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Cathleen M McCabe,1 Rachael Peterson,2 Jessie Hull,2 Chandra Bala3 1The Eye Associates, Sarasota, FL, USA; 2Alcon Vision LLC, Fort Worth, TX, USA; 3PersonalEyes, Sydney, NSW, AustraliaCorrespondence: Cathleen M McCabe, The Eye Associates, Sarasota County, 2111 Bee Ridge Road, Sarasota, FL, 34239, USA, Email cmccabe13@hotmail.comPurpose: To evaluate binocular intermediate visual acuity (IVA), depth of focus, and other visual outcomes achieved with a monofocal aspheric intraocular lens (IOL) using pooled data from 2 randomized, double-masked, controlled trials.Patients and Methods: The studies conducted at 32 sites included patients aged ≥ 22 years with bilateral cataracts, preoperative corneal astigmatism 1.0 D, and lens power 18.0– 25.0 D. Patients received bilateral AcrySof IQ IOLs (SN60WF). Primary endpoint data were collected at month 6. Binocular uncorrected and corrected distance visual acuity (UDVA and CDVA) at 4 m, binocular uncorrected and corrected IVA (UIVA and DCIVA) at 66 cm, manifest refraction spherical equivalent (MRSE), and binocular defocus curve at 4 m were assessed under photopic conditions. Validated questionnaires were used to assess spectacle use and quality of vision.Results: Of 233 patients who received SN60WF, 228 had visual acuity data at 6 months. Under photopic conditions, 51% of the eyes had pupils > 4 mm, 40% had pupils 3– 4 mm, and 9% had pupils < 3 mm. Mean ± SD UDVA and CDVA were − 0.019 ± 0.110 and − 0.088 ± 0.082 logMAR, respectively. Mean ± SD UIVA and DCIVA were 0.125 ± 0.145 and 0.196 ± 0.139 logMAR, respectively. UIVA and DCIVA of 20/32 or better were achieved by 83% (188/228) and 71% (162/228) of patients, respectively. Mean ± SD MRSE was − 0.007 ± 0.404 D for the first eye and 0.036 ± 0.371 for the second eye. The defocus curve demonstrated binocular vision of 0.24 logMAR or better from +1.2 to − 1.5 D. Spectacle independence for distance and intermediate vision was reported by 86% and 41% of the patients, respectively. Based on questionnaires, 61%, 79%, and 65% of the patients did not experience starbursts, halos, or glare.Conclusion: A monofocal aspheric IOL (SN60WF) assessed in a large, pooled study provided excellent distance vision and clinically functional intermediate vision.Keywords: Intermediate visual acuity, monofocal aspheric intraocular lens, spectacle Independence, visual quality

Purpose The aim of this study was to determine the effectiveness of a novel innovative monofocal intraocular lens (Tecnis Eyhance ICB00) compared with the standard monofocal lens (Tecnis-1-piece ZCB00) in terms of contrast sensitivity, postoperative refraction, intermediate visual acuity (VA), and uncorrected and best-corrected distance VA. Patients and methods This prospective comparative interventional clinical study was conducted from January 2021 to November 2021. It included 40 eyes of 20 patients who were divided into two groups, with 10 patients each. Candidates for bilateral cataract extraction by phacoemulsification were included in this study and underwent thorough preoperative examination and postoperative evaluation at 3 months after the second eye operation. The outcome measures included intermediate and distance VA, near add, contrast sensitivity, and incidence of photic phenomena, which was evaluated using a printed questionnaire. The binocular defocus curves were analyzed. Results The study included 20 patients (seven males and 13 females). Binocular and monocular uncorrected and corrected distance VAs were statistically similar in both groups. The Eyhance group demonstrated significantly higher binocular uncorrected and corrected intermediate VA compared with the TECNIS 1-piece group (P

