlung, diagnostischer Sequenzen und zeitlicher Dringlichkeit einzelner Schritte des Versorgungsprozesses besonders berücksichtigt. Jedes Kapitel wird durch eine Fallvignette eingeleitet, die das jeweils adressierte Krankheitsbild in typischer Ausprägung repräsentiert und auch besondere Herausforderungen in Diagnostik und Therapie aufzeigt. Je nach Thema ergänzt ein diagnostisches Flowchart, eine pathophysiologische Konzeption oder einen notfallmäßigen Ablauf visuell. Take-Home-Botschaften und als Besonderheit eine Box unter dem Stichwort „What to learn next'z.B. in Form von konkreten Trainings- und Weiterbildungsempfehlungen oder den Hinweis auf Simulationskurse oder bestimmte verfügbare Fortbildungsformate, schließen das Kapitel ab. Krankheitsbezogene Kapitel werden von Methodik (z.B. nicht-invasive Beatmung), Epidemiologie und Versorgungsforschung ergänzt. Im Bereich kardiovaskulärer Notfallmedizin gibt es z.T. relevante Unterschiede insbesondere in der klinischen Präsentation zwischen Frauen und Männern. Evidenz basierte Unterschiede werden in jedem Kapitel in einer besonderen Infobox „Frauen'hervorgehoben.

Undercover Epicenter Nurse blows the lid off the COVID-19 pandemic. What would you do if you discovered that the media and the government were lying to us all? And that hundreds, maybe thousands of people were dying because of it? Army combat veteran and registered nurse Erin Olszewski's most deeply held values were put to the test when she arrived as a travel nurse at Elmhurst Hospital in the epicenter of the COVID-19 pandemic. After serving in Iraq, she was back on the front lines—and this time, she found, the situation was even worse. Rooms were filthy, nurses were lax with sanitation measures, and hospital-acquired cases of COVID-19 were spreading like wildfire. Worse, people who had tested negative multiple times for COVID-19 were being labeled as COVID-confirmed and put on COVID-only floors. Put on ventilators and drugged up with sedatives, these patients quickly deteriorated—even though they did not have coronavirus when they checked in. Doctors-in-training were refusing to perform CPR—and banning nurses from doing it—on dying patients whose families had not consented to “Do Not Resuscitate” orders. Erin wasn't about to stand by and let her patients keep dying on her watch, but she knew that if she told the truth, people wouldn't believe her. It was just too shocking. Willing to go to battle for her patients, Erin made the decision to go deep undercover, recording conversations with other nurses, videos of malpractice, and more. She began to share what she found on social media. Unsurprisingly, she was fired for it. Now, Erin is standing up to tell the whole horrifying story of what happened inside Elmhurst Hospital to demand justice for those who fell victim to the hospital's greed. Not only must the staff be held accountable for their unethical actions; but also, this kind of corruption must be destroyed so that future Americans are not put at risks. The deaths have to end, and Erin won't rest until the bad actors are exposed. Undercover Epicenter Nurse: How Fraud, Negligence, and Greed Led to Unnecessary Deaths at Elmhurst Hospital is a shocking and infuriating inside exposé of the American healthcare system gone wrong. At the same time, it's the story of a woman who traveled from the small-town streets of Wisconsin, to the battlefields of Iraq, to the mean streets of Queens, on a quest to help fight for her country. With this book, the real battle has begun.

This comprehensively updated second edition features major revisions, 24 new chapters and more than 40 new authors, reflecting both the advances and key challenges within the field. Offering a systematic guide to the management of children and adults with severe traumatic brain injury throughout the entire chain of care, it includes evidence-based recommendations for each diagnostic and therapeutic measure, together with tips, tricks and pitfalls. The authors are all highly experienced clinicians and researchers who work with neurotrauma patients on a daily basis, and the editors represent the Scandinavian Neurotrauma Committee.The book helps professionals provide more systematic and higher-quality care in prehospital settings, primary hospitals, neurosurgical departments, neurointensive care units, and rehabilitation facilities. It is intended for all healthcare personnel involved in the multidisciplinary management of patients with head injuries, especially those in emergency care, neurosurgery, anesthesiology, radiology, and rehabilitation.

