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Single Photon Emission Computed Tomography (SPECT) cameras have revolutionarily changed nuclear imaging techniques and given us new diagnostic possibilities. They provide images that reveal subtle information about physiological and pathological processes. For some indications like cardiac and brain imaging, as well as tumor imaging, the importance of SPECT compared to planar imaging is beyond words. This book covers a broad spectrum of clinical applications of SPECT in the diagnosis of benign and malignant diseases. The opening chapters discuss the technology and physics of SPECT and its use in dosimetry. Applications covered include, among others, imaging of the bone and lungs, imaging of neuroendocrine tumors, cardiac imaging and brain SPECT for different indications like brain tumors and epilepsy. In each chapter, different radiopharmaceuticals for SPECT imaging were discussed and the scan procedures described. Readers will find this book to be a useful source for often performed SPECT imaging in the clinical routine.

Metabolic Bone Disease, Volume II describes the clinical disorders of bone and mineral metabolism characterized by elevated levels of circulating parathyroid hormone. This book emphasizes the relationship between hormonal synthesis, biological activity, and abnormalities in specific clinical syndromes. The metabolism and structure-function relationships of parathyroid hormone and other revealing interactions with specific receptors in target organs are also elaborated in this publication, including a basis for some understanding of the parathyroid hormone and vitamin D-'resistant states. Other topics discussed include the fundamental considerations of the physiology and biochemistry of parathyroid hormone; pathogenesis of renal osteodystrophy; and metabolic aspects of Paget's disease. This publication also covers the effects of hypercalcemia and normocalcemic disorders of mineral metabolism. This volume is beneficial to clinicians and students concerned with metabolic bone diseases.

Metabolic Bone Disease, Volume I covers the approach to a variety of disorders of mineral metabolism. The book discusses bone metabolism and calcium regulation; kidney function in calcium and phosphate metabolism; as well as the role of alkaline phosphatase in metabolic bone disorders. The text also describes the diagnostic value of bone biopsies; the etiology, clinical aspects, therapy, and the main syndromes of vitamin D deficiency, rickets, and osteomalacia; and the pathogenesis and therapy of osteoporosis. The pathogenesis and treatment of nephrolothiasis are also encompassed. Orthopedic doctors, physicians, endocrinologists, and people involved in the research of metabolic bone diseases will find the book invaluable.