J Morgan Micheletti,1 Nicole B Duncan,2 Brad Hall3 1Berkeley Eye Center, Houston, TX, USA; 2Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA; 3Sengi, Penniac, NB, CanadaCorrespondence: J Morgan Micheletti, Berkeley Eye Center 3100 Weslayan, Suite 400, Houston, TX, 77027, USA, Tel +1-713-526-1600, Email morgan.micheletti@berkeleyeye.comPurpose: To compare intermediate visual outcomes in patients previously implanted with bilateral Clareon monofocal IOLs versus bilateral Eyhance IOLs.Methods: This was a non-interventional, single-center, examiner-masked, comparative study. Participants were cataract patients presenting at least 3 months after uncomplicated, bilateral implantation of either Clareon or Eyhance non-toric and toric IOLs. Outcomes measures included binocular distance-corrected intermediate visual acuity (DCIVA), binocular corrected distance visual acuity (CDVA), binocular best-corrected defocus curve, postoperative mean residual spherical equivalent (MRSE), and residual astigmatism.Results: A total of 620 eyes of 310 subjects (155 subjects per group) were evaluated. The mean difference in DCIVA was 0.05 logMAR between the Eyhance and Clareon IOLs which was significant (p < 0.01), but within the 0.1 logMAR non-inferiority margin. Mean CDVA of the Clareon group was 0.01 ± 0.03 logMAR compared to 0.02 ± 0.03 logMAR of the Eyhance Group (p > 0.05). Defocus curves from +1.0 D to – 3.0 D were not clinically nor statistically different between the Clareon and Eyhance groups (p > 0.05).Conclusion: The results of this study show that bilateral implantation of Clareon monofocal IOLs and Eyhance monofocal IOLs lead to similar distance and intermediate visual outcomes.Plain Language Summary: The natural lens inside the eye can become opaque. Cataract surgery removes this lens and replaces it with an artificial intraocular lens (IOL). The most often used type of intraocular lenses are monofocal lenses. These lenses provide clear vision for viewing distant objects. Increasing attention is also being paid to how these monofocal lenses perform for viewing objects at intermediate distances (such as using a digital device). The purpose of this study was to compare visual outcomes in patients with bilateral implantation of two different types of monofocal lenses, one of which was specifically designed to increase depth of focus. The results of this study suggest that implantation with these monofocal IOLs led to similar visual outcomes and that both monofocal IOLs may provide a similar potential to improve vision at the intermediate range.Keywords: Clareon, Eyhance, monofocal, intermediate visual acuity

J Morgan Micheletti,1 Matthew B McCauley,1 Nicole Duncan,2 Brad Hall3 1Berkeley Eye Center, Houston, TX, USA; 2Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA; 3Sengi, Penniac, NB, CanadaCorrespondence: J Morgan Micheletti, Berkeley Eye Center, 3100 Weslayan, Suite 400, Houston, TX, 77027, USA, Tel +1-713-526-1600, Email morgan.micheletti@gmail.comPurpose: To determine refractive or biometric variables that might be predictive of increased intermediate vision in patients receiving an Eyhance monofocal intraocular lens (IOL).Methods: This prospective, single-center, bilateral, non-randomized, open-label, observational study included a total of 110 subjects (220 eyes). Subjects had been previously bilaterally implanted with an Eyhance monofocal IOL (Johnson & Johnson Vision Care, Inc.) and were later divided into 2 groups based on their postoperative visual acuity. Subjects that had binocular distance corrected intermediate visual acuity (DCIVA) of 0.2 logMAR or better were classified into the Enhanced Group, and the remaining subjects were classified into the Non-Enhanced Group. Refractive outcomes and biometric measurements were compared between groups.Results: The number of subjects in each group was 61 for the Enhanced Group, and 49 for the Non-Enhanced Group. There were significant differences in pupil size between groups, with pupil sizes in the Enhanced Group significantly smaller than in the Non-Enhanced Group (p < 0.01). Subjects also reported significantly more dysphotopsias in the Non-Enhanced Group compared to the Enhanced Group (p = 0.03). Multiple regression analysis identified pupil size and axial length as significant predictors of increased monocular intermediate vision.Conclusion: The results of this study suggest that pupil size could be a predictor of increased intermediate vision in a patient receiving an Eyhance monofocal IOL.Plain Language Summary: Cataract surgery involves removing an opaque natural lens and replacing it with a clear artificial lens. These artificial lenses are called intraocular lenses (IOLs). There are many different types of IOLs, and each type provides varying degrees of clear vision at far, intermediate, and near distances. Clear vision at intermediate distance is especially important for viewing digital devices. One type of monofocal IOL, the Eyhance (Johnson & Johnson Vision Care, Inc.) was designed to improve the depth of focus. However, it is not well understood why some patients experience increased intermediate vision and some patients do not. The purpose of this study was to determine refractive or biometric variables that might be predictive of increased intermediate vision in patients receiving an Eyhance monofocal IOL. The results of this study suggest that pupil size could be a predictor of increased intermediate vision, and patients with smaller pupils may be more likely to experience increased intermediate vision.Keywords: cataract surgery, Eyhance, aspheric, intermediate visual acuity

Background: The aim of this study was to determine the repeatability of an automated-ETDRS (Early Treatment Diabetic Retinopathy Study) near and intermediate visual acuity measurement in subjects with normal visual acuity and subjects with reduced visual acuity. The agreement of automated-ETDRS with gold standard chart-based visual acuity measurement was also studied., Methods: Fifty-one subjects were tested (aged 23 to 91 years; 33 subjects with normal visual acuity: 6/7.5 or better; 18 subjects with reduced visual acuity: 6/9 to 6/30). Near and intermediate visual acuity of one eye from each subject was measured with an automated tablet-computer system (M&S Technologies, Inc.) and Precision Vision paper chart in a random sequence. Subjects were retested one week later. Repeatability was evaluated using the 95 per cent limits of agreement (LoA) between the two visits., Results: Average difference between automated-ETDRS near visual acuity and near visual acuity by paper chart was 0.02 ± 0.10 logMAR (p > 0.05). Agreement of near visual acuity between automated-ETDRS and paper chart was good, with 95 per cent LoA of ±0.19 logMAR. Furthermore, automated-ETDRS near visual acuity showed good repeatability (95 per cent LoA of ±0.20). Mean difference between automated-ETDRS intermediate visual acuity and intermediate visual acuity by paper chart was 0.02 ± 0.10 logMAR (p > 0.05). Agreement of intermediate visual acuity between automated-ETDRS and paper chart was good, with 95 per cent LoA of ±0.20 logMAR. In addition, automated-ETDRS intermediate visual acuity had good repeatability (95 per cent LoA of ±0.16)., Conclusion: Automated-ETDRS near and intermediate visual acuity measurement showed good repeatability and agreement with the gold standard chart-based visual acuity measurement. The findings of this study indicate the automated visual acuity measurement system may have potential for use in both patient care and clinical trials., (© 2019 Optometry Australia.)

The purpose was to determine the optimum negative spherical aberration induction required to improve near and intermediate visual acuity (VA) of presbyopic eyes. A total of 174 normal and diabetic (no retinopathy) presbyopic eyes (age ≥ 40 years) were measured with visual adaptive optics simulator (Voptica, Spain). First, baseline uncorrected VA and aberrations were measured. VA at 40 cm (near), 80 cm (intermediate) and distance was measured. Then, a negative spherical aberration (SA) was added to baseline ocular SA, and VA at all targets was reassessed after correction of distance refractive error. Clinically, baseline SA and root mean square of higher order aberrations were similar between the normal and diabetic presbyopic eyes. Baseline VA of the diabetic eyes at near and intermediate was better than the same of normal eyes (P = 0.001). After SA change, VA at near and intermediate of both normal and diabetic presbyopic eyes improved. However, fewer diabetic eyes needed higher SA change than normal eyes (P = 0.03). The corresponding trends with change in VA at near and intermediate were also similar between the normal and diabetic eyes. Patient-specific modulation of ocular SA to improve near and intermediate VA in a large cohort of eyes was successful in improving VA, sometimes even distance VA., (© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

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Purpose: To analyze the refractive and visual outcomes following cataract surgery and implantation of a new hydrophobic trifocal toric intraocular lens (IOL) in Japanese eyes with different degrees of corneal astigmatism. Methods: A total of 66 eyes from 39 patients implanted with a FineVision HP Toric IOL (Beaver-Visitec International Inc) were analyzed retrospectively. The main outcome measures considered were refraction, monocular uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected intermediate visual acuity (UIVA), and distance-corrected intermediate visual acuity (DCIVA) at 80 and 66 cm, uncorrected near visual acuity (UNVA) and distance-corrected near visual acuity (DCNVA) at 40 cm. Eyes were evaluated at three months post-surgery. Results: Sixty-five eyes (98.48%) were within ± 0.50D of spherical equivalent, and all were within ± 1.00D (mean: 0.00± 0.21D). Moreover, 63 eyes (95.45%) had ≤ 0.50D of residual astigmatism, and all had ≤ 1.00D (mean: – 0.08± 0.23D). Similarly, 58 (87.88%) and 60 eyes (90.91%) had ≥ 20/20 UDVA and CDVA, respectively, with 65 (98.48%) and 66 eyes (100%) achieving ≥ 20/25 UDVA and CDVA, respectively. In addition, 28 (42.42%) and 23 eyes (34.85%) had ≥ 20/25 DCIVA at 80 and 66 cm, respectively, with 49 (74.24%) and 52 eyes (78.79%) achieving ≥ 20/32 DCIVA at 80 and 66 cm, respectively. Finally, 39 (59.09%) and 40 eyes (60.61%) had ≥ 20/20 UNVA and DCNVA, respectively, with 58 (87.88%) and 59 eyes (89.39%) achieving ≥ 20/25 UNVA and DCNVA, respectively. Conclusion: Our study shows that implantation of the new hydrophobic FineVision HP Toric IOL results in accurate refractive outcomes, with good visual acuity at different distances, in Japanese eyes. [ABSTRACT FROM AUTHOR]

Purpose: To investigate the feasibility and safety of a new small-aperture device, which is implanted on top of the intraocular lens. Methods: Regular cataract surgery was performed in both eyes in 7 patients. In the non-dominant eye, a small-aperture device (VisionXtender; Morcher) was additionally implanted into the capsular bag at the end of the surgery. The mask had an inner diameter of 1.4 mm. Feasibility and safety were investigated 3 months and 2 years after surgery. Results: In all cases, the device was successfully positioned in the capsular bag without any intraoperative complications. No inflammation was observed at the 3-month follow-up visit. All patients achieved binocular uncorrected distance visual acuity of 0 logarithm of the minimum angle of resolution (log-MAR) or better. Additionally, distance-corrected intermediate visual acuity of 0.1 logMAR or better was measured in the non-dominant eye. Two years postoperatively, Nd:YAG capsulotomy was performed in three patients in both eyes. Conclusions: This clinical feasibility trial demonstrates that the use of the new small-aperture device is both easy and safe. No intraoperative or postoperative complications were reported. All patients attained satisfactory distance, intermediate, and near visual acuity. The device shows significant potential when used in combination with different intraocular lenses (eg, toric). In the future, different opening shapes seem to be possible. [J Refract Surg. 2024;40(9):e662–e666.] [ABSTRACT FROM AUTHOR]

Background: To evaluate the clinical outcomes and patient satisfaction after implantation of an enhanced monofocal intraocular lens (TECNIS Eyhance ICB00) in patients with idiopathic epiretinal membrane (ERM) who underwent cataract surgery with pars plana vitrectomy (PPV). Methods: This is a single-center, retrospective, comparative study. In total, 61 eyes of 61 patients with idiopathic ERM and cataracts were included. We measured the uncorrected near and intermediate visual acuity (UNVA and UIVA), uncorrected and corrected distance visual acuity (UDVA and CDVA), central macular thickness, defocus curves, and contrast sensitivity 3–6 months after the surgery. Overall patient satisfaction was assessed using a questionnaire at the 1-month follow-up visit. Results: The ICB00 group showed better near and intermediate visual acuity than the monofocal group (TECNIS ZCB00); however, no statistically significant differences were found between the groups. The ICB00 group exhibited wider defocus curves at near to far distances (−3.0 to +2.0 D) than the ZCB00 group. There were no significant differences in the results of the contrast sensitivity test, dysphotopsia, spectacle dependence, or patient satisfaction between the two groups. Conclusions: In combined PPV and cataract surgery for ERM patients, ICB00 resulted in good visual acuity with a smoother defocus curve compared to the ZCB00 group. [ABSTRACT FROM AUTHOR]

Purpose: To report the refractive and visual outcomes after implantation of a trifocal, diffractive, hydrophobic intraocular lens (IOL) in Japanese eyes following cataract surgery. Methods: A total of 45 eyes implanted with FineVision HP IOLs (Beaver-Visitec International, Inc. USA) were enrolled in this retrospective study. The clinical outcomes assessed after 3-months were refraction and monocular logarithm of the minimum angle of resolution (LogMAR) uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected intermediate visual acuity (UIVA), distance-corrected intermediate visual acuity (DCIVA) at 80 and 66 cm, uncorrected near visual acuity (UNVA), and distance-corrected near visual acuity (DCNVA) at 40 cm. Results: 97.78% of the eyes were within ± 0.50D of spherical equivalent and all of them were within ± 1.00D (mean: − 0.00± 0.22 D, with 75.56% within ± 0.13D), while 91.11% of the eyes had ≤ 0.50D residual astigmatism and all of them had ≤ 1.00D (mean: − 0.08± 0.24D, with 88.89% ≤ 0.25D). UDVA and CDVA showed mean values of − 0.05± 0.07 logMAR and − 0.07± 0.06 logMAR, respectively. 86.67% and 95.56% of the eyes had ≥ 20/20 UDVA and CDVA, respectively, with 100% achieving ≥ 20/25 for both UDVA and CDVA. At 80 cm, the mean monocular logMAR UIVA and DCIVA were 0.18± 0.14 and 0.14± 0.14, and at 66 cm the values were 0.20± 0.15 and 0.19± 0.15, respectively. At 80 cm 20% of the eyes had ≥ 20/25 DCIVA and 60% had ≥ 20/32 DCIVA. These values changed to 15.56% and 40% of the eyes at 66 cm. In terms of near vision, the mean monocular logMAR UNVA and DCNVA were 0.04± 0.10 and 0.03± 0.10, respectively. 53.33% of the eyes had ≥ 20/20 UNVA and DCNVA, with 86.67% achieving ≥ 20/25 UNVA and DCNVA. Conclusion: The FineVision HP trifocal diffractive IOL provided accurate refractive outcomes with good visual acuity at different distances in Japanese eyes. [ABSTRACT FROM AUTHOR]

Daniel H Chang Empire Eye and Laser Center, Bakersfield, CA, USA Purpose: The aim of the study is to evaluate the visual acuity and patient satisfaction at varied distances under photopic and mesopic lighting conditions in patients bilaterally implanted with aspheric diffractive multifocal one-piece intraocular lenses. Methods: In this retrospective–prospective study, 16 patients with a mean age of 66.2±9.2 years (range: 50–81 years) who had undergone bilateral phacoemulsification surgery with implantation of a Tecnis multifocal one-piece intraocular lens (ZMB00) were evaluated. Monocular and binocular uncorrected and distance-corrected visual acuities were measured at distance (20 ft), intermediate (70–80 cm), and near (35–40 cm) under photopic (85 cd/m2) and mesopic (3 cd/m2) lighting conditions and were compared using the paired t-test. All patients also completed a subjective questionnaire. Results: At a mean follow-up of 9.5±3.9 months, distance, near, and intermediate visual acuity improved significantly from preoperative acuity. Under photopic and mesopic conditions, 93.8% and 62.5% of patients, respectively, had binocular uncorrected intermediate visual acuity of 20/40 or better, and 62.5% and 31.3% of patients had binocular uncorrected near visual acuity of 20/20 or better. All patients were satisfied with their overall vision without using glasses and/or contact lenses when compared with before surgery. A total of 87.5% of patients reported no glare and 68.8% of patients reported no halos around lights at night. Conclusion: Tecnis multifocal one-piece intraocular lenses provide good distance, intermediate, and near visual acuity under photopic as well as mesopic lighting conditions. High levels of spectacle independence with low levels of photic phenomenon were achieved, resulting in excellent patient satisfaction. Keywords: Tecnis multifocal one-piece IOL, photopic visual acuity, mesopic visual acuity, intermediate visual acuity, near visual acuity

Purpose: To assess the visual and refractive outcomes of patients implanted with a toric extended depth-of-focus (EDOF) intraocular lens (IOL) following cataract surgery. Methods: A total of 44 eyes implanted with the EDOF LuxSmart toric IOL were evaluated 4 to 6 months postoperatively. The main outcomes measurements evaluated were refractive error, rotational stability, distance, intermediate, and near visual acuities, defocus curve, photopic and mesopic contrast sensitivity, wavefront aberrations, and modulation transfer function, and the Catquest-9SF-questionnaire. Results: The mean postoperative spherical equivalent and cylinder were −0.02 ± 0.26 and −0.17 ± 0.29 diopters (D), respectively. A total of 90.45% and 100% of the eyes had a postoperative spherical equivalent within ±0.50 and ±1.00 D, respectively (this being 93.18% and 100% for the refractive cylinder). The mean rotational stability was 0.61 ± 1.61 degrees. The mean binocular corrected distance visual acuity (CDVA), corrected distance intermediate visual acuity (CDIVA), and corrected distance near visual acuity (CDNVA) were −0.02 ± 0.06, 0.07 ± 0.08, and 0.26 ± 0.09 logMAR, respectively. The CDVA was 20/25 or better in 95.45% of patients, CDIVA was 20/25 or better in 72.73%, and CDNVA was 20/40 or better in 72.73%. The defocus curve showed good visual acuity at distance and intermediate vergences. The contrast sensitivity and optical quality outcomes were good with mean higher order, spherical, and coma aberration values of 0.161 ± 0.155, −0.019 ± 0.048, and 0.080 ± 0.065 µm, respectively. A total of 90.9% of patients were either fairly satisfied or very satisfied with their vision after the surgery, and 77.7% of patients reported no difficulties when reading text in newspapers. Conclusions: Implantation of the toric pure refractive EDOF technology IOL provides good refractive, optical, and visual quality at different distances, with high levels of patient satisfaction being reported. [J Refract Surg. 2024;40(6):e398–e406.] [ABSTRACT FROM AUTHOR]

Background: The results of implantation of refractive intraocular lenses (IOL), especially with an inferior segmental near add are of great interest due to advantages of the new lenses over more frequently used diffractive multifocal IOL. Aim: To assess the ocular optical performance of eyes implanted with a new IOL Lentis Mplus. Materials and methods: 78 patients (100 eyes) aged > 50 years were implanted with 100 IOLs Lentis Mplus. Preoperative examination included measuring uncorrected and corrected distance visual acuity, uncorrected and corrected near visual acuity. Postoperatively, uncorrected and corrected distance visual acuity, uncorrected and corrected near visual acuity (distance 33 cm) were estimated along with intermediate vision measurement using near-vision charts (60 cm). Results: On the day 3 after the procedure, distance visual acuity was good, and patients were able to near-reading of medium-size fonts. In 1 year, uncorrected visual acuity was 0.8–1.0 in two thirds of patients. 25% of patients needed distance visual correction from (-)0.5 to (-)0.75 D. Corrected visual acuity improved to 0.9–1.0. In 1 year, near visual acuity was 0.5 or more and intermediate visual acuity was 0.4 or more in all patients. In 78% of patients, 60 cm visual acuity was 0.5. Conclusion: Implantation of multifocal IOL Lentis Mplus produced good distance visual acuity and satisfactory (working) near and intermediate visual performance.

Purpose: To evaluate the visual outcome, light distortion index (LDI), and quality of life (QoL) of patients implanted with two complementary intraocular lenses (IOLs) to treat cataract and presbyopia. Methods: Twenty-seven consecutive patients with cataract were treated with the implantation of the Artis Symbiose Mid (Mid) IOL (Cristalens Industrie) in the distance-dominant eye and the Artis Symbiose Plus (Plus) IOL (Cristalens Industrie) in the contralateral eye following phacoemulsification. The primary objective was to ascertain the monocular and binocular defocus curves. Secondary endpoints included uncorrected distance visual acuity, corrected distance visual acuity, uncorrected intermediate visual acuity, and distance-corrected intermediate visual acuity at 90 and 70 cm, uncorrected near visual acuity and distance-corrected visual acuity at 40 cm, contrast sensitivity, LDI with a halometer, stereopsis, and patients' QoL with the validated Visual Function Index (VF-14) questionnaire. These measurements were collected in two visits, at 4.14 ± 3.13 and 10.30 ± 3.14 months postoperatively. Results: Statistically significant differences in the monocular defocus curves were found at the defocus steps of −1.00, −1.25, −1.50, −1.75, −2.50, −2.75, −3.00, −3.50 diopters and the −4.00 diopters (P <.050). The mean binocular defocus curve was 0 logMAR or better from the +0.50 to the −2.50 D defocus steps. Contrast sensitivity was within normal values. The LDI was 12.57 (6.61)% for the Mid eyes, 14.99 ± 5.70% for the Plus eyes, and 10.36 ± 4.42% binocularly. The patients' stereopsis was 40.0 (12.5) arc-seconds. The QoL score was 95.99 (7.14) at 10 months. Conclusions: The implantation of the Artis Symbiose IOLs was a safe and effective treatment for presbyopia compensation in patients with cataract. Both IOLs are complementary and may produce a binocular depth-of-field of 3.00 diopters over 0 logMAR when used together. [J Refract Surg. 2023;39(10):654–661.] [ABSTRACT FROM AUTHOR]