This book covers all aspects of modern techniques used in the rapidly developing field of adult critical care echocardiography, 3D transthoracic and transesophageal echocardiography, myocardial tissue velocity and deformation assessment, and contrast echocardiography. Featuring multiple color illustrations and echocardiographic images, it provides essential information on the technical aspects and current specifics of the equipment, anatomical imaging guidance, and physiological and pathological approaches with a focus on critically ill population. This book helps practitioners to not only understand the techniques and the applicability of these new technologies in various disease states, but also to apply them in a clinical setting. 3D echo, tissue deformation and contrast are opening tremendous new horizons for intensive care practitioners, offering them previously unimaginable insights into cardiac mechanics and anatomy and using non-invasive approaches for central hemodynamic diagnostic and monitoring management of intensive care patients. It also opens the way for completely new areas in clinical research. This book is useful for intensive care physicians, cardiologists, anesthesiologists, emergency physicians and sonographers involved in the provision of advanced echocardiographic services in intensive care units and in critical care environments. It is also suitable for students undertaking a Diploma of Diagnostic Ultrasound (Critical Care) with the Australasian Society of Ultrasound Medicine, adding to the existing literature used to prepare for the second and third parts examinations.

Atlas of Intensive Care Quantitative EEG is the first resource fully dedicated to quantitative EEG (QEEG) analysis, tailored to any physician or EEG technologist who works with critically ill patients. With the rise of continuous EEG monitoring in intensive care, clinicians are increasingly called on to make real-time clinical judgments with little formal guidance on how to interpret QEEG. This book is configured to meet daily practice challenges. It addresses not only technical fundamentals but also provides numerous examples of signature QEEG patterns and artifacts to instruct both untrained and experienced eyes.Comprehensive in scope, this unique atlas walks the reader from essential principles all the way through to practical pattern recognition. With full-page reference samples pairing raw EEG with quantitative EEG spectrograms, brief clinical vignettes, and explanatory captions noting significant features, this book provides a roadmap for understanding and applying QEEG data in critically ill patients. Unrivaled in the breadth of its coverage and level of detail, its thorough discussions of both normal and abnormal findings and QEEG artifacts set the standard for effective use of quantitative electroencephalography and trend analysis in the ICU. Complete with a broad range of patterns and page after page of full-color samples, this book is designed to be the authoritative QEEG reference for neurologists, intensivists, technologists, and trainees working in critical care settings.Key Features:Includes full spectrum of abnormal ICU QEEG findings with multiple examples of each pattern to assist readers in recognizing the range of findings encountered in clinical practiceContains more than 400 full-page vivid color QEEG examples paired with raw EEG to build interpretive skills and enhance clinical decision-makingConcise presentation of fundamental principles of QEEGDetailed analysis of QEEG artifacts that can be mistaken for abnormal findings

The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive reference book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

The care that a patient receives in the first hours after surgery is crucial to minimizing the risk of complications. The recovery room staff must manage both comatose and physiologically unstable patients, and deal with the immediate post-operative care of surgical patients. The Complete Recovery Room Book, Sixth edition, provides nurses, surgeons, and anaesthetists with up-to-date guidance and practical tips on the post-operative management of patients. Over 30 chapters, this resource covers key aspects of recovery room management from setting-up, monitoring and equipment, and managing symptoms as well as clear and concise explanations of physiology and pharmacology. Specific chapters address the unique post-operative needs of individual types of surgery and patient groups. Practical tips and short aphorisms are offered throughout the text to help retain practical information.

Cardiothoracic Critical Care covers an engaging collection of critical scenarios based on actual cardiothoracic intensive care unit events, ranging in topics from fundamentals of critical care to management of mechanical circulatory support devices. Each chapter discusses a unique case scenario, the appropriate diagnosis, and summarizes the most up-to-date evidence-based management recommendations and best practice guidelines. Combining years of critical care experience into a problem-based learning compendium, Cardiothoracic Critical Care is an ideal resource for the diverse group of medical providers and levels of experience working in the intensive care unit.

