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Healthcare systems globally are grappling with how best to implement effective and efficient patient-centred care while simultaneously trying to contain runaway costs and provide high quality. This book explores the essential enabling role of digital health, taking a socio-technical perspective and looking at the key facets of technology, people and process in turn.This book examines the opportunities of key digital health components, demystifying digital health and demonstrating how to use its key precepts effectively. The book presents evidence and anecdotes from stakeholders around the world, demonstrating the global relevance and the ability of digital health to uplift and upskill care delivery as it is applied commercially. Bridging academic theory and practice, this is a functional and accessible text for all digital health stakeholders.The text introduces critical issues and is suitable reading for students, practitioners and researchers in digital health and all healthcare-related domains.

For the past decade or so, research regarding women's health has become a major source of concern among health professionals. Due to the vast amounts of research, it has been difficult to amass a comprehensive source describing the challenges of physicians in this area of medical treatment and care. The Handbook of Research on Oncological and Endoscopical Dilemmas in Modern Gynecological Clinical Practice is a pivotal reference source that provides vital research on the application of clinical practices in regards to the health of women and prevention of severe, life-threatening diseases. While highlighting topics such as mental health, women's health, and preventative care, this publication provides an insight into critical dilemmas and issues in modern gynecologic oncology and endoscopy as well as the methods of daily clinical practice. This book is ideally designed for obstetricians, gynecologists, specialized physicians, medical professionals, academicians, researchers, and medical students.

With tremendous success of genomic research in discovering genetic variations determining human diseases, it is now time to re-evaluate how the environment affects disease risk by taking into consideration these genetic findings. This book addresses a rapidly growing interest in assessing the relations between environmental risk factors (such as diet, lifestyle) and human diseases, by considering the potential roles of genomic make-up. The book brings together a selection of chapters written by specialists with a variety of backgrounds such as epidemiology, nutrition, genetics, epigenetics, microbiome, biostatistics and bioinformatics. These authors are united in their concerns on the same scientific question – how do genomic events modify the effects of traditional, environmental risk factors on disease risk? This book offers an expert overview of the advances in the field of gene-environment interactions on human diseases and the cutting-edge methods used to detect the interactions. The majority of the chapters provide detailed up-to-date descriptions of the major findings of gene-environment interactions on various chronic diseases and risk factors such as obesity, lipids, diabetes, cardiovascular disease, cancer, multiple sclerosis, pancreatitis, Parkinson's disease, and longevity. The book also covers the potential influence of epigenetic events and microbiome on the relation between environment and diseases. In addition, the book also captures the potential application of the findings from this field in personalized prevention and treatment of human diseases.

The third edition of Psychiatric Care of the Medical Patient brings a classic reference text into the twenty-first century. It combines critical scholarship with the voice of expert clinicians who work at the interface of psychiatry with medical specialties. It is meant to be read for pleasure as well as consulted as a reference. The editors have worked with the authors to bring a consistent perspective to the book - one that sees the medical psychiatrist as an agent for bringing a more comprehensive perspective to medical care. Even seasoned and knowledgeable practitioners will find much that is new to them in this book. The volume covers topics in depth that other books in the field may not cover at all, such as the use of herbal and nutritional therapies for medical-psychiatric symptoms and syndromes, and the choice of questionnaires to supplement history-taking. It looks at old topics in a new way: The chapter on the physical examination applies psychometric considerations to the Babinski sign, describes the method and application of quantitative bedside olfactory testing, and discusses smartphone apps to improve the sensitivity of the examination. Psychiatric Care of the Medical Patient, 3rd Edition provides concepts and information to facilitate the dialogue between psychiatrists and general medical specialists - minimizing psychiatric jargon and speaking in the common language of caring and curious physicians.

Intussusception is the most frequent cause of bowel obstruction in infants and toddlers. In this book, the symptoms and clinical findings of intussuception are discussed. The clinical guidelines for the management of intussuceptions in children are discussed as well. Other chapters examine the diagnosis, etiology, pathophysiology and treatment modalities for both small bowel obstruction and intussusception of the small bowel, focusing on minimally invasive surgical options; the etiology of afferent loop obstruction; the treatment options for adhesive small bowel obstruction (SBO), a common complication typically caused by adhesions that form after abdominal surgery; a literature review of traditional medical treatment options and a discussion on the authors'experiences in treating gynecological cancer patients with non-malignant bowel obstruction using manual physical therapy.

In contrast to the institutional approach of years past, today most people with mental illness live in the community, and decide for themselves whether, and to what extent, to participate in treatment. Providers are now beginning to ask, How do I provide services that help people achieve their recovery goals? rather than, How do I get my patient to adhere to the prescribed treatment? Contributors to this volume describe the public health benefits that emerge when providers respect personal health care decisions even when the person making them has a serious mental illness. They also share evidence-based practices that enhance self-determination, such as creating an advance psychiatric directive, addressing clients information processing difficulties so they can better understand their treatment options, and motivational interviewing to support employment as part of a recovery plan. Rich examples of consumer-provider interactions illustrate how providers can instill hope and help activate the client s support.

This work presents some recent clinical, epidemiological and experimental data on the cancer preventive effect of healthy hormonal equilibrium. Insulin resistance-associated overproduction of peptide hormones, such as growth hormone, insulin and insulin-like growth factors, interacting simply with cell membrane receptors, have a proven tumor inducing capacity. Another group of hormones, including estrogens, thyroids and vitamin D, has both genomic intranuclear and non-genomic membrane-associated receptor signaling, thus they have complex roles in all basic cellular functions. Recent results suggest that defective synthesis of these latter hormones or alterations of their signal transduction pathways may thoroughly disturb metabolic processes, reproduction and the regulation of cell proliferation. Primary cancer prevention based on the preservation or restoration of the hormonal and metabolic equilibrium of patients may be the main program of the anticancer fight in the 21st century. Moreover, in cases with diagnosed malignancy, we should cure the ill patients instead of their tumors. After surgical tumor removal, the achievement of hormonal and metabolic equilibrium restores the natural defense mechanisms of patients, which may help to stop tumor recurrence. (Nova Biomedical)

Lung cancer is the most common and most lethal malignancy worldwide, causing 1.4 million diseases every year. Half of non-small cell lung cancers (NSCLC) are diagnosed at such an advanced stage that a cure cannot be considered a realistic aim, and over 75% of cases selected for a curative treatment eventually relapse within five years. The 5-year overall survival rates are less than 20% for NSCLC patients. As a disease, NSCLC demands our maximum abilities as researchers, physicians, and care-givers, and a continuous updating of our knowledge. Conventional chemotherapy for advanced NSCLC does not provide a great long-term benefit in terms of survival. Accordingly, a different therapeutic approach has to be explored. The human epidermal growth factor family of surface receptors (HER) became a critical target to be investigated. The epidermal growth factor receptor (EGFR) is overexpressed in over 80% of non-small cell lung cancer. The presence of sensitizing conformational mutations in the EGFR increases the efficacy of modern tyrosine kinase inhibitors against its inner portion (EGFR-TKI). The EGFR-TKIs greatly prolong disease-free survival of those patients harboring sensitizing EGFR mutations, and have been suggested as an essential tool in the therapeutic repertoire. This volume aims to serve as an updated compendium of biology and applications of anti-EGFR therapies, and offers a look at the future of anti-HER therapy in lung cancer. This volume exhaustively reviews and discusses: 1) the nature and significance of activating EGFR mutations, and those clinical and pathological phenomena related to HER alterations; 2) the most common laboratory methodologies to study EGFR, and the future of HER analysis; 3) the right time to analyze EGFR mutations and evolutionary changes in the HER; 4) EGFR-TKI application in unselected and selected NSCLC patients; 5) upcoming anti-HER therapies; 6) the eventual role of anti-HER therapies in early NSCLC; 7) mechanisms of acquired resistance to anti-HER therapies, and experimental and conventional strategies to bypass them; 8) the application of anti-HER therapies in other malignancies. This book is an indispensable handbook for all those specialists devoted to the diagnosis and management of lung cancer.

More and more people living with and beyond cancer seek integrative interventions to complement their conventional cancer care. This second edition of the highly successful Integrative Oncology provides the reader with the most updated information available with new chapters on Music and Expressive Arts Therapies, Naturopathic Oncology, and an integrative approach to Lung Cancer. Integrative medicine is defined as healing-oriented medicine that takes account of the whole person (body, mind, and spirit) as well as all aspects of lifestyle; it emphasizes the therapeutic relationship and makes use of appropriate therapies, both conventional and alternative. This series grows out of a need to organize and make accessible to clinicians the basic principles of integrative medicine in practical application to common health conditions. Each volume focuses on a particular specialty and features well-recognized and authoritative editors and chapter authors. The text is presented in an easy-to-read format featuring case histories, clinical pearls, and useful tables, with all key information highlighted. Series editor Andrew Weil, MD, is Professor and Director of the Arizona Center for Integrative Medicine at the University of Arizona. Dr. Weil's program was the first such academic program in the U.S., and its stated goal is'to combine the best ideas and practices of conventional and alternative medicine into cost effective treatments without embracing alternative practices uncritically.'