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Impact assessment research has developed theory-based approaches to trace the societal impact of scientific research. Impact assessment typically starts from the perspective of a research investment, organization, or project. Research users, non-academic actors involved in knowledge production, translation, and application, are well represented in many of these approaches. Researcher users are usually positioned as contributors to research, recipients of research outputs, or beneficiaries of research-driven outcomes. This paper argues that impact assessment would benefit from a more comprehensive understanding and analysis of research valorization processes from the user perspective. The first half of the paper reviews key impact assessment literature to identify how research users are positioned and portrayed in relation to valorization processes. In the second half of the paper, we use the results of this review to propose a set of principles to guide a systematic approach to constructing user perspectives on research impact. We suggest four concepts for operationalization of this approach. The paper concludes that the addition of a more comprehensive research user perspective on research valorization would complement and enhance existing impact assessment approaches.

This paper provides an introduction to this symposium issue on participatory action research in geographic teaching, learning and research. It introduces the themes of the symposium and contributions from the participating authors, and also offers additional discussion of the attendant benefits and challenges of using participatory action research within a pedagogic context. The authors begin by discussing the recent growth of participatory pedagogies in higher education, including service learning, research-based teaching and community-based research. They contend that participatory action research may be incorporated in all of these learner-centred and community-engaged pedagogies with beneficial outcomes for teaching, student learning and academic research; however, they advocate for its incorporation into research-oriented and research-based teaching strategies where possible. They also discuss some of the unique political, ethical and logistical challenges involved, and argue that an engagement with participatory action research in our teaching requires more than attention to methods, but, rather, a rethinking of theory-practice, teacher-student, and university-community relationships. They conclude with a brief discussion of the symposium and the authors' contributions. (Contains 1 table and 3 notes.)

Peer review is an umbrella term that refers to a class of selection and oversight practices, including the familiar mechanisms of the review of proposals submitted for funding, of manuscripts for scholarly publications, and of personnel qualifications and portfolios for selection and promotion. Peer review has long been a cornerstone of modern scientific method premised on the assumption that those within a discipline are best suited to assess the work of others within that field. As such, it is also frequently employed to evaluate proposals submitted for professional meetings such as the annual conference of the American Evaluation Association (AEA). This paper presents a blind peer review method developed by AEA's Graduate Student & New Evaluators (GS&NE) Topical Interest Group (TIG) in an effort to construct an impartial and reliable process in proposal selection. Implications for conference review processes, AEA, and the field of evaluation in general are discussed. (Contains 2 tables and 1 endnote.)

Background/Context: In the last several decades, a college education, in particular the bachelor's degree, has become the key to higher earnings, and overall, to a middle-class lifestyle in the United States. In an increasingly globalized economy, privileging information and communication technologies, it is more than likely that this emphasis on higher education in the American labor market will continue in the future. While we know much about the increasing link between a college education and social mobility, writ large, we know considerably less about who actually makes the transition to college, how this occurs, and why. Despite the strides made, large numbers of individuals are not making the transition to college. Among those who are, there are important differences in the kinds of postsecondary institutions they are attending, and in completion rates, with attendant implications for social mobility. Purpose/Objective/Research Question/Focus of Study: This article has two purposes: (1) to synthesize the key facets of our knowledge base of how to expand the college pipeline and relatedly, to outline particular areas that have been under-examined across the disciplines; (2) to provide future directions that will allow us to better address this important inquiry along substantive and methodological lines. Research Design: This article draws on disciplinary papers commissioned by the Social Science Research Council's Transitions to College Committee. The discussion of preparation is framed around the contributions from the fields of anthropology, and political science; access vis-a-vis history, sociology, and demography; paying for college vis-a-vis economics; and completion vis-a-vis the field of higher education. Conclusions/Recommendations: The article calls for an overall integrative model, e.g., K-16 and interdisciplinary, improved coverage in large-scale datasets, and a more refined mixed methods approach to attend to notable gaps in our understandings of the transition to college. Across disciplines, a key substantive gap is variation along the lines of race, ethnicity, immigrant status, gender, and age across domains, which needs to be illuminated.

This paper examines the quality evaluations of the Greek Universities highlighting those which offer a full-fledged study program of primary education. There are eight principles-criteria according to which each university is evaluated. For each principle, scores may range from 1 (noncompliance with the principle) to 4 (fully compliance). I present and compare results of the Greek university evaluations completed by the Hellenic Quality Assurance and Accreditation Agency (HQA). Surprisingly, no university has been graded as non-compliant in any of the eight principles-criteria. These evaluations are performed by an alleged "external" and "independent" committee. For all practical purposes, they are, nevertheless, based on subjective and biased opinions of academics affiliated with international universities with links to Greece and its universities. Independent and evidence-based evaluations paint a different picture. Universities which get perfect scores in the quality evaluation processes perform badly in the pertinent international ranking systems. As a case study, their primary education departments have lower research performance with high variability between faculty members and departments. Given that one criterion of evaluating quality is research, then not all Greek universities can be evaluated as highly performing research institutions, either in absolute or relevant terms. This criterion of quality is not satisfied by the primary education departments of Greek universities. According to this evidence, using the HQA as an agency to assess and accredit quality is useless. It should be abolished. A new system should be based on objective criteria such as independent teaching evaluations and research performance. These do not require any committee to evaluate performance and can be constructed on evidence-based policy. The latter relies solely on rigorously established objective facts.

The quality of a research study application sends a distinct signal to the institutional review board (IRB) about the skills, capacities, preparation, communication, experience, and resources of its authors. However, efforts to research and define IRB application quality have been insufficient. Inattention to the quality of an IRB application is consequential because the application precedes IRB review, and perceptions of quality between the two may be interrelated and interdependent. Without a clear understanding of quality, IRBs do not know how to define quality and researchers do not know how to achieve quality. This position has not been systematically studied to date, and future research could provide much-needed empirical validation. This paper lays the conceptual groundwork for future investigation into what constitutes quality in an IRB application. It includes a landscape review of multidisciplinary research on quality, as well as a discussion of quality frameworks analogous to research with human participants that exist in the published literature. It also examines the background and significance of federal research regulations, regulatory burdens, researchers' regulatory literacy, and the roles and responsibilities of IRB professionals within this ecosystem.

This paper is concerned with the process of selecting between the increasingly popular bi-factor model and the second-order factor model in measurement research. It is indicated that in certain settings widely used in empirical studies, the second-order model is nested in the bi-factor model and obtained from the latter after imposing appropriate parameter constraints. These restrictions can be directly tested within the framework of the latent variable modeling methodology employing widely circulated software. The outlined model selection procedure provides a readily applied means of choosing between the two models of growing interest to measurement scholars, and is illustrated using numerical data.

Although encompassing a variety of research approaches, qualitative research in music education shares the assumption that reality is socially constructed; it takes this construction to be based on the specific perspective of the individual human; and it considers epistemology and ontology to be different fields of study. The posthuman theory of agential realism, on the other hand, argues that the world is becoming through intra-actions; it decentres the individual humanist subject; and it studies onto-epistemology -- practices of knowing-in-being. Considering these fundamental differences, the quality criteria of qualitative research are not applicable to posthuman music education research. Nevertheless, posthuman research is concerned with the ethics of research and how to response-ably and ethically take part in the world's becoming. Thus, the emerging field of posthuman music education research must develop other ways of evaluating research beyond the quality criteria found in qualitative methodologies. This paper argues that diffraction -- both as a physical and musical phenomenon and as a philosophical concept -- might be a fruitful approach. By reading quality criteria diffractively through the agential realist concept of response-ability, it poses critical and creative questions, moving us towards evaluating the quality of posthuman music education research on its own terms.

Background: Research on evaluation use focuses on putting evaluation recommendations into practice. Prior theoretical research proposes varied frameworks for understanding the use (or lack) of program evaluation results. Purpose: Our purpose is to create and test a single, integrated framework for understanding evaluation use. This article relies on prior theoretical research regarding categories of utilization, typologies of recommendations, and factors affecting utilization to frame an empirical study of evaluation use that then tests the integrated theory. Setting: The empirical part of the article draws on post-evaluation interviews with sixteen agencies that have engaged in evaluation research. Subjects: The agencies are mostly local non-profits, but the sample also includes a state agency, a city agency, and two university-community partnerships. All agencies had undergone a program evaluation between 2003 and 2006. Intervention: Having participated in an evaluation is the main "intervention" of interest in this article, in which we consider the relationship between evaluation use theory and empirical evidence on the topic. Research Design: A qualitative approach, our research design involved examining each of the sixteen agencies within two years of their having been evaluated. Data Collection and Analysis: Data collection included structured in-person interviews with at least one key informant in each agency. In addition, a short, closed-ended survey was administered to research participants. Interview data were analyzed using content analysis of themes and grouping agencies according to their evaluation's outcomes (favorable or not) and experiences. Survey data were analyzed with simple descriptive statistics and similarly involved a subgroup analysis, according to agencies' reported use of evaluation. Findings: Most evaluation use is conceptual, and few agencies studied actually implemented specific evaluation recommendations. Agencies perceived recommendations as changes to rules and structure, which theory and prior research suggest suppresses use. An important human factor that influenced evaluation use was minimal post-evaluation interaction with evaluators. Some long-term influence of the evaluation is evident, but only as conceptual and not as instrumental. In fact, very little instrumental use existed in this empirical assessment. Conclusions: Evidence suggests that evaluation use in practice aligns with theory, specifically emphasizing the conceptual use dimension. The proposed integrated model of prior evaluation use theories may hold value for future theoretical and empirical work. (Contains 1 figure, 3 tables and 2 footnotes.)

The article is concerned with the research approaches and nature of methodologies and epistemologies used by practitioner-researchers in a range of occupational areas. The authors use the experiences of candidates on a generic Doctorate in Professional Studies who undertake a module on research and development for professional practice. They also bring their experience as tutors and programme leaders and the results from focus groups with their peers in other universities to this current and topical area of the higher education curriculum. Part of the module asks candidates to write an assignment in which they investigate the methodologies and epistemologies used as a practitioner-researcher. A close analysis of ten of these assignments reveals that the methodologies selected for practice-based projects may be as a result of the candidates' personal, professional and disciplinary backgrounds as well as a time imperative and desire for brevity that arises from an immediacy in the situation. The authors also conclude that a range of factors were important to the practitioner-researchers and that these have important epistemological implications. The social-science-oriented approaches introduced on the programme offer tried and tested ways to research, but more practice-based approaches to practitioner-research could be developed further. (Contains 2 figures.)

Background/Context: Prior research on the challenges of college going and retention among adolescents today, particularly low-income, minority, and first-generation college-going youth, provide the context for this article. Purpose/Objective/Research Question/Focus of Study: This article sets the stage for the special issue articles by framing the issue's purpose and content. The purpose is to synthesize existing research and knowledge about the adolescent college transition from multiple disciplines and fields, in order to develop a more robust foundation for further research and policy development. The article also describes the knowledge development process used by the Social Science Research Council and its advisory committee to support field and discipline based literature reviews and to synthesize their implications over an 18 month period. Findings/Results: The article provides a summary of the articles presented in the special issue and a summary of the committee's recommendations, as framed in a separate publication, Questions That Matter. It explains that the six discipline and field-based essays (history, demography, anthropology, sociology, economics, and higher education) presented in the special issue reflect a discussion of the organization of research in each field and characterizes the contributions of each field to our understanding of transitions. Together these are a rich collection of essays that map the state of the respective fields by identifying key topics and the research questions posed. Conclusions/Recommendations: The authors conclude by drawing attention to two primary points: key elements of the challenge to improvements in research and persisting conceptual issues that challenge research, policy and practice.

Background: Previous research has found that a "web-push" approach to data collection, which involves contacting people by mail to request an Internet survey response while withholding a paper response option until later in the contact process, consistently achieves lower response rates than a "paper-only" approach, whereby all respondents are contacted and requested to respond by mail.Method: An experiment was designed, as part of the Millennium Cohort Family Study, to compare response rates, sample representativeness, and cost between a web-push and a paper-only approach; each approach comprised 3 stages of mail contacts. The invited sample (n = 4,935) consisted of spouses married to U.S. Service members, who had been serving in the military between 2 and 5 years as of October, 2011.Results: The web-push methodology produced a significantly higher response rate, 32.8% compared to 27.8%. Each of the 3 stages of postal contact significantly contributed to response for both treatments with 87.1% of the web-push responses received over the Internet. The per-respondent cost of the paper-only treatment was almost 40% higher than the web-push treatment group. Analyses revealed no meaningfully significant differences between treatment groups in representation.Conclusion: These results provide evidence that a web-push methodology is more effective and less expensive than a paper-only approach among young military spouses, perhaps due to their heavy reliance on the internet, and we suggest that this approach may be more effective with the general population as they become more uniformly internet savvy. [ABSTRACT FROM AUTHOR]

Purpose: The purpose of this study is to systematically review the practice of reverse mentoring and draw a timeline of the research over the past two decades. Considering the novelty of this intervention, this paper proposed an agenda for future research on this burgeoning topic. Design/methodology/approach: By adopting narrative literature review and Gregory and Denniss' (2018) four-step process, this paper reviewed 54 studies grounded in conceptual, literature review and empirical research published between 1998 and 2020. Findings: The articles included in the literature review on reverse mentoring research were summarized according to journal publications, research methodologies, contextual settings, theoretical framework, purpose and outcomes. Reverse mentoring studies are dominantly published in educational journals using primarily qualitative and conceptual approaches to explore both academic and business contexts within the USA and Europe. Theories frequently used to frame and examine the need of reverse mentoring included social exchange theory and leader-member exchange theory. The fundamental purpose of reverse mentoring research is to transfer knowledge and to bridge the technology divide between intergenerational groups. Reverse mentoring has been used to promote inclusivity between multiple generations in relation to gender, ethnicity and culture. Originality/value: As per the knowledge, this is the first-ever comprehensive English summary of reverse mentoring research done in the past two decades. Findings from this research can be used to better understand reverse mentoring research trends and directions.

The purpose of this research is to make a meta-evaluation of the program evaluation studies on teacher training programs in Turkey. Meta-evaluation is the process of revealing the deficiencies and errors of the research as the last stage of the program evaluation process. In this context, the steps of the meta-evaluation processes were followed methodically. In the in this research, 9 program evaluation studies conducted between 2010 and 2020 about teacher training programs, using any program evaluation approach and model, were meta-evaluated. The sampling method of the research is criterion sampling.. Research data was collected using the "Program Evaluation Standards Checklist" developed by the researchers. During the development of the relevant data collection tool, the "Program Evaluation Standards" created by the Joint Committee on Standards for Educational Evaluation (JCSEE) were benefited. The studies included in the research were examined by 6 program experts who formed the meta-evaluation team. Each expert evaluated 3 studies using the checklist. Research data was analyzed using descriptive analysis method. Research findings indicate that the examined program evaluation studies meet the program evaluation standards by 55.67%. From this point, some suggestions that are believed to contribute to future program evaluation and meta-evaluation studies on teacher training were presented. [This study was an oral presentation in "International Pegem Conference on Education", Diyarbakir, Türkiye, 16-18 September 2020.]

This paper provides an introduction to issues surrounding the participation rights of young people in research and the implications of their growing involvement in research as well as providing a discourse on the ethical implications related to consent. The unique contribution of this paper is that it considers children’s rights in respect to the increasing opportunities for young people to take part in evaluation research. The aim of this paper, therefore, is to acknowledge the growing involvement for young people in research and the implications of ensuring that their rights of participation are respected. Secondly, we will consider the children’s rights legislation and our obligations as researchers to implement this. Finally, we will explore consent as an issue in its own right as well as the practicalities of accessing participants. This paper will postulate that any research about young people should involve and prioritize at all stages of the research process; including participation in decision-making. We conclude by identifying five key principles, which we believe can help to facilitate the fulfilment of post-primary pupils’ ability to consent to participate in trials and evaluative research. [ABSTRACT FROM AUTHOR]

We study the role of gender in the evaluation of economic research using submissions to four leading journals. We find that referee gender has no effect on the relative assessment of female- versus male-authored papers, suggesting that any differential biases of male referees are negligible. To determine whether referees as a whole impose different standards for female authors, we compare citations for female- and male-authored papers, holding constant referee evaluations and other characteristics. We find that female-authored papers receive about 25% more citations than observably similar male-authored papers. Editors largely follow the referees, resulting in a 1.7 percentage point lower probability of a revise and resubmit verdict for papers with female authors relative to a citation-maximizing benchmark. In their desk rejection decisions, editors treat female authors more favorably, though they still impose a higher bar than would be implied by citation maximization. We find no differences in the informativeness of female versus male referees or in the weight that editors place on the recommendations of female versus male referees. We also find no differences in editorial delays for female- versus male-authored papers. [ABSTRACT FROM AUTHOR]

Background: When a journal receives a duplicate publication, the ability to identify the submitted work as previously published, and reject it, is an assay to publication ethics best practices. The aim of this study was to evaluate how three different types of journals, namely open access (OA) journals, subscription-based journals, and presumed predatory journals, responded to receiving a previously published manuscript for review.Methods: We performed a quasi-experimental study in which we submitted a previously published article to a random sample of 602 biomedical journals, roughly 200 journals from each journal type sampled: OA journals, subscription-based journals, and presumed predatory journals. Three hundred and three journals received a Word version in manuscript format, while 299 journals received the formatted publisher's PDF version of the published article. We then recorded responses to the submission received after approximately 1 month. Responses were reviewed, extracted, and coded in duplicate. Our primary outcome was the rate of rejection of the two types of submitted articles (PDF vs Word) within our three journal types.Results: We received correspondence back from 308 (51.1%) journals within our study timeline (32 days); (N = 46 predatory journals, N = 127 OA journals, N = 135 subscription-based journals). Of the journals that responded, 153 received the Word version of the paper, while 155 received the PDF version. Four journals (1.3%) accepted our paper, 291 (94.5%) journals rejected the paper, and 13 (4.2%) requested a revision. A chi-square test looking at journal type, and submission type, was significant (χ2 (4) = 23.50, p < 0.001). All four responses to accept our article came from presumed predatory journals, 3 of which received the Word format and 1 that received the PDF format. Less than half of journals that rejected our submissions did so because they identified ethical issues such as plagiarism with the manuscript (133 (45.7%)).Conclusion: Few journals accepted our submitted paper. However, our findings suggest that all three types of journals may not have adequate safeguards in place to recognize and act on plagiarism or duplicate submissions. [ABSTRACT FROM AUTHOR]

Although robust evidence has been accumulating over the last decades supporting the effectiveness of career counseling in various populations, yet there are scarce conceptual or empirical studies investigating the impact of distinct approaches, such as traditional-"psychometric," narrative, or a mixed (integrative) one. The primary aim of this paper is to make a contribution in the field, providing a synthetic overview of contemporary research findings regarding the effectiveness of narrative and mixed career counseling approaches with a special focus on university students. The recent trend of utilizing mixed approaches in career assessment and intervention is also emphasized in the article, suggesting they may have a great potential in helping young adults advance meaning-making about career and life design. Finally, a discussion of both benefits and challenges relating to narrative and mixed interventions along with recommendations for extending research in the area of assessing career interventions' effectiveness for university students is provided.

Purpose: This study compared a tablet PC questionnaire with a paper method for reliability and patient preferences in the acquisition of patient-reported outcomes (PROs) for patients treated with radiotherapy. By comparing the two modes of PRO administration, we aimed to evaluate the adequacy of using tablet PC questionnaires in future clinical use.Methods: Patients were randomized in a crossover study design using two different methods for PRO entry. A group of 89 patients answered a paper questionnaire followed by the tablet PC version, whereas 89 patients in another group completed the tablet PC questionnaire followed by the paper version. Surveys were performed four times per patient throughout the course of the radiotherapy. The Korean versions of the M.D. Anderson Symptom Inventory (MDASI-K) and the Brief Fatigue Inventory (BFI-K) were used. The primary endpoint of our current study was an assessment of patient preference for the survey method. The proportions of patients preferring each mode of questionnaire were evaluated.Results: The proportion of patients who preferred the tablet PC version, paper form, or who had no preference was 52.2, 22.1, and 25.7 %, respectively. More than half of the patients preferred the tablet PC to the paper version in all four surveys. Age, gender, educational status, prior experience of using a tablet PC, and the order of paper to tablet PC administration did not impact patient preferences. Inter-class correlation coefficients (ICCs) between the modes were 0.92 for MDASI-K and 0.94 for BFI-K and ranged from 0.91 to 0.96 on both instruments during the four surveys.Conclusions: A tablet PC-based PRO is an acceptable and reliable method compared with paper-based data collection for Korean patients receiving radiotherapy. [ABSTRACT FROM AUTHOR]

Background: The essence of humanism in medicine and health care is relationships-caring relationships between clinicians and patients. While raising concerns regarding professional-patient boundaries has positively contributed to our understanding and prevention of potentially harmful boundary violations, there is controversy about which types of relationships, caring acts, and practices are acceptable versus cross boundary lines.Objective: To examine primary care physicians' practices and attitudes regarding acts that have been questioned as potentially "inappropriate" or "unethical" crossing of professional-patient boundaries.Design: Surveys conducted via in-person polling or electronic and mailed paper submissions from April 2016 to July 2017. We calculated descriptive statistics and examined associations with practices and attitudes using logistic regression.Participants: Random sample of all US primary care physicians who treat adult patients; convenience sample of attendees at medicine grand rounds presentations.Main Measures: Outcomes were self-reported practices and attitudes related to giving patients rides home, paying for patients' medication, helping patients find jobs, employing patients, going to dinner with patients, and providing care to personal friends.Key Results: Among 1563 total respondents, 34% had given a ride home, 34% had paid for medications, 15% helped patients find a job, 7% had employed a patient, 10% had dinner with patients, and 59% provided care to personal friends. A majority disapproved of dinner with a patient (75%) but approved of or were neutral on all other scenarios (61-90%).Conclusions: The medical profession is quite divided on questions related to drawing lines about appropriate boundaries. Contrary to official and widespread proscriptions against such practices (with exception of dinner dates), many have actually engaged in such practices and the majority found them acceptable. [ABSTRACT FROM AUTHOR]

Cysticercosis is an infestation of Cysticercus cellulosae. When it occurs in the brain, chronic neurological complications can ensue, most commonly seizures. Neurocysticercosis is usually diagnosed by neuroimaging, a technique not available in most endemic countries. Hence immunological tests are valuable for diagnosis and epidemiological surveys. We evaluated the suitability of paper for storing blood and cerebrospinal fluid (CSF) until subsequent testing by enzyme-linked immunosorbent assay (ELISA), by testing whole blood samples on filter paper from 305 patients and CSF samples from 117 patients stored on ordinary white typing paper and on filter paper. Optimal preservation of biological samples is achieved when whole blood is stored on filter paper, CSF on white paper, and when samples are frozen within 1 week after collection. Our results could improve diagnostic capabilities and facilitate epidemiological surveys in endemic countries where immunodiagnostic tests cannot be rapidly performed because of inadequate laboratory infrastructure. [ABSTRACT FROM AUTHOR]

This paper evaluates how technical assistive devices for manual materials handling were analysed in the literature in a warehousing context. Works that discuss the economic and/or human factors impact of assistive devices on the warehousing system or the people employed therein were identified in a systematic literature review. Building on a conceptual framework proposed in this paper, our evaluation of the literature shows which types of assistive devices were analysed in the past, and from which perspective these devices were examined. Some works studied the devices exclusively from an operator well-being or an efficiency perspective, while several works analysed the devices' performance in terms of both dimensions. Several works contained in our literature sample highlighted trade-offs between both ergonomic and economic measures and, within the first category, between alternative ergonomic indicators, which shows that assistive devices have to be evaluated carefully in light of their intended application. The paper further identifies research gaps and emphasises the need to understand the interactions between human- and system-related variables that can be supported by assistive devices in designing effective manual materials handling systems. [ABSTRACT FROM AUTHOR]

The issue of connecting research evidence with practice referred to as evidence-informed practice (EIP) has received considerable critical attention in the field of education. However, assessment literature has failed to fully acknowledge the significance of this issue. This conceptual paper concentrates on the process of informing classroom assessment practices by policy-makers, researchers, and teachers. It draws on the important literature on EIP in education and its scarce literature in assessment to highlight a possible productive relationship between assessment research and practice. The paper aims to propose a set of principles as to address the tension between AfL research and practice by defining the roles of each party in the process based on cultural and contextual issues. Accordingly, a cyclical process of collaborative research conduction is proposed. This process provides policy-makers, researchers and practitioners with important implications for practicing AfL research evidence.

Background/objectives: The growing interest of medical community about sarcopenia resulted in the production of several clinical practice guidelines (CPGs), with an unavoidable variability in terms of the overall quality of those publications. Our aim is to evaluate the quality of CPGs on sarcopenia using the AGREE II instrument.Subjects/methods: We performed an online literature search for sarcopenia CPGs using different databases. Four independent reviewers evaluated the quality of CPGs using the AGREE II instrument. To classify the quality of each guideline, we defined specific thresholds of final score: high-quality if five or more domains scored >60%; average-quality if three or four domains scored >60%; low-quality if ≤2 domains scored >60%.Results: Our literature search yielded 315 articles, and after applying exclusion criteria our final analysis included 19 CPGs. The overall quality of CPGs was remarkable, as 13/19 (68.4%) were considered of "high-quality" CPGs, with more than four domains reached a score higher than 60%. "Scope and Purpose" and "Clarity of Presentations" had the best domain results (78.4% and 73.8%, respectively), while the two domains with the lowest scores were "Rigor of Development" and "Applicability" (61.5% and 58.7%, respectively). Interobserver variability ranged between moderate (0.624) and fair (0.275).Conclusions: Our study showed that the overall quality of CPGs about sarcopenia was noteworthy, as more than two-third of paper obtained a "high-quality" score. The domain "applicability" had the lowest score, suggesting that emphasis should be put on possible strategies for helping other doctors to implement guideline recommendations in clinical practice. [ABSTRACT FROM AUTHOR]

Purpose: The aim of the present study is to comparatively evaluate the anti-inflammatory and antiapoptotic effects of bone marrow and adipose-derived mesenchymal stem cells (MSCs) applied subconjunctivally after alkaline corneal burn. Methods: Thirty-two rats were divided into 4 groups and included in the study (n = 8). While no intervention was made in the control group, a chemical burn was created by applying 4 μL of NaOH soaked in 6 mm filter paper to the right eye of each subject in the other groups under general anesthesia. While only subconjunctival 0.1 mL phosphate-buffered saline (PBS) was injected to in the group 1, 2 × 106 adipose or bone marrow-derived MSC in 0.1 mL PBS was applied subconjunctivally to the subjects in the remaining groups (Group 2 and 3, respectively). Tissue samples were collected for histological analysis on the third day after the burn. Tissue samples were evaluated light microscopically and immunohistochemically stained for interleukin-1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), caspase-3 (Cas-3), and CD68. Results: The IL-1β and TNF-α staining scores and the number of CD68- and Cas-3-positive stained cells were significantly lower in the groups given bone marrow and adipose-derived MSC compared to the alkaline burn group (P < 0.0001, for all parameters). Epithelial IL-1β and TNF-α staining scores were significantly lower in the bone marrow-derived MSC group compared to the adipose-derived MSC group (P < 0.0001, for all parameters). Conclusions: The presented study shows that both bone-marrow and adipose-derived MSCs support wound healing in the corneal tissue and strongly suppress the inflammation occured in the tissue. [ABSTRACT FROM AUTHOR]

We study gender differences in the evaluation of submissions to economics conferences. Using data on more than 9,000 submissions from the Annual Congress of the European Economic Association (2015–17), the Annual Meeting of the Spanish Economic Association (2012–17) and the Spring Meeting of Young Economists (2018), we find that all‐female‐authored papers are 3.3% points (p.p.), or 6.8%, less likely to be accepted than all‐male‐authored papers. The estimated gap ranges from 5.4 p.p. (95% CI: 2.5 p.p., 8.3 p.p.) to 2.9 p.p. (0 p.p., 5.8 p.p.). This gap is present after controlling for number of authors of the paper; field; referee fixed effects; cites of the paper; authors' previous publication record, affiliations, and experience; and connections between the authors of a given paper and the referees that evaluate it. We provide evidence suggesting that the gap is driven by stereotypes against female authors: it is entirely driven by male referees, only exists for lesser‐known authors, and seems larger in more masculine fields, especially in finance. [ABSTRACT FROM AUTHOR]