This book addresses the ethical problems that physicians have to face every day while caring for critically ill patients. Advances in medical technology, ageing societies worldwide, and their increased demands on health care systems have, on the one hand, led to better care and remarkable longevity in many parts of the world. On the other hand, however, improved treatments in many medical fields, amongst others in emergency and critical care, have resulted in more patients surviving with reduced quality of life. This entails tradeoffs for many patients, their families, and the teams caring for them. At the same time, health care expenditures have risen dramatically and have to be balanced against costs for other public goods. Finally, the humane aspects of care have often failed to keep pace with the remarkable technological strides made in recent years.In this book, experts in their respective fields describe compelling ethical challenges resulting from these discrepancies and discuss potential solutions. The book is primarily intended for clinicians who care for two of the most vulnerable patient subpopulations – those being treated in ambulances or emergency rooms, and those being treated at intensive care units – due in part to the fact that they may be temporarily or permanently incapacitated. Core medical skills, such as diagnosis and predicting outcomes, as well as implementing treatment, remain challenging. However, without adequate communication and collaboration both within the inter-professional treatment teams and between the teams and the patients/their families, delivering excellent care is difficult at best. Therefore, the so-called “soft skills” are given the attention they deserve in order to overcome the gap between technological progress and interpersonal standstill.

Cardiac implantable device (CIED) infections are a key issue since they have serious consequences in terms of morbidity, mortality and associated costs for healthcare systems. Such infections are highly complex, which has implications for prevention (several factors underlie its development), diagnosis (requiring patient specific integration of several elements), acute treatment (choice of the antibiotic, lead extraction procedure), as well as long-term management (CIED re-implantation strategy and follow-up). Dealing with CIED infections requires appropriate organization of healthcare provision, with the creation of integrated hub-spoke referrals, and it has prompted many of the recent developments in CIED technologies: leadless pacemakers, subcutaneous defibrillators, antibacterial envelops and lead extraction devices. This book systematically examines all aspects of this multifaceted condition, discussing each clinical and organizational issue in a separate self-contained chapter. It starts by reviewing the epidemiology/pathophysiology of CIED infections, and then addresses acute and long-term management. Offering a comprehensive overview of the prevention of infections, considering both current and future perspectives, the book also provides practical suggestions along with recommendations from the literature in the field. This is the first book entirely focused on CIED infections. Written by an international team of leading experts it will appeal to broad audience, including cardiologists, electrophysiologists, infectious disease specialists, internists, healthcare professionals, health service managers and providers, researchers and those working in industries involved in the field.

This book focuses on evidence-based occupational therapy in the care of older adults in different clinical settings, from home to acute hospital, from intensive care unit to rehabilitation centers and nursing homes. Occupational therapy has progressively developed as a new discipline aiming to improve the daily life of individuals of different ages, from children to older adults. The book first reviews the interaction between occupational therapy and geriatrics and then discusses in depth how occupational therapy interventions are applied in the community, in the acute hospital and in the nursing home. It highlights the key role of occupational therapy in the management of frail patients, including critically ill older patients and persons with dementia, and describes in detail how to maintain occupational therapy interventions across different settings to avoid the fragmentation of care. The ageing population requires new innovative approaches to improve the quality of life, and as such this book provides clinicians with handy, key information on how to implement occupational therapy in the daily clinical care of older adults based on the current scientific evidence.

This text provides a comprehensive, state-of-the-art overview of acute brain dysfunction in the critically ill. The book covers the basic pathophysiology of delirium, epidemiology, risk factors, outcomes associated with delirium, prevention and treatment of delirium, and challenges and techniques for improving delirium awareness. Written by experts in the field, Delirium: Acute Brain Dysfunction in the Critically Ill is a valuable resource for clinicians and practitioners that will help guide patient management and stimulate investigative efforts in